Skip to main content
SpringerLink
Log in

Neurohypophysis. Structure and Function

  • Chapter
Neurohypophysial Hormones and Similar Polypeptides

Abstract

In the customary sense, the neurohypophysis is the posterior lobe (neural lobe) of the hypophysis (Fig. 1) situated together with the main substance of the adeno-hypophysis in the pituitary fossa of the sphenoid bone. Actually the posterior lobe is only a part of that portion of the hypothalamus which is to be defined as the neurohypophysis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abrahams, V.C., and M. Pickford: Simultaneous observations on urine flow and uterine activity in the conscious bitch. J. Physiol. (Lond.) 12, 56 (1953).

    Google Scholar 

  • Acher, R.: Etat naturel des principes oxytocique et vasopressique de la neurohypophyse. II. Int. Symposium über Neurosekretion, Lund 1957, p. 71–78. Hrsg. von W. Bargmann, B. Hanström, B. U. E. Scharrer. Berlin-Göttingen-Heidelberg: Springer 1958.

    Google Scholar 

  • —: Biochemistry of the protein hormones. Ann. Rev. Biochem. 29, 547–576 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Anderson, B.: Some observations on the neurohormonal regulation of milk-ejection. Acta physiol. scand. 23, 1–7 (1951).

    Article  Google Scholar 

  • Anderson, E., and W. Haymaker: Elaboration of hormones by pituitary cells growing in vitro. Proc. Soc. exp. Biol. (N.Y.) 33, 313–316 (1935).

    CAS  Google Scholar 

  • Assenmacher, I., et J. Benoit: Quelques aspects du contrôle hypothalamique de la fonction gonadotrope de la préhypophyse. In: Pathophysiologia diencephalica, p. 401–426. Wien: Springer 1958.

    Google Scholar 

  • Barer, R., and K. Lederis: Ultrastructure of the rabbit neurohypophysis with special reference to the release of hormones. Z. Zeilforsch. 75, 201–239 (1966).

    Article  CAS  Google Scholar 

  • Bargmann, W.: Ãœber die neurosekretorische Verknüpfung von Hypothalamus und Neuro-hypophyse. Z. Zeilforsch. 34, 610–634 (1949).

    CAS  Google Scholar 

  • —: Ãœber das Zwischenhirn-Hypophysensystem von Fischen. Z. Zellforsch. 38, 275–298 (1953).

    Article  PubMed  CAS  Google Scholar 

  • —: Das Zwischenhirn-Hypophysensystem. Berlin-Göttingen-Heidelberg: Springer 1954.

    Book  Google Scholar 

  • —: Weitere Untersuchungen am neurosekretorischen Zwischenhirn-Hypophysensystem. Z. Zellforsch. 42, 247–272 (1955).

    Article  PubMed  CAS  Google Scholar 

  • —: Ãœber Synapsen im endokrinen System. Nova Acta Leopoldina N.F. 30, 199–206 (1965).

    Google Scholar 

  • —: Neurosecretion. Int. Rev. Cytol. 19, 183–201 (1966).

    Article  PubMed  CAS  Google Scholar 

  • —: Ãœber neuroendokrine Zwischenhirnsysteme. Freiburger Universitätsreden N.F. Heft 42. Freiburg/Br.: Hans Ferdinand Schulz 1967.

    Google Scholar 

  • —, u. A. Knoop: Ãœber die morphologischen Beziehungen des neurosekretorischen Zwischen-hirnsystems zum Zwischenlappen der Hypophyse (licht-und elektronenmikroskopische Untersuchungen). Z. Zellforsch. 52, 256–277 (1960).

    Article  PubMed  CAS  Google Scholar 

  • — u. A. Thiel: Elektronenmikroskopische Studie an der Neurohypophyse von Tropidono-tus natrix. Z. Zellforsch. 47, 114–126 (1957).

