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PET/MR in Brain Imaging

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PET/MRI

Abstract

The new hybrid PET/MR systems permit optimal spatial and temporal coregistration of structural, functional, and molecular data. The real-time high-resolution multiparametric imaging improves the clinical evaluation of disorders of the brain and offers new options for research in the central nervous system. This review discusses the advantages of integrated PET/MR for brain imaging and indicates possible applications in dementia, degenerative disorders, epilepsy, brain tumors, cerebrovascular disease, and inflammatory diseases. The integrated assessment of various parameters additionally will improve partial volume correction of metabolic and functional values and facilitate the modeling of dynamic data. PET/MR may also help to understand complex metabolic processes and permit insight into functional and structural connectivity in the brain. The multiple noninvasive investigative approaches offered simultaneously by PET/MR might gain a special impact in translational brain research.

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Acknowledgment

WDH has been supported by the Max Planck Society and by the WDH Foundation. AD has been supported by the DFG (Deutsche Forschungsgemeinschaft, Großgeräteinitiative), who funded the installation of the PET/MR scanner at the Technische Universität München. The scanner is operated by a consortium of the Departments of Nuclear Medicine and Radiology of the Technische Universität München, Munich, and of the Ludwig-Maximilians-Universität München, Munich. Furthermore, this work was supported by grants of the DFG [DR 445/3-1, 4-1 to A.D.]

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Authors and Affiliations

  1. Max Planck Institute for Neurological Research, Gleueler Str. 50, 50931, Köln, Germany

    Wolf-Dieter Heiss

  2. Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany

    Alexander Drzezga

Authors
  1. Wolf-Dieter Heiss
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  2. Alexander Drzezga
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Correspondence to Wolf-Dieter Heiss .

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Editors and Affiliations

  1. Depto. Medicina Nuclear, Autonomous University of Barcelona Hospital Sant Pau, Barcelona, Spain

    Ignasi Carrio

  2. Department of Radiology, University Hospitals Case Medical Center, Cleveland, Ohio, USA

    Pablo Ros

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Heiss, WD., Drzezga, A. (2014). PET/MR in Brain Imaging. In: Carrio, I., Ros, P. (eds) PET/MRI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40692-8_8

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  • DOI: https://doi.org/10.1007/978-3-642-40692-8_8

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  • Print ISBN: 978-3-642-40691-1

  • Online ISBN: 978-3-642-40692-8

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