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7 Genomics and Transcriptomics to Analyze Fruiting Body Development

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Part of the book series: The Mycota ((MYCOTA,volume 13))

Abstract

Many filamentous ascomycetes and basidiomycetes produce fruiting bodies for the protection and dispersal of sexual spores. The genetic control of this developmental process has been studied for several decades, but only recently advances in high-throughput techniques have made possible analyses of genes and their expression at a genome-wide scale. This includes the sequencing of fungal genomes, microarrays for filamentous fungi, the development of efficient gene deletion strategies, and the application of next-generation sequencing to address questions of fungal biology. These methods and resources have been used to learn more about fruiting body differentiation, for example, to identify genes that are involved in this process and to understand the coordinated patterns of gene expression that underlie developmental events. This review gives an overview of how genomics and transcriptomics were used to analyze the molecular basis that governs the transitions from vegetative mycelium to mature fruiting body.

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Acknowledgments

I would like to thank Prof. Dr. Ulrich Kück for his support and Dr. Sandra Bloemendal for critical reading of the manuscript. Funding for my work comes from the German Science Foundation (Deutsche Forschungsgemeinschaft, DFG, grant no. NO 407/2-1) and the Protein Research Department of Ruhr-University Bochum.

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Nowrousian, M. (2014). 7 Genomics and Transcriptomics to Analyze Fruiting Body Development. In: Nowrousian, M. (eds) Fungal Genomics. The Mycota, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45218-5_7

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