Abstract
Following retinal pigment epithelium (RPE)-choroid graft translocation, visual acuity measurement is only one single modality to test postoperative graft function. Microperimetry, alone or combined with other image modalities, may add valuable information and was therefore used for the follow-up of these patients.
Three examples of microperimetry results in patients with an RPE-choroid graft were evaluated. Microperimetry results were correlated with autofluorescence (AF), fluorescein angiography (FA), and spectral domain optical coherence tomography (SD-OCT) images. Microperimetry indicated that areas with damaged RPE and/or retina, as detected on AF, FA, and SD-OCT, had decreased retinal sensitivity. Furthermore, microperimetry exams were able to give accurate information concerning location and stability of fixation over the graft while documenting a shift in preferred retinal locus over the graft during follow-up.
In conclusion microperimetry may help to interpret anatomical disorders visible on AF, FA, and SD-OCT and the associated effect on visual function, by accurately measuring sensitivity and fixation over specific areas over the graft. In patients with decreased macular function, more intense or longer stimuli might improve the usefulness of the microperimeter. Further studies might explore whether microperimetry data correlate with reading vision, metamorphopsia, or quality of life measurements.
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Acknowledgements
We would like to thank Kristel Maaijwee for collection of the early data.
Funding/Support
1. Royal Visio, Rotterdam, The Netherlands
2. The Rotterdam Eye Hospital Flieringa Research Foundation
3. Combined Ophthalmic Research Rotterdam
4. Stichting Coolsingel
5. MD fonds
Financial Disclosure
Last author J. C. van Meurs is the partial owner of a patent: vibration device for tissue release, with Dutch Ophthalmic Research Center (DORC), Zuidland, the Netherlands, one prototype. The other authors have no financial disclosure.
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van Zeeburg, E.J.T., Cereda, M.G., Spielberg, L.H., van Meurs, J.C. (2014). Retinal Pigment Epithelium and Choroid Graft. In: Midena, E. (eds) Microperimetry and Multimodal Retinal Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40300-2_10
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DOI: https://doi.org/10.1007/978-3-642-40300-2_10
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