    Article  PubMed  CAS  Google Scholar 

  • —, u. E. Lindner: Ãœber den Feinbau des Nebennierenmarkes des Igels (Erinaceus europaeus L.). Z. Zellforsch. 64, 868–912 (1964).

    Article  PubMed  CAS  Google Scholar 

  • — u. K.H. Andres: Ãœber Synapsen an endokrinen Epithelzellen und die Definition sekretorischer Neurone. Untersuchungen am Zwischenlappen der Katzenhypophyse. Z. Zellforsch. 77, 282–298 (1967).

    Article  CAS  Google Scholar 

  • —, and E. Scharrer: The site of origin of the hormones of the posterior pituitary. Amer.Scientist 39, 255–259 (1951).

    Google Scholar 

  • Barry, L., et G. Cotte: Etude préliminaire, au microscope électronique, de l’éminence médiane du cobaye. Z. Zeilforsch. 53, 714–724 (1961).

    Article  CAS  Google Scholar 

  • Bennett, M. V.L., and S. Fox: Electrophysiology of caudal neurosecretory cells in the skate and fluke. Gen. comp. Endocr. 2, 77–96 (1962).

    Article  PubMed  CAS  Google Scholar 

  • Benoit, J.: The structural components of the hypothalamo-hypophyseal pathway, with particular reference to photostimulation of the gonads in birds. Ann. N.Y. Acad. Sci. 117, 23–34 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Berde, B.: Recent progress in oxytocin research. Springfield/Ill.: Charles C. Thomas 1959.

    Google Scholar 

  • Bern, H.A.: The properties of neurosecretory cells. Gen. comp. Endocr. Suppl. 1, 117–132 (1962).

    Article  Google Scholar 

  • —: On the production of hormones by neurons and the rôle of neurosecretion in neuroendocrine mechanisms. Symp. Soc. exp. Biol. 20, 325–344 (1966).

    PubMed  CAS  Google Scholar 

  • —, and R.S. Nishioka: Fine structure of the median eminence of some passerine birds. Proc. Zool. Soc. Calcutta 18, 107–119 (1965).

    Google Scholar 

  • —, L.R. Mewaldt, and D.S. Farner: Photoperiodic and osmotic influences on the ultra-structure of the hypothalamic neurosecretory system of the white-crowned sparrow (Zono-trichia leucophrys Gambelii). Z. Zellforsch. 69, 198–227 (1966).

    Article  PubMed  CAS  Google Scholar 

  • —, and K. Yagi: Electrophysiology of neurosecretory systems. Excerpta Med. Int. Congress Ser. No. 83, 577–583 (1964).

    Google Scholar 

  • Bie, P., and N.A. Thorn: Studies of the possible release of antidiuretic hormone from hypothalamic tissue in vitro. Acta physiol. scand. 68 (suppl. 277), 26 (1966).

    Google Scholar 

  • Bindler, E., FR. S. Labella, and M. Sanwal: Isolated nerve endings (neurosecretosomes) from the posterior pituitary. Partial separation of Vasopressin and Oxytocin and the isolation of microvesicles. Cell Biol. 34, 185–205 (1967).

    Article  CAS  Google Scholar 

  • Bodian, D.: Nerve endings, neurosecretory substance and lobular organization of the neurohypophysis. Bull. Johns Hopk. Hosp. 89, 354–376 (1951).

    CAS  Google Scholar 

  • —: Cytological aspects of neurosecretion in opossum neurohypophysis. Bull. Johns Hopk. Hosp. 113, 57–93 (1963).

    CAS  Google Scholar 

  • Breuer, H. A.: Untersuchungen über die Auswirkung des Hungers auf die postnatale Entwicklung der Regulationszentren des Wasserhaushaltes. Z. Kinderheilk. 96,308–321 (1966).

    Article  PubMed  Google Scholar 

  • Bucy, P.C.: The pars nervosa of the bovine hypophysis. J. comp. Neurol. 50, 505–520 (1930).

