Skip to main content

The Influence of the Neurohypophysial Hormones and Similar Polypeptides on the Kidneys

  • Chapter

Abstract

Several aspects concerning the subject of the present section have been dealt with in a number of previous reviews (Berde, 1963; Dicker, 1961, 1964; Heller, 1951, 1955, 1957; Lipsett, Schwartz and Thorn, 1961; Nielsen, 1964; Pick-ford, 1966; Sawyer, 1961a, b,c, 1963, 1966; Schwartz and Livingston, 1964; Rudinger, 1964a,b; Thorn, 1958, 1960a; Thorp, 1962; Ussing et al, 1960).

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abbrecht, P. H., and R.L. Malvin: Flow rate of urine as a determinant of renal counter-current multiplier system. Amer. J. Physiol. 199, 919–922 (1960).

    CAS  PubMed  Google Scholar 

  • —: Effects of GFR and renal plasma flow on urine osmolarity. Amer. J. Physiol. 201, 754–758 (1961).

    CAS  PubMed  Google Scholar 

  • Abdttl-Karim, R., and N.S. Assali: Renal function in human pregnancy. V. Effects of oxy-tocin on renal hemodynamics and water and electrolyte excretion. J. Lab. clin. Med. 57, 522–532 (1961).

    Google Scholar 

  • Abrahams, C.V., and M. Pickford: The effect of 5-hydroxytryptamine on the urethra and on the blood pressure of dogs, and of adrenaline, noradrenaline and posterior pituitary extract on the urethra. Brit. J. Pharmacol. 11, 44–49 (1956).

    CAS  PubMed  Google Scholar 

  • Adamsons, K. Jr., S.L. Engel, and H.B. Van Dyke: The stability of natural and synthetic neurohypophysial hormones in vitro. Endocrinology 63, 679–681 (1958).

    Article  CAS  PubMed  Google Scholar 

  • Ahmed, A.B. J., B.C. George, C. Gonzales-Auvert, and J.F. Dingman: Increased plasma arginine vasopressin in clinical adrenocortical insufficiency and its inhibition by gluco-steroids. J. clin. Invest. 46, 111–123 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Aikawa, J.K., and J.P. Pilliod: Changes in renal tissue composition induced in rabbits by various intravenous doses of mercaptomerin sodium. Proc. Soc. exp. Biol. (N.Y.) 101, 61–66 (1959).

    CAS  Google Scholar 

  • Albers, R.W., and M.W. Brightman: A major component of neurohypophysial tissue associated with antidiuretic activity. J. Neurochem. 3, 269–276 (1959).

    Article  CAS  PubMed  Google Scholar 

  • Albright, F., and F.C. Bartter: The effects of anterior pituitary adrenocorticotropic hormone (ACTH) on bone metabolism. Transactions of the 2nd Conf. on Metabolic Interrelations. New York: J. Macy Found. 1950.

    Google Scholar 

  • Alexander, C.: The effect of 3′,5′-cyclic AMP and other nucleotides on urine flow and hemodynamics in the rat. J. clin. Invest. 44, 1025 (1965).

    Article  Google Scholar 

  • Alexander, C.S.: Production of diabetes insipidus in the rat. Proc. Soc. exp. Biol. (N.Y.) 99, 142–146 (1958).

    CAS  Google Scholar 

  • —, and D.M. Filbin: Failure of vasopressin to produce normal urine concentration in patients with diabetes insipidus. J. Lab. clin. Med. 54, 566–571 (1959).

    CAS  PubMed  Google Scholar 

  • Ali, M. N.: A comparison of some activities of arginine vasopressin and lysine vasopressin on kidney function in conscious dogs. Brit. J. Pharmacol. 13, 131–137 (1958).

    CAS  PubMed  Google Scholar 

  • —, R. B. Cross, and M. Pickford: Electrolyte excretion in diuretic and non-diuretic dogs. J. Physiol. (Lond.) 41, 177–182 (1958).

    Google Scholar 

  • Ames, R.G., D.H. Moore, and H.B. Van Dyke: The excretion of posterior pituitary anti-diuretic hormone in the urine and its detection in the blood. Endocrinology 46, 215–227 (1950).

    Article  CAS  Google Scholar 

  • Anderson, W.A., and E. Brown: The influence of arginine vasopressin on the production of adenosine 3′,5′-monophosphate by adenyl cyclase from the kidney. Biochim. biophys. Acta (Amst.) 67, 674–676 (1963).

    Article  CAS  Google Scholar 

  • Andersson, B., and N. Persson: Intravenous assay of antidiuretic hormone using the goat. Acta physiol. scand. 42, 257–261 (1958).

    Article  CAS  PubMed  Google Scholar 

  • Angervall, L., L. Lehmann, and U. Bengtsson: The renal concentrating capacity in albino rats after long-term consumption of phenacetin, napa and acetylsalicylic acid. Acta med. scand. 175, 155–160 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Anselmino, K.J., F. Hoffmann, and W.P. Kennedy: The relation of hyperfunction of the posterior lobe of the hypophysis to ecclampsia and nephropathy of pregnancy. Edinb. med. J. 39, 376–388 (1932).

    Google Scholar 

  • Anslow, W.P., and L.G. Wesson Jr.: Some effects of pressor-antidiuretic and oxytocic fractions of posterior pituitary extract on sodium, chloride, potassium and ammonium excretion in the dog. Amer. J. Physiol. 182, 561–566 (1955).

    CAS  PubMed  Google Scholar 

  • Appelboom, J.W., W.A. Brodsky, and W.N. Scott: Effect of osmotic diuresis on intrarenal solutes in diabetes indipidus and hydropenia. Amer. J. Physiol. 208, 38–45 (1965).

    CAS  PubMed  Google Scholar 

  • Ashman, D.F., R. Lipton, M. Melicow, and T.D. Proce: Isolation of adenosine 3′,5′-mono-phosphate and guanosine 3’,5’-monophosphate from rat urine. Biochem. biophys. Res. Com. 11, 330 (1963).

    Article  CAS  PubMed  Google Scholar 

  • Assali, N.S., W. J. Dignam, and L. Longo: Renal function in human pregnancy. III. Effects of antidiuretic hormone (ADH) on renal hemodynamics and water and electrolyte excretion near term and post partum. J. clin. Endocr. 20, 581–592 (1960).

    Article  CAS  PubMed  Google Scholar 

  • Atherton, J.C., M.A. Hai, and S. Thomas: Transient saluresis due to lysine-vasopressin administration in the conscious water diuretic rat. J. Physiol. (Lond.) 190, 30–31 P (1967).

    Google Scholar 

  • Au, W.Y.W., and L.G. Raisz: Studies on the renal concentrating mechanism. V. Effect of diuretic agents. J. clin. Invest. 39, 1302–1311 (1960).

    Article  CAS  PubMed  Google Scholar 

  • Aukland, K.: Studies of renal circulation with inert gas. Measurements in tissue. Proc. 3rd Congr. Nephrol. Washington 1966.

    Google Scholar 

  • —, and R.W. Berliner: Renal medullary countercurrent system studied with hydrogen gas. Circulat. Res. 15, 430–442 (1962).

    Article  Google Scholar 

  • —, and J. Kjekshus: Tubular salt and water transport in hydrated dogs studied with push-flow technique. Amer. J. Physiol. 210, 971–979 (1966).

    CAS  PubMed  Google Scholar 

  • Baer, J.E., A.V. Brooks, R.M. Noll, and K.B. Beyer: Effect of hydrochlorothiazide on renal electrolyte gradient in glucose diuresis and experimental diabetes insipidus. J. Pharmacol, exp. Ther. 137, 319–323 (1962).

    CAS  Google Scholar 

  • Bahlmann, J., J.G. Giebisch, B. Ochwadt, and W. Schoeppe: Micropuncture study of isolated perfused rat kidney. Amer. J. Physiol. 212, 77–82 (1967).

    CAS  PubMed  Google Scholar 

  • Baker, G.P., H. Levitin, and F.H. Epstein: Sodium depletion and renal conservation of water. J. clin. Invest. 40, 867–873 (1961).

    Article  CAS  PubMed  Google Scholar 

  • Bank, N., and H.S. Aynedjian: A micropuncture study of the renal concentrating defect of potassium depletion. Amer. J. Physiol. 206, 1347–1354 (1964).

    CAS  PubMed  Google Scholar 

  • Baratz, R. A., A. Doig, and I. J. Adatto: Plasma antidiuretic activity and free water clearance following osmoreceptor and neurohypophyseal stimulation in human subjects. J. clin. Invest. 39, 1539–1545 (1960).

    Article  CAS  PubMed  Google Scholar 

  • —, and R. C. Ingraham: Sensitive bioassay method for measuring antidiuretic hormone in mammalian plasma. Proc. Soc. exp. Biol. (N.Y.) 100, 296–299 (1959).

    CAS  Google Scholar 

  • Barclay, J.A., R.F. Crampton, and D.M. Matthews: Henle’s loop and the sodium content of the medullae of mammalian kidneys. J. Physiol. (Lond.) 147, 48 P (1959).

    Google Scholar 

  • Barer, G. R.: The action of vasopressin, a vasopressin analogue (PLV2) oxytocin, angiotensin, bradykinin and theophylline ethylene diamine on renal blood flow in the anaesthetized cat. J. Physiol. (Lond.) 169, 62–72 (1963).

    CAS  Google Scholar 

  • Barger, A.C., R.D. Berlin, and J.F. Tulenko: Infusion of aldosterone, 9-fluorohydrocorti-sone and antidiuretic hormone into the renal artery of normal and adrenalectomized, Tin-anesthetized dogs. Effect on electrolyte and water excretion. Endocrinology 62, 804–815 (1958).

    Article  CAS  PubMed  Google Scholar 

  • Barltrop, D.: Diabetes insipidus treated with synthetic lysine vasopressin. Lancet 1963, 176-278.

    Google Scholar 

  • Barnafi, L., R. Rosas, M. De la Lastra, and H. Croxatto: Influence of oxytocin and vasopressin on sodium-retaining activity of aldosterone in the rat. Amer. J. Physiol. 198, 255–259 (1960).

    CAS  PubMed  Google Scholar 

  • —, T. Pereda, and H. Croxatto: Effect of vasopressin structural modifications on rat renal excretion of Na, K and water. Amer. J. Physiol. 202, 593–596 (1962).

    CAS  PubMed  Google Scholar 

  • Barnett, H.L., C.W. Forman, and H.D. Lauson: The nephrotic syndrome in children. Advanc. Pediat. 5, 53–128 (1952).

    CAS  Google Scholar 

  • Barth, T., W. Pliska, and I. Rychlik: Chymotryptic and tryptic cleavage of oxytocin and vasopressin. Collection Czech. Chem. Commun. 32, 1058–1063 (1967).

    Article  CAS  Google Scholar 

  • Bartter, F. C., and W. B. Schwartz: The syndrome of inappropriate secretion of antidiuretic hormone. Amer. J. Med. 42, 790–806 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Battman, J.W.: Effect of hypophysectomy on the renal concentrating ability of the rat. Endocrinology 77, 496–500 (1965).

    Article  Google Scholar 

  • —, C. Guyot-Jeannin, and J. Dobrowolski: Nutritional state and urine concentrating ability in the rat. J. Endocrin. 30, 147–148 (1964).

    Article  Google Scholar 

  • Bentley, P.J.: The effects of neurohypophyseal extracts on water transfer across the wall of the isolated urine bladder of the toad, bufo marinus. J. Endocr. 17, 201–209 (1958).

    Article  CAS  PubMed  Google Scholar 

  • —: The effects of ionic changes on water transfer across the isolated urinary bladder of the toad bufo marinus. J. Endocr. 18, 327–333 (1959).

    Article  CAS  Google Scholar 

  • — Neurohypophysial function in amphibians, reptiles and birds. Symp. Zool. Soc. London 9, 141–152 (1963).

    Google Scholar 

  • Beránková-Ksandrová, Z., G.W. Bisset, K. Jost, I. Krejci, V. Pliska, J. Rttdinger, I. Rychltk, and F. Sorm: Synthetic analogues of oxytocin acting as hormonogens. Brit. J. Pharmacol. 26, 615–632 (1966).

    PubMed  Google Scholar 

  • Berde, B.: Pharmacologie des hormones neurohypophysaires. Paris: Masson & Cie 1963.

    Google Scholar 

  • —: Les analogues synthetique des hormones neurohypophysaires sont-ils une clef de l’étude des troubles de l’hormonogenese de ce systeme? Rapport de la VIIIe reunion des endocrinologistes de langue française, p. 33-49 (1965).

    Google Scholar 

  • —, and R. A. Boissonnas: Synthetic analogues and homologues of the posterior pituitary gland. In: The pituitary gland. Ed. by G. W. Harris and B.T. Donovan. London: Butter-worths 1966.

    Google Scholar 

  • —, u. A. Cerletti: Über die antidiuretische Wirkung von synthetischem Lysin-Vasopressin. Helv. physiol. pharmacol. Acta 19, 135–150 (1961).

    CAS  Google Scholar 

  • —: Medizinische und biologische Aspekte von pharmakologischen Arbeiten mit synthetischen Peptiden von neurohypophysärem Typus. Klin. Wschr. 42, 1159–1165 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —, W. Doepfner, and H. Konzett: Some pharmacological actions of four synthetic analogues of oxytocin. Brit. J. Pharmacol. 12, 209–214 (1957).

    CAS  PubMed  Google Scholar 

  • —, u. A. Cerletti: Über Phenylalanin2-Lysin-Vasopressin. Helv. physiol. pharmacol. Acta 19, 285–302 (1961).

    CAS  PubMed  Google Scholar 

  • Berliner, R.W., and C.M. Bennett: Concentration of urine in the mammalian kidney. Amer. J. Med. 42, 777–789 (1967).

    Article  CAS  PubMed  Google Scholar 

  • —, and D. G. Davidson: Production of hypertonic urine in the absence of pituitary anti-diuretic hormone. J. clin. Invest. 36, 1416–1427 (1957).

    Article  CAS  PubMed  Google Scholar 

  • —, N. Levinsky, D. G. Davidson, and M. Eden: Dilution and concentration of the urine and the action of antidiuretic hormone. Amer. J. Med. 24, 730–744 (1958).

    Article  CAS  PubMed  Google Scholar 

  • Berlyne, G.M., and A. Macken: On the mechanism of renal inability to produce a concentrated urine in chronic hydronephrosis. Clin. Sci. 22, 315–324 (1962).

    CAS  PubMed  Google Scholar 

  • —, S. Nilwarangkur, K. Janabi, and M. Cooper: Nocturnal nephrogenic diabetes insipidus. Quart. J. Med. 34, 463–479 (1965).

    CAS  PubMed  Google Scholar 

  • Bickford, R.G., and F.R. Winton: The influence of temperature on the isolated kidney of the dog. J. Physiol. (Lond.) 89, 198–219 (1937).

