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Entzündliche Augenerkrankungen

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Zusammenfassung

Gemäß Klassifikation der „Standardization of Uveitis Nomenclature“ (SUN) Working Group handelt es sich bei der intermediären Uveitis um eine intraokulare Entzündung mit dem Glaskörper als primärem Entzündungsort. Als Pars planitis wird eine Untergruppe der intermediären Uveitis bezeichnet, bei der sich „Snowballs“ und „Snowbanks“ finden, jedoch keine zugrundeliegende Infektion oder Systemerkrankung nachweisbar , d. h. das Krankheitsbild „idiopathisch“ ist. Lässt sich hingegen eine Infektion oder Systemerkrankung (z. B. Multiple Sklerose) als Ursache nachweisen, soll der Begriff intermediäre Uveitis verwendet werden.

Ungefähr 20 % aller Uveitis-Patienten leiden an einer intermediären Uveitis. Bezogen auf die Lokalisation der Entzündung im Auge ist sie die zweithäufigste Uveitisform, sowohl im Erwachsenen- als auch im Kindesalter. Die Inzidenz der intermediären Uveitis wird mit 1,5/100.000, die Prävalenz mit 4,0/100.000 angegeben. Die intermediäre Uveitis betrifft überwiegend Patienten vom Kindesalter bis zum vierten Lebensjahrzehnt, wobei jedoch auch ältere Personen erkranken können. Eine Geschlechtspräferenz wird nicht beobachtet. In 70–90 % der Fälle sind beide Augen erkrankt, wobei häufig eine Asymmetrie im Schweregrad zwischen beiden Augen beobachtet wird.

Man geht davon aus, dass es sich bei der intermediären Uveitis um eine T-Zell-vermittelte Erkrankung handelt. Es wird hier auf ▶ Abschn. 5.1.2 zur Immunologie intraokularer Entzündungen verwiesen.

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Authors and Affiliations

  1. Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Berlin Charité Campus Virchow-Klinikum, Berlin, Deutschland

    Uwe Pleyer Prof. Dr.

  2. 6th Floor Duncan Building, University of Liverpool, Daulby Street, Liverpool, L69 3GA, Großbritannien

    S. E. Coupland Prof.

  3. Augenklinik, Universitätsklinikum Tübingen, Schleichstr. 12-16, 72076, Tübingen, Deutschland

    Christoph Deuter Dr. med.

  4. Klinik für Augenheilkunde, Charité-Universitätsmedizin Berlin CVK, Augustenburger Platz 1, 13353, Berlin, Deutschland

    Enken Gundlach Dr. med.

  5. Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Deutschland

    Horst Helbig Prof. Dr. med., Agnes B. Renner PD Dr. med. & Teresa Barth Dr. med.

  6. Avenue Bergières 2, 1004, Lausanne, Schweiz

    Carl Herbort PD Dr. med.

  7. Campus Virchow Klinikum, Klinik für Augenheilkunde, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland

    Florian Heußen Dr. med. & Sibylle Winterhalter Dr. med.

  8. Augenzentrum Wolfsburg, Am Spieker 10, 38442, Wolfsburg, Deutschland

    Tobias Hudde PD Dr.

  9. Institut für Gewebediagnostik, HELIOS Klinikum Emil von Behring Berlin, Walterhöferstr. 11, 14165, Berlin, Deutschland

    Doris Jähne Dr.

  10. Department of Ophthalmology, University Hospital Zürich, Rämistr. 100, 8091, Zürich, Schweiz

    Pascal B. Knecht MD, FEBO

  11. Universitätsaugenklinik Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland

    Thomas Neß PD Dr. med.

  12. Klinik für Ophthalmologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Hegewischstr. 2, 24105, Kiel, Deutschland

    Bernhard Nölle Dr. med.

  13. Centre for Ophthalmic Specialised Care (COS), Clinique Montchoisi, Rue de la Grotte 6, 1003, Lausanne, Schweiz

    Marina Papadia MD, PhD

  14. Augenchirurgische Tagesklinik Ambimed, Klingentalstrasse 9, 4057, Basel, Schweiz

    Torsten Schlote Prof. Dr. med.

  15. Klinik für Augenheilkunde, Charité-Universitätsmedizin Berlin CBF, Hindenburgdamm 30, 12203, Berlin, Deutschland

    Nicole Stübiger Prof. Dr. med.

  16. Augenklinik, Klinikum der Universität München, Mathildenstr. 8, 80336, München, Deutschland

    Stephan Thurau Prof. Dr. med.

  17. Augenklinik, Universitätsklinikum Tübingen, Schleichstr. 12-16, 72076, Tübingen, Deutschland

    Manfred Zierhut Prof. Dr. med.

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  1. S. E. Coupland Prof.
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Editors and Affiliations

  1. Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Berlin Charité Campus Virchow-Klinikum, Berlin, Berlin, Germany

    Uwe Pleyer

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Coupland, S.E. et al. (2014). Nichtinfektiös. In: Pleyer, U. (eds) Entzündliche Augenerkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38419-6_10

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