Abstract
This research presents multipath planning scheme for drug loaded nano carriers (virtual robots) based targeted drug delivery. Initially, magnetic field based local path planner algorithm is investigated for its viability within CNS (Central Nervous System) brain capillaries. Furthermore, Optimized Swarm based technologies in hybrid with the local path planner is applied to deal with the complexity of the neuronal blood capillaries system. Globally optimized swarm trajectories for the nano carriers to target multiple neuro-invasive diseases are obtained as a result from the proposed approach. For demonstration purpose the presented scheme is simulated in a 3d virtual environment, results showed that the optimized swarming was successfully performed in closer to real-time (online). Moreover, the drug delivery performance of the carrier robots was more targeted (directional path) and shorter in length and in uniform velocity keeping the overall drug release time controlled than the conventional (oral \ intravenous) drug delivery procedures.
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Hassan, S., Ullah, I., Kim, M.O., Yoon, J. (2013). Neuro Invasive Multi-targeted Drug Delivery Approach Using Swarm of Nano-robotic Carriers. In: Lee, J., Lee, M.C., Liu, H., Ryu, JH. (eds) Intelligent Robotics and Applications. ICIRA 2013. Lecture Notes in Computer Science(), vol 8102. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40852-6_22
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DOI: https://doi.org/10.1007/978-3-642-40852-6_22
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