    CAS  Google Scholar 

  • Binkley, F., and G.M. Christensen: An effect of vasopressin on renal weight. Endocrinology 64, 307–308 (1959).

    Article  CAS  PubMed  Google Scholar 

  • Birnie, J.H., W.J. Eversole, W.R. Boss, CM. Osborn, and R. Gaunt: An antidiuretic substance in the blood of normal and adrenalectomized rats. Endocrinology 47,1–12 (1950).

    Article  CAS  PubMed  Google Scholar 

  • Bisset, G.W.: Effect of tyrosinase preparations on oxytocin, vasopressin and bradykinin. Brit. J. Pharmacol. 18, 405–420 (1962).

    CAS  PubMed  Google Scholar 

  • Black, D.A.K.: Renal rete mirabile. Lancet 1965, 1141-1152.

    Google Scholar 

  • —, and A. E. Thomson: Day-to-day changes in sodium and water output with and without posterior pituitary extract. Clin Sci. 10, 511–520 (1951).

    Google Scholar 

  • Boba, A., and S.R. Powers: Mannitol-vasopressin in the splenectomized dog. J. surg. Res. 6, 265–273 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Bocanegra, M., and H.D. Lauson: Ultrafilterability of endogenous antidiuretic hormone from plasma of dogs. Amer. J. Physiol. 200, 486–493 (1961).

    CAS  Google Scholar 

  • Boissonnas, R. A., St. Guttman, B. Berde, and H. Konzett: Relationship between the chemical structures and the biological properties of the posterior pituitary hormones and their synthetic analogues. Experientia (Basel) 17, 377–391 (1961).

    Article  CAS  Google Scholar 

  • Bojesen, E.: Den tubulaere saltvandsresorption. Kobenhavn: Christtreus 1955.

    Google Scholar 

  • Boss, J.M.N., H. Dlouha, M. Kraus, and J. Krecek: The development of the kidney in young rats. J. Physiol. (Lond.) 161, 51-52 P (1962).

    Google Scholar 

  • Boura, A., and S. E. Dicker: An apparatus for the maintenance of a constant water load and the recording of urine flow in rats. J. Physiol. (Lond.) 122, 144–148 (1953).

    CAS  Google Scholar 

  • Bower, B.F., and G.S. Gordon: Hormonal effects of nonendocrine tumors. Ann. Rev. Med. 16, 83–118 (1965).

    Article  CAS  PubMed  Google Scholar 

  • —, D. M. Mason, and P. H. Forsham: Bronchogenic carcinoma with inappropriate antidiuretic activity in plasma and tumor. New Engl. J. Med. 271, 934–938 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Boylan, J. W., and E. Asshatjer: Depletion and restoration of the medullary osmotic gradient in the dog kidney. Pflügers Arch. ges. Physiol. 276, 99–116 (1962).

    Article  CAS  Google Scholar 

  • Bozler, E.: Osmotic effects and diffusion of nonelectrolytes in muscle. Amer. J. Physiol. 197, 505–510 (1959).

    CAS  PubMed  Google Scholar 

  • Branda, L. A., and V. Du Vigneaud: Synthesis and pharmacological properties of 9-decar-boxamido-oxytocin. J. med. pharm. Chem. 9, 169–172 (1966).

    Article  CAS  Google Scholar 

  • Bray, G.A.: Distribution of urea, thiourea-C14 and sucrose-C14 in dog kidney during anti-diuresis. Amer. J. Physiol. 199, 1211–1214 (1960).

    CAS  Google Scholar 

  • —: Freezing point depression of rat kidney slices during water diuresis and antidiuresis. Amer. J. Physiol. 199, 915–918 (1960).

    CAS  Google Scholar 

  • Brodehl, J.A., K. Gellissen, u. W. Hagge: Die Wirkung des Vasopressins beim Diabetes Insipidus Renalis. Klin. Wschr. 43, 72–78 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Brook, A.H., and L. Share: On the question of protein binding and the diffusibility of circulating antidiuretic hormone in the dog. Endocrinology 78, 779–785 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Brooks, F.P., and M. Pickford: The effect of posterior pituitary hormones on the excretion of electrolytes in dogs. J. Physiol. (Lond.) 142, 468–493 (1958).

    CAS  Google Scholar 

  • Brown, E., D.L. Clarke, V. Roux, and G.H. Sherman: The stimulation of adenosine 3′,5′-monophosphate production by antidiuretic factors. J. biol. Chem. 238, PC852–PC853 (1963).

    Google Scholar 

  • Brown, J.H.U., and A.A. Petkas: The behavior of kidney mitochondria under the influence of ADH. Endocrinology 69, 182–183 (1961).

    Article  CAS  Google Scholar 

  • Brun, C., E.O.E. Knudsen, and F. Raaschou: On the cause of postsyncopal oliguria. Acta med. scand. 122, 486–500 (1945).

    Article  CAS  PubMed  Google Scholar 

  • Brunner, F.P., and D.W. Seldin: The mechanism of the urinary concentrating defect in potassium dificient rats. Pflügers Arch. ges. Physiol. 290, 202–210 (1966).

    Article  CAS  Google Scholar 

  • Brunner, H., G. Kuschinsky, O. Münchow, u. G. Peters: Der Einfluß von Oxytocin auf Diurese und Salzausscheidung bei Ratte und Mensch. Klin. Wschr. 34, 451–452 (1956).

    Article  CAS  PubMed  Google Scholar 

  • Buchborn, E.: Ein quantitativer biologischer Adiuretin-(Vasopressin-)Nachweis an der Kröte. Z. ges. exp. Med. 125, 614–625 (1955).

    Article  CAS  PubMed  Google Scholar 

  • —: Klinische Pathophysiologie der Harnkonzentrierung. Schweiz, med. Wschr. 94, 1273–1283 (1964).

    CAS  Google Scholar 

  • Bucher, O. Von, u. PH. Grand Jean: Zur Frage der Angriffspunkte des antidiuretischen Hormons in der Niere. Z. Biol. 113, 67–76 (1961).

    CAS  PubMed  Google Scholar 

  • Buckalew, V.M., M.A. Ramirez, and M. Goldberg: Free water reabsorption during solute diuresis in normal and potassium depleted rats. Amer. J. Physiol. 212, 381–386 (1967).

    CAS  PubMed  Google Scholar 

  • Bulger, R.E., L.D. Griffith, and B.F. Trump: Endoplasmic reticulum in rat renal interstitial cells. Molecular rearrangement after water deprivation. Science 151, 83–86 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Burn, H.: Estimation of the antidiuretic potency of pituitary (posterior lobe) extract. Quart. J. exp. Biol. (N.Y.) 4, 517–529 (1931).

    CAS  Google Scholar 

  • Capek, K., G. Fuchs, G. Rumrich, u. K.J. Ullrich: Harnstoffpermeabilität der corticalen Tubulusabschnitte von Ratten in Antidiurese und Wasserdiurese. Pflügers Arch. ges. Physiol. 290, 237–249 (1966).

    Article  CAS  Google Scholar 

  • Carasso, N., P. Favard, J. Bourguet, et S. Jard: Role du flux net d’eau dans les modifications ultrastructurales de la vessie de grenouille stimulée par l’oxytocine. J. Microsc. 5, 519–522 (1966).

    CAS  Google Scholar 

  • —, and J. Valerien: Variations des ultrastructure dans les cellules epitheliales de la vessie du crapaud apres stimulation par l’hormone neurohypophysaires. J. Microscopie 1,143–158 (1962).

    Google Scholar 

  • Carone, F. A., and F.H. Epstein: Nephrogenic diabetes insipidus caused by amyloid disease. Amer. J. Med. 29, 539–544 (1960).

    Article  CAS  PubMed  Google Scholar 

  • —, B. A. Everett, N. J. Blondeel, and M. Goldberg: Renal localization of albumin and its function in the concentrating mechanism. Amer. J. Physiol. 212, 387 (1967-393).

    CAS  PubMed  Google Scholar 

  • Chabria, N.L., and B.B. Gaitonde: Effect of dexamethasone on urine output and electrolyte excretion in rats. Arch. int. Pharmacodyn. 162, 364–370 (1966).

    CAS  PubMed  Google Scholar 

  • Chalmers, T. M., A. A. G. Lewis, and G. L. S. Pawan: The effect of posterior pituitary extracts on the renal excretion of sodium and chloride in man. J. Physiol. (Lond.) 112, 238–242 (1951).

    CAS  Google Scholar 

  • Chan, W. Y.: Effects of neurohypophysial hormones and their deamino analogues on renal excretion of Na, K and water in rats. Endocrinology 77, 1097–1104 (1965).

    Article  CAS  PubMed  Google Scholar 

  • —, and H. Sawyer: Saluretic actions of neurohypophysial peptides in conscious dogs. Amer. J. Physiol. 201, 799–803 (1961).

    CAS  PubMed  Google Scholar 

  • —, and W.H. Sawyer: Natriuresis in conscious dogs during arginine vasopressin infusion and after oxytocin injection. Proc. Soc. exp. Biol. (N.Y.) 110, 697–699 (1962).

    CAS  Google Scholar 

  • Chaudhury, R.R., and J.M. Walker: The fate of injected oxytocin in the rabbit. J. Endocr. 19, 189–192 (1959).

    Article  CAS  PubMed  Google Scholar 

  • Chinard, F.P.: Kidney, water and electrolytes. Ann. Rev. Physiol. 26, 187–226 (1964).

    Article  CAS  Google Scholar 

  • Clapp, J. R.: Renal tubular reabsorption of urea in normal and protein-depleted rats. Amer. J. Physiol. 210, 1304–1308 (1966).

    CAS  PubMed  Google Scholar 

  • —, and R.R. Robinson: Osmolality of distal tubular fluid in the dog. J. clin. Invest. 45, 1847–1853 (1966).

    Article  CAS  PubMed  Google Scholar 

  • —, J. F. Watson, and R. W. Berliner: Osmolality, bicarbonate concentration and water reabsorption in proximal tubule of the dog nephron. Amer. J. Physiol. 205, 273–279 (1963).

    CAS  PubMed  Google Scholar 

  • Crabbé, J.: The role of aldosterone in the renal concentration mechanism in man. Clin. Sci. 23, 39–46 (1962).

    PubMed  Google Scholar 

  • —, and P. De Weer: Action of aldosterone and vasopressin on the active transport by the isolated toad bladder. J. Physiol. (Lond.) 180, 560–568 (1965).

    Google Scholar 

  • Cornil, A., J.C. Demant, P. Van Geel, et P.A. Bastenie: Syndrome de Schwartz Bartter au cours d’une porphyrie aigue intermittente. Acta clin. belg. 20, 286–299 (1965).

    CAS  PubMed  Google Scholar 

  • Cort, J.H., J. Rudinger, B. Lichardus, and J. Hagemann: Effects of oxytocin antagonists on the saluresis accompanying carotid occlusion. Amer. J. Physiol. 210, 162–168 (1966).

    CAS  PubMed  Google Scholar 

  • Crawford, R.F., A. Paresi, P. Meara, and M.L. Terry: Urine composition and renal tissue electrolytes. Amer. J. Dis. Child. 94, 512–513 (1957).

    Google Scholar 

  • —, and B. Pinkham: An assay method for antidiuretic hormone based on a more specific response index. Endocrinology 55, 521–529 (1954).

    Article  CAS  PubMed  Google Scholar 

  • Cross, B.A., and G.W. Harris: The role of the neurohypophysis in the milk-ejection reflex. J. Endocr. 8, 148–161 (1952).

    Article  CAS  PubMed  Google Scholar 

  • Cross, R.B.: The effects of osmotic diuresis and vasopressin upon the distribution of sodium, potassium and urea in the rat kidney. Aust. J. exp. Biol. med. Sci. 42, 523–538 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —, S.E. Dicker, A.H. Kitchin, S. Lloyd, and M. Pickford: The effect of oxytocin on urinary excretion of water and electrolytes in man. J. Physiol. (Lond.) 153, 553–561 (1960).

    CAS  Google Scholar 

  • —, E. Lee, and W.M. Thornton: The effect of vasopressin on urea excretion by the sheep. J. Physiol. (Lond.) 187, 34–35 (1966a).

    Google Scholar 

  • —, and L.A. Sherrington: The effect of vasopressin on water distribution in the rat kidney. Aust. J. exp. Biol. med. Sci. 43, 505–510 (1965).

    Article  CAS  PubMed  Google Scholar 

  • —, and W.M. Thornton: The effect of vasopressin upon the distribution of serum albumin in the rat kidney. Aust. J. exp. Biol. med. Sci. 44, 137–142 (1966b).

    Article  CAS  PubMed  Google Scholar 

  • —, W.M. Thornton, and E.D. Twedell: The effect of vasopressin on water and electrolyte excretion by the sheep. Aust. J. exp. Biol. med. Sei. 41, 629–636 (1963).

    Article  CAS  Google Scholar 

  • Croxatto, H., u. E. Labarca: Die Wirkung von synthetischem Oxytocin (Syntocinon) und Acetazolamid auf die Ausscheidung von Wasser, Natrium und Kalium. Experientia (Basel) 14, 339–341 (1958).

    Article  CAS  Google Scholar 

  • Curtis, J.R., and H.E. De Wardener: Effect of urine pH on the changes in urine concentration produced by vasopressin. Clin. Sei. 24, 159–166 (1963).

    CAS  Google Scholar 

  • Cutler, R.E., C.R. Kleemann, M.H. Maxwell, and J.T. Dowling: Physiologic studies in nephrogenic diabetes insipidus. J. clin. Endocr. 22, 827–838 (1962).

    Article  CAS  PubMed  Google Scholar 

  • Czaczkes, J. W., M. Eliakim, and T.D. Ullman: Diminished antidiuretic response to pitressin in diabetes insipidus during the infusion of sodium bicarbonate solution. J. Lab. clin. Med. 57, 938–945 (1961).

    CAS  PubMed  Google Scholar 

  • —, C. R. Kleeman, and M. Koenig: Physiologic studies of antidiuretic hormone by its direct measurement in human plasma. J. clin. Invest. 43, 1625–1640 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Dainty, J., and C.R. House: An examination of the evidence for membrane pores in frog skin. J. Physiol. (Lond.) 185, 172–241 (1966).

    CAS  Google Scholar 

  • Dale, H.: Evidence concerning the endocrine function of the neurohypophysis and its nervous control. In: The Neurohypophysis. Ed. by H. Heller. London: Butterworths 1957.

    Google Scholar 

  • Dalton, A.J., and F. Haguenau: Ultrastructure of the kidney. New York: Academic Press (1967).

    Google Scholar 

  • Daniel, J., u. F. Högler: Über die Diuresehemmung durch Pituitrinum infundibulare (in-fundibulin). Wien. Arch. inn. Med. 13, 481–508 (1927).

    CAS  Google Scholar 

  • Dantzler, W. H.: Renal response of chickens to infusion of hyperosmotic sodium chloride solution. Amer. J. Physiol. 210, 640–646 (1966).

