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Quantum Dot-Fluorescence-Based Biosensing

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Quantum Dots for DNA Biosensing

Part of the book series: SpringerBriefs in Molecular Science ((BRIEFSMOLECULAR))

Abstract

Since the emergence of quantum dots (QDs), their excellent fluorescent properties have been widely used in the fabrication of biological sensors for various analytes, such as metal ions, environmental samples, protein, deoxyribonucleic acid (DNA), and ribonucleic acid (RNA). More importantly, some of these sensors can realize not only fixed cell labeling, imaging of live cell dynamics, in situ tissue profiling, but also in vivo animal imaging. A lot of reviews have well summarized these in vitro diagnostic applications and in vivo imaging and sensing applications of QDs. In this chapter, we mainly focus on QDs-fluorescence-based biosensing in DNA, RNA, and DNA microarrays. The introduction of QDs in this aspect promoted the sensitivity, stability, and diversity of DNA and RNA detection obviously.

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, People’s Republic of China

    Jun-Jie Zhu & Fang-Fang Cheng

  2. School of Medical Imaging, Xuzhou Medical College, Xuzhou, 221004, People’s Republic of China

    Jing-Jing Li

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  1. Jun-Jie Zhu
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  2. Jing-Jing Li
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  3. Fang-Fang Cheng
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Correspondence to Jun-Jie Zhu .

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Zhu, JJ., Li, JJ., Cheng, FF. (2013). Quantum Dot-Fluorescence-Based Biosensing. In: Quantum Dots for DNA Biosensing. SpringerBriefs in Molecular Science. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-44910-9_3

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