    Article  Google Scholar 

  • Campbell, D. J., and R.L. Holmes: Further studies on the neurohypophysis of the hedgehog (Erinaceus europaeus). Z. Zellforsch. 75, 35–46 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Clements, J.P., and T.P. Harrison: Variations in the distribution of the portal vessels of the rat’s hypophysis cerebri. Communic. Anat. Soc. of Great Britain and Ireland 1966, 36 (Ref. No. 44).

    Google Scholar 

  • Dahlström, Anntca: The intraneuronal distribution of noradrenaline and the transport and life-span of amine storage granules in the sympathetic adrenergic neuron. A histochemical and biochemical study. Stockholm 1966.

    Google Scholar 

  • Daniel, A.B., and K. Lederis: Release of neurohypophysial hormones in vitro. J. Physiol. (Lond.) 190, 171–187 (1967).

    CAS  Google Scholar 

  • Dawson, A.B.: Hypothalamo-hypophysial relationship in Rana pipiens demonstrated by Gomoris’ chromalum-hematoxylin method. Anat. Rec. 112, 443–444 (1952).

    Article  Google Scholar 

  • Diepen, R.: Der Hypothalamus. In: Handbuch der mikroskopischen Anatomie des Menschen, Bd. IV, S. 7. Hrsg. von W. Bargmann. Berlin-Göttingen-Heidelberg: Springer 1962.

    Google Scholar 

  • Dierickx, K., and A. Van Den Abeele: On the relations between the hypothalamus and the anterior pituitary in Rana temporaria. Z. Zellforsch. 51, 78–87 (1959).

    Article  PubMed  CAS  Google Scholar 

  • —: The nerve fibres controlling the gonadotropic activity of the hypophysis of Rana temporaria. Z. Zellforsch. 63, 938–949 (1964).

    Article  PubMed  CAS  Google Scholar 

  • —: Regeneration of the neural lobe of the hypophysis after extirpation of the median eminence in Rana temporaria. Acta anat. (Basel) 60, 181–186 (1965).

    Article  Google Scholar 

  • —: The origin of the aldehyde-fuchsin-negative nerve fibres of the median eminence of the hypophysis: a gonadotropic centre. Z. Zellforsch. 66, 504–518 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Eichner, D.: Zur Morphologie des neurosekretorischen hypothalamisch-hypophysären Systems beim Goldhamster (Cricetus auratus) unter normalen und experimentellen Bedingungen. Z. Zellforsch. 40, 151–161 (1954).

    Article  PubMed  CAS  Google Scholar 

  • Enemar, A., B. Falck, and F.C. Itttrriza: Adrenergic nerves in the pars intermedia of the pituitary in the toad (Bufo arenarum) Z. Zellforsch. 77, 325–330 (1967).

    Article  PubMed  CAS  Google Scholar 

  • Falck, B.: Cellular localization of monoamines. Progr. Brain Res. 8, 28–44 (1964).

    Article  CAS  Google Scholar 

  • Farner, D.S., A. Oksche, and L. Lorenzen: Hypothalamic neurosecretion and the photo-periodic testicular response in the white-crowned sparrow (Zonotrichia leucophrys gambelii). In: Proc. 3rd Int. Symposium on Neurosecretion, Bristol 1961.

    Google Scholar 

  • —: The photoperiodic control of reproduction cycles in birds. Amer. Scientist 52, 137–156 (1964).

    Google Scholar 

  • Ficq, A., and J. Flament-Durand: Autoradiography in endocrine research. In: Techniques in endocrine research, pp. 73–85. Ed. by P. Eckstein and FR. Knowles. New York: Academic Press 1963.

    Google Scholar 

  • Fujita, H., and J. FR. Hartmann: Electron microscopy of neurohypophysis in normal, adrenaline-treated and pilocarpine-treated rabbits. Z. Zellforsch. 54, 734–763 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Fujita, T.: Ãœber das Zwischenhirn-Hypophysensystem von Chimaera monstrosa. Z. Zellforsch. 60, 147–162 (1963).

