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The Erythromycins

  • Chapter
Mechanism of Action of Antimicrobial and Antitumor Agents

Part of the book series: Antibiotics ((ANTIBIOTICS,volume 3))

Abstract

Erythromycin is an antibiotic which inhibits the growth of many Gram- positive and some Gram-negative organisms and is especially successful against group A streptococcal, staphylococcal, and pneumococcal infections. The bacteriostatic action of erythromycin is a result of the antibiotic’s ability to selectively inhibit protein synthesis in the susceptible bacteria, but not in the host mammalian tissue.

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  1. Nancy L. Oleinick
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  1. Department of Biochemistry, The Medical and Dental Schools, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois, 60611, USA

    John W. Corcoran Ph.D.

  2. Department of the Army, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C., 20012, USA

    Fred E. Hahn Ph.D.

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Oleinick, N.L. (1975). The Erythromycins. In: Corcoran, J.W., Hahn, F.E., Snell, J.F., Arora, K.L. (eds) Mechanism of Action of Antimicrobial and Antitumor Agents. Antibiotics, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46304-4_26

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