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Erythromycin and Oleandomycin

  • Chapter
Mechanism of Action

Part of the book series: Antibiotics ((ANTIBIOTICS,volume 1))

Abstract

Erythromycin (Fig. 1) is the most important member of a group of antibiotics known as macrolides. Structural characteristics of this group are 1. large lactone rings, 2. keto groups, and 3. amino sugars in glycosidic linkages. The mode of action of erythromycin has been subject to only relatively few studies which have, however, shown that the antibiotic is a specific inhibitor of protein synthesis. Reviews on erythromycin have been published by Forfar and Maccabe (1957) and by Grundy (1964).

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Authors
  1. F. E. Hahn
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Editors and Affiliations

  1. University of Illinois, Urbana, Illinois, USA

    David Gottlieb (Professor of Plant Pathology) & Paul D. Shaw (Associate Professor of Biochemistry) (Professor of Plant Pathology) &  (Associate Professor of Biochemistry)

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© 1967 Springer-Verlag Berlin · Heidelberg

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Hahn, F.E. (1967). Erythromycin and Oleandomycin. In: Gottlieb, D., Shaw, P.D. (eds) Mechanism of Action. Antibiotics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46051-7_26

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  • DOI: https://doi.org/10.1007/978-3-642-46051-7_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46053-1

  • Online ISBN: 978-3-642-46051-7

  • eBook Packages: Springer Book Archive

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