    Article  PubMed  CAS  Google Scholar 

  • Fuxe, K.: Cellular localization of monoamines in the median eminence and the infundibular stem of some mammals. Z. Zellforsch. 61, 710–724 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Gabe, M.: Neurosecretion. Oxford-London-Edinburgh-New York-Toronto-Paris-Braun-schweig: Pergamon Press 1966.

    Google Scholar 

  • Gaupp, V., u. H. Spatz: Hypophysenstieldurchtrennung und Geschlechtsreifung. Ãœber Regenerationserscheinungen an der suprasellären Hypophyse. Acta neuroveg. (Wien) 12, 285–328 (1955).

    Article  CAS  Google Scholar 

  • Geiling, E.M.M., and M.R. Lewis: Further information regarding the melanophore hormone of the hypophysis cerebri. Amer. J. Physiol. 113, 534–537 (1935).

    Google Scholar 

  • Greving, R.: Beitrag zur Innervation der Hypophyse. Klin. Wschr. 4, 218 (1925).

    Article  Google Scholar 

  • Guillemin, R.: Hypothalamic-hypophysial interrelationships in the production of pituitary hormones in vitro. In: Hypothalamic-hypophysial interrelationships. Ed. by W.S. Fields. Springfield/Ill.: Charles C. Thomas 1956.

    Google Scholar 

  • —: Hypothalamic factors releasing pituitary hormones. Recent Progr. Hormone Res. 20, 89–121 (1964).

    PubMed  CAS  Google Scholar 

  • Hanström, B.: The hypophysis in some South African insectivora, Carnivora, Hyracoidea, Proboscidea, Artiodactyla and Primates. Arkiv. Zool. 4, 187–294 (1952).

    Google Scholar 

  • —: The neurohypophysis in the series of mammals. Z. Zellforsch. 39, 241–259 (1953).

    PubMed  Google Scholar 

  • Harris, G. W.: Neural control of the Pituitary gland. Monographs of the Physiological Society. London: Edward Arnold (Publishers) Ltd. 1955.

    Google Scholar 

  • —: Entwicklung und heutiger Stand der Neuroendokrinologie. Dtsch. med. Wschr. 90, 61–65 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Hild, W.: Experimentell-morphologische Untersuchungen über das Verhalten der „Neuro-sekretorischen Bahn“ nach Hypophysenstieldurchtrennungen, Eingriffen in den Wasserhaushalt mit Belastung der Osmoregulation. Virchows Arch. path. Anat. 319, 526–546 (1951).

    CAS  Google Scholar 

  • —: Elaboration of so-called posterior lobe hormones in the hypothalamus. Biol. Bull. 105, 360–361 (1953).

    Google Scholar 

  • —: Histological and endocrinological observations in tissue cultures of posterior pituitary of dog and rat. Tex. Rep. Biol. Med. 12, 474–488 (1954).

    PubMed  CAS  Google Scholar 

  • —: Das morphologische, kinetische und endokrinologische Verhalten von hypothalamischem und neurohypophysärem Gewebe in vitro. Z. Zellforsch. 40, 257–312 (1954).

    Article  PubMed  CAS  Google Scholar 

  • —, and G. Zetler: Ãœber das Vorkommen der Hypophysenhinterlappenhormone im Zwischenhirn. Arch. exp. Pathol. Pharmakol. 213, 139–153 (1951).

    Article  CAS  Google Scholar 

  • —: Vergleichende Untersuchungen über das Vorkommen der Hypophysenhinterlappenhormone im Zwischenhirn einiger Säugetiere. Dtsch. Z. Nervenheilk. 167, 205–214 (1952).

    CAS  Google Scholar 

  • —: Ãœber die Funktion des Neurosekrets im Zwischenhirn-Neurohypophysensystem als Trägersubstanz für Vasopressin, Adiuretin und Oxytocin. Z. ges. exp. Med. 120, 236–243 (1953).

