Abstract
Positron Emission Tomography (PET) has been in clinical practice since early 1990s; however, widespread use was hampered due to non-availability of anatomical reference. In the late 1990s and early 2000s, with the advent of hybrid imaging, PET/computed tomography (CT), the oncological utilization has increased significantly. PET/CT has been shown to have high sensitivity and negative predictive value for the detection of tumors, with many studies reporting superior utility of PET/CT over conventional anatomical imaging such as CT, magnetic resonance imaging (MRI), and ultrasound. Despite limited literature regarding utilization of PET/CT in gall bladder and biliary tract cancer, the available literature studies provide evidence for the potential advantage of PET/CT in staging, restaging, and detecting recurrence of gallbladder and biliary tract cancer.
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References
Bailey D, Townsend PE, Valk MN (2005) Positron emission tomography: basic sciences 2005. Springer, Secaucus
Wood K, Hoskin PJ, Saunders MI (2007) Positron emission tomography in oncology: a review. Clin Oncol 19:237–255
Beuthien-Baumann B, Hamacher K, Oberdorfer F et al (2000) Preparation of fluorine-18 labelled sugars and derivatives and their application as tracer for positron-emission-tomography. Carbohydr Res 327(1–2):107–118
Warburg O, Wind F, Negelein E (1927) The metabolism of tumors in the body. J Gen Physiol 8(6):519–530
Kumar R, Halanaik D, Malhotra A (2010) Clinical applications of positron emission tomography-computed tomography in oncology. Indian J Cancer 47:100–119
Anderson H, Price P (2000) What does positron emission tomography offer oncology? Eur J Cancer 36:2028–2035
Lucignani G, Paganelli G, Bombardieri E (2004) The use of standardized uptake values for assessing FDG uptake with PET in oncology: a clinical perspective. Nucl Med Commun 25:651–656
Wahl R, Jacene H, Kasamon Y et al (2009) From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors. J Nucl Med 50(Suppl 1):122S–150S
Vriens D, Visser EP, Geus-Oei LF et al (2010) Methodological considerations in quantification of oncological FDG PET studies. Eur J Nucl Med Mol Imaging 37(7):1408–1425
Lee S, Kim HJ, Park JH (2010) Clinical usefulness of 18F-FDG PET-CT for patients with gallbladder cancer and cholangiocarcinoma. J Gastroenterol 45:560–566
Rodrigues-Fernandez A, Gomez-Rio M, Llamas-Elvira JM et al (2004) Positron-emission tomography with fluorine-18F-FDG for gallbladder cancer diagnosis. Am J Surg 188:171–175
Petrowsky H, Wildbrett P, Husarik DB et al (2006) Impact of integrated positron emission tomography and computed tomography on staging and management of gallbladder cancer and cholangiocarcinoma. J Hepatol 45:43–50
Yamada I, Ajiki T, Ueno K et al (2012) Feasibility of 18F-FDG PET for preoperative evaluation of biliary tract cancer. Anticancer Res 32(11):5105–5110
Shukla P, Barreto SG, Arya S et al (2008) Does PET-CT scan have a role prior to radical re-resection for incidental gallbladder cancer? HPB 10:439–445
Breitenstein S, Aperstegui C, Clavien PA (2008) Positron emission tomography (PET) for cholangiocarcinoma. HPB 10:120–121
Alkhawaldeh K, Faltten S, Biersack HJ et al (2011) The value of F-18 FDG PET in patients with primary sclerosing cholangitis and cholangiocarcinoma using visual and semiquantitative analysis. Clin Nucl Med 36(10):879–883
Corvera C, Blumgart LH, Akhurst T et al (2008) 18F-FDG PET influences management decisions in patients with biliary cancer. J Am Coll Surg 206:57–65
Kim J, Kim MH, Lee TY et al (2008) Clinical role of 18F-FDG PET-CT in suspected and potentially operable cholangiocarcinoma: a prospective study compared with conventional imaging. Am J Gastroenterol 103:1145–1151
Li J, Kuehl H, Grabellus F et al (2008) Preoperative assessment of hilar cholangiocarcinoma by dual-modality PET/CT. J Surg Oncol 98:438–443
Ruys A, Bennink RJ, van Westreenen HL et al (2011) FDG-positron emission tomography/computed tomography and standardized uptake value in the primary diagnosis and staging of hilar cholangiocarcinoma. HPB 134:256–262
Kobayashi S, Nagano H, Hoshino H et al (2011) Diagnostic value of FDG-PET for lymph node metastasis and outcome of surgery for biliary cancer. J Surg Oncol 103(3):223–229
Cameron K, Golan S, Simpson W et al (2011) Recurrent pancreatic carcinoma and cholangiocarcinoma: 18F-FDG PET/CT. Abdom Imaging 36(4):463–471
Kitajima K, Murakami K, Kanagae K (2009) Clinical impact of whole body FDG-PET for recurrent biliary cancer: a multicenter study. Ann Nucl Med 23:709–715
Kumar R, Sharma P, Kumari A et al (2012) Role of 18F-FDG PET/CT in detecting recurrent gallbladder carcinoma. Clin Nucl Med 37(5):431–435
Jadvar H, Henderson RW, Conti PS (2007) 18F-FDG PET and PET:CT in recurrent and metastatic cholangiocarcinoma. J Comput Assist Tomogr 31(2):223–228
Lee Y, Han SW, Oh DY et al (2011) Diagnostic performance of contrast enhanced CT and 18F-FDG PET/CT in suspicious recurrence of biliary tract cancer after curative resection. BMC 11(1):188–195
Smith G, Carroll L, Aboagye EO (2012) New frontiers in the design and synthesis of imaging probes for PET oncology: current challenges and future directions. Mol Imaging Biol 14(6):653–666
Yankeelov T, Pererson TE, Abramson RG et al (2012) Simultaneous PET-MRI in oncology: a solution looking for a problem? Magn Reson Imaging 30:1342–1356
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Chaudhry, M.A., Kadhim, L.AR., Wahl, R.L. (2014). Functional Imaging. In: Herman, J., Pawlik, T., Thomas, Jr., C. (eds) Biliary Tract and Gallbladder Cancer. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40558-7_11
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DOI: https://doi.org/10.1007/978-3-642-40558-7_11
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