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International Conference on Intelligent Robotics and Applications

ICIRA 2013: Intelligent Robotics and Applications pp 204–215Cite as

Neuro Invasive Multi-targeted Drug Delivery Approach Using Swarm of Nano-robotic Carriers

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Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 8102))

Abstract

This research presents multipath planning scheme for drug loaded nano carriers (virtual robots) based targeted drug delivery. Initially, magnetic field based local path planner algorithm is investigated for its viability within CNS (Central Nervous System) brain capillaries. Furthermore, Optimized Swarm based technologies in hybrid with the local path planner is applied to deal with the complexity of the neuronal blood capillaries system. Globally optimized swarm trajectories for the nano carriers to target multiple neuro-invasive diseases are obtained as a result from the proposed approach. For demonstration purpose the presented scheme is simulated in a 3d virtual environment, results showed that the optimized swarming was successfully performed in closer to real-time (online). Moreover, the drug delivery performance of the carrier robots was more targeted (directional path) and shorter in length and in uniform velocity keeping the overall drug release time controlled than the conventional (oral \ intravenous) drug delivery procedures.

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Author information

Authors and Affiliations

  1. School of Mechanical and Aerospace Engineering & ReCAPT, Gyeongsang National University, 660701, Jinju, Korea

    Syed Hassan & Jungwon Yoon

  2. College of Natural Sciences (RINS) and Applied Life Sciences, Gyeongsang National University, 660701, Jinju, Korea

    Ikram Ullah & Myeong Ok Kim

Authors
  1. Syed Hassan
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  2. Ikram Ullah
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  3. Myeong Ok Kim
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  4. Jungwon Yoon
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Editor information

Editors and Affiliations

  1. Department of Electrical Engineering, Pusan National University, South Korea

    Jangmyung Lee

  2. School of Mechanical Engineering, Pusan National University, Busan, South Korea

    Min Cheol Lee

  3. Intelligent Systems & Biomedical Robotics Group, School of Creative Technologies, University of Portsmouth, PO1 2DJ, England, UK

    Honghai Liu

  4. School of Mechanical Engineering, Biorobotics Laboratory, Korea University of Technology and Education, Gajeon-ri Byeongcheon-myeon 307, 330-708, Cheonan, Korea

    Jee-Hwan Ryu

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© 2013 Springer-Verlag Berlin Heidelberg

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Hassan, S., Ullah, I., Kim, M.O., Yoon, J. (2013). Neuro Invasive Multi-targeted Drug Delivery Approach Using Swarm of Nano-robotic Carriers. In: Lee, J., Lee, M.C., Liu, H., Ryu, JH. (eds) Intelligent Robotics and Applications. ICIRA 2013. Lecture Notes in Computer Science(), vol 8102. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40852-6_22

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  • DOI: https://doi.org/10.1007/978-3-642-40852-6_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-40851-9

  • Online ISBN: 978-3-642-40852-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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