    Article  PubMed  CAS  Google Scholar 

  • —: Experimenteller Beweis für die Entstehung der sog. Hypophyseiminterlappenwirkstoffe im Hypothalamus. Pflügers Arch. ges. Physiol. 257, 169–201 (1953).

    Article  CAS  Google Scholar 

  • Hökfelt, T.: The possible ultrastructural identification of tubero-infundibular dopamine-containing nerve endings in the median eminence of the rat. Brain Res. 5, 121–123 (1967).

    Article  PubMed  Google Scholar 

  • Holmes, R. L.: Comparative observations on inclusions in nerve fibres of the mammalian neurohypophysis. Z. Zellforsch. 64, 474–492 (1964).

    Article  PubMed  CAS  Google Scholar 

  • —: The fine structure of the infundibular process in the hedgehog. Z. Zellforsch. 61, 894–912 (1964).

    Article  Google Scholar 

  • Holzmann, K.: Die neurosekretorische Verknüpfung von Hypothalamus und Hypophyse bei Balaenoptera borealis. Z. Zellforsch. 51, 185–208 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Ittjrriza, F.C., and M.A. Restelli: Neurosecretion in the distal stump of the sectioned hypothalamic-hypophyseal tract in the toad. Z. Zellforsch. 81, 297–302 (1967).

    Article  Google Scholar 

  • Kivalo, J.: Effect of some anesthetic agents on diuresis and hypothalamo-hypophysial neurosecretion in the rat. Ann. Med. exp. Fenn. 44 (Suppl. No. 5).

    Google Scholar 

  • Knowles, F.R.: Neuroendocrine correlations at the level of ultrastructure. Arch. Anat. Micro-scop. Morphol. Exper. 54, 343–358 (1965).

    CAS  Google Scholar 

  • —, and L. Vollrath: Synaptic contacts between neurosecretory fibres and pituicytes in the pituitary of the eel. Nature (Lond.) 206, 1168–1169 (1965).

    Article  CAS  Google Scholar 

  • —: Neurosecretory innervation of the pituitary of the eels Anguilla and Conger. Proc. roy. Soc. 250, 311–342 (1966).

    Google Scholar 

  • —: Changes in the pituitary of the migrating european eel during its journey from rivers to the sea. Z. Zellforsch. 75, 317–327 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Kobayashi, H.: Histochemical, electron-microscopic and pharmacologic studies on the median eminence. Excerpta Med. Int. Congr. Ser. No. 83, 570–576 (1964).

    Google Scholar 

  • —, T. Hirano, and T. Matsui: Accumulation of aldehyde-fuchsin stainable material in the posterior median eminence following total hypophysectomy or adenohypophysectomy in the pigeon. J. Fac. Sci., Univ. Tokyo, Sec. IV, 11, 1–9 (1966).

    Google Scholar 

  • —, Y. Oota, H. Uemtjra, and T. Hirano: Electron-microscopic and pharmacological studies on the rat median eminence. Z. Zellforsch. 71, 387–404 (1966).

    Article  CAS  Google Scholar 

  • Kratzsch, E.: Experimentell-morphologische Untersuchungen am Zwischenhirn-Hypophysensystem der Ratte bei Polyurie infolge Alloxanvergiftung. (Mit besonderer Berücksichtigung der Pituicyten). Z. Zellforsch. 36, 371–380 (1951).

    PubMed  CAS  Google Scholar 

  • Lederis, K.: Ultrastructure of the hypothalamo-neurohypophysial system in teleost fishes and isolation of hormone-containing granules from the neurohypophysis of the cod (Gadusmorrhua). Z. Zellforsch. 58, 192–213 (1962).

    Article  PubMed  CAS  Google Scholar 

  • —: An electron-microscopical study of the human neurohypophysis. Z. Zellforsch. 65, 847–868 (1965).

    Article  PubMed  CAS  Google Scholar 

  • —: Acetylcholin in the mammalian neurohypophysis. J. Endocr. 37, 24–25 (1966).

