Abstract
Over the past two years successful strategies have been developed for effectively dealing with a small number of experimental tumors in mice. These strategies have been arrived at rather empirically on the basis of a cellular approach to the tumor. The logical extension of these methods to other experimental tumors would seem to be only a matter of time. However, of more importance, it should be possible to use the approach, with appropriate modification, to optimize the treatment of human tumors. In effect we are suggesting that it may be possible that human tumors can be effectively treated with chemotherapeutic agents we now possess and that significantly improved results will follow the use of appropriate drugs at appropriate dosages, combinations, and correct timing. But what are the appropriate drugs, the appropriate dosages, and the proper combinations, and what is the correct timing?
Reprinted by permission of Cancer Res. 29, 2308–2310 (1969).
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Bruce, W.R., Lin, H. (1971). An Empirical Cellular Approach to the Improvement of Cancer Chemotherapy. In: Ultmann, J.E., Griem, M.L., Kirsten, W.H., Wissler, R.W. (eds) Current Concepts in the Management of Lymphoma and Leukemia. Recent Results in Cancer Research, vol 36. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46259-7_7
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DOI: https://doi.org/10.1007/978-3-642-46259-7_7
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