Abstract
A gigaseal is a high-resistance seal in order of giga Ohms formed between cell membrane and patching tool. High-resistance seals are needed in order to be able to record high-quality data from cellular ion channels activities. Gigaseal formation has remained a mystery for decades, as no conditions can warrantee a gigaseal. Although the mechanism of gigaseal formation is not yet fully elucidated, studies have been successful in determining the important conditions that should be met for a gigaseal to form.
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Malboubi, M., Jiang, K. (2014). Introduction. In: Gigaseal Formation in Patch Clamping. SpringerBriefs in Applied Sciences and Technology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39128-6_1
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DOI: https://doi.org/10.1007/978-3-642-39128-6_1
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-39127-9
Online ISBN: 978-3-642-39128-6
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