    CAS  PubMed  Google Scholar 

  • Darmady, E.M., and J. Durant, E.R. Matthews, and F. Stranack: Location of 131J Pitres-sin in the kidney by autoradiography. Clin. Sci. 19, 229–241 (1960).

    CAS  PubMed  Google Scholar 

  • —, J. Offer, J. Prince, and F. Stanack: The proximal convoluted tubule in the renal handling of water. Lancet 1964, 1254-1257.

    Google Scholar 

  • Davey, M. J., and M.F. Lockett: Actions and interactions of aldosterone, monoacetate and neurohypophysial hormones on the isolated cat kidney. J. Physiol. (Lond.) 152, 206–219 (1960).

    CAS  Google Scholar 

  • David, M.A., u. K. Kovacs: Die Wirkung der Oestronbehandlung auf die antidiuretische Aktivität des Vasopressins. Endokrinologie 46, 217–223 (1964).

    CAS  PubMed  Google Scholar 

  • Davis, B.B., F.G. Knox and R.W. Berliner: The effect of vasopressin on proximal tubule sodium reabsorption in the dog. Amer. J. Physiol. 212, 1361–1364 (1967).

    CAS  PubMed  Google Scholar 

  • De Bodo, K.C., and K.F. Prescott: The antidiuretic action of barbiturates (phenobarbital, amytal, Pentobarbital) and the mechanism involved in this action. J. Pharmacol, exp. Ther. 85, 222–233 (1945).

    Google Scholar 

  • Deis, R.P., S. Lloyd, and M. Pickford: The effects of stilboestrol and progesterone and of renal denervation on the response of the kidney to vasopressin and oxytocin. J. Physiol. (Lond.) 165, 348–357 (1963).

    CAS  Google Scholar 

  • Del Greco, F., and H.E. De Wardener: The effect on urine osmolarity of a transient reduction in glomerular filtration rate and solute output during a water diuresis. J. Physiol. (Lond.) 131, 307–316 (1956).

    Google Scholar 

  • Demunbrun, T.W., A.D. Keller, A.H. Levkoff, and R.M. Pusser, Jr.: Pitocin restoration of renal hemodynamics to pre-neurohypophysectomy levels. Amer. J. Physiol. 179, 429–438 (1954).

    CAS  PubMed  Google Scholar 

  • Dettelbach, H. R.: A method for assaying small amounts of antidiuretic substances with notes on some properties of vasopressin. Amer. J. Physiol. 192, 379–386 (1958).

    CAS  PubMed  Google Scholar 

  • Deutsch, S., M. Goldberg, and R.D. Dripps: Postperative hyponatremia with the inappropriate release of antidiuretic hormone. Anesthesiology 27, 250–256 (1966).

    CAS  PubMed  Google Scholar 

  • De Wardener, H.E.: Polyuria. J. chron. Dis. 2, 199–212 (1960).

    Article  Google Scholar 

  • —, and A. Herxheimer: The effect of a high water intake on the kidney’s ability to concentrate the urine in man. J. Physiol. (Lond.) 139, 42–52 (1957).

    Google Scholar 

  • De Wied, D.: A simple automatic and sensitive method for the assay of antidiuretic hormone with notes on the antidiuretic potency of plasma under different experimental conditions. Acta physiol. pharmacol. neerl. 9, 69–81 (1960).

    PubMed  Google Scholar 

  • Diamond, J.M., and J. McD. Tormey: The role of long extracellular channels in fluid transport across epithelia. Nature (Lond.) 210, 817–820 (1966).

    Article  CAS  Google Scholar 

  • Dick, D.A.T.: Cell water. London: Butterworth 1966.

    Google Scholar 

  • Dicker, S.E.: A method for the assay of very small amounts of antidiuretic activity with a note on the antidiuretic titre of rat’s blood. J. Physiol. (Lond.) 122, 149–157 (1953).

    CAS  Google Scholar 

  • —: Release and metabolism of neurohypophyseal hormones. J. Pharm. Pharmacol. 13, 449–469 (1961).

    Article  CAS  PubMed  Google Scholar 

  • —: The mechanism of action of oxytocin and vasopressin and their analogues on the kidney of mammals. In: Oxytocin, vasopressin and structual analogues. Ed. by J. Rudinger. Perga-mon Press, Czech. Medical Press 1964.

    Google Scholar 

  • —, M.C. Eggleton, and J. Haslam: The effects of urea and hydrochlorothiazide on the renal functions of rat and domestic fowl. J. Physiol. (Lond.) 187, 247–255 (1966).

    CAS  Google Scholar 

  • —, and M. G. Eggleton: Renal excretion of hyaluronidase and calcium in man during the antidiuretic action of vasopressin and some analogues. J. Physiol. (Lond.) 157, 351–362 (1961).

    CAS  Google Scholar 

  • —, and C. S. Franklin: The isolation of hyaluronic acid and chondroitin sulphate from kidneys and their reaction with urinary hyaluronidase. J. Physiol. (Lond.) 186, 110–120 (1966).

    CAS  Google Scholar 

  • —, and A. L. Greenbaum: The destruction of the antidiuretic activity of vasopressin by-SH active compounds. J. Physiol. (Lond.) 141, 107–116 (1938).

    Google Scholar 

  • —, and J. Haslam: Water diuresis in the domestic fowl. J. Physiol. (Lond.) 183, 225–235 (1966).

    CAS  Google Scholar 

  • —, and H. Heller: The renal action of posterior pituitary extract and its fractions as analyzed by clearance experiments on rats. J. Physiol. (Lond.) 104, 353–360 (1946).

    CAS  Google Scholar 

  • —, and J. Nunn: Antidiuresis in adult and old rats. J. Physiol. (Lond.) 141, 332–336 (1958).

    CAS  Google Scholar 

  • Dingman, J. F.: Hypothalamus and the endocrine control of sodium and water metabolism in man. Amer. J. med. Sci. 235, 79–99 (1958).

    Article  CAS  PubMed  Google Scholar 

  • —, and J.H. Hauger-Klevene: Treatment of diabetes insipidus: synthetic vasopressin nasal solution. J. clin. Endocr. 24, 550–553 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Dlouha, H., J. Krecek, M. Kraus, and V. Pliska: Sensitivity of rats to vasopressin in the weaning period. Physiol. bohemoslov. 14, 217–224 (1965).

    CAS  PubMed  Google Scholar 

  • Douglas, C.P.: Oxytocin and antidiuresis in pregnancy at term. Clin. Sci. 28, 39–42 (1965).

    CAS  PubMed  Google Scholar 

  • Dow, J., and R.O.H. Irvine: The effect of diuretics on cortico-medullary gradients of sodium and urea in rat kidney. Nephron 4, 25–31 (1967).

    Article  CAS  Google Scholar 

  • Dyball, R.E. J., G. J. Lane, and R.G. Morris: A simplified automatic device for the performance of antidiuretic assays. J. Physiol. (Lond.) 186, 43P–44P (1966).

    CAS  Google Scholar 

  • Earle, D.P. Jr., R.C. De Bodo, I.L. Schwartz, S. J. Farber, M. Kurtz, and J. Greenberg: Effect of hypophysectomy on electrolyte and water metabolism in the dog. Proc. Soc. exp. Biol. (N.Y.) 76, 608–612 (1951).

    CAS  Google Scholar 

  • Edelmann, CM., H.L. Barnett, and H. Stark: Effect of urea on concentration of urinary nonurea solute in premature infants. J. appl. Physiol. 21, 1021–1025 (1966).

    CAS  PubMed  Google Scholar 

  • Epstein, F.H.: Disorders of renal concentrating ability. Yale J. Biol. Med. 39,186–190 (1966).

    CAS  PubMed  Google Scholar 

  • —, C.R. Kleeman, and A. Hendrlkx: The influence of bodily hydration on the renal concentrating process. J. clin. Invest. 36, 629–634 (1957).

    Article  CAS  PubMed  Google Scholar 

  • —, H. Levitin, G. Glaser, and P. Lavietes: Cerebral hyponatremia New. Engl. J. Med. 265, 513–518 (1961).

    Article  CAS  Google Scholar 

  • Ericsson, J. L.E.: Glutaraldehyd perfusion of the kidney for preservation of proximal tubules with patent lumens. J. Microscopie 5, 97–100 (1966).

    Google Scholar 

  • Ezrin, C., L. Loach, and T. F. Nicholson: Diuretic effect of oxytocin in a patient with reversed diurnal rhythm of water and electrolyte excretion. Canad. med. Ass. J. 87, 673–675 (1962).

    CAS  PubMed  Google Scholar 

  • Fang, H.S., H.M. Liu, and S.C. Wang: Liberation of antidiuretic hormone following hypo-thalamic stimulation in the dog. Amer. J. Physiol. 202, 212–216 (1962).

    CAS  PubMed  Google Scholar 

  • Finn, A.L., J.S. Handler, and J. Orloff: Relation between toad bladder potassium content and permeability response to vasopressin. Amer. J. Physiol. 210, 1279–1285 (1966).

    CAS  PubMed  Google Scholar 

  • Fisher, C., W.R. Ingram, and S.W. Ranson: Diabetes insipidus and the vaso-humoral control of water balance. Ann. Arbor. J.W. Edwards (1938).

    Google Scholar 

  • Foëx, P., and O. Koralnik: Sécrétion inadéquate d’hormone antidiuretique lors d’une intoxication digitalique massive. Schweiz. med. Wschr. 96, 1750–1751 (1966).

    PubMed  Google Scholar 

  • Forsling, M.L., J. J. Jones, and J. Lee: A change of sensitivity to neurohypophysial hormones induced by their intravenous infusion in the rat. J. Physiol (Lond.) 191, 127P (1967).

    Google Scholar 

  • Forster, R.P.: Kidney, water and electrolytes. Ann. Rev. Physiol. 27, 183–232 (1965).

    Article  CAS  Google Scholar 

  • Foulkes, E. C.: The action of pitressin on solute permeability of the rabbit nephron in vivo. J. gen. Physiol. 50, 1–8 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Fourmann, J., and G.C. Kennedy: An effect of antidiuretic hormone on the flow of blood through the vasa recta of the rat kidney. J. Endocr. 35, 173–176 (1966).

    Article  Google Scholar 

  • —, and D.B. Moffat: The effect of water intake on the efferent arterioles of the juxtame-dullary glomeruli. 2nd Int. Congr. Nephrology Prague 1963. Excerpta med. Int. Congr. Series 78, 627-629.

    Google Scholar 

  • Frandsen, P.: The specific pressor and antidiuretic activity in rat urine after infusion of lysine-vasopressin. Acta pharmacol. (Kbh.) 25, 197–200 (1967).

    Article  CAS  Google Scholar 

  • —, and AA. Theil Nielsen: The antidiuretic effect of 5-hydroxytryptamine in the rat after subcutaneous injection of “physiological doses”. Acta pharmacol. (Kbh.) 24, 50–54 (1966).

    Article  CAS  Google Scholar 

  • Fraser, A. M.: The diuretic action of the oxytocic hormone of the pituitary and its effect on the assay of pituitary extracts. J. Pharmacol, exp. Ther. 60, 89–95 (1937).

    CAS  Google Scholar 

  • —: The action of the oxytocic hormone of the pituitary gland on urine secretion. J. Physiol. (Lond.) 101, 236–251 (1942).

    CAS  Google Scholar 

  • Frey, J., L. Kerp, u. W. Reichardt: Antidiurese und Zunahme der Harnkonzentration nach i. v. Vasopressin-Gabe beim Menschen. Pflügers Arch. ges. Physiol. 272, 80–81 (1960).

    Article  Google Scholar 

  • Friedler, R.M., and L.E. Earley: Reduced renal concentrating capacity during isotonic saline loading. Proc. Soc. exp. Biol. (N.Y.) 121, 352–357 (1966).

    CAS  Google Scholar 

  • Fugo, N.W., and G.T. Aragon: The utilization of an old technique for a sensitive antidiuretic assay. Fed. Proc. 6, 330–331 (1947).

    CAS  PubMed  Google Scholar 

  • Fukuda, T. R.: Tonic antagonism in the water permeability of sea urchin eggs. J. cell. comp. Physiol. 7, 301–311 (1936).

    Article  Google Scholar 

  • Galton, V. A., H. Valtin, and D. G. Johnson: Thyroid function in the absence of vasopressin. Endocrinology 78, 1224–1228 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Gans, J.H.: Vasopressin-induced saluresis in sheep. Amer. J. vet. Res. 25, 918–923 (1964).

    CAS  PubMed  Google Scholar 

  • Gardner, B., G.S. Gordan, and J. Witt: Urinary calcium excretion of women with breast cancer during post-hypophysectomy polyuria, spontaneous interphase and vasopressin-induced antidiuresis. Proc. Soc. exp. Biol. (N.Y.) 109, 71–75 (1962).

    CAS  Google Scholar 

  • Gardner, K.D., and R.H. Maffly: An in vitro demonstration of increased collecting tubular permeability to urea in the presence of vasopressin. J. clin. Invest. 43, 1968–1975 (1964).

    Article  PubMed  Google Scholar 

  • Gardner, K.D. Jr.: Dry weight as a point of reference in studies of renal papillary composition. Amer. J. Physiol. 211, 1031–1035 (1966).

    PubMed  Google Scholar 

  • Gauer, O.H., and P.S. Tata: Vasopressin studies in the rat. II. The amount of water reab-sorbed by the rat kidney after single i. v. injection of vasopressin: The vasopressin water equivalent. Pflügers Arch. Physiol. 290, 286–293 (1966).

    Article  CAS  Google Scholar 

  • Gaunt, R., C.W. Lloyd, and J.J. Chart: The adrenal-neurohypophysial interrelationship. In: The Neurohypophysis, p. 233. Ed. by H. Heller. London: Butterworths 1957.

    Google Scholar 

  • Gertz, K.H., G.C. Kennedy u. K.J. Ullrich: Mikropunktionsuntersuchungen über die Flüssigkeitsruckresorption aus den einzelnen Tubulusabschnitten bei Wasserdiurese (diabetes insipidus). Pflügers Arch. ges. Physiol. 278, 513–519 (1964).

    CAS  Google Scholar 

  • Gibbs, O.S.: A practical test for the antidiuretic action of pituitary. J. Pharmacol, exp. Ther. 40, 129–137 (1930).

    CAS  Google Scholar 

  • Giebisch, G.: Kidney, water and electrolyte metabolism. Ann. Rev. Physiol. 24, 357–420 (1962).

    Article  CAS  Google Scholar 

  • Gill, J. R., Jr., and F. C. Barter: On the impairment of renal concentrating ability in prolonged hypercalcemia and hypercalciuria in man. J. clin. Invest. 40, 716–722 (1961).

    Article  CAS  PubMed  Google Scholar 

  • Gilman, A., and L. Goodman: The secretory response of the posterior pituitary to the need for water conservation. J. Physiol. (Lond.) 90, 113–124 (1937).

