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Conjunctival and Corneal Tumors: Melanoma

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Clinical Ophthalmic Oncology

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Abstract

Conjunctival nevi, conjunctival primary acquired melanosis (PAM), and conjunctival melanomas all arise from melanocytes that migrate from the neural crest to reside in the conjunctival epithelium. Conjunctival melanoma may arise de novo or from preexisting conjunctival nevus or PAM. In the medical literature, conjunctival melanoma is sometimes labeled together with uveal melanoma as “ocular melanoma.” The clinical behavior, molecular biology, and the histopathologic features of conjunctival and uveal melanoma are clearly different; therefore, conjunctival melanoma should be approached as an entity separate from uveal melanoma.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    Jacob Pe’er MD

  2. Oakland University William Beaumont School of Medicine, Rochester, MI, USA

    Robert Folberg MD

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  1. Jacob Pe’er MD
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  2. Robert Folberg MD
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Correspondence to Jacob Pe’er MD .