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EXAFS and XANES Studies of Fe and Zn in Horse Spleen Ferritin

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EXAFS and Near Edge Structure III

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 2))

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Abstract

Ferritin, a hollow, spherical protein encasing a polymeric core of hydrous ferric oxide and ferric oxyphosphate (8:1), stores iron in a soluble, bioavailable form for plants, animals, and some bacteria. The core has some properties in common with geochemical materials, e. g. ferrihydrate and oceanic, volcanogenic ferric oxides, but in ferritin, core formation (nucleation) and utilization appear to be influenced by the protein and by its interactions with iron and other metals such as zinc. Metal environments of solutions of a Zn(II), Fe(III)-protein complex and a model Fe(III)ATP complex (4:1) were examined by XANES and EXAFS to determine the effect of zinc and phosphorous on the iron environment.

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Author information

Authors and Affiliations

  1. Department of Biochemistry, North Carolina State University, Raleigh, NC, 27695-7622, USA

    E. C. Theil

  2. Department of Physics, North Carolina State University, Raleigh, NC, 27695-7622, USA

    D. E. Sayers, A. N. Mansour & F. J. Rennick

  3. Department of Chemistry, University of New Hampshire, Durham, NH, 03824, USA

    C. Thompson

Authors
  1. E. C. Theil
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  2. D. E. Sayers
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  3. A. N. Mansour
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  4. F. J. Rennick
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  5. C. Thompson
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Editor information

Editors and Affiliations

  1. Department of Chemistry, Stanford University, Stanford, CA, 94305, USA

    Keith O. Hodgson , Britt Hedman  & James E. Penner-Hahn ,  & 

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© 1984 Springer-Verlag Berlin Heidelberg

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Theil, E.C., Sayers, D.E., Mansour, A.N., Rennick, F.J., Thompson, C. (1984). EXAFS and XANES Studies of Fe and Zn in Horse Spleen Ferritin. In: Hodgson, K.O., Hedman, B., Penner-Hahn, J.E. (eds) EXAFS and Near Edge Structure III. Springer Proceedings in Physics, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46522-2_28

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  • DOI: https://doi.org/10.1007/978-3-642-46522-2_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46524-6

  • Online ISBN: 978-3-642-46522-2

  • eBook Packages: Springer Book Archive

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