Abstract
High-intensity focused ultrasound (HIFU) is an emerging noninvasive, local treatment for prostate cancer with 17 years of clinical experience during which approximately 50,000 HIFU treatments have been performed worldwide. The premise behind HIFU is the destruction of tissue by depositing large amounts of energy into it. Ultrasound waves deposit energy as they travel through tissue, but the amount of energy deposited during traditional, diagnostic ultrasound imaging is insignificant (Woodward and Warwick 1970). Ablating with ultrasound is accomplished by doing two things: increasing the intensity of the waves and focusing the waves on a focal point. When performed appropriately, it will raise the temperature of tissue to a level sufficient to cause irreversible damage (cell kill) in a discrete volume of tissue (Wu et al. 2001).
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Rewcastle, J.C., Gill, I.S. (2014). High-Intensity Focused Ultrasound for the Treatment of Prostate Cancer. In: Bard, R., Fütterer, J., Sperling, D. (eds) Image Guided Prostate Cancer Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40429-0_22
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DOI: https://doi.org/10.1007/978-3-642-40429-0_22
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