    Google Scholar 

  • —: Beziehung zwischen der Ultrastruktur der Neurohypophyse und der subcellulären Verteilung von biologisch aktiven Substanzen. Naunyn-Schmiedebergs Arch. Path. Pharmak. 257, 83–93 (1967).

    Article  CAS  Google Scholar 

  • Legait, H., et E. Legait: Terminaisons neurosécrétoires au niveau de l’adénohypophyse chez quelques téléostéens. Etude au microscope électronique. C.R. Soc. Biol. (Paris) 151, 1943 à 1946 (1957).

    Google Scholar 

  • —: Recherches sur l’ultrastructure de l’hypophyse de quelques téléostéens. C.R. Soc. Biol. (Paris) 152, 130–133 (1958).

    Google Scholar 

  • — —,C. Btjrlet, et A. Burlet: Recherches histo-enzymologiques sur le système hypo-thalamo-neurohypophysaire du Lérot (Eliomys quercinus L.). Bull. Ass. Anat. 51. Réun. Marseille 1966.

    Google Scholar 

  • Malandra, B.: Beobachtungen am neurosekretorischen Zwischenhimsystem der normalen, trächtigen und laktierenden Ratte. Z. Zellforsch. 43, 594–610 (1956).

    PubMed  CAS  Google Scholar 

  • Matsui, T.: Fine structure of the median eminence of the rat. J. Fac. Sci. Univ. Tokyo, Sec. IV, 11, 71–96 (1966).

    Google Scholar 

  • —, and H. Kobayashi: Histochemical demonstration of monoamine oxidase in the hypo-thalamo-hypophysial system of the tree sparrow and the rat. Z. Zellforsch. 68, 172–182 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Mautner, W.: Das räumliche Bild des neurosekretorischen Zwischenhirnsystems und der por-talen Hypophysengefäße von Rana temporaria und einigen anderen Anuren. Mit Lebendbeobachtungen am portalen Hypophysenkreislauf. Z. Zellforsch. 64, 813–826 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Moll, J.: Regeneration of the supraoptico-hypophysial and paraventriculo-hypophysial tracts in the hypophysectomized rat. Z. Zellforsch. 46, 686–709 (1957).

    Article  PubMed  CAS  Google Scholar 

  • Monroe, Barbara G.: A comparative study on the ultrastructure of the median eminence, infundibular stem and neural lobe of the hypophysis of the rat. Z. Zellforsch. 76, 405–432 (1967).

    Article  PubMed  CAS  Google Scholar 

  • —, and D.E. Scott: Ultrastructural changes in the neural lobe of the hypophysis of the rat during lactation and suckling. J. Ultrastruct. Res. 14, 497–517 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Nowakowski, H.: Infundibulum und Tuber cinereum der Katze. Dtsch. Z. Nervenheilk. 165, 261–339 (1951).

    CAS  Google Scholar 

  • Oksche, A., D.S. Farner, D.L. Serventy, F. Wolff, and C. A. Nicholls: The hypothalamo-hypophysial neurosecretory system of the Zebra finch (Taeniopygia castanotis). Z. Zellforsch. 58, 846–914 (1963).

    Article  PubMed  CAS  Google Scholar 

  • D.L. Serventy, F. Wolff, and C. A. Nicholls —, D.F. Laws, F.I. Kamemoto, and D.S. Farner: The hypothalamo-hypophysial neurosecretory system of the white-crowned sparrow (Zonotrichia leucophrys Gambelii). Z. Zellforsch. 51, 1–42 (1959).

    Article  PubMed  CAS  Google Scholar 

  • D.L. Serventy, F. Wolff, and C. A. Nicholls —, W.O. Wilson, and D.S. Farner: The hypothalamic neurosecretory system of Coturnix coturnix japonica. Z. Zellforsch. 61, 688–709 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Oota, Y.: On the synaptic vesicles in the neurosecretory organs of the carp, bullfrog, pigeon and mouse. Annot. Zool. Jap. 36, 167–172 (1963).

