Abstract
There have been numerous studies of the morphology, physiology, and biochemistry of rat and human placenta (Bergsma, 1965; Villes, 1960). Most of these have been concerned with examining the placenta as an organ maintaining the overall nutrition of the developing fetus. The placenta itself, however, is a growing organ. Few studies have concerned themselves with placental growth per se, and even fewer with placental growth on a cellular level. This paper presents data demonstrating that the placenta grows in a manner quite similar to most other organs and that stimuli affecting fetal growth may also affect placental growth. Since placenta is readily available for study, abnormalities in fetal growth which are paralleled in the placenta could more easily be investigated using placenta. With this in mind, placental growth has been examined in the normal rat and human and under certain abnormal conditions known to affect the growth of the fetus. These include maternal diabetes, “placental insufficiency,” and maternal malnutrition.
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Winick, M. (1968). Cellular Growth of the Placenta as an Indicator of Abnormal Fetal Growth. In: Adamsons, K. (eds) Diagnosis and Treatment of Fetal Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46172-9_5
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DOI: https://doi.org/10.1007/978-3-642-46172-9_5
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