Zusammenfassung
Für die vorzeitige Entwicklung der Gefäßarteriosklerose, die sich oft durch Herzinfarkt schon im mittleren Lebensalter manifestiert, spielen Fettstoffwechselstörungen und besonders erhöhte Blutcholesterinspiegel als ein eigenständiger primärer Risikofaktor eine bedeutende Rolle. Da jedoch die Blutfettwerte in offenbar gesunden Bevölkerungsgruppen stark variieren, kann es im Einzelfall oft schwierig sein, den Risikofaktor Hypercholesterinämie zu ermitteln. Als sicher pathologisch gelten Blutfettwerte, wenn sie eine Stoffwechselstörung selbst anzeigen, z. B. bei einer genetischen Hypercholesterinämie. In den westlichen Industriegesellschaften sind in der Bevölkerung insgesamt die Blutfette höher. Wir behelfen uns, indem wir Blutfettwerte jenseits der 95. Perzentile als pathologisch ansehen.
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© 1986 Springer-Verlag Berlin Heidelberg
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Schettler, G. (1986). Erhöhte Plasmalipide — ein Risikofaktor für die vorzeitige Arteriosklerose. In: Der Stoffwechsel der Plasmalipoproteine und seine Bedeutung für die Pathogenese der Arteriosklerose. Sitzungsberichte der Heidelberger Akademie der Wissenschaften, vol 1986 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46583-3_3
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