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Okuläre Oberfläche – infektiös

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Zusammenfassung

ICD-10 Code H01.0 Blepharitis, H10.5 Blepharokonjunktivitis

Die Blepharitis ist eine der häufigsten Augenoberflächenerkrankungen die in der augenärztlichen Praxis vorkommen. Im Verlauf kann es zu Konjunktivitis, Keratitis und Veränderungen des Tränenfilms kommen. Bestehen bereits Augenoberflächenerkrankungen, wie ein Trockenes Auge oder eine allergische Entzündung, werden diese durch eine Blepharitis zusätzlich verstärkt.

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Notes

  1. 1.

    posttraumatischer Kontakt zu verunreinigtem Wasser.

Literatur

Literatur zu Abschn. 3.1

  • AAO (2011) American Academy of Ophthalmology Cornea/External Disease Panel. Prefered Practice Pattern® Guidelines. Blepharitis – Limited Revision. San Francisco, DA: American Academy of Ophthalmology. Available at: www.aao.org/ppp.

    Google Scholar 

  • Amano S (2010) MGD working group: Definition and Diagnostic Criteria for Meibomian Gland Dysfunction. J Eye (AtarashiiGanka) 27:627–631

    Google Scholar 

  • Anonymous (2007) The Definition and Classification of Dry Eye Disease: Report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop. Ocul Surf 5:75–92

    Google Scholar 

  • Auw-Haedrich C, Reinhard T (2007) Chronische Blepharitis: Pathogenese, Klinik und Therapie. Ophthalmologe 104:817–828

    CAS  PubMed  Google Scholar 

  • Benitez-Del-Castillo JM (2012) How to promote and preserve eyelid health. Clin Ophthalmol 6:1689–1698

    PubMed Central  PubMed  Google Scholar 

  • Bowman RW, Dougherty JM, McCulley JP (1987) Chronic blepharitis and dry eyes. Int Ophthalmol Clin 27:27–35

    CAS  PubMed  Google Scholar 

  • Bron AJ, Benjamin L, Snibson GR (1991) Meibomian gland disease: classification and grading of lid changes. Eye 5:395–411

    PubMed  Google Scholar 

  • Butovich IA, Arciniega JC, Wojtowicz JC (2010) Meibomian lipid films and the impact of temperature. Invest Ophthalmol Vis Sci 51:5508–5518

    PubMed  Google Scholar 

  • Dougherty JM, McCulley JP (1986) Bacterial lipases and chronic blepharitis. Invest Ophthalmol Vis Sci 27:486–491

    CAS  PubMed  Google Scholar 

  • Finis D, Schrader S, Geerling G (2012) Meibom-Drüsen Dysfunktion. Klin Monbl Augenheilkd 229:506–513

    CAS  PubMed  Google Scholar 

  • Foulks GN, Bron AJ (2003) Meibomian gland dysfunction: a clinical scheme for description, diagnosis, classification, and grading. Ocul Surf 1:107–126

    PubMed  Google Scholar 

  • Green-Church KB, Butovich I, Willcox M, Borchman D, Paulsen F, Barabino S, Glasgow BJ (2011) The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on Tear film Lipids and Lipid-Protein Interactions in Health and Disease. Invest Ophthalmol Vis Sci 52:1979–1993

    PubMed  Google Scholar 

  • Gutgesell VJ, Stern GA, Hood CI (1982) Histopathology of meibomian gland dysfunction. Am J Ophthalmol 94:383–387

    CAS  PubMed  Google Scholar 

  • Huber-Spitzy V, Böhler-Sommeregger K, Arocker-Mettinger E, Grabner G (1992) Diagnostik, Klinik und Therapie der Blepharitis. Aktuelle Augenheilkd 17:134–139

    Google Scholar 

  • Kaercher T, Brewitt H (2004) Blepharitis. Ophthalmologe 101:1135–1148

    CAS  PubMed  Google Scholar 

  • Keith C (1967) Seborrheic blepharo-kerato-conjunctivitis. Trans Ophthalmol Soc UK 87:85–103

    CAS  PubMed  Google Scholar 

  • Knop E, Knop N, Schirra F (2009) Meibom-Drüsen. Teil II: Physiologie, Charakteristika, Verteilung und Funktion von Meibum. Ophthalmologe 106:884–892

