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Molecular Approaches to Isolating Opioid Receptors

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Neurobiology of Opioids

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Abstract

Opioid receptors were first identified in mammalian brain in the early 1970s (Pert and Snyder 1973; Simon et al. 1973; Terenius 1973), and their pharmacological properties have since been extensively characterized (for reviews, see Iwamoto and Martin 1981; Smith and Loh 1981; Wood 1982). However, full structural and functional characterization of a receptor requires its purification and reconstitution in membrane preparations; for several reasons, progress in this area of opioid receptor research has been relatively slow.

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Authors
  1. A. P. Smith
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  2. H. H. Loh
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Editors and Affiliations

  1. Department of Neuroendocrinology, Max Planck Institute for Psychiatry, Kraepelinstraße 2, D-8000, München 40, Germany

    Osborne F. X. Almeida

  2. Department of Neuropharmacology, Max Planck Institute for Psychiatry, D-8033, Martinsried, Germany

    Toni S. Shippenberg

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© 1991 Springer-Verlag Berlin Heidelberg

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Smith, A.P., Loh, H.H. (1991). Molecular Approaches to Isolating Opioid Receptors. In: Almeida, O.F.X., Shippenberg, T.S. (eds) Neurobiology of Opioids. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46660-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-46660-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46662-5

  • Online ISBN: 978-3-642-46660-1

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