“How Can Sensitive Dentin Become Hypersensitive?”

  • David H. PashleyEmail author


When dentinal tubules first become exposed, patients note that those areas become more sensitive to tactile, evaporative, and osmotic stimuli. However, over time, especially with poor plaque control, those areas become progressively truly hypersensitive. There are a number of mechanisms responsible for hypersensitivity including localized pulpal inflammation, sprouting of pulpal nerves, and expression of “inflammatory” sodium channels. Often such hypersensitivity spontaneously disappears. These protective mechanisms will be reviewed. The problem arises for patients whose exposed dentin becomes hypersensitive and whose endogenous protective mechanism fails to correct the hypersensitivity.


Bacterial Plaque Dentinal Tubule Smear Layer Calcium Oxalate Crystal Dentin Hypersensitivity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported, in part, by R01 DE015306 from the NIDCR to DHP (PI) and by the King Abdulazziz University School of Dentistry to Prof. Pashley as their Hi-Ci dental scholar.


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© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Oral BiologyCollege of Dental Medicine, Georgia Regents UniversityAugustaUSA

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