    Google Scholar 

  • —, and H. Kobayashi: Fine structures of the median eminence and pars nervosa of the pigeon. Annot. Zool. Jap. 35, 128–138 (1962).

    Google Scholar 

  • —: Fine structure of the median eminence and the pars nervosa of the bullfrog (Rana catesbeiana). Z. Zellforsch. 60, 667–687 (1963).

    Article  PubMed  CAS  Google Scholar 

  • Ortmann, R.: Ãœber experimentelle Veränderungen der Morphologie des Hypophysen-Zwi-schenhirnsystems und die Beziehung der sog. „Gomorisubstanz“ zum Adiuretin. Z. Zellforsch. 36, 92–140 (1951).

    Article  PubMed  CAS  Google Scholar 

  • Pickford, M.: Control of the secretion of antidiuretic hormone from the pars nervosa of the pituitary gland. Physiol. Rev. 25, 573–595 (1945).

    PubMed  CAS  Google Scholar 

  • —: The action of acetylcholine in the supraoptic nucleus of the chloralosed dog. J. Physiol. (Lond.) 106, 264–270 (1947).

    CAS  Google Scholar 

  • Ranson, S.W., C. Fisher, and W.R. Ingram: The hypothalamico-hypophysial mechanism in diabetes insipidus. Res. Publ. Ass. nerv. ment. Dis. 17, 410–432 (1938).

    Google Scholar 

  • Rasmussen, A.T.: The weight of the principal components of the normal male adult human hypophysis cerebri. Amer. J. Anat. 42, 1–27 (1928).

    Article  Google Scholar 

  • —: The weight of the principal components of the normal hypophysis cerebri of the adult human female. Amer. J. Anat. 55, 253–275 (1934).

    Article  Google Scholar 

  • Rinne, U.K.: Ultrastructure of the median eminence of the rat. Z. Zellforsch. 74, 98–122 (1966).

    Article  PubMed  CAS  Google Scholar 

  • De Robertis, E.: Histophysiology of synapses and neurosecretion. Oxford-London-Edinburgh-New York-Paris-Frankfurt: Pergamon Press 1964.

    Google Scholar 

  • Rodeck, H., u. R. Braukmann: Zur Frage der Wirkung von Morphiumsulfat auf das neuro-sekretorische System. Z. Zellforsch. 75, 517–526 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Rodriguez, E.M.: Differences between median eminence and neural lobe in amphibians. Z. Zellforsch. 74, 308–316 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Romeis, B.: Die Hypophyse. In: Handbuch der mikroskopischen Anatomie des Menschen. Hrsg. von W. v. Möllendorff, Bd. VI, S. 3. Berlin: Springer 1940.

    Google Scholar 

  • Rothballer, A.B.: Changes in the rat neurohypophysis induced by painful stimuli with particular reference at neurosecretory material. Anat. Rec. 115, 23–36 (1953).

    Article  Google Scholar 

  • —: Pathways of secretion and regulation of posterior pituitary factors. Res. Publ. Ass. nerv, ment. Dis. 43, 86–131 (1966).

    CAS  Google Scholar 

  • Sarrat, R.: Modificaciones de la pars intermedia y posterior de la hipófisis producidas por el hambre y la sed. An. Anat. 16, 59–98 (1967).

    Google Scholar 

  • Scharrer, E.: Das Hypophysen-Zwischenhirnsystem von Scyllium stellare. Z. Zeilforsch. 37, 196–204 (1952).

    Article  CAS  Google Scholar 

  • —: Neurosecretion in the vertebrates: a survey. Publ. Staz. zool. Napoli 24 (Suppl.). Convegno sulla Neurosecrezione 1954, 18-20.

    Google Scholar 

  • —, u. B. Scharrer: Neurosekretion. In: Handbuch der mikroskopischen Anatomie des Menschen, Bd. VI, S. 5. Hrsg. von W. Bargmann. Berlin-Göttingen-Heidelberg: Springer 1954.

