Abstract
A necessary requirement in studying the function and regulation of the neurotransmitters and receptors of the brain is the careful delineation of their anatomical distributions. This detailed neurochemical mapping quickly becomes an overwhelming task, however, when the goal is to survey the entire brain. In view of the multiple receptor and neurotransmitter systems, a more meaningful and revealing approach is to examine the receptors and neurotransmitters within functionally and anatomically defined circuits. The basal ganglia provide a neuroanatomical system that is especially suited to this type of analysis. This system is well defined anatomically, in terms of the basic units which comprise it, demonstrates complex neurotransmitter-receptor interactions, and has been functionally implicated in sensory-motor integration and motivated behaviors.
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Mansour, A., Schafer, M.K.H., Newman, S.W., Watson, S.J. (1991). Central Distribution of Opioid Receptors: A Cross-Species Comparison of the Multiple Opioid Systems of the Basal Ganglia. In: Almeida, O.F.X., Shippenberg, T.S. (eds) Neurobiology of Opioids. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46660-1_10
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DOI: https://doi.org/10.1007/978-3-642-46660-1_10
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