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Kidney and Urinary Tract Diseases in the Newborn pp 211–220Cite as

Neonatal Obstructive Uropathy

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Abstract

Obstructive uropathy describes a condition where renal function has been adversely affected by impairment of flow of urine within the collecting system. This condition can be congenital, acquired, reversible, and irreversible. Peters proposed a similar definition for congenital urinary obstruction in children of “a condition of impaired urinary drainage which, if uncorrected, will limit the ultimate functional potential of a developing kidney” [32]. Obstructive uropathy is an important cause of end-stage renal disease in newborns and children [38]. Identification of obstruction and relief of it can minimize its deleterious effect on renal function. This seems obvious, however current clinical criteria, in the form of laboratory or radiographic investigations, to recognize this category of patients is challenging.

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Author information

Authors and Affiliations

  1. Division of Urology, Nationwide Children’s Hospital URO, 555 South 18th Street Suite 6D, Columbus, OH, 43205, USA

    Brian A. VanderBrink MD

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  1. Brian A. VanderBrink MD
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Correspondence to Brian A. VanderBrink MD .

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Editors and Affiliations

  1. Division of Pediatric Nephrology, Hypertension and Renal Transplantation, Kentucky Children’s Hospital, University of Kentucky, Lexington, Kentucky, USA

    Aftab S. Chishti

  2. Urogenital Center, Division of Pediatric Urology, Cincinnati Children’s Medical Center, Cincinnati, Ohio, USA

    Shumyle Alam

  3. Division of Pediatrics, University of Kentucky Children's Hospital, Lexington, Kentucky, USA

    Stefan G. Kiessling

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VanderBrink, B.A. (2014). Neonatal Obstructive Uropathy. In: Chishti, A., Alam, S., Kiessling, S. (eds) Kidney and Urinary Tract Diseases in the Newborn. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39988-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-39988-6_11

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  • Print ISBN: 978-3-642-39987-9

  • Online ISBN: 978-3-642-39988-6

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