    Google Scholar 

  • Sloper, J.C., D. J. Arnott, and B.C. King: Sulphin metabolism in the pituitary and hypothalamus of the rat. A study of radioisotope-uptake after the injection of 35S O-L-Cysteine, Methionine, and sodium sulphate. J. Endocr. 20, 9–23 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Smoller, C. G.: Ultrastructural studies on the developing neurohypophysis of the Pacific tree-frog (Hyla regilla). Gen. comp. Endocr. 7, 44–73 (1966).

    Article  Google Scholar 

  • Spatz, H.: Neues über die Verknüpfung von Hypophyse und Hypothalamus. Acta neuroveg. (Wien) 3, 5–49 (1951).

    Article  CAS  Google Scholar 

  • Streefkerk, J. G.: Functional changes in the morphological appearance of the hypothalamo-hypophyseal neurosecretory and cholaminergic neural system, and in the adenohypophysis of the rat. Acad. Proefschrift, 1-110. Drukkerij W.G. van Soest N.V., Amsterdam 1967.

    Google Scholar 

  • Stutinsky, F.: Sur l’existence de cellules ganglionnaires dans la neurohypophyse de Boeuf. C.R. Soc. Biol. (Paris) 142, 63–65 (1948).

    CAS  Google Scholar 

  • —: La neurosécrétion au cours de la gestation et le post-partum chez la rate. Ann. Endocr. (Paris) 14, 722–725 (1953).

    CAS  Google Scholar 

  • —: Recherches morphologiques sur le complexe hypothalamo-neurohypophysaire. Bull. Micr. appl. Mémoire Lors série No. 2. Paris 1957.

    Google Scholar 

  • —, M. Bonvallet, and P. Dell: Les modifications hypophysaires au cours du diabète insipide expérimental chez le chien. I, IL Ann. Endocr. (Paris) 10, 505 (1949); 11, 1 (1950).

    Google Scholar 

  • Verney, E.B.: The antidiuretic hormone and the factors which determine its release. Proc. roy. Soc. B 135, 27–106 (1947).

    Article  Google Scholar 

  • Vitums, A., Sh.-L Mikamh, A. Oksche, and D. S. Farner: Vascularization of the hypothalamo-hypophysial complex in the white-crowned sparrow (Zonotrichia leucophrys Gambelii). Z. Zellforsch. 64, 541–569 (1964).

    Article  PubMed  CAS  Google Scholar 

  • A. Oksche, and D. S. Farner —, K. Ono, A. Oksche, D. S. Farner, and J. R. King: The development of the hypophysial portal system in the white-crowned sparrow (Zonotrichia leucophrys Gambelii) Z. Zellforsch. 73, 335–366 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Vollrath, L.: Ãœber die neurosekretorische Innervation der Adenohypophyse von Teleostiern, insbesondere von Hippocampus cuda und Tinca tinca. Z. Zellforsch. 78, 234–260 (1967).

    Article  PubMed  CAS  Google Scholar 

  • Wittkowski, W.: Synaptische Strukturen und Elementargranula in der Neurohypophyse des Meerschweinchens. Z. Zellforsch. 82, 434–458 (1967).

    Article  PubMed  CAS  Google Scholar 

  • Zambrano, D., and E. De Robertis: Ultrastructure of the hypothalamic neurosecretory system of the dog. Z. Zellforsch. 81, 264–282 (1967).

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. W. Bargmann
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Medizinisch-Biologische Forschungslaboratorien, Sandoz A.G., 4000, Basel, Switzerland

    B. Berde

Additional information

Dedicated to Professor Dr. Fritz Hahn (Freiburg/Br.) on his 60th birthday in friendship.

Rights and permissions

Reprints and permissions

Copyright information

© 1968 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bargmann, W. (1968). Neurohypophysis. Structure and Function. In: Berde, B. (eds) Neurohypophysial Hormones and Similar Polypeptides. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46127-9_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-46127-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46129-3

  • Online ISBN: 978-3-642-46127-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation