Abstract
It has been well established during the last 10–15 years that most (all?) experimentally induced animal tumors possess specific antigens against which an immunity can be demonstrated by in vivo and in vitro techniques (Old and Boyse1964; Sjögren 1965; Klein 1966; Hellström and Hellström, 1969 b, 1970 b).Evidence that human neoplasms are antigenic as well has been forthcoming more recently. Some of this evidence will be summarized here, primarily by providing references. No attempts will be made to go into details, since these are covered in two recent review articles (Hellström and Hellström 1969 b, 1970 b, c; Klein 1970; Gold 1970).
The studies of the authors referred to in this article have been supported by grants CA-10188 and CA-10189 from National Institutes of Health, by grant T-453 from American Cancer Society, and by contract NIH-69-2061 from National Institutes of Health to the University of Minnesota, subcontracted to us.
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Hellström, K.E., Hellström, I. (1971). Immunity to Human Tumor Antigens. In: Ultmann, J.E., Griem, M.L., Kirsten, W.H., Wissler, R.W. (eds) Current Concepts in the Management of Lymphoma and Leukemia. Recent Results in Cancer Research, vol 36. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46259-7_20
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DOI: https://doi.org/10.1007/978-3-642-46259-7_20
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