    CAS  PubMed  Google Scholar 

  • Knop E, Knop N, Millar T, Obata H, Sullivan DA (2011) The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on Anatomy, Physiology, and Pathophysiology of the Meibomian Gland. Invest Ophthalmol Vis Sci 52:1938–1978

    PubMed  Google Scholar 

  • Lemp MA, Nichols KK (2009) Blepharitis in the United States 2009: a survey-based perspecive on prevalence and treatment. Ocul Surf 7:1–14

    Google Scholar 

  • Lindsley K, Matsumura S, Hatef E, Akpek EK (2012) Interventions for chronic blepharitis. Cochrane Database Syst Rev 16:5 (CD005556)

    Google Scholar 

  • Liu J, Sheha H, Tseng SC (2010) Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol 10:505–510

    PubMed Central  PubMed  Google Scholar 

  • Mathers WD, Shields WJ, Sachdev MS, Petrol WM, Jester JV (1991) Meibomian gland dysfunction in chronic blepharitis. Cornea 10:277–285

    CAS  PubMed  Google Scholar 

  • McCulley JP (1984) Blepharoconjunctivitis. Int Ophthalmol Clin 24:65–77

    CAS  PubMed  Google Scholar 

  • McCulley JP, Dougherty JM, Deneau DG (1982) Classification of chronic blepharitis. Ophthalmology 89:1173–1180

    CAS  PubMed  Google Scholar 

  • McCulley JP, Dougherty JM (1985) Blepharitis associated with acne rosacea and seborrheic dermatitis. Int Ophthalmol Clin 25:159–172

    CAS  PubMed  Google Scholar 

  • McCulley JP, Shine WE (2000) Changing concepts in the diagnosis and management of blepharitis. Cornea 19:650–658

    CAS  PubMed  Google Scholar 

  • Nelson JD, Shimazaki J, Benitez-del-Castillo JM, Craig JP, McCulley JP, Den S, Foulks GN (2011) The International Workshop on Meibomian Gland Dysfunction: Report of the Definition and Classification Subcommittee. Invest Ophthalmol Vis Sci 52:1930–1937

    PubMed  Google Scholar 

  • Ong BL (1996) Relation between contact lens wear and Meibomian gland dysfunction. Optom Vis Sci 73:208–210

    CAS  PubMed  Google Scholar 

  • Rolando M, Papadia M (2006) Diagnosis and management of the lid and ocular surface disorders. In: Asbell P, Lemp M (Hrsg) Dry Eye Disease: The Clinician’s Guide to Diagnosis and Treatment. Thieme Medical Publishers, New York, S 71

    Google Scholar 

  • Schaumberg DA, Nichols JJ, Papas EB, Tong L, Uchino M, Nichols KK (2011) The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on the Epidemiology of, and Associated Risk Factors for, MGD. Invest Ophthalmol Vis Sci 52:1994–2005

    PubMed  Google Scholar 

  • Tong L, Chaurasia SS, Mehta JS, Beuerman RW (2010) Screening for meibomian gland disease: its relation to dry eye subtypes and symptoms in a tertiary referral clinic in singapore. Invest Ophthalmol Vis Sci 51:3449–3454

    PubMed  Google Scholar 

  • Turnbull AM, Mayfield MP (2012) Blepharitis. BMJ 23:344 (e3328)

    Google Scholar 

  • Ueta M, Iida T, Sakamoto M, Sotozono C, Takahashi J, Kojima K, Okada K, Chen X, Kinoshita S, Honda T (2007) Polyclonality of Staphylococcus epidermidis residing on the healthy ocular surface. J Med Microbiol 56:77–82

    CAS  PubMed  Google Scholar 

  • Wulc AE, Dryden RM, Khatchaturian T (1987) Where is the gray line? Arch Ophthalmol 105:1092–1098

    CAS  PubMed  Google Scholar 

  • Zhao YE, Wu LP, Hu L, Xu JR (2012) Association of blepharitis with Demodex: a meta-analysis. Ophthalmic Epidemiol 19:95–102

    PubMed  Google Scholar 

Literatur zu Abschn. 3.2

  • Cunningham ETJ, Margolis TP (1998) Ocular manifestation of HIV infection. N Engl J Med 339:236–244

    PubMed  Google Scholar 

  • Di Girolamo N (2012) Association of human papilloma virus with pterygia and ocular-surface squamous neoplasia. Eye (Lond) 26:202–11

