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Carbonylative Coupling Reactions with Organometallic Reagents

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Transition Metal Catalyzed Carbonylation Reactions

Abstract

In carbonylative coupling with organometallic reagent reactions, transmetalation is normally involved in advance of reductive elimination. Diarylketones are their terminal products, which constitute an interesting and versatile structural motif [1] and are frequently present in natural products (e.g., Cotoin, Papaveraldine), in non-steroidal anti-inflammatory drugs (e.g., Suprofen, Ketoprofen), and they occur in UV screens (e.g., Sulisobenzone, Oxybenzone). Based on their importance, various methodologies have been developed for their preparation.

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  1. Leibniz Institute for Catalysis, Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany

    Matthias Beller & Xiao-Feng Wu

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  1. Matthias Beller
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Beller, M., Wu, XF. (2013). Carbonylative Coupling Reactions with Organometallic Reagents. In: Transition Metal Catalyzed Carbonylation Reactions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39016-6_4

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