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Clinical Manifestations of Chronic Radiation Syndrome

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Chronic Radiation Syndrome

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Abstract

In residents of the Techa riverside villages CRS cases of low degree of severity prevailed numerically. Several periods could be clearly distinguished in the course of the disease: latency period (as a rule, it made up 4-5 years); formation period (coincided in time with the period of the maximum radiation exposure); recovery period (could last for many years); and the period of late effects. CRS clinical picture in the formation period is characterized by multi-organ manifestations (inhibition of hematopoiesis and immunity, neurological disorders, disorders of the cardiovascular, digestive, endocrine and other systems). But the major manifestations of the syndrome were represented by changes in the hematopoietic and nervous systems. The recovery period starts 3-12 months after the termination of exposure or significant reduction in the dose rate. Over this period, reparation processes prevailed. The status of different organs in CRS persons in late periods is described.

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Notes

  1. 1.

    Here and hereafter in this book: the group “persons with CRS” comprised residents of the Techa riverside villages who were initially diagnosed with CRS; the group “exposed persons without CRS” was composed of Techa riverside residents who had not developed manifestations of CRS.

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  1. Clinical Department, Urals Research Centre for Radiation Medicine, Chelyabinsk, Russia

    Alexander V. Akleyev MD, PhD

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  1. Alexander V. Akleyev MD, PhD
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Akleyev, A.V. (2014). Clinical Manifestations of Chronic Radiation Syndrome. In: Chronic Radiation Syndrome. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45117-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-45117-1_5

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  • Print ISBN: 978-3-642-45116-4

  • Online ISBN: 978-3-642-45117-1

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