    CAS  Google Scholar 

  • Ginetzinsky, A. G.: Role of hyaluronidase in the re-absorption of water in renal tubulus. The mechanism of action of the antidiuretic hormone. Nature (Lond.) 182, 1218–1219 (1958).

    Article  CAS  Google Scholar 

  • Ginsburg, M., and H. Heller: The antidiuretic assay of vasopressin by intravenous injection into unanaesthetized rats. J. Endocr. 9, 267–273 (1953).

    Article  CAS  PubMed  Google Scholar 

  • Glatte, H., R.E. Cutler, and J.T. Dowling: Studies of the renal concentrating defect in thyrotoxicosis. J. clin. Invest. 44, 1050 (1965).

    Google Scholar 

  • Glaubach, S., u. H. Molitor: Vergleich der Auswertungsmethoden von Gesamtextrakten des Hypophysenhinterlappens am isolierten Meerschweinchenuterus und an der Diuresehem-mung von Hunden, Ratten und Mäusen. Arch. exp. Pathol. Pharmakol. 166, 243–264 (1932).

    Article  CAS  Google Scholar 

  • Glimstedt, G., N. Jousson, and H.R. Rossman: The collecting tubules of the kidney in the rat at water overloading. Kungl. Fysiogr. Sällsk i Lunds Forh. 24, 1–9 (1954).

    Google Scholar 

  • Gloor, F., u. L.A. Neiditsch-Halff: Die interstitiellen Zellen des Nierenmarkes der Ratte. Z. Zellforsch. 66, 488–495 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Goldberg, M.: Hyponatremia and the inappropriate secretion of antidiuretic hormone. Amer. J. Med. 35, 293–298 (1963).

    Article  CAS  PubMed  Google Scholar 

  • Goldblatt, E.L., M.L. Kauker, R.S. Hare, and K. Hare: Effects of ethyleneimine on renal action of vasopressin. Proc. Soc. exp. Biol. (N.Y.) 123, 845–847 (1967).

    Google Scholar 

  • Goodman, B., A. Cohen, M.F. Lewitt, and M. Kahn: Renal concentration in the normal dog. Effect of an acute reduction in salt excretion. Amer. J. Physiol. 206, 1123–1128 (1964).

    CAS  PubMed  Google Scholar 

  • Goodmann, A., and H. Levitin: Effect of urinary pH on the renal concentrating mechanism. Amer. J. Physiol. 208, 847–851 (1965).

    Google Scholar 

  • Goodmann, R.: Diabetes insipidus. A two-year study with lysine8-vasopressin. Curr. ther. Res. 8, 56–60 (1966).

    Google Scholar 

  • Gottschalk, C.W.: Osmotic concentration and dilution of the urine. Amer. J. Med. 36, 670–685 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —, W.E. Lassiter, M. Mylle, K.J. Ullrich, B. Schmidt-Nielsen, R. O’dell, and G. Pehling: Micropuncture study of composition of loop of Henle fluid in desert rodents. Amer. J. Physiol. 204, 532–535 (1963).

    CAS  PubMed  Google Scholar 

  • —, F. Morel, and M. Mylle: Tracer microinjection studies of renal tubular permeability. Amer. J. Physiol. 209, 173–178 (1965).

    CAS  PubMed  Google Scholar 

  • —, and M. Mylle: Micropuncture study of pressures in proximal tubules and peritubular capillaries of the rat kidney and their relation to ureteral and renal venous pressures. Amer. J. Physiol. 185, 430–439 (1956).

    CAS  PubMed  Google Scholar 

  • —: Micropuncture study of pressures in proximal and distal tubules and peritubular capillaries of the rat kidney during osmotic diuresis. Amer. J. Physiol. 189, 323–328 (1957).

    CAS  PubMed  Google Scholar 

  • —: Micropuncture study of the mammalian urinary concentrating mechanism. Evidence for the countercurrent hypothesis. Amer. J. Physiol. 196, 927–936 (1959).

    CAS  PubMed  Google Scholar 

  • —, N.F. Jones, R.W. Winters, and L.G. Welt: Osmolality of renal tubular fluids in potassium-depleted rodents. Clin. Sci. 29, 249–260 (1965).

    CAS  PubMed  Google Scholar 

  • Granberg, P.-O.: Effect of acute hypoxia on renal haemodynamics and water diuresis in man. Stockholm: Svenska Tryckeriaktiebolaget 1963.

    Google Scholar 

  • Grantham, J. J., and M.B. Burg: Effect of vasopressin and cyclic AMP on permeability of isolated collecting tubules. Amer. J. Physiol. 211, 255–259 (1966).

    CAS  PubMed  Google Scholar 

  • Graser, F.: Die Beeinflussung der Chlorurese durch Oxytocin und Vasopressin beim diabetes insipidus. Klin. Wschr. 28, 551–552 (1950).

    Article  CAS  PubMed  Google Scholar 

  • Green, H.H., A.R. Harrington, and H. Valtin: Impaired water diuresis in rats with hereditary hypothalamic diabetes insipidus (DI) after adrenalectomy. 3rd Int. Congr. Nephro-logy, Washington, D.C., Abstr. II, p. 202 (1966).

    Google Scholar 

  • Greenbaum, A.L., and S.E. Dicker: The effects of mammalian posterior lobe hormones on the swelling of liver and kidney mitochondria in the rat and the dog. Biochim. biophys. Acta (Amst.) 74, 519–524 (1963a).

    Article  CAS  Google Scholar 

  • Greenbaum, A.L., and S.E. Dicker —: The swelling of mitochondria from the liver and kidney of a primitive rodent. Biochem. biophys. Res. Commun. 12, 402–404 (1963b).

    Article  CAS  PubMed  Google Scholar 

  • Griffith, L.D., R.E. Bulger, and B.F. Trump: The ultrastructure of the functioning kidney. Lab. Invest. 16, 220–246 (1967).

    CAS  PubMed  Google Scholar 

  • Guhl, U.: Die antidiuretische und pressorische Wirksamkeit von Arginin8-Vasopressin, Lysin8-Vasopressin und Phenylalanin2-Lysin8-Vasopressin beim Menschen. Schweiz, med. Wschr. 91, 798–805 (1961).

    CAS  Google Scholar 

  • Guinnebault, M.: Mise en Evidence du Role de l’Aldosterone dans le Mécanisme de Concentration de l’Urine. Rev. Franc. d’Etudes Cliniques et Biol. 7, 920–926 (1962).

    CAS  Google Scholar 

  • Gulyassy, P. F., and I. S. Edelman: Hydrogenion dependence of the antidiuretic action of vaso-pressin, oxytocin and deaminooxytocin. Biochim. biophys. Acta (Amst.) 102,185–197 (1965).

    Article  CAS  Google Scholar 

  • Guzek, J.W., and H. Lesnik: Antidiuretic activity of the hypothalamus, neurohypophysis and blood plasma in various states of water metabolism in the guinea pig. Bulletin de l’Académie Polonaise des Sciences 14, 723–726 (1966).

    CAS  PubMed  Google Scholar 

  • Ham, G. C.: Reproducible diuresis and chloruresis for bioassay of antidiuretic activity. Proc. Soc. exp. Biol. (N.Y.) 53, 210–213 (1943).

    CAS  Google Scholar 

  • —, and E.M. Landis: A comparison of pituitrin with antidiuretic substance found in human urine and placenta. J. clin. Invest. 21, 455–470 (1942).

    Article  CAS  PubMed  Google Scholar 

  • Hancox, N.M., and J. Komender: Quantitative and qualitative changes in the “dark” cells of the renal collecting tubules in rats deprived of water. Quart. J. exp. Physiol. 48, 346–354 (1963).

    CAS  PubMed  Google Scholar 

  • Handler, J.S., and J. Orloff: Activation of phosphorylase in toad bladder and mammalian kidney by antidiuretic hormone. Amer. J. Physiol. 205, 298–302 (1963).

    CAS  PubMed  Google Scholar 

  • Hanssen, O.E.: Early post mortem renal changes studied in mice with one kidney exteriorized. II. The functional and the early post mortem morphology of the kidney. Acta path, micro-biol. scand. 49, 297–320 (1960).

    Article  Google Scholar 

  • Hare, K., R.C. Hickey, and R.S. Hare: The renal excretion of an antidiuretic substance in the dog. Amer. J. Physiol. 134, 240–244 (1941).

    CAS  Google Scholar 

  • —, E.V. Melville, G.H. Chambers, and R.S. Hare: The assay of antidiuretic material in blood and urine. Endocrinology 36, 323–331 (1945).

    Article  CAS  Google Scholar 

  • Hare, R.S., K. Hare, and D.M. Philips: The renal excretion of chloride by the normal and by the diabetes insipidus dog. Amer. J. Physiol. 140, 334–348 (1944).

    Google Scholar 

  • Hays, R.M., and A. Leaf: The problem of clinical vasopressin resistance. In vitro studies. Ann. intern. Med. 54, 700–709 (1961).

    Article  CAS  Google Scholar 

  • Heidenreich, O., Y. Kook, V. Ling u. H. Menzel: Der Einfluß von Oxytocin auf die Nierendurchblutung und die Größe des Glomerulusfiltrats bei normalen und total hypophysecto-mierten Hunden. Arch. exp. Pathol. Pharmakol. 239, 328–335 (1960).

    CAS  Google Scholar 

  • Heintz, R., E. F. Drews, G. Drews u. H. Brass: Untersuchungen über den Gehalt des menschlichen Plasmas an antidiuretischem Hormon mit einer verbesserten Methode zum Hormonnachweis. Klin. Wschr. 42, 771–776 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Heller, H.: Antidiuretic substances. J. Pharm. Pharmacol. 3, 609–630 (1951).

    Article  CAS  PubMed  Google Scholar 

  • —: The active principles of the neurohypophysis. J. Pharm. Pharmacol. 7, 225–247 (1955).

    Article  CAS  PubMed  Google Scholar 

  • —: (Ed.): The Neurohypophysis. London: Butterworths 1957.

    Google Scholar 

  • —: Die Hypophysenhinterlappen-und Nebennierenrindenhormone während der ersten Lebenszeit im Zusammenhang mit der Regulation des Wasserhaushaltes. Mschr. Kinderheilk. 106, 81–87 (1958).

    CAS  PubMed  Google Scholar 

  • —, and K.E. Blackmore: The assay of small amounts of antidiuretic activity by intravenous injection into mice. J. Endocr. 8, 224–228 (1952).

    Article  CAS  PubMed  Google Scholar 

  • —, and R. P. Stephenson: Effect of posterior pituitary extract and its fractions on renal electrolyte excretion. Nature (Lond.) 165, 189 (1950).

    Article  CAS  Google Scholar 

  • Heller, J., and J. Stulc: Physiology of the antidiuretic hormone. I. A simple titration method. Physiol. bohemoslov. 8, 558–564 (1959).

    Google Scholar 

  • Hellman, E.S., D.P. Tschudy, and F.C. Bartter: Abnormal electrolyte and water metabolism in acute intermittent porphyria. The transient inappropriate secretion of antidiuretic hormone. Amer. J. Med. 32, 734–747 (1962).

    Article  CAS  PubMed  Google Scholar 

  • Herken, H.: Schlußwort zu der Veröffentlichung von E. Buchborn: Vasopressin und Ödementstehung. Dtsch. med. Wschr. 48, 2137 (1958).

    Article  Google Scholar 

  • Herms, W., and R.L. Malvin: Effect of metabolic inhibitors on urine osmolality and electrolyte excretion. Amer. J. Physiol. 204, 1065–1070 (1963).

    CAS  PubMed  Google Scholar 

  • Hickey, R.C., K. Hare, and R.S. Hare: Some cytological and hormonal changes in the posterior lobe of the rat’s pituitary after water deprivation and stalk section. Anat. Rec. 81, 319–322 (1941).

    Article  Google Scholar 

  • Hilger, H.H., J.D. Klümper u. K.J. Ullrich: Wasserrückresorption und Ionentransport durch die Sammelrohrzellen der Säugetierniere. Pflügers Arch. ges. Physiol. 267, 218–237 (1958).

    Article  CAS  Google Scholar 

  • Hilton, J.G., L.F. Sctan, C.D. Westermann, and O.R. Krueri: Direct stimulation of adrenocortical secretion by synthetic vasopressin in dogs. Proc. Soc. exp. Biol. (N.Y.) 100, 523–525 (1959).

    CAS  Google Scholar 

  • Hollander, W. Jr., T.F. Williams, C.C. Fordham, and L.G. Welt: III. A study of the quantitative relationship between antidiuretic hormone (vasopressin) and the renal tubular reabsorption of water. J. clin. Invest. 36, 1059–1071 (1957).

    Article  CAS  PubMed  Google Scholar 

  • Holmes, W.N., and B.M. Adams: Effects of adrenocortical and neurohypophysial hormones on the renal excretory pattern in the water loaded duck. Endocrinology 73, 5–10 (1963).

    Article  CAS  PubMed  Google Scholar 

  • Hope, D. B., V. V. S. Murti, and V. Dit Vigneatjd: A highly potent analogue of oxytocin, des-amino-oxytocin. J. biol. Chem. 237, 1563–1567 (1962).

    CAS  PubMed  Google Scholar 

  • Horster, F.A., G. Kuschinsky u. G. Peters: Die diuretische Wirkung von Oxytocin beim Hund. Arch. exp. Pathol. Pharmakol. 237, 241–246 (1959).

    CAS  Google Scholar 

  • Huguenin, R.L., E. Stürmer, R.A. Boissonnas, and B. Berde: Desamino-arginine-vaso-pressin. An analogue of arginine-vasopressin with high antidiuretic activity. Experientia (Basel) 21, 68 (1965).

    Article  CAS  Google Scholar 

  • Hunter, J., H. Kalant, and J.C. Ogilvie: A simple method for the assay of small amounts of antidiuretic hormone. Canad. J. Biochem. 37, 1215–1225 (1959).

    Article  CAS  PubMed  Google Scholar 

  • Jacobsen, A., A. Grieco, and S. J. Farber: Hexosamine analysis of renal papillae in diuretic and antidiuretic rats. Proc. Soc. exp. Biol. (N.Y.) 115, 1153–1156 (1964).

    Google Scholar 

  • Jacobson, H.N., and R.H. Kellogg: Isotonic NaCl diuresis in rats. Antidiuresis and chlor-uresis produced by posterior pituitary extracts. Amer. J. Physiol. 184, 376–389 (1956).

    CAS  PubMed  Google Scholar 

  • Jaenike, J. H.: The relative rates of urea and water permeation in the distal nephron of the intact kidney. J. clin. Invest. 43, 45–55 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Jaenike, J. R.: The influence of vasopressin on the permeability of the mammalian collecting duct to urea. J. clin. Invest. 40, 144–151 (1961).

    Article  CAS  PubMed  Google Scholar 

  • —: Acute effects of the administration of vasopressin during water diuresis in the dog. J. clin. Invest. 42, 161–170 (1963).

