Abstract
Gougerotin was first isolated as a water soluble, basic antibiotic from culture filtrates of Streptomyces gougerotii, No. 21544 by workers at Takeda Chemical Industries, Ltd., Osaka, Japan (Kanzaki et al., 1962). Gougerotin was found to be a broad spectrum antibiotic of only limited commercial value due to its weak antibiotic activity and toxicity to mammalian systems (Table 1). The I.V. LD60 in mice is 57mg/kg.
Supported in part by United States Public Health Service Grant, GM 08647.
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Clark, J.M. (1967). Gougerotin. In: Gottlieb, D., Shaw, P.D. (eds) Mechanism of Action. Antibiotics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46051-7_20
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DOI: https://doi.org/10.1007/978-3-642-46051-7_20
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