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Substance-Induced Psychotic Symptoms

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Co-occurring Addictive and Psychiatric Disorders

Abstract

Psychosis can be brought on by a number of different substances such as alcohol, cannabis, sedatives, cocaine, stimulants, and hallucinogens. For some substances the psychosis is predominant in the acute phase (cannabis, cocaine, stimulants, and hallucinogens), but for others the withdrawal phase infers the heightened risk (alcohol and sedatives). Some drugs may also increase the risk of longer lasting psychotic disorders (cannabis and central stimulants), but it remains an area of dispute whether these drugs cause the primary psychosis or whether they precipitate psychosis in individuals who are already vulnerable. This chapter reviews the literature on this topic and gives advice on the treatment of acute and prolonged psychotic illness in relationship to drug use, including delirium tremens caused by withdrawal from alcohol or sedatives.

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References

  • Allen MH, Currier GW, Carpenter D et al (2005) The expert consensus guideline series. Treatment of behavioral emergencies 2005. J Psychiatr Pract 1(11 Suppl):5–108

    Article  Google Scholar 

  • Amato L, Minozzi S, Davoli M (2011) Efficacy and safety of pharmacological interventions for the treatment of the alcohol withdrawal syndrome. Cochrane Database of Systematic reviews. doi: 10.1002/14651858.CD008537.

    Google Scholar 

  • Andréasson S, Allebeck P, Engström A, Rydberg U (1987) Cannabis and schizophrenia. A longitudinal study of Swedish conscripts. Lancet 8574:1483–1486

    Article  Google Scholar 

  • Baldacchino A, Hughes Z, Kehoe M et al (2012) Cannabis psychosis: examining the evidence for a distinctive psychopathology in a systematic and narrative review. Am J Addict 21(Suppl 1):S88–S98

    PubMed  Google Scholar 

  • Bell DS (1965) Comparison of amphetamine psychosis and schizophrenia. Br J Psychiatry 111:701–707

    Article  CAS  PubMed  Google Scholar 

  • Bramness JG, Gundersen ØH, Guterstam J et al (2012) Amphetamine-induced psychosis–a separate diagnostic entity or primary psychosis triggered in the vulnerable? BMC Psychiatry 12:221

    Article  PubMed Central  PubMed  Google Scholar 

  • Caton CL, Drake RE, Hasin DS et al (2005) Differences between early-phase primary psychotic disorders with concurrent substance use and substance-induced psychoses. Arch Gen Psychiatry 62(2):137–145

    Article  PubMed  Google Scholar 

  • Cole J, Kando J (1993) Adverse behavioral events reported in patients taking alprazolam and other benzodiazepines. J Clin Psychiatry 54:49–61

    PubMed  Google Scholar 

  • Curran C, Byrappa N, McBride A (2004) Stimulant psychosis: systematic review. Br J Psychiatry 185:196–204

    Article  PubMed  Google Scholar 

  • Degenhardt HW, Lynskey M (2003) Testing hypotheses about the relationship between cannabis use and psychosis. Drug Alcohol Depend 71:37–48

    Article  PubMed  Google Scholar 

  • Grelotti DJ, Kanayama G, Pope HG Jr (2010) Remission of persistent methamphetamine-induced psychosis after electroconvulsive therapy: presentation of a case and review of the literature. Am J Psychiatry 167(1):17–23

    Article  PubMed  Google Scholar 

  • Hedges DW, Woon FL, Hoopes SP (2009) Caffeine-induced psychosis. CNS Spectr 14:127–129

    PubMed  Google Scholar 

  • Hickman M, Vickerman P, Macleod J et al (2009) If cannabis caused schizophrenia–how many cannabis users may need to be prevented in order to prevent one case of schizophrenia? England and Wales calculations. Addiction 104:1856–1861

    Article  PubMed  Google Scholar 

  • Johns A (2001) Psychiatric effects of cannabis. Br J Psychiatry 178:116–122

    Article  CAS  PubMed  Google Scholar 

  • Koskinen J, Löhönen J, Koponen H et al (2010) Rate of cannabis use disorders in clinical samples of patients with schizophrenia: a meta-analysis. Schizophr Bull 36(6):1115–1130

    Article  PubMed Central  PubMed  Google Scholar 

  • Leamon MH, Flower K, Salo RE et al (2010) Methamphetamine and paranoia: the methamphetamine experience questionnaire. Am J Addict 19(2):155–168

    Article  PubMed Central  PubMed  Google Scholar 

  • Leelahanaj T, Kongsakon R, Netrakom P (2005) A 4-week, double-blind comparison of olanzapine with haloperidol in the treatment of amphetamine psychosis. J Med Assoc Thai 88(Suppl 3):S43–S52

    PubMed  Google Scholar 

  • McIver C, McGregor C, Baigant M et al (2006) Guidelines for the medical management of patients with methamphetamine psychosis. Drug and Alcohol Services, South Australia

    Google Scholar 

  • Medhus S, Mordal J, Holm B et al (2013) A comparison of symptoms and drug use between patients with methamphetamine associated psychoses and patients diagnosed with schizophrenia in two acute psychiatric wards. Psychiatry Res 206:17–21

    Article  PubMed  Google Scholar 

  • Moore TH, Zammit S, Lingford-Hughes A et al (2007) Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet 370:319–328

    Article  PubMed  Google Scholar 

  • Núñez LA, Gurpegui M (2002) Cannabis-induced psychosis: a cross-sectional comparison with acute schizophrenia. Acta Psychiatr Scand 105(3):173–178

    Article  PubMed  Google Scholar 

  • Shoptaw SJ, Kao U, Ling W (2009) Treatment for amphetamine psychosis. Cochrane Database Syst Rev (1):CD003026

    Google Scholar 

  • Srisurapanont M, Arunpongpaisal S, Wada K et al (2011) Comparisons of methamphetamine psychotic and schizophrenic symptoms: a differential item functioning analysis. Prog Neuropsychopharmacol Biol Psychiatry 35(4):959–964

    Article  CAS  PubMed  Google Scholar 

  • Stone JM, Fisher HL, Major B et al (2013) Cannabis use and first-episode psychosis: relationship with manic and psychotic symptoms, and with age at presentation. Psychol Med 24:1–8

    Google Scholar 

  • Sullivan JT, Sykora K, Schneiderman J et al (1989) Assessment of Alcohol Withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). Br J Addict 84(11):1353–1357

    Article  CAS  PubMed  Google Scholar 

  • Ujike H, Sato M (2004) Clinical features of sensitization to methamphetamine observed in patients with methamphetamine dependence and psychosis. Ann N Y Acad Sci 1025:279–287

    Article  CAS  PubMed  Google Scholar 

  • Yeh HS, Lee YC, Sun HJ, Wan SR (2001) Six months follow-up of patients with methamphetamine psychosis. Zhonghua Yi Xue Za Zhi (Taipei) 64:388–394

    CAS  Google Scholar 

  • Zammit S, Allebeck P, Andreasson S et al (2002) Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study. BMJ 325:1199

    Article  PubMed Central  PubMed  Google Scholar 

  • Zuardi AW, Crippa JA, Hallak JE et al (2012) A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation. Curr Pharm Des 18:5131–5140

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Jørgen G. Bramness .

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Bramness, J.G., Franck, J. (2015). Substance-Induced Psychotic Symptoms. In: Dom, G., Moggi, F. (eds) Co-occurring Addictive and Psychiatric Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45375-5_7

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  • DOI: https://doi.org/10.1007/978-3-642-45375-5_7

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45374-8

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