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Fluid and Electrolyte Physiology in the Fetus and Neonate

  • Isa F. Ashoor
  • Nilka de Jesús-González
  • Michael J. G. SomersEmail author
Chapter

Abstract

Body fluid distribution and composition in the fetus and neonate differ from what is found in older children and adults. In fact, during intrauterine and perinatal life and persisting into the early postnatal period, high water content characterizes body composition, with significant and dynamic changes then occurring in its distribution as the child ages and grows. Maintaining the appropriate body fluid balance at different developmental stages is critical for cell growth and differentiation and for organ formation and function. Accordingly, a host of unique regulatory mechanisms determine the distribution and composition of body fluids in the fetus and newborn and contribute to ongoing volume and biochemical homeostasis in early childhood. In the following chapter, the main aspects of fluid and electrolyte physiology in the fetus and neonate are reviewed, with particular emphasis on mechanisms regulating water, sodium, potassium, and the divalent ions.

Keywords

Proximal Tubule Atrial Natriuretic Peptide Mineralocorticoid Receptor Total Body Water Distal Tubule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Isa F. Ashoor
    • 1
  • Nilka de Jesús-González
    • 1
  • Michael J. G. Somers
    • 1
    Email author
  1. 1.Division of NephrologyHarvard Medical School, Boston Children’s HospitalBostonUSA

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