Abstract
Micrococcin was isolated from a species of micrococcus (No. 7218 of the National Collection of Type Cultures, London, England) by Su (1948a, b). This strain of micrococcus was isolated from sewage and showed a resemblance to M. varians. The organism is a Gram-positive facultative anaerobe. Media were developed to produce 40–60 μg of micrococcin per ml of culture (Kelly et al., 1952). An identical antibiotic, later called micrococcin P, was isolated from Bacillus pumilus (No. 8738 of the National Collection of Industrial Bacteria, Aberdeen, Scotland) by Fuller (1955) (Abraham et al., 1956). The antibiotic was found to be inhibitory chiefly to Gram-positive microorganisms (Table 1). Sensitive strains readily become resistant to micrococcin as reported by Su (1948 b). Its inhibition of growth of Streptomyces (Table 1) perhaps deserves further study.
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References
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Pestka, S. (1975). Micrococcin and Micrococcin P. In: Corcoran, J.W., Hahn, F.E., Snell, J.F., Arora, K.L. (eds) Mechanism of Action of Antimicrobial and Antitumor Agents. Antibiotics, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46304-4_31
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DOI: https://doi.org/10.1007/978-3-642-46304-4_31
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