    Article  CAS  PubMed  Google Scholar 

  • —, and R. W. Berliner: A study of distal renal tubular functions by a modified stop flow technique. J. clin. Invest. 39, 481–490 (1960).

    Article  CAS  PubMed  Google Scholar 

  • —, and G. A. Bray: Effects of acute transitory urinary obstruction in the dog. Amer. J. Physiol. 199, 1219–1222 (1960).

    CAS  PubMed  Google Scholar 

  • —, and C. Waterhofse: The renal response to sustained administration of vasopressin and water in man. J. clin. Endocr. 21, 231–243 (1961).

    Article  CAS  PubMed  Google Scholar 

  • Jamison, R.L., C.M. Bennett, and R.W. Berliner: Counter current multiplication by the thin loops of Henle. Amer. J. Physiol. 212, 357–366 (1967).

    CAS  PubMed  Google Scholar 

  • Jeffers, W. A., M. A. Livezey, and J.H. Austin: A method for demonstrating an antidiuretic action of minute amounts of pitressin, statistical analysis of results. Proc. Soc. exp. Biol. (N.Y.) 50, 184–188 (1942).

    CAS  Google Scholar 

  • Jones, J. J., and J. Lee: The value of the pre-operated rat in the bioassay of vasopressin. J. Endocr. 33, 329–330 (1965).

    Article  CAS  PubMed  Google Scholar 

  • —: The value of rats with hereditary hypothalamic diabetes insipidus for the bioassay of vasopressin. J. Endocr. 37, 335–344 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Jones, N.F., M.A. Barraclough, and I.H. Mills: The mechanism of increased sodium excretion during water loading with 2.5% Dextrose and vasopressin. Clin. Sci. 25, 449–457(1963).

    CAS  PubMed  Google Scholar 

  • —, M. Mylle, and C.W. Gottschalk: Renal tubular microinjection studies in normal and potassium-depleted rats. Clin. Sci. 29, 261–275 (1965).

    CAS  PubMed  Google Scholar 

  • Jost, K., and J. Rudinger: Amino acids and peptides. Lxix. Synthesis of two biologically active analogues of deamino-oxytocin not containing a disulphide bond. Collection Czech. Chem. Commun. 32, 1229–1241 (1967).

    Article  CAS  Google Scholar 

  • Kasafirek, E., V. Rabek, J. Rudinger, and F. Sorm: Amino acids and peptides. Lxvi. Synthesis of ten extended-chain analogues of lysine-vasopressin. Collection Czech. Chem. Commun. 31, 4581–4591 (1966).

    Article  CAS  Google Scholar 

  • Kashiwagi, R.: Mechanism of the antidiuretic effect of vasopressin. Nature (Lond.) 184, 991 (1959).

    Article  CAS  Google Scholar 

  • Kaye, M.: An investigation into the cause of hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone. Amer. J. Med. 41, 910–926 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Kennedy, G.C.: The effect of adrenal steroids upon the secretion of hypotonie urine by the rat. J. Endocr. 20, 365–374 (1960).

    Article  CAS  PubMed  Google Scholar 

  • Kessler, E., R.L. Allen, Jr., D. Kirman, and H. Strauss: Effect of aldosterone and cortisol on sodium and water content of the rat kidney. Amer. J. Physiol. 207, 109–112 (1964).

    CAS  PubMed  Google Scholar 

  • Kestranek, W.H., H. Molitor u. E.P. Pick: Über die Wirkungsstärke von Hypophysen-extrakten, gemessen an ihren antidiuretischen Eigenschaften. Biochem. Z. 164, 34–43 (1925).

    CAS  Google Scholar 

  • Kiil, F., and K. Aukland: Renal tubular localization of water and sodium reabsorption in antidiuresis and water diuresis. Scand. J. clin. Lab. Invest. 12, 277–289 (1960)

    Article  CAS  PubMed  Google Scholar 

  • Kinne, R., W. V. Macfarlane, and O.E. Budtz-Olsen: Hormones and electrolytic excretion in sheep. Nature (Lond.) 192, 1084–1085 (1961).

    Article  CAS  Google Scholar 

  • Kleeman, C.R., M.H. Maxwell, and R. Rockney: Production of hypertonic urine in humans in the probable absence of antidiuretic hormone (ADH). Proc. Soc. exp. Biol. (N.Y.) 96, 189–191 (1957).

    CAS  Google Scholar 

  • Kleinman, L. I., E. P. Radford Jr., and G. Torelli: Urea and inulin clearances in undisturbed, unanesthetized rats. Amer. J. Physiol. 208, 578–584 (1965).

    CAS  PubMed  Google Scholar 

  • Kobinger, W.: Die Wirkung von Vasopressin auf die Konzentrationsgradienten von Natrium und Harnstoff im Nierengewebe bei verschiedenen Diuresezuständen. Naunyn-Schmiede-bergs Arch. exp. Path. Pharmak. 246, 538–551 (1964).

    CAS  Google Scholar 

  • Konzett, H.: Synthetische Analoge von Hypophysen-Hinterlappen-Hormonen. Arch. exp. Pathol. Pharmakol. 245, 153–166 (1963).

    CAS  Google Scholar 

  • Korr, J.H.: The osmotic function of the chicken kidney. J. cell. comp. Physiol. 13, 175–193 (1939).

    Article  CAS  Google Scholar 

  • Kramar, J., E.H. Grinell, and W.M. Duff: Studies on the renal activity of oxytocin. Amer. J. med. Sci. 252, 331–340 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Kupfer, S., and J.D. Kosovsky: The effects of intrarenal arterial injection of digitalis glyco-sides on urinary concentration. Fed. Proc. 21, 435–437 (1962).

    Google Scholar 

  • Kuriaki, K., et N. Baba: Effets de la vasopressine et de la serotonine sur l’anhydrase carbonique, la glutaminase-I, l’atpase et la phosphorylation oxydative dans le rein de rat. C.R. Soc. Biol. (Paris) 153, 1638–1640 (1959).

    CAS  Google Scholar 

  • Kühn, E.: Influence de l’antidiurese obtenu par infusion de l’arginine-vasopressine (AVP) de la lysine-vasopressine (LVP) et de l’ocytocine sur l’excretion du calcium chez la brebis. Arch. int. Pharmacodyn. 160, 480–484 (1966).

    PubMed  Google Scholar 

  • —, et G. Peeters: Influence de l’arginine-vasopressin sur l’excretion d’electrolytes chez le mouton. Arch. int. Pharmacodyn. 155, 455–458 (1965).

    PubMed  Google Scholar 

  • —: Influence de la secretion par voie reflexe des hormones post hypophysaires sur l’excre-tion du potassium chez la chevre. Arch. int. Pharmacodyn. 166, 214–215 (1967).

    PubMed  Google Scholar 

  • Lassiter, W.E., A. Prick, G. Rumrich, and K.J. Ullrich: Influence of ionic calcium on the water permeability of proximal and distal tubules in the rat kidney. Pflügers Arch. ges. Physiol. 285, 90–95 (1965).

    Article  CAS  Google Scholar 

  • —, M. Mylle, and C. W. Gottschalk: Micropuncture study of urea transport in rat renal medulla. Amer. J. Physiol. 210, 965–970 (1966).

    CAS  PubMed  Google Scholar 

  • Lauber, J.K.: A bio-assay and histochemical study of antidiuretic hormone in adrenalecto-mized rats. Amer. J. Physiol. 200, 898–900 (1961).

    CAS  PubMed  Google Scholar 

  • Lauson, H.D.: Antidiuretic hormone. Fed. Proc. 24, 731–736 (1965).

    CAS  PubMed  Google Scholar 

  • Lavietes, P.H., L.M. D’esopo, and H.E. Harrison: The water and base balance of the body. J. clin. Invest. 14, 251–265 (1935).

    Article  CAS  PubMed  Google Scholar 

  • Leaf, A.: Transepithelial transport and its hormonal control in toad bladder. Ergebn. Physiol. 56, 216–263 (1965).

    Article  CAS  PubMed  Google Scholar 

  • —, F.C. Bartter, R.F. Santos, and O. Wrong: Evidence in man that urinary electrolyte loss induced by pitressin is a function of water retention. J. clin. Invest. 32, 868–878 (1953).

    Article  CAS  PubMed  Google Scholar 

  • —, W.S. Kerr, O. Wrong, and J. Y. Chatillon: Effect of graded compression of the renal artery on water and solute excretion. Amer. J. Physiol. 179, 191–208 (1954).

    CAS  PubMed  Google Scholar 

  • —, and A. R. Mamby: The normal antidiuretic mechanism in man and dog, its regulation by extracellular fluid tonicity. J. clin. Invest. 31, 54–59 (1952).

    Article  CAS  PubMed  Google Scholar 

  • Lee, J.: Neurohypophysial hormones and fluid balance in hepatic cirrhosis. Thesis: London 1960.

    Google Scholar 

  • Lees, F., and M.F. Lockett: The influence of hypophysectomy and of adrenalectomy on the urinary changes induced by oxytocin in rats. J. Physiol. (Lond.) 17, 403–410 (1964).

    Google Scholar 

  • Leuschner, F.: Untersuchungen über die Wirkung des Vasopressins und analoger Polypeptide auf die Niere. Z. Vitamin-, Hormon-u. Fermentforsch. 11, 98–158 (1960).

    CAS  Google Scholar 

  • Lever, A.F.: The vasa recta and countercurrent multiplication. Acta med. scand. Suppl. 434, 33 pp. (1965).

    Google Scholar 

  • Levine, R., and J. A. Vogel: Cardiovascular and metabolic effects of cyclic adenosine 3′,5′-monophosphate in unanesthetized dogs. J. Pharmacol. exp. Ther. 151, 262–272 (1966).

    CAS  PubMed  Google Scholar 

  • Levine, R.A.: The antidiuretic action of adenosine 3′,5′-monophosphate (3′,5′-AMP) in man. J. clin. Invest. 45, 1039 (1966).

    Article  Google Scholar 

  • Levinsky, N.G., and R.W. Berliner: Changes in composition of the urine in ureter and bladder at low urine flows. Amer. J. Physiol. 196, 549–553 (1959).

    CAS  PubMed  Google Scholar 

  • —, D.G. Davidson, and R.W. Berliner: Changes in urine concentration during prolonged administration of vasopressin and water. Amer. J. Physiol. 196, 451–456 (1959).

    CAS  PubMed  Google Scholar 

  • Levitin, H., A. Goodman, G. Pigeon, and P.H. Epstein: Composition of renal medulla during water diuresis. J. clin. Invest. 41, 1145–1152 (1962).

    Article  CAS  PubMed  Google Scholar 

  • Levkoff, A.H., T.W. Demunbrun, and A.D. Keller: Disparity between fluid intake and renal concentrating capacity in dogs with diabetes insipidus. Amer. J. Physiol. 176, 25–32 (1954).

    CAS  PubMed  Google Scholar 

  • Lilien, O.M., and R. Spitzer: The countercurrent system and osmotic diuresis. J. Urol. (Baltimore) 92, 9–16 (1964).

    CAS  Google Scholar 

  • Lindemann, R.D., H.C. Von Buren, and L.G. Raisz: Effect of steroids on water diuresis and vasopressin sensitivity. J. clin. Invest. 40, 152–158 (1961).

    Article  Google Scholar 

  • Lindquist, K.M., and L.W. Rowe: The antidiuretic activity of the posterior pituitary and its quantitative evaluation. J. Amer, pharm. Ass. 38, 227–232 (1949).

    Article  CAS  Google Scholar 

  • Linkenbach, H.J., P. Eckert u. O.H. Gatter: Nachweis eines diuretischen Faktors im menschlichen Serum während der durch Expansion des intrathorakalen Blutvolumens ausgelösten Diurèse. Pflügers Arch. ges. Physiol. 293, 107–114 (1967).

    Article  CAS  Google Scholar 

  • Lipsett, M.B., I.L. Schwartz, and N.A. Thorn: Hormonal control of sodium, potassium, chloride and water metabolism. Mineral Metab. 1 B, 473–549. New York: Academic Press 1961.

    Google Scholar 

  • Little, J.B., and E.P. Radford: Bio-assay for antidiuretic activity in blood of undisturbed rats. J. appl. Physiol. 19, 179–186 (1964).

    CAS  PubMed  Google Scholar 

  • Little, J.M., S.L. Wallace, E.C. Whatley, and G. A. Anderson: Effect of pitressin on the urinary excretion of chloride and water in the human. Amer. J. Physiol. 151, 174–185 (1947).

    CAS  PubMed  Google Scholar 

  • Lockett, M.F., and T. Lima: The failure of neurohypophyseal hormones to prevent excessive loss of sodium from isolated cat kidneys perfused with blood drawn from headless donors. Arch. Int. Physiol. Biochim. 69, 327–328 (1961).

    Article  CAS  PubMed  Google Scholar 

  • —, and E.N. Roberts: Some actions of growth hormone on the perfused cat kidney. J. Physiol. (Lond.) 169, 879–888 (1963).

    CAS  Google Scholar 

  • Lundsgaard, E.: The effect of phloridzin on the isolated kidney and isolated liver. Scand. Arch. Physiol. 72, 265–270 (1935).

    Article  CAS  Google Scholar 

  • Macfarlane, W.V., R. Kinne, C.M. Wohnsley, B.D. Siebert, and D. Peter: Vasopressin and the increase of water and electrolyte excretion by sheep, cattle and camels. Nature (Lond.) 214, 979–981 (1967).

    Article  CAS  Google Scholar 

  • Malvin, R.L., and M.M. Fusco: Alteration in the countercurrent gradient by lesion in the median eminence. Nature (Lond.) 212, 1591–1592 (1966).

    Article  CAS  Google Scholar 

  • —: Renal function in unanesthetized normal and diabetes insipidus rats. J. appl. Physiol. 22, 380–382 (1967).

    CAS  PubMed  Google Scholar 

  • Manchester, R. C.: Influence of posterior pituitary extracts on mineral and water exchange in children. Proc. Soc. exp. Biol. (N.Y.) 29, 717–719 (1932).

    Google Scholar 

  • Marsh, D.J.: Hypo-osmotic reabsorption due to active salt transport in perfused collecting ducts of the rat renal medulla. Nature (Lond.) 210, 1179–1180 (1966).

    Article  CAS  Google Scholar 

  • Marshall, S., T.B. Miller, and A.E. Farah: Effect of renal papillectomy on ability of the hamster to concentrate urine. Amer. J. Physiol. 204, 363–368 (1963).

    Google Scholar 

  • Martin, G.J., J.N. Moss, and R.D. Smyth: Vasopressin potentiation and stimulation by bromelain. Arch. int. Pharmacodyn. 152, 445–449 (1964).

    CAS  PubMed  Google Scholar 

  • Marx, H.: Zur Theorie der Diurese. Klin. Wschr. 9, 2384 (1930).

