Future Directions for the Treatment of Dentin Hypersensitivity

  • Agata Czajka-JakubowskaEmail author
  • Brian H. Clarkson


There are over 30 different treatments for sensitive dentin on the market today which suggests that not one of them gives the immediate and lasting relief from this condition desired by the patient. In this chapter we describe several, emerging, novel experimental technologies that may, in the future, offer such relief. These technologies include: a synthetic “glue” resembling the adhesive that adheres mollusks to rocks in the ocean; a self-etch resin filled with fluorhydroxyapatite (FA) crystrals; and a flexible laminate of Eudragit filled with the FA srystals. Finally the incorporation of dendrimers (artificial proteins) functionalized with anti-inflammatories and anti-microbials to control inflammation beneath sensitive dentin and, overtime, help the pulp repair.


Mineralized Layer Dentinal Tubule Moist Condition Dentin Surface Dentin Hypersensitivity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Tooth desensitizing. Retrieved from Accessed 1 April 2013
  2. Chang S, Chen H, Liu J, Wood D, Bentley P, Clarkson B (2006) Synthesis of a potentially bioactive hydroxyapatite nucleating molecule. Calcif Tissue Int 78(1):51–61CrossRefGoogle Scholar
  3. Chen H, Tang Z, Liu J, Sun K, Chang S-R, Peters T, Czajka-Jakubowska A, Clarkson B (2006) Acellular synthesis of a human-like microstructure. Adv Mater 18(14):1846–1851CrossRefGoogle Scholar
  4. Duran I, Sengun A (2004) The long term effect of 5 current desensitising products on cervical dentine sensitivity. J Oral Rehabil 31:351–356PubMedCrossRefGoogle Scholar
  5. Ferracane J (2011) Resin composite-state of the art. Dent Mater 27(1):29–38PubMedCrossRefGoogle Scholar
  6. Narungdej T, Sakoolnamarka R, Booroung T (2010) The effectiveness of a calcium phosphosilicate desensitizer in reducing cervical dentin hypersensitivity. J Am Dent Assoc 141:995–999Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Maxillofacial Orthopaedics and OrthodonticsPoznan University of Medical SciencesPoznanPoland
  2. 2.Department of Cariology, Restorative Sciences and EndodonticsUniversity of Michigan School of DentistryAnn ArborUSA

Personalised recommendations