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Epithelial Proliferative Lesions

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Benign Breast Diseases

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Abstract

The normal breast tissue consists of branching ducts, which terminate into the secretory lobular units. The ducts and lobules are lined by two layers of epithelium consisting of the inner secretory epithelial layer and the outer myoepithelial layer. An increase in the number of epithelial cells, three to four cells above the basement membrane, without bridging or distension of the lumina, indicates mild epithelial hyperplasia (Fitzgibbons et al. 1998). Mild epithelial hyperplasia is not associated with increased risk of malignancy (Rogers 1987). This pattern of mild epithelial proliferation is present in most specimens excised for benign and malignant breast tissue.

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Authors and Affiliations

  1. Princess Elizabeth Hospital Le Vauquiedor St. Martin’s Guernsey, Channel Islands, UK

    Catherine N. Chinyama MBChB(Hons),FRCPath,IFCAP,LLM (Consultant Pathologist, Honorary Clinical Senior Lecturer)

  2. Brighton and Sussex Medical School, Brighton, England UK

    Catherine N. Chinyama MBChB(Hons),FRCPath,IFCAP,LLM (Consultant Pathologist, Honorary Clinical Senior Lecturer)

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  1. Catherine N. Chinyama MBChB(Hons),FRCPath,IFCAP,LLM
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Chinyama, C.N. (2014). Epithelial Proliferative Lesions. In: Benign Breast Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41065-9_10

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  • DOI: https://doi.org/10.1007/978-3-642-41065-9_10

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