    Article  CAS  Google Scholar 

  • Mathé, G., et J. Altmann: Contribution expérimentale a l’étude de l’inactivation hépatique de la pitressine. Presse méd. 62, 983–985 (1954).

    PubMed  Google Scholar 

  • McCann, S. M., J. Antunes-Rodrigues, R. Nallar, and H. Valtin: Pituitary-Adrenal function in the absence of vasopressin. Endocrinology 79, 1058–1064 (1966).

    Article  CAS  PubMed  Google Scholar 

  • McCreary, A.B., J.Q. Adams, and R.R. Overman: A bioassay technique for plasma antidiuretic activity. J. Lab. clin. Med. 49, 626–629 (1957).

    CAS  PubMed  Google Scholar 

  • McDonald, S.J., and H.E. De Wardener: Some observations on the production of a hypo-osmotic urine during the administration of 0.9% saline and vasopressin in the dog. Clin. Sci. 28, 445–459 (1965).

    CAS  PubMed  Google Scholar 

  • Mees, E. J.D.: Reversible water losing state, caused by incomplete ureteric obstruction. Acta med. scand. 168, 193–197 (1960).

    Article  Google Scholar 

  • Meroney, W.H., M.E. Rubini, and W.B. Blythe: The effect of antecedent diet on urine concentrating ability. Ann. intern. Med. 48, 562–573 (1958).

    Article  CAS  PubMed  Google Scholar 

  • Mertz, D. P.: Über die akute Wirkung von synthetischem Oxytocin auf die Nierenhämo-dynamik und renale Elektrolytausscheidung beim Menschen. Naunyn-Schmiedebergs Arch. exp. Path. Pharmak. 239, 410–424 (1960).

    CAS  Google Scholar 

  • —: Zur Frage einer Beteiligung von Nichtelektrolyten (Harnstoff, Kreatinin) am Vorgang der Harnkonzentrierung beim Menschen. Klin. Wschr. 43, 661–673 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Miller, L., L. Fisch, and C.R. Kleeman: Comparative potency of the antidiuretic hormones lysine8-and arginine8-vasopressin in humans. J. clin. Invest. 44, 1075–1076 (1965).

    Google Scholar 

  • C.R. Kleeman —: Relative potency of arginine8-vasopressin and lysine8-vasopressin in humans. J. Lab. clin. Med. 69, 270–291 (1967).

    CAS  PubMed  Google Scholar 

  • Moll, J., and D. De Wied: Observations on the hypothalamo-posthypophyseal system of the posterior lobectomized rat. Gen. comp. Endocr. 2, 215–228 (1962).

    Article  CAS  PubMed  Google Scholar 

  • Morel, F., M. Mylle, and C.W. Gottschalk: Tracer microinjection studies of effect of ADH on renal tubular diffusion of water. Amer. J. Physiol. 209, 179–187 (1965).

    CAS  PubMed  Google Scholar 

  • Morrison, S.D., C. Mackay, E. Hurlbrink, J.K. Wier, M.S. Nick, and F.K. Miller: The water exchange and polyuria of rats deprived of food. Quart. J. exp. Physiol. 52, 51–67 (1967).

    CAS  Google Scholar 

  • Motzfeldt, K.: Experimental studies on the relation of the pituitary body to renal function. J. exp. Med. 25, 153–188 (1917).

    Article  CAS  PubMed  Google Scholar 

  • Munsick, R.A.: Neurohypophysial hormones of chickens and turkeys. Endocrinology 75, 104–112 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —, W.H. Sawyer, and H.B. Van Dyke: The antidiuretic potency of arginine-and lysine-vasopressin in the pig with observations on porcine renal function. Endocrinology 63, 688–693 (1958).

    Article  CAS  PubMed  Google Scholar 

  • Murphy, R. J.F.: Studies on the mechanisms of saline diuresis. J. clin. Invest. 29, 836 (1950).

    Article  CAS  PubMed  Google Scholar 

  • Nelson, E.E., and G.G. Woods: The diuretic-antidiuretic activity of posterior pituitary extracts. J. Pharmacol, exp. Ther. 50, 241–253 (1934).

    CAS  Google Scholar 

  • Nielsen, AA, Th.: A note on the relative antidiuretic potency of beef and hog vasopressin. Acta endocr. (Kbh.) 29, 561–564 (1958).

    CAS  Google Scholar 

  • —: Dissimilarity between arginine and lysine vasopressin in rat pressor assays. Acta endocr. (Kbh.) 35, 299–311 (1960).

    CAS  Google Scholar 

  • —: Hypofysebaglapshormoner. København: Kandrup & Wunsch Bogtrykkeri 1964 [Thesis in Danish, with summary in English].

    Google Scholar 

  • —: On the antidiuretic activity of Phe2-Lys8-vasopressin in the rat. Acta endocr. (Kbh.) 49, 312–319 (1965).

    CAS  Google Scholar 

  • Nielsen, B.: Correlation between antidiuretic hormone effect and the renal excretion of magnesium and calcium in man. Acta endocr. (Kbh.) 45, 151–160 (1964).

    CAS  Google Scholar 

  • —, and N. A. Thorn: Transient excess urinary excretion of antidiuretic material in acute intermittent porphyria with hyponatremia and hypomagnesiemia. Amer. J. Med. 38, 345–358 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Niesel, W., u. H. Röskenbleck: Konzentrierung von Lösungen unterschiedlicher Zusammensetzung durch alleinige Gegenstromdiffusion und Gegenstromosmose als möglicher Mechanismus der Harnkonzentrierung. Pflügers Arch. ges. Physiol. 283, 230–241 (1965).

    Article  CAS  Google Scholar 

  • Nissen, O.I.: The filtration fractions of plasma supplying the superficial and deep venous drainage area of the cat kidney. Acta physiol. scand. 68, 275–285 (1966).

    Article  Google Scholar 

  • Nusynowitz, M.L., L.G. Wegienka, B.F. Bower, and P.H. Forsham: Effect on vasopressin action of analgesic drugs in vitro Amer. J. Med. Sci 252, 424–428 (1966).

    Article  CAS  Google Scholar 

  • O’connor, W. J.: The role of the neurohypophysis of the dog in determining urinary changes and the antidiuretic activity of the urine following the administration of sodium chloride or urea. Quart. J. exp. Physiol. 36, 21–48 (1950).

    CAS  Google Scholar 

  • Orloff, J., and J.S. Handler: The cellular mode of action of antidiuretic hormone. Amer. J. Med. 36, 686–697 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —: The role of adenosine 3′. 5′-phosphate in the action of antidiuretic hormone. Amer. J. Med. 42, 757–768 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Osvaldo, L., and H. Latta: The thin limbs of the loop of Henle. J. Ultrastruct. Res. 15, 144–168 (1966a).

    Article  CAS  PubMed  Google Scholar 

  • —: Interstitial cells of the renal medulla. J. Ultrastruct. Res. 15, 589–613 (1966b).

    Article  CAS  PubMed  Google Scholar 

  • Ottoson, D., F. Sjostrand, S. Stenström, and G. Svaeticehin: Microelectrode studies on the E.M.F. of the frog skin related to electron microscopy of the dermo-epidermal junction. Acta physiol. scand. 29 suppl. 106, 611–624 (1953).

    Google Scholar 

  • Papper, S., L. Saxon, M.B. Burg, H.W. Seifer, and J.D. Rosenbaum: The effect of morphine sulfate upon the renal excretion of water and solute in man. J. Lab. clin. Med. 50, 692–704 (1957).

    CAS  PubMed  Google Scholar 

  • Peachey, L., and H. Rasmussen: Structure of the toad urinary bladder as related to its physiology. J. biophys. biochem. Cytol. 10, 529–553 (1961).

    Article  CAS  PubMed  Google Scholar 

  • Pena, J.C., and R.L. Malvin: Transcellular diffusion of non-electrolytes across the renal tubular epithelium. J. gen. Physiol. 45, 643–649 (1962).

    Article  CAS  PubMed  Google Scholar 

  • Perlmutt, J. H.: Renal activity of vasopressin in anesthetized dogs. Amer. J. Physiol. 200, 400–404 (1961).

    CAS  PubMed  Google Scholar 

  • —: Influence of hydration on renal function and medullary sodium during vasopressin infusion. Amer. J. Physiol. 202, 1098–1104 (1962).

    CAS  PubMed  Google Scholar 

  • Petersen, M. J., and I. S. Edelmann: Calcium inhibition of the action of vasopressin on the urinary bladder of the toad. J. clin. Invest. 43, 583–594 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Philippson, CHR.: Der Gehalt an Glycerylphosphorylcholin und Glycerylphosphoryläthanol-amin von Nierenmark und Nierenrinde hochreiner Wistarratten während forcierter Wasser-diurese und extrem langer Durst-Antidiurese. Pflügers Arch. ges. Physiol. 280, 30–37 (1964).

    Article  CAS  Google Scholar 

  • Pickford, M.: Neurohypophysis and kidney function. In: The pituitary gland, Vol. 3. Ed. by G.W. Harris and B.T. Donovan. London: Butterworths 1966.

    Google Scholar 

  • Pigeon, G., and H. Epstein: Water uptake in the intact frog. Amer. J. Physiol. 204, 217–221 (1963).

    CAS  PubMed  Google Scholar 

  • Pliska, V., and I. Krejči: The dose-response relation of the antidiuretic and vasopressor activities of 4-asparagine8lysine-vasopressin. Arch. int. Pharmacodyn. 161, 289–297 (1966).

    CAS  PubMed  Google Scholar 

  • —, and I. Rychlik: Determination of antidiuretic activity in the rat for structural analogues of the neurohypophysial hormones. Acta endocr. (Kbh.) 54, 129–140 (1967).

    CAS  Google Scholar 

  • Poisner, A. M.: Interaction of oxytocin and vasopressin with ß-adrenergic receptors in the kidney. Nature (Lond.) 201, 199–200 (1964).

    Article  CAS  Google Scholar 

  • Poulson, T.L.: Countercurrent multipliers in avian kidneys. Science 148, 389–391 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Poy, R.F.K.P., and P.J. Bentley: Fine structure of the epithelial cells of the toad urinary bladder. Exp. Cell. Res. 20, 235–237 (1960).

    Article  Google Scholar 

  • Rabasa, S.L., and F. Bergman: A method to measure the renal sensitivity to ADH in the rat. Acta physiol. lat.-amer. 14, 89–93 (1964).

    CAS  PubMed  Google Scholar 

  • Radford, E. P.: Factors modifying water metabolism in rats fed dry diets. Amer. J. Physiol. 196, 1098–1108 (1959).

    CAS  PubMed  Google Scholar 

  • Raisz, L.G., W.F. McNeely, L. Saxon: Studies on the renal concentrating mechanism. J. Lab. clin. Med. 52, 437–445 (1958).

    CAS  PubMed  Google Scholar 

  • L. Saxon —, and J.D. Rosenbaum: The effects of cortisone and hydrocortisone on water diuresis and renal function in man. J. clin. Invest. 36, 767–779 (1957).

    Article  CAS  PubMed  Google Scholar 

  • Ralli, E.P., L.G. Raisz, S.H. Leslie, M.E. Dumm, and B. Laken: Evidence for more than one antidiuretic substance in pitressin. Amer. J. Physiol. 163, 141–147 (1950).

    CAS  PubMed  Google Scholar 

  • Rallison, M.L., and F.H. Tyler: Treatment of diabetes insipidus in children with lysine8-vasopressin. J. Pediat. 70, 122–125 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Robert, F.: Über die Einwirkung von Hypophysin und seine Fraktionen auf den Wassersalzstoffwechsel. Arch. exp. Pathol. Pharmakol. 164, 367–371 (1932).

    Article  CAS  Google Scholar 

  • Robinson, J.D.: Interaction between protein sulphydryl groups and lipid double bonds in biological membranes. Nature (Lond.) 212, 199–200 (1966).

    Article  CAS  Google Scholar 

  • Robinson, J.H., Jr., and L.E. Farr: Relation between clinical oedema and excretion of antidiuretic substance in the urine. Ann. intern. Med. 14, 42–54 (1940).

    Article  CAS  Google Scholar 

  • Robinson, K.W., and W.V. Macfarlane: Plasma antidiuretic activity of marsupials during exposure to heat. Endocrinology 60, 679–680 (1957).

    Article  CAS  PubMed  Google Scholar 

  • Robinson, R.R., and E.E. Owen: Intrarenal distribution of ammonia during diuresis and antidiuresis. Amer. J. Physiol. 208, 1129–1134 (1965).

    CAS  PubMed  Google Scholar 

  • —, and B. Schmidt-Nielsen: Intra-renal distribution of free amino acids in antidiuretic ruminants. Comp. Biochem. Physiol. 19, 187–195 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Robson, J. S.: Factors affecting renal concentrating ability. Electron-microscopic study of the kidney during antidiuresis, diuresis and potassium depletion. In: Hormones and the Kidney. Ed. by P.C. Williams. Mem. Soc. Endocr. No. 13, p. 105–119. New York: Academic Press 1963.

    Google Scholar 

  • Roemmelt, J.C., O.W. Sartorius, and R.F. Pitts: Excretion and reabsorption of sodium and water in the adrenalectomized dog. Amer. J. Physiol. 159, 124–136 (1949).

    CAS  PubMed  Google Scholar 

  • Rosas, R., L. Barnafi, T. Pereda, and H. Croxatto: Effect of oxytocin structural changes on rat renal excretion of Na, K and water. Amer. J. Physiol. 202, 901–904 (1962).

    CAS  PubMed  Google Scholar 

  • Rosenbaum, J.D., R.K. Davis, and B.C. Ferguson: The influence of cortisone on water diuresis in man. J. clin. Invest. 30, 668 (1951).

    Google Scholar 

  • Rosenfeld, J.B., K. Hirata, A.N. Brest, and J. H. Moyer: Effect of large doses of hyaluronidase upon urine concentration in dogs. Israel. J. Med. Sci. 3, 119–130 (1967).

    CAS  PubMed  Google Scholar 

  • Rosenfeld, S., A.L. Sellers, and J. Katz: Development of an isolated perfused mammalian kidney. Amer. J. Physiol. 196, 1155–1159 (1959).

    CAS  PubMed  Google Scholar 

  • Ruch, W.: Estimation of antidiuretic hormone in the urine of healthy subjects and patients with inappropriate secretion of vasopressin (Schwartz-Bartter syndrome). Acta endocr. (Kbh.) 54, 113–121 (1967).

    CAS  Google Scholar 

  • Rudinger, J.: Synthetic analogues of oxytocin with inhibitor activity or protracted action. Excerpta Med. Int. Congr. Ser. No. 83, p. 1202–1206. London 1964.

    Google Scholar 

  • —: (Ed.) Oxytocin, vasopressin and their structural analogues. Proc. 2nd Int. Pharmacol. Meeting, Praha, Aug. 1963. Oxford: Pergamon Press; Praha: Czech. Med. Press 1964a.

    Google Scholar 

  • Rudinger, J., and K. Jost: A biologically active analogue of oxytocin not containing a disulfide group. Experientia (Basel) 20, 570 (1964).

    Article  CAS  Google Scholar 

  • Ruiz-Guinazu, A., E.E. Arrizurieta, and L. Yelinek: Electrolyte, water and urea concent in dog kidneys in different states of diuresis. Amer. J. Physiol. 206, 725–730 (1964).

    CAS  PubMed  Google Scholar 

  • Sabour, M.S., M.K. MacDonald, A.T. Lambie, and J.S. Robson: The electron microscopic appearance of the kidney in hydrated and dehydrated rats. Quart. J. exp. Physiol. 49, 162–170 (1964).

    CAS  PubMed  Google Scholar 

  • Saikia, T. C. Composition of the renal cortex and medulla of rats during water diuresis and antidiuresis. Quart. J. exp. Physiol. 50, 146–157 (1965a).

    CAS  PubMed  Google Scholar 

  • —: The acute effect of vasopressin upon the composition of the rat renal cortex and medulla. Quart. J. exp. Physiol. 50, 158–168 (1965b).

    CAS  PubMed  Google Scholar 

  • Sakai, F., M. Tadokoro, and J. Yamaguchi: Osmolality of loop of Henle fluid in golden hamster. Jap. J. Pharmacol. 16, 492 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Samaan, A.: The effect of pituitary (posterior lobe) extract upon the urinary flow in non-anaesthetized dogs. J. Physiol. (Lond.) 85, 37–46 (1935).

    CAS  Google Scholar 

  • Sanyal, N.N., and R.S. Snart: Absorption of octapeptide hormones on to lipid monolayers. Nature (Lond.) 1, 798–799 (1967).

    Article  Google Scholar 

  • Sartorius, O.W., and K. Roberts: The effects of pitressin and desoxycorticosterone in low dosage on the excretion of sodium, potassium and water by the normal dog. Endocrinology 45, 273–283 (1949).

    Article  CAS  PubMed  Google Scholar 

  • Saunders, W. G., and R. A. Munsick: Antidiuretic potency of oxytocin in women post partum. Amer. J. Obstet. Gynec. 95, 5–11 (1966).

    CAS  PubMed  Google Scholar 

  • Sawyer, W. H.: Posterior pituitary extracts and excretion of electrolytes by the rat. Amer. J. Physiol. 169, 583–587 (1952).

    CAS  PubMed  Google Scholar 

  • —: Differences in the antidiuretic response of rats to the intravenous administration of lysine and arginine vasopressin. Endocrinology 63, 694–698 (1958).

    Article  CAS  PubMed  Google Scholar 

  • —: Comparative physiology and pharmacology of the neurohypophysis. Rec. Progr. Horm. Res. 17, 437–465 (1961a).

    CAS  PubMed  Google Scholar 

  • —: Neurohypophysial hormones. Pharmacol. Rev. 13, 225–277 (1961b).

    CAS  PubMed  Google Scholar 

  • —: Biological assays for oxytocin and vasopressin. Meth. med. Res. 9, 210–219 (1961c).

    CAS  PubMed  Google Scholar 

  • —: Neurohypophyseal peptides and water excretion in the vertebrates. In: Hormones and the kidney. Ed. by P.C. Williams. Mem. Soc. Endocr. No. 13. London: Academic Press 1963.

    Google Scholar 

  • —: Biological assays for neurohypophysial principles in tissues and blood. In: The pituitary gland. Ed. by G.W. Harris and B.T. Donovan. London: Butterworths 1966.

    Google Scholar 

  • —, W.Y. Chan, and H.B. Van Dyke: Antidiuretic responses to neurohypophysial hormones and some of their synthetic analogues in dogs and rats. Endocrinology 71, 536–540 (1962).

    Article  CAS  PubMed  Google Scholar 

  • —, and H. Valtin: Inhibition of vasopressin antidiuresis by extracts of pituitaries from rats with hereditary hypothalamic diabetes insipidus and by oxytocin. Endocrinology 76, 999–1001 (1965).

    Article  CAS  PubMed  Google Scholar 

  • —: Antidiuretic responses of rats with hereditary hypothalamic diabetes insipidus to vasopressin, oxytocin and nicotine. Endocrinology 80, 207–210 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Scheer, R.L., L.G. Raiszand, and C.W. Lloyd: Changes in diabetes insipidus during pregnancy and lactation. J. clin. Endocr. 19, 805–811 (1959).

    Article  CAS  PubMed  Google Scholar 

  • Schmidt-Nielsen, B.: Urea excretion in mammals. Physiol. Rev. 38, 139–168 (1958).

    CAS  PubMed  Google Scholar 

  • Schoen, E.J.: Renal diabetes insipidus. Pediatrics 26, 808–816 (1960).

    CAS  PubMed  Google Scholar 

  • Schröder, R.: Herstellung und Funktion eines isolierten Nierenpräparates vom Hund. Pflügers Arch. ges. Physiol. 286, 189–198 (1965).

    Article  Google Scholar 

  • —: Die Wirkung einer Angiotensininfusion auf die Harnkonzentration des Menschen unter maximaler ADH-Wirkung. Pflügers Arch. ges. Physiol. 290, 193–201 (1966).

    Article  Google Scholar 

  • —, H.J. Buschmann u. K. Ehrentahl: Die Wirkung von Tonephin auf die rénale Elektrolyt-und Harnstoffausscheidung bei Infusion von Glucose und Sterofundin. Klin. Wschr. 44, 943–951 (1966).

    Article  PubMed  Google Scholar 

  • —, G. Meyer-Burgdorff, D. Rott u. O. Brahms: Vergleichende Untersuchungen über die Wirkung von ADH, Hypertensin und Renin auf renale Wasser-und Elektrolytausscheidung der Ratte. Arch. exp. Pathol. Pharmakol. 240, 285–312 (1961).

    Google Scholar 

  • Schwartz, I.L., and L.M. Livingston: Cellular and molecular aspects of the antidiuretic action of vasopressin and related peptides. Vitamins and Hormones 22, 261–358 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —, H. Rasmussen, and J. Rudinger: Activity of neurohypophysial hormone analogues lacking a disulfide bridge. Proc. nat. Acad. Sci. (Wash.) 52, 1044–1045 (1964).

    Article  CAS  Google Scholar 

  • Schwartz, W.B., and A.S. Relman: Effects of electrolyte disorders on renal structure and function. New Engl. J. Med. 276, 383–389 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Schwarz, W., u. J. Wolff: Veränderungen am Hauptstück und peritubulären Kapillaren der Rattenniere nach Hypophysectomie. Z. Zellforsch. 71, 441–454 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Self, J.: Water intoxication induced by oxytocin administration. Amer. J. med. Sci. 252, 573–574 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Selkurt, E.E.: Effect of ureteral blockade on renal blood flow and urinary concentrating ability. Amer. J. Physiol. 205, 286–292 (1963).

    CAS  PubMed  Google Scholar 

  • —, M. J. Elpers, and J. Womack: Effects of renal venous occlusion on renal haemodynamies and concentrating ability. Amer. J. Physiol. 207, 989–997 (1964).

    CAS  PubMed  Google Scholar 

  • Sellwood, R.V., and E.B. Verney: The effect of water and of isotonic saline administration on the renal plasma and glomerular filtrate flows in the dog with incidental observations on these flows of compression of the carotid arteries. Phil. Trans. B. 238, 361–396 (1955).

    Article  Google Scholar 

  • Shannon, J. A.: The control of the renal excretion of water. J. exp. Med. 76, 387–399 (1942).

    Article  CAS  PubMed  Google Scholar 

  • Share, L.: Acute reduction in extracellular fluid volume and the concentration of antidiuretic hormone in blood. Endocrinology 69, 925–933 (1961).

    Article  CAS  PubMed  Google Scholar 

  • Shuster, A., E. A. Alexander, R.C. Lalone, and N.G. Levinsky: Renal blood flow, sodium excretion and concentrating ability during saline infusion. Amer. J. Physiol. 211, 1181–1186 (1966).

    CAS  PubMed  Google Scholar 

  • Sigler, M.H., J.N. Forrest, and J.R. Elkington: Renal concentrating ability in the adre-nalectomized rat. Clin. Sci. 28, 29–37 (1965).

    CAS  PubMed  Google Scholar 

  • Silva, P., and M.S. Allan: Water intoxication due to high doses of synthetic oxytocin. Obstet, and Gynec. 27, 517–520 (1966).

    Article  CAS  Google Scholar 

  • Sinclair-Smith, B.C., J. Sisson, A.A. Kattus, A. Genecin, C. Monge, W. McKeever, and E.V. Newman: The effects of posterior pituitary extract and smoking on water, sodium and chloride excretion in normal subjects and in patients with congestive cardiac failures. Bull. Johns Hopk. Hosp. 87, 221–234 (1950).

    CAS  Google Scholar 

  • Skadhauge, E.: Effects of retrograde injections of vasopressin into the upper urinary tract of hydrated rats. Proc. Soc. exp. Biol. (N.Y.) 117, 807–810 (1964a).

    CAS  Google Scholar 

  • —: Effects of unilateral infusion of arginine-vasopressin into the portal circulation of the avian kidney. Acta endocr. (Kbh.) 47, 321–330 (1964b).

    CAS  Google Scholar 

  • —, and B. Schmidt-Nielsen: Renal function in domestic fowl. Amer. J. Physiol. 212, 793–798 (1967a).

    CAS  PubMed  Google Scholar 

  • —: The renal medullary electrolyte and urea gradient in chickens and turkeys. Amer. J. Physiol. 212, 1313–1318 (1967b).

    CAS  PubMed  Google Scholar 

  • Sloper, J. C.: The presence of a posterior pituitary-like structure in the hypothalamus after hypophysectomy. Acta endocr. suppl. 51, 101 (1960).

    Google Scholar 

  • Smith, F.M., and E.M. Mackay: Influence of posterior pituitary extracts on sodium balance in normal subjects and patients with diabetes insipidus. Proc. Soc. exp. Biol. (N.Y.) 34, 116–119 (1936).

    Google Scholar 

  • Smith, H.W. Principles of renal physiology. New York: Oxford University Press 1962.

    Google Scholar 

  • Smith, M. W.: The effect of hyaluronidase and cortisol on the inactivation of vasopressin by rat kidney slices. J. Endocrin. 24, 415–425 (1962).

    Article  CAS  Google Scholar 

  • Stein, M., R. Jinks, and I.A. Mirsky: The bioassay of pitressin and antidiuretic substances in blood and urine. Endocrinology 51, 492–501 (1952).

    Article  CAS  PubMed  Google Scholar 

  • Steiness, I., and M. Lunding: Pronounced polyuria and natriuresis following surgical relief of urinary tract obstruction. Acta med. scand. 180, 159–166 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Sternberg, W.H., E. Färber, and C.E. Dunlap: Histochemical localization of specific oxi-dative enzymes. J. Histochem. Cytochem. 4, 266–283 (1956).

    Article  CAS  PubMed  Google Scholar 

  • Stewart, J., and S.G. Spickett: Genetic variation in diuretic responses to water loads: Definition of some parameters of diuretic response and initial results of selection for these parameters. J. Endocr. 33, 417–428 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Studer, R.O., and W.D. Cash: Synthesis of 1acetyl8-arginine-vasopressin and a study of its effects in the rat pressor assay. J. biol. Chem. 238, 657–659 (1963).

    CAS  PubMed  Google Scholar 

  • Stürmer, E., R.L. Hugtjenin, R.A. Boissonnas, and B. Berde: Deamino1-phenylalanine2-arginine8-vasopressin: A peptide with highly selective antidiuretic activity. Experientia (Basel) 21, 583 (1965).

    Article  Google Scholar 

  • Swingle, W. W., L. J. Brannick, S. J. Le Brie, and A.F. Parlow: A histaminelike component of commercial pitressin. Proc. Soc. exp. Biol. (N.Y.) 91, 223–226 (1956).

    CAS  Google Scholar 

  • Tata, P.S., and O.H. Gatter: Vasopressin studies in the rat. I. A sensitive bioassay for exogenous vasopressin. Pflügers Arch. ges. Physiol. 290, 279–285 (1966).

    Article  CAS  Google Scholar 

  • Theobald, G. W.: The allerged relation of hyperfunction of the posterior lobe of the hypophysis to eclampsia and the nephropathy of pregnancy. Clin. Sci. 1, 225–239 (1934).

    CAS  Google Scholar 

  • Thoenes, W.: Die Mikromorphologie des Nephron in ihrer Beziehung zur Funktion II. Klin. Wschr. 39, 827–839 (1961).

    Article  CAS  PubMed  Google Scholar 

  • Thomas, S.: Washout and re-accumulation of urea during diuresis and antidiuresis. In: Hormones and the kidney. Ed. by P.C. Williams. Mem. Soc. Endocr. No. 13. New York: Academic Press 1963.

    Google Scholar 

  • —: Solute excretion in man during changing urine flow occurring spontaneously and induced by vasopressin injection. J. clin. Invest. 43, 1–10 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Thomson, W. B.: The effect of oxytocin and vasopressin and of phenylalanin3-oxytocin on the urinary excretion of water and electrolytes in man. J. Physiol. (Lond.) 150, 284–294 (1960).

    CAS  Google Scholar 

  • Thorn, N. A.: A densimetric method for assay of small amounts of antidiuretic hormone. J. exp. Med. 105, 585–590 (1957a).

    Article  CAS  PubMed  Google Scholar 

  • —: Mammalian antidiuretic hormone. Physiol. Rev. 38, 169–191 (1958).

    CAS  PubMed  Google Scholar 

  • —: Binding in vitro of highly-purified arginine-vasopressin and synthetic oxytocin to rat serum globulin. Acta endocr. (Kbh.) 30, 472–476 (1959a).

    CAS  Google Scholar 

  • —: Some chemical properties of antidiuretic material in the urine of rats. Acta endocr. (Kbh.) 32, 128–133 (1959b).

    CAS  Google Scholar 

  • —: Effect of highly purified arginine-and lysine-vasopressin on urinary excretion of sodium and potassium in hydrated rats. Acta endocr. (Kbh.) 32, 123–128 (1959c).

    CAS  Google Scholar 

  • —: Effects of arginine-, lysine-, and leucine-vasopressin on urinary osmolality and rate of urine flow in hydrated rats and dogs. Acta endocr. (Kbh.) 32, 134–141 (1959e).

    CAS  Google Scholar 

  • —: Antidiuretiske hormoner og deres Analoge. Thesis. København: Danish Science Press 1960a.

    Google Scholar 

  • —: An effect of antidiuretic hormone on renal excretion of calcium in dogs. Dan. med. Bull. 7, 109–112 (1960b).

    Google Scholar 

  • —: Effect of valyl3-oxytocin on renal excretion of sodium and potassium in hydrated rats and dogs. Dan. med. Bull. 7, 113–115 (1960c).

    CAS  PubMed  Google Scholar 

  • —: Correlation between antidiuretic hormone effect and changes in renal excretion of calcium in rats and dogs. Acta endocr. (Kbh.) 38, 563–570 (1961).

    CAS  Google Scholar 

  • —, and B. Milewski: Effect of leucine-vasopressin (phenyl-alanine-oxytocin) on renal excretion of sodium and potassium in hydrated rats and dogs. Proc. Soc. exp. Biol. (N.Y.) 100, 267–269 (1959d).

    CAS  Google Scholar 

  • —, and I.L. Schwartz: Effect of antidiuretic hormone on washout curves of radioactive calcium from isolated toad bladder tissue. Gen. comp. Endocr. 5, 710 (1965).

    Google Scholar 

  • — — Renal excretion of natural lysine-vasopressin injected into rats (unpublished).

    Google Scholar 

  • —, and L. Silver: Chemical form of circulating antidiuretic hormone in rats. J. exp. Med. 105, 575–583 (1957b).

    Article  CAS  PubMed  Google Scholar 

  • —, and I. Transbøl: Hyponatremia and bronchogenic carcinoma associated with renal excretion of large amounts of antidiuretic material. Amer. J. Med. 35, 257–268 (1963).

    Article  CAS  PubMed  Google Scholar 

  • —, and N.B.S. Willumsen: Inactivation of arginine-and lysine-vasopressin by slices from different zones of the rat kidney and by rat liver slices. Acta endocr. (Kbh.) 44, 545–562 (1963).

    CAS  Google Scholar 

  • Thorp, R.H.: Posterior pituitary hormones. In: Methods in hormone research. Vol. 2, Bio-assay, pp. 495–516. Ed. by R. J. Dorfman. New York: Academic Press 1962.

    Google Scholar 

  • Thurau, K.: Renal hemodynamics. Amer. J. Med. 36, 698–719 (1964).

    Article  CAS  PubMed  Google Scholar 

  • —, u. P. Deetjen: Bedeutung der Hämodynamik des Nierenmarkes für die Harnkonzentrierung. Pflügers Arch. ges. Physiol. 274, 567–580 (1962).

    Article  CAS  Google Scholar 

  • — u. P. Kramer: Hämodynamik des Nierenmarks. II. Wechselbeziehung zwischen vas-culärem Gegenstromsystem bei arteriellen Drucksteigerungen. Wasserdiurese und osmoti-scher Diurese. Pflügers Arch. ges. Physiol. 270, 270–285 (1960).

    Article  CAS  Google Scholar 

  • —, u. E. Wober: Zur Lokalisation der autoregulativen Widerstandsänderungen in der Niere. Pflügers Arch. ges. Physiol. 274, 553–566 (1962).

    Article  CAS  Google Scholar 

  • Torres, C., L. Schewitz, and V.E. Pollach: The effect of small amount of antidiuretic hormone on sodium and urate excretion in pregnancy. Amer. J. Obstet. Gynec. 94, 546–558 (1966).

    CAS  PubMed  Google Scholar 

  • Trueta, J., A.E. Barclay, P.M. Daniel, K.J. Franklin, and M.M.L. Pritchard: Studies of the renal circulation. Oxford: Blackwell 1947.

    Google Scholar 

  • Ullmann, T.D., W. J. Czackes, and J. Menczel: Modification of the antidiuretic effect of vasopressin by acid and alkaline loads. J. clin. Invest. 44, 754–764 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Ullrich, K.J.: Das Nierenmark, Struktur, Stoffwechsel und Funktion. Ergebn. Physiol. 50, 433–489 (1959).

    Article  CAS  PubMed  Google Scholar 

  • —, u. K.H. Jarausch: Untersuchungen zum Problem der Harnkonzentrierung und Verdünnung. Über die Verteilung der Elektrolyte (Na, K, Ca, Mg, Cl, anorg. Phosphat), Harnstoff, Aminosäuren und exogenem Kreatinin im Rinde und Mark der Hundeniere bei verschiedenen Diuresezuständen. Pflügers Arch. ges. Physiol. 262, 537–550 (1956).

    Article  CAS  Google Scholar 

  • —, and J. Marsh: Kidney, water and electrolyte metabolism. Ann. Rev. Physiol. 25, 91–142 (1963).

    Article  CAS  Google Scholar 

  • —, G. Pehling, A. Runz-Guinazu u. Espinar-Lafuente: Veränderung des Blutes bei der Passage durch das vasculäre Gegenstromsystem im Nierenmark. Pflügers Arch. ges. Physiol. 274, 64–65 (1961).

    Google Scholar 

  • Ullrich, K. J., G. Rumrich u. G. Fuchs: Wasserpenneabilität und transtubulärer Wasserfluß corticaler Nephronabschnitte bei verschiedenen Diuresezuständen. Pflügers Arch. ges. Physiol. 280, 99–119 (1964).

    Article  CAS  Google Scholar 

  • —, and B. Schmidt-Nielsen: Urea transport in the collecting duct of rats on normal and low protein diet. Pflügers Arch. ges. Physiol. 295, 147–156 (1967).

    Article  CAS  Google Scholar 

  • Ussing, H.H., P. Kruhøffer, J. Hess Thaysen, and N.A. Thorn: The alkali metal ions in biology. Handbuch d. exper. Pharmacol., Ergänzungswerk Bd. 13. Berlin-Göttingen-Heidelberg: Springer 1960.

    Google Scholar 

  • Valtin, H.: Sequestration of urea and nonurea solutes in renal tissues of rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin and dehydration on the counter-current mechanism. J. clin. Invest. 45, 337–345 (1966a).

    Article  CAS  PubMed  Google Scholar 

  • —: Effect of dehydration on urinary concentration in the absence of vasopressin. J. clin. Invest. 45, 1082 (1966b).

    Article  Google Scholar 

  • —: Hereditary hypothalamic diabetes insipidus in rats (a useful experimental model). Amer. J. Med. 42, 814–827 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Van Dyke, H.B., S.L. Engel, and K. Adamson, Jr.: Comparison of pharmacological effect of lysine and arginine vasopressin. Proc. Soc. exp. Biol. (N.Y.) 91, 484–486 (1956).

    Google Scholar 

  • —, W.H. Sawyer, and N.I. A. Overweg: Pharmacologic activities of the8-citrulline-analogues of oxytocin and vasopressin. Endocrinology 73, 637–639 (1963).

    Article  Google Scholar 

  • Van Eps, S.W.S., C.Ch.T.H. Romeny-Wachter, H. Schouten, and A.M. Strtjyker Bou-Dier: Renal concentration test in a tropical climate. Clin. chim. Acta 14, 637–644 (1966).

    Article  Google Scholar 

  • Verney, E.B.: Water diuresis. Irish J. med. Sci. 6, 377–402 (1954).

    Article  Google Scholar 

  • Vierling, A.F., J. B. Little, and E.P. Radford: Antidiuretic hormone bioassay in rats with heriditary hypothalamic diabetes insipidus (Brattleboro strain). Endocrinology 80, 211–220 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Vogel, G.: Daten zur Physiologie der Harnbereitung beim Truthuhn. Pflügers Arch. ges. Physiol. 278, 32–43 (1963).

    Google Scholar 

  • —, I. Stoeckert, W. Krüger, I. Dobberstein u. R. Winkler: Vergleichende Stop-Flow-Untersuchungen an Nieren mit geringem und wenig ausgebildetem System Henlescher Schleifen. Pflügers Arch. ges. Physiol. 238, 160–170 (1965a).

    Google Scholar 

  • —, u. I. Dobberstein: Harn und Harnbereitung bei terrestrisch lebenden Vögeln. Untersuchungen am Truthuhn (Meleagris pavo L.). Zbl. Vet.-Med. 12, 132–160 (1965b).

    Google Scholar 

  • — u. R. Winkler: Clearance und Stop-Flow-Untersuchungen an intakten und diabetes-insipidus-Ratten in Wasser-und osmotischer Diurese ohne und mit Zufuhr exogenen Vaso-pressins. Acta endocr. (Kbh.) 52, 239–254 (1966).

    CAS  Google Scholar 

  • Vorherr, H.: Über die Wirkung von synthetischem Oxytocin auf die Wasserdiurese der Ratte. Z. ges. exp. Med. 133, 602–608 (1960).

    Article  CAS  PubMed  Google Scholar 

  • —: Zur Frage des Oxytocin-Vasopressin-Antagonismus an der Diurèse bei Mensch und Tier. Klin. Wschr. 42, 198–201 (1964).

    Article  CAS  PubMed  Google Scholar 

  • Walker, A.M.: Experiments upon the relation between pituitary gland and water diuresis. Amer. J. Physiol. 127, 519–540 (1939).

    CAS  Google Scholar 

  • Ward, E.E., P. Richards, and O.H. Wrong: Urine concentration after acute renal failure. Nephron 3, 289–294 (1966).

    Article  CAS  PubMed  Google Scholar 

  • Weller, C. P.: On the mechanism of the refractoriness to ADH induced by water deprivation in the rat. Acta physiol. lat.-amer. 15, 411–416 (1965).

    CAS  PubMed  Google Scholar 

  • Weston, R.E., I.B. Hanenson, J. Grossman, G. A. Berdasco, and M. Wolfman: Natriuresis and chloruresis following pitressin-induced water retention in non-edematous patients: Evidence of homeostatic mechanism regulating body fluid volume. J. clin. Invest. 32,611–618 (1953).

    Google Scholar 

  • —, H.B. Horowitz, J. Grossman, I.B. Hanenson, and L. Leiter: Decreased antidiuretic response to betahypophamine in hyperthyroidism. J. clin. Endocr. 16, 322–337 (1956).

    Article  CAS  PubMed  Google Scholar 

  • White, A.G., G. Rubin, and L. Leiter: Studies in oedema. III. The effect of pitressin on the renal excretion of water and electrolytes in patients with and without liver disease. J. clin. Invest. 30, 1287–1297 (1951).

    Article  CAS  PubMed  Google Scholar 

  • White, H.L., and D. Rolf: Urine and papilla concentrations during transition from hypo-tonic to hypertonic urine. Amer. J. Physiol. 208, 397–400 (1965).

    CAS  PubMed  Google Scholar 

  • Whittembury, G., N. Sugino, and A.K. Solomon: Effect of antidiuretic hormone and calcium on the equivalent pore radius of kidney slices from necturus. Nature (Lond.) 187, 699–701 (1960).

    Article  CAS  Google Scholar 

  • Wiederholt, M.H. Stolte, J.P. Brecht u. K. Hierholzer: Mikropunktionsuntersuchungen über den Einfluß von Aldosteron, Cortison und Dexamethason auf die renale Natrium-résorption adrenalektomierter Ratten. Pflügers Arch. ges. Physiol. 292, 316–333 (1966).

    Article  CAS  Google Scholar 

  • Wirz, H.: Die Druckverhältnisse in der normalen Niere. Schweiz, med. Wschr. 86, 377–382 (1956).

    CAS  Google Scholar 

  • —: Kidney, water and electrolyte metabolism. Ann. Rev. Physiol. 23, 577–606 (1961).

    Article  CAS  Google Scholar 

  • Witte, E., H. Reineck u. O.H. Gatter: Antidiurese and Diurese nach kleinen Tonephingaben bei der Ratte abhängig vom oralen NaCl-Angebot. Pflügers Arch. ges. Physiol. 274, 262–271 (1961).

    Article  CAS  Google Scholar 

  • Wolgast, M.: Regional renal blood flow measured with P32-labelled red cells and beta-sensitive semiconductor detectors. Acta physiol. scand. 68, suppl. 277, 223 (1966).

    Google Scholar 

  • Yamsane, Y., and K. Kunishige: Bioassay of ADH on experimental diabetes insipidus rats with a study on the ADH level in normal human plasma. Jap. Circulat. J. (Enh.) 30, 1381–1386 (1966).

    Article  Google Scholar 

  • Yoon, M.C., and S.K. Hong: Effect of prolonged bodily hydration on the renal concentrating operation. J. appl. Physiol. 16, 815–818 (1961).

    CAS  PubMed  Google Scholar 

  • Yoshida, S., K. Motohashi, H. Ibayashi, and S. Okinaka: Method for the assay of anti-diuretic hormone in plasma with a note on the antidiuretic titer of human plasma. J. Lab. clin. Med. 62, 279–285 (1963).

    CAS  PubMed  Google Scholar 

  • Yunibhand, P., u. U. Held: Der Einfluß der zunehmenden Hydropenie auf Nierenmark, Serum und Urin bei Albinoratten. Helv. physiol. pharmakol. Acta 23, 139–144 (1965).

    CAS  Google Scholar 

  • Zain-Ttl-Abedin, M.: Effect of a single large vasopressin injection upon the chemical composition of kidney. J. Physiol. (Lond.) 181, 67p–68p (1965).

    Google Scholar 

  • Zaoral, M., E. Kasafirek, J. Rudinger, and F. Sorm: Amino acids and peptides. III. Synthesis of 2-O-Methyltyrosine-and 2-O-Ethyltyrosine-lysine-vasopressin. Collection Czech. Chem. Commun. 30, 1809–1873 (1965).

    Google Scholar 

  • —, J. Kolc, and F. Sorm: Synthesis of D-arg8-and D-lys8-vasopressin. Collection Czech. Chem. Commun. 31, 382–383 (1966).

    Article  CAS  Google Scholar 

  • —,: Amino acids and peptides LXX. Synthesis of D-Arg8-and D-lys8-vasopressin. Collection Czech. Chem. Commun. 32, 1242–1249 (1967a).

    Article  CAS  Google Scholar 

  • —: Amino acids and peptides Lxxi. Synthesis of l-deamino-8-D-aminobutyrine-vasopressin, l-deamino-8-D-lysine-vasopressin, and l-deamino-8-D-argine-vasopressin. Collection Czech. Chem. Commun. 32, 1250–1257 (1967b).

    Article  CAS  Google Scholar 

  • —, V. Pliska, K. Rezabek, and F. Sorm: Synthesis of a highly effective analogue of lysine-vasopressin. Collection Czech. Chem. Commun. 28, 746–747 (1963a).

    CAS  Google Scholar 

  • —, and F. Sorm: Synthesis of two lysine-vasopressin analogues with protracted hormonal activity. Collection Czech. Chem. Commun. 28, 747–749 (1963b).

    CAS  Google Scholar 

  • —, and F. Sorm: Amino acids and peptides. LX. Synthesis of D-DAB8-vasopressin. Collection Czech. Chem. Commun. 31, 310–314 (1966).

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1968 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Thorn, N.A. (1968). The Influence of the Neurohypophysial Hormones and Similar Polypeptides on the Kidneys. In: Berde, B. (eds) Neurohypophysial Hormones and Similar Polypeptides. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46127-9_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-46127-9_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46129-3

  • Online ISBN: 978-3-642-46127-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics