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Fat Grafting Supplemented by Adipose-Derived Stem Cells for Breast Augmentation

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Stem Cells in Aesthetic Procedures

Abstract

Recent advances in the sophistication of grafting procedures and the understanding of the biology of adipose tissue have enabled the development of autologous fat grafting to the breast for cosmetic augmentation. Additionally, supplementing the graft materials with adipose-derived stem cells, isolated through liposuction, has been reported to be beneficial for enhancing graft retention. Despite the potential benefits of the technique, concerns have been raised including donor site morbidity and the obstruction of breast cancer detection, particularly for high-risk patients. The efficacy of the technique also needs further investigation. Multicenter, randomized clinical trials are recommended to ensure that fat grafting with or without adipose-derived stem cells is a safe, effective, and evidence-based procedure for breast augmentation.

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Author information

Authors and Affiliations

  1. Department of Plastic and Reconstructive Surgery, Nippon Medical School, 2-1-1 Hongo Bunkyo-ku, Tokyo, 1138421, Japan

    Hiroshi Mizuno M.D., Ph.D.

  2. Department of Plastic and Reconstructive Surgery, Nippon Medical School, 1-1-5 Sendagi Bunkyo-ku, Tokyo, 1138603, Japan

    Hiko Hyakusoku M.D., Ph.D.

Authors
  1. Hiroshi Mizuno M.D., Ph.D.
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  2. Hiko Hyakusoku M.D., Ph.D.
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Corresponding author

Correspondence to Hiroshi Mizuno M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Section of Surgery, Newport Specialty Hospital, Tustin, California, USA

    Melvin A. Shiffman

  2. Department of Plastic and Reconstructive Surgery, Marche Polytechnic University Medical School, University of Ancona, Ancona, Italy

    Alberto Di Giuseppe

  3. Department of Plastic Surgery, University of Padova, Padova, Italy

    Franco Bassetto

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Mizuno, H., Hyakusoku, H. (2014). Fat Grafting Supplemented by Adipose-Derived Stem Cells for Breast Augmentation. In: Shiffman, M., Di Giuseppe, A., Bassetto, F. (eds) Stem Cells in Aesthetic Procedures. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45207-9_36

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  • DOI: https://doi.org/10.1007/978-3-642-45207-9_36

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