Zusammenfassung
Arzneimittelinduzierte Leberschäden („drug-induced liver injury“, DILI) bezeichnen alle durch Medikamente verursachten Schädigungen der Leber. Es schließt sowohl frei verkäufliche als auch rezeptpflichtige Medikamente ein. Die Leberschädigung kann hoch akut oder mit zeitlichem Abstand von einigen Wochen nach Einnahme eintreten. Die Schädigungen können von leichter und reversibler bis tödlicher Ausprägung sein. Da das Erkennen einer arzneimittelinduzierten Leberschädigung aufgrund des unspezifischen Beschwerdebildes und der zeitlichen Latenz sehr schwierig ist, ist ein hohes Maß an klinischer Aufmerksamkeit zur Diagnosestellung erforderlich.
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zu Siederdissen, C., Cornberg, M. (2016). Arzneimittelinduzierte Leberschäden. In: Manns, M., Schneidewind, S. (eds) Praxis der Hepatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41620-0_18
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DOI: https://doi.org/10.1007/978-3-642-41620-0_18
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