    Google Scholar 

  • Farooq AV, Shukla D (2012) Herpes simplex epithelial and stromal keratitis: an epidemiologic update. Surv Ophthalmol 57:448–62

    PubMed Central  PubMed  Google Scholar 

  • Kaye S, Choudhary A (2006) Herpes simplex keratitis. Prog Retin Eye Res 25:355–80

    PubMed  Google Scholar 

  • Leveque N, Huguet P, Norder H, Chomel JJ (2010) Enteroviruses responsible for acute hemorrhagic conjunctivitis. Med Mal Infect 40:212–8

    CAS  PubMed  Google Scholar 

  • Liesegang TJ, Skuta GL, Cantor LB (2004) Infectious Disease of the External Eye: Clinical Aspects. External Disease and Cornea. Ophthalmology 7:129–180

    Google Scholar 

  • McDonald EM, de Kock J, Ram FS (2012) Antivirals for management of herpes zoster including ophthalmicus: a systematic review of high-quality randomized controlled trials. Antivir Ther 17:255–64

    CAS  PubMed  Google Scholar 

  • Meyer-Rüsenberg B, Loderstadt U, Richard G, Kaulfers PM, Gesser C (2011) Epidemic keratoconjunctivitis: the current situation and recommendations for prevention and treatment. Dtsch Arztebl Int 108:475–80

    PubMed Central  PubMed  Google Scholar 

  • Ostler HB (1993) Conjunctival Infections and Inflammations. Disease of the External Eye and Adnexa. Mitchell, C. W., Williams & Wilkins, Baltimore, S 67–137

    Google Scholar 

  • Roesel M, Heiligenhaus A, Messmer EM (2010) Clinical presentation of zoster ophthalmicus. Klin Monbl Augenheilkd 227:370–4

    CAS  PubMed  Google Scholar 

  • Rowe AM, St Leger AJ, Jeon S, Dhaliwal DK, Knickelbein JE, Hendricks RL (2013) Herpes keratitis. Prog Retin Eye Res 32:88–101

    CAS  PubMed  Google Scholar 

Literatur zu Abschn. 3.3

  • Balne PK, Nalamada S, Kodiganti M, Taneja M (2012) Fungal keratitis caused by Chaetomium atrobrunneum. Cornea 31(1):94–5

    PubMed  Google Scholar 

  • Belser JA, Davis CT, Balish A, Edwards LE, Zeng H, Maines TR, Gustin KM, Martínez IL, Fasce R, Cox NJ, Katz JM, Tumpey TM (2013) Pathogenesis, Transmissibility, and Ocular Tropism of a Highly Pathogenic Avian Influenza A (H7N3) Virus Associated with Human Conjunctivitis. J Virol 87(10):5746–54

    CAS  PubMed Central  PubMed  Google Scholar 

  • Bialasiewicz AA (2004) Augeninfektionen. In: Adam-Dörr-Link-Lode (Hrsg) Infektiologie. Springer, Heidelberg, S 653–786

    Google Scholar 

  • El-Bahnasawy M, Megahed LA, Saleh AHA, Morsy TA (2013) The rift valley fever: could re-emerge in Egypt again? J Egypt Soc Parasitol 43(1):41–56

    PubMed  Google Scholar 

  • Frühauf J, Massone C, Müllegger RR (2009) Bullous papular-purpuric gloves and socks syndrome in a 42-year-old female: molecular detection of parvovirus B19 DNA in lesional skin. J Am Acad Dermatol 60(4):691–5

    PubMed  Google Scholar 

  • Hayes EB (2009) Zika virus outside Africa. Emerg Infect Dis 15(9):1347–50

    PubMed  Google Scholar 

  • Kim IH, Kwon HJ, Kimabce JH (2013) H9N2 avian influenza virus-induced conjunctivitis model for vaccine efficacy testing. Avian Dis 57(1):83–7

    PubMed  Google Scholar 

  • Kisla TA, Cu-Unjieng A, Sigler L, Sugar J (2000) Medical management of Beauveria bassiana keratitis. Cornea 19(3):405–6

    CAS  PubMed  Google Scholar 

  • Klebe S, Walkow T, Hartmann C, Pleyer U (1999) Immunohistological findings in a patient with unusual late onset manifestations of ligneous conjunctivitis. Br J Ophthalmol 83(7):878–9

    CAS  PubMed  Google Scholar 

  • Kocak Tufan Z, Weidmann M, Bulut C, Kinikli S, Hufert FT, Dobler G, Demiroz AP (2011) Clinical and laboratory findings of a sandfly fever Turkey Virus outbreak in Ankara. J Infect 63(5):375–81

    PubMed  Google Scholar 

  • Lalitha P, Srinivasan M, Rajaraman R, Ravindran M, Mascarenhas J, Priya JL, Sy A, Oldenburg CE, Ray KJ, Zegans ME, McLeod SD, Lietman TM, Acharya NR (2012) Nocardia keratitis: clinical course and effect of corticosteroids. Am J Ophthalmol 154(6):934–939. doi:10.1016/j.ajo.2012.06.001. Epub 2012 Sep 5

    CAS  PubMed Central  PubMed  Google Scholar 

  • Leung EH, Moskalewicz R, Parada JP, Kovach KJ, Bouchard C (2008) Exophiala jeanselmei keratitis after laser in situ keratomileusis. J Cataract Refract Surg 34(10):1809–11. doi:10.1016/j.jcrs. 2008.04.055

    PubMed  Google Scholar 

  • Malecha MA (2004) Fungal keratitis caused by Scopulariopsis brevicaulis treated successfully with natamycin. Cornea 23(2):201–3

    PubMed  Google Scholar 

  • Marshall DH, Brownstein S, Jackson WB, Mintsioulis G, Gilberg SM, Al-Zeerah BF (1997) Post-traumatic corneal mucormycosis caused by Absidia corymbifera. Ophthalmology 104(7):1107–11

    CAS  PubMed  Google Scholar 

  • Mathews MS, Kuriakose T (1995) Keratitis due to Cephaliophora irregularis Thaxter. J Med Vet Mycol 33(5):359–60

    CAS  PubMed  Google Scholar 

  • Mathews MS, Maharajan SV (1999) Exserohilum rostratum causing keratitis in India. Med Mycol 37(2):131–2

    CAS  PubMed  Google Scholar 

  • Maverick KJ, Conners MS (2007) Aureobasidium pullulans fungal keratitis following LASEK. J Refract Surg 23(7):727–9

    PubMed  Google Scholar 

  • Nguyen-Van-Tam JS, Sellwood C (2013) Intervention strategies for emerging respiratory virus infections: policy and public health considerations. Curr Opin Virol 3(2):192–8

    PubMed  Google Scholar 

  • Park KA, Ahn K, Chung ES, Chung TY. Pichia anomala fungal keratitis. Cornea. 2008

    Google Scholar 

  • Reuter G, Boldizsár A, Papp G, Pankovics P (2009) Detection of Aichi virus shedding in a child with enteric and extraintestinal symptoms in Hungary. Arch Virol 154(9):1529–32

    CAS  PubMed  Google Scholar 

  • Ritterband DC, Shah M, Seedor JA (1997) Colletotrichum graminicola: a new corneal pathogen. Cornea 16(3):362–4

    CAS  PubMed  Google Scholar 

  • Schuster V, Seidenspinner S, Zeitler P, Escher C, Pleyer U, Bernauer W, Stiehm ER, Isenberg S, Seregard S, Olsson T, Mingers AM, Schambeck C, Kreth HW (1999) Compound-heterozygous mutations in the plasminogen gene predispose to the development of ligneous conjunctivitis. Blood 93(10):3457–66

    CAS  PubMed  Google Scholar 

  • Thomas PA, Kaliamurthy J (2013) Mycotic keratitis: epidemiology, diagnosis and management. Clin Microbiol Infect 19(3):210–20. doi:10.1111/1469-0691.12126.

    CAS  PubMed  Google Scholar 

  • Thomas BC, Zimmermann S, Völcker HE, Auffarth GU, Dithmar S (2011) Severe Arthrographis kalrae keratomycosis in an immunocompetent patient. Cornea 30(3):364–6. doi:10.1097/ICO.0b013e3181eadeb9

    PubMed  Google Scholar 

  • Wilhelmus KR, Jones DB (2001) Curvularia keratitis. Trans Am Ophthalmol Soc 99:111–30 (discussion 130–2)

    CAS  PubMed Central  PubMed  Google Scholar 

Literatur zu Abschn. 3.4

  • Adhin MR, Grunberg MG, Labadie-Bracho M, Pawiroredjo J (2012) Incidence of Alpha-Herpes virus induced ocular disease in Suriname. J Med Virol 84(12):1937–42

    PubMed  Google Scholar 

  • Adhikary AK, Inada T, Banik U, Mukouyama A, Ikeda Y, Noda M, Ogino T, Suzuki E, Kaburaki T, Numaga J, Okabe N (2004) Serological and genetic characterization of a unique strain of adenovirus involved in an outbreak of epidemic keratoconjunctivitis. J Clin Pathol 57:411–416

    Google Scholar 

  • Abel R, Abel AD (1998) Use of PVP iodine in the treatment of presumptive adenoviral conjunctivitis. nn Ophthalmol Glaucom 30:341–343

    Google Scholar 

  • Ankers Klapper HEPE, Cleator GM, Bailey AS, Tulo AB (1993) The role of a rapid diagnostic test (adenovirus immune dot-blot) in the control of an outbreak of adenovirus type 8 keratoconjunctivitis. Eye 7:15–17

    Google Scholar 

  • Aoki A, Isobe K, Ohno S (1994) Nationwide surveillance program of epidemic conjunctivitis in Japan. In: Bialasiewicz AA, Schaal KP (Hrsg) Infectious disesases of the eye. Butterworth-Heinemann, Philadelphia, S 309–316

    Google Scholar 

  • Bales S, Baumann HG, Schnitzler N (2003) Infektionsschutzgesetz: Kommentar und Vorschriftensammlung, 2. Aufl. Kohlhammer Verlag, Stuttgart, Berlin

    Google Scholar 

  • Bialasiewicz AA, Jahn GJ (1994) Augenbefunde bei Virusinfektionen. Dtsch Ärzteblatt 91B:685–694

    Google Scholar 

  • Bialasiewicz AA (1995) Infektionskrankheiten des Auges. G Fischer Verlag, Stuttgart

    Google Scholar 

  • Bialasiewicz AA, Schaudig U, Draeger J, Richard G, Knöbel H (1996) Descemetocele after PTK in herpetic keratitis without acyclovir prophylaxis. Klin Mbl Augenheilkd 208:120–123

    CAS  Google Scholar 

  • Bialasiewicz AARG (1997) Nosokomiale Infektionen am Auge und krankenhaushygienische Massnahmen in der Augenheilkunde. In: Beck EG, Eikmann T, Tilkes F (Hrsg) Hygiene in Krankenhaus und Praxis, Bd. Bd. 8, III/3.19. Ecomed Verlag, Landshut, S 1–16

    Google Scholar 

  • Bialasiewicz AA (2000) Nosocomial keratitis. Hyg Med 11:458–463

    Google Scholar 

  • Bialasiewicz AA, Brehler R, Draeger J, Schmitz H (2008) Mathematical modelling under specific regards of adenovirus keratoconjunctivitis. Eur J Med Res 13:355–365

    CAS  PubMed  Google Scholar 

  • Chaberny IE, Schnitzler P, Geiss HK, Wendt C (2003) An outbreak of epidemic keratoconjunctivtis in a pediatric unit due to adenovirus type. Infect Control Hosp Epidemiol 8(24):514–519

    Google Scholar 

  • Chang CH, Lin KH, Sheu MM, Huang WL, Wang HZ, Chen CW (2003) The change of etiological agents and clinical signs of epidemic viral conjunctivitis over an 18-year period in southern Taiwan. Graefes Arch Clin Exp Ophthalmol 241:554–60

    PubMed  Google Scholar 

  • Draeger J, Hinzpeter T, Mai K (1969) Tonometer sterilization. Doc Ophthalmol 26:648–663

    CAS  PubMed  Google Scholar 

  • Draeger J, Prueter JW (1990) Importance of diagnosis and preoperative care of the conjunctiva. Klin Mbl Augenheilkd 197:210–213

    CAS  Google Scholar 

  • Dudgeon J (1969) Treatment of adenovirus infection of the eye with 5-iodo2′-deoxyuridine. Br J Ophthalmol 53:530–533

    CAS  PubMed  Google Scholar 

  • Eberwein P, Auw-Hädrich C, Birnbaum F, Maier PC, Reinhard T (2008) Corneal melting after cross-linking and deep lamellar keratoplasty in a keratoconus patient. Klin Monbl Augenheilkd 225(1):96–8

    CAS  PubMed  Google Scholar 

  • Elbadawy HM, Gailledrat M, Desseaux C, Ponzin D, Ferrari S (2012) Targeting herpetic keratitis by gene therapy. J Ophthalmol 2012:594–869

    Google Scholar 

  • Ford E, Nelson KE, Warren D (1987) Epidemiology of epidemic keratoconjunctivitis. Epidemiol Rev 9:244–261

    CAS  PubMed  Google Scholar 

  • Freyler H, Sehorst W (1976) The fate of corneal infiltrations in cases of epidemic keratoconjunctvitis. Wien Klin Wochenshcr 28(88):341–343

    Google Scholar 

  • Fujimoto T, Okafuji T, Okafuji T, Ito M, Nukuzuma S, Chikahira M, Nishio O (2004) Evaluation of a bedside immunochromatographic test for detection of adenovirus in respiratory samples, by comparison to virus isolation and real-time PCR. J Clin Microbiol 42:5489–5492

    CAS  PubMed Central  PubMed  Google Scholar 

  • Gordon YJ, Gordon RY, Romanowski E, Araullo-Cruz TP (1993) Prolonged recovery of desiccated adenoviral serotypes 5, 8, 19 from plastic and metal surfaces in vitro. Ophthalmology 100:1835–1839

    CAS  PubMed  Google Scholar 

  • Gordon YJ, Romanowski EG, Araullo-Cruz T (1994) Topical HPMPC inhibits adenovirus type 5 in the New Zealand rabbit ocular replication model. Invest Ophthalmol Vis Sci 35:4135–4143

    CAS  PubMed  Google Scholar 

  • Gottsch JD, Froggatt JW 3rd, Smith DM, Dwyer DM, Borenstein P, Karanfil LV, Vitale S, Goldberg MF (1999) Prevention and control of epidemic keratoconjunctivitis in a teaching eye institute. Ophthalmic Epidemiol 6:29–39

    CAS  PubMed  Google Scholar 

  • Herpetic Eye Disease Study Group (2000) Oral acyclovir for herpes simplex virus eye disease: effect on prevention of epithelial keratitis and stromal keratitis. Herpetic Eye Disease Study Grou. Arch Ophthalmol 118(8):1030–1036

    Google Scholar 

  • Hillenkamp J, Reinhard T, Ross RS, Bohringer D, Cartsburg O, Roggendorf M, DeClerq E, Godehardt E, Sundmacher R (2001) Topical treatment of adenoviral keratoconjunctivitis with 0.2 % cidofovir and 1 % cyclosporine: a controlled clinical pilot study. Arch Ophthalmol 119:1487–1491

    CAS  PubMed  Google Scholar 

  • Himaki T, Masui Y, Chono K, Daikoku T, Takemoto M, Haixia B, Okuda T, Suzuki H, Shiraki K (2012) Efficacy of ASP2151, a helicase-primase inhibitor, against thymidine kinase-deficient herpes simplex virus type 2 infection in vitro and in vivo. Antiviral Res 93(2):301–304

    CAS  PubMed  Google Scholar 

  • Kemp MC, Hierholzer JC, Cabradilla CP, Obijeski JF (1983) The changing etiology of epidemic keratoconjunctivitis: antigenic and restriction enzyme analyses of adenovirus types 19 and 37 isolated over a 10 year period. J Infect Dis 148:24–33

    CAS  PubMed  Google Scholar 

  • Klauss V, Schaller UC, Bialasiewicz AA (2002) Importance and epidemiology of infectious eye diseases. In: Kramer A, Behrens-Baumann W (eds.): Antiseptic prophylaxis and therapy in ocular infections. Dev Ophthalmol 33:145–190

    Google Scholar 

  • Knappe S, Stave J, Guthoff RF (2004) Epidemic keratoconjunctivitis – in vivo representation of corneal histopathological structures with confocal Rostocker laser scanning microscope (RLSM) Ophthalmologe

    Google Scholar 

  • Krumpaszky HG, Klauss V (1996) Epidemiology of blindness and eye diseases. Ophthalmologica 210:1–84

    CAS  PubMed  Google Scholar 

  • Labetoulle M, Auquier P, Conrad H et al (2005) Incidence of herpes simplex virus keratitis in France. Ophthalmology 112:888–95

    CAS  PubMed  Google Scholar 

  • Liesegang TJ, Melton LJ, Daly PJ et al (1989) Epidemiology of ocular herpes simplex. Incidence in Rochester, Minn, 1950 through 1982. Arch Ophthalmol 107:1155–9

    CAS  PubMed  Google Scholar 

  • Loutsch JM, Sainz B Jr, Marquart ME, Zheng X, Kesavan P, Higaki S, Hill JM, Tal-Singer R (2001) Effect of famciclovir on herpes simplex virus type 1 corneal disease and establishment of latency in rabbits. Antimicrob Agents Chemother 45(7):2044–2053

    CAS  PubMed Central  PubMed  Google Scholar 

  • McDonald EM, de Kock J, Ram FS (2012) Antivirals for management of herpes zoster including ophthalmicus: a systematic review of high-quality randomized controlled trials. Antivir Ther 17(2):255–264

    CAS  PubMed  Google Scholar 

  • Van L Modi S, Gewirtzman A, Mendoza N, Bartlett B, Tremaine AM, Tyring S (2008) Single-day treatment for orolabial and genital herpes: a brief review of pathogenesis and pharmacology. Ther Clin Risk Manag 4(2):409–417

    CAS  PubMed Central  PubMed  Google Scholar 

  • Montessori V, Scharf S, Holland S, Werker DH, Roberts FJ, Bryce E (1998) Epidemic keratoconjunctivitis outbreak at a tertiary referral eye care clinic. Am J Infect Control 26:399–405

    CAS  PubMed  Google Scholar 

  • Mortensen KK, Sjolie AK (1979) Keratitis dendritica. An epidemiological investigation. Acta Ophthalmologica 57:750–754

    CAS  PubMed  Google Scholar 

  • Mueller AJ, Klauss V (1993) Main sources of infection in 145 cases of epidemic keratoconjunctivitis. Ger J Ophthalmol 2:224–227

    CAS  PubMed  Google Scholar 

  • Nagel M, Teuchner B, Pottinger E, Ulmer H, Gottardi W (2000) Tolerance of N-chlorotaurine, a new antimicrobial agent, in infectious conjunctivitis – a phase II pilot study. Ophthalmologica 214:111–4

    Google Scholar 

  • Quentin CD, Tondrow M, Vogel M (1999) Phototherapeutische Keratektomie nach Keratokonjunktivitis Epidemica. Ophthalmologe 96:92–96

    CAS  PubMed  Google Scholar 

  • Pavan-Langston D, Rong BL, Dunkel EC (1989) Extraneuronel herpetic latency: Animal and human corneal studies. Acta Ophthalmol 67:135–141

    Google Scholar 

  • Ribaric V (1976) The incidence of herpetic keratitis among populations. Ophthalmologica 173:19–22

    CAS  PubMed  Google Scholar 

  • RKI-Ratgeber Infektionskrankheiten – Merkblätter für Ärzte (2004) Keratoconjunctivitis epidemica und andere Konjunktivitiden durch Adenoviren

    Google Scholar 

  • Romanowski EG, Zates KA, Gordon YJ (2002) Topical corticosteroids of limited potency promote adenovirus replication in the Ad5/NZW rabbit ocular model. Cornea 21:289–291

    PubMed  Google Scholar 

  • Sambursky R, Trattler W, Tauber S, Starr C, Friedberg M, Boland T, McDonald M, DellaVecchia M, Luchs J (2012) Sensitivity and specificity of the AdenoPlus test for diagnosing adenoviral conjunctivitis. JAMA Ophthalmol 131:17–22

    Google Scholar 

  • Schmitz H, Draeger J, Emmerich P (1990) Tonometer sterilization. The inactivation of HSV 1 and Ad 2 by ultraviolet irradiation. Klin Mbl Augenheilkd 196:225–227

    CAS  Google Scholar 

  • Schuhmacher A, Reichling J, Schnitzler P (2003) Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro. Phytomedicine 10(6–7):504–510

    CAS  PubMed  Google Scholar 

  • Sundmacher R, Wigand R, Cantell K (1982) The value of exogenous interferon in adenovirus keratoconjunctivitis. Graefes Arch Clin Exp Ophthalmol 218:139–145

    CAS  PubMed  Google Scholar 

  • Takeuchi S, Itoh N, Uchio E, Tanaka K, Kitamura N, Kanai H, Isobe K, Aoki K, Ohno S (1999) Adenovirus strains of subgenus D associated with nosocomial infection as nuew etiological agents of epidemic keratoconjunctivitis. J Clin Microbiol 37:3392–3394

    CAS  PubMed Central  PubMed  Google Scholar 

  • Ward JB, Siojo LG, Waller SG (1993) A prospective masked clinical trial of trifluridien, dexamethasone and artificial tears in the treatment of epidemic keratoconjunctivitis. Cornea 12:216–221

    CAS  PubMed  Google Scholar 

  • Wegman DH, Guinee VE, Millian SJ (1970) Epidemic keratoconjunctivitis. Am J Pub Health 60:1230–1237

    CAS  PubMed  Google Scholar 

  • Wu E, Trauger SA, Pache L, Mullen TM, von Seggern DJ, Siuzdak G, Nemerow GR (2004) Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis. J Virol 78:3897–38905

    CAS  PubMed Central  PubMed  Google Scholar 

  • Yabiku ST, Yabiku MM, Bottós KM, Araújo AL, Freitas D, Belfort R Jr (2011) Ganciclovir 0.15 % ophthalmic gel in the treatment of adenovirus keratoconjunctivitis. Arq Bras Oftalmol 74:417–21

    PubMed  Google Scholar 

  • Young RC, Hodge DO, Liesegang TJ, Baratz KH (2010) The Incidence, Recurrence and Outcomes of Herpes Simplex Virus Eye Disease in Olmsted County, Minnesota, 1976 through 2007: The Impact of Oral Antiviral Prophylaxis. Arch Ophthalmol 128(9):1178–1183

    PubMed Central  PubMed  Google Scholar 

Literatur zu Abschn. 3.5

  • Dart JK, Saw VP, Kilvington S (2009) Acanthamoeba keratitis: diagnosis and treatment update 2009. Am J Ophthalmol 148(4):487–499

    PubMed  Google Scholar 

  • Clarke DW, Niederkorn JY (2006) The immunobiology of Acanthamoeba keratitis. Microbes Infect 8(5):1400–5

    CAS  PubMed  Google Scholar 

  • Clarke DW, Niederkorn JY (2006) The pathophysiology of Acanthamoeba keratitis. Trends Parasitol 22(4):175–80

    CAS  PubMed  Google Scholar 

  • Hiti K, Walochnik J, Haller-Schober EM, Faschinger C, Aspöck H (2006) A new Multipurpose Contact Lens Disinfection System in Comparison with eight other Solutions – Effectiveness against Acanthamoeba. Cornea 25(4):423–7

    PubMed  Google Scholar 

  • Khan NA (2009) Acanthamoeba – Biology and Pathogenesis. Caister Academic Press, Norfolk, Great Britain, S 290

    Google Scholar 

  • Page FC, Siemensma FJ (1991) Nackte Rhizopoda und Heliozoea. In: Matthes D (Hrsg) Protozoenfauna, Bd. 2. G. Fischer, Stuttgart

    Google Scholar 

  • Polat ZA, Obwaller A, Vural A, Walochnik J (2012) Efficacy of miltefosine for topical treatment of Acanthamoeba keratitis in Syrian hamsters. Parasitol Res 110(2):515–20

    PubMed  Google Scholar 

  • Schuster FL (2002) Cultivation of pathogenic and opportunistic free-living amebas. Clin Microbiol Rev 15(3):342–54

    PubMed Central  PubMed  Google Scholar 

  • Visvesvara GS (2010) Amebic meningoencephalitides and keratitis: challenges in diagnosis and treatment. Curr Opin Infect Dis 23(6):590–4

    CAS  PubMed  Google Scholar 

  • Visvesvara GS, Moura H, Schuster FL (2007) Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol Med Microbiol 50(1):1–26

    CAS  PubMed  Google Scholar 

  • Walochnik J, Aspöck H (2005) Die Diagnostik von Infektionen mit freilebenden Amöben (FLA). J Lab Med 29(6):446–456

    CAS  Google Scholar 

  • Walochnik J, Duchêne M, Eibl H, Aspöck H (2003) Die Behandlung der Acanthamoeba-Keratitis: Möglichkeiten, Probleme und neue Wege. Wien Klin Wochenschr 115(3):10–7

    PubMed  Google Scholar 

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Aspöck, H. et al. (2014). Okuläre Oberfläche – infektiös. In: Pleyer, U. (eds) Entzündliche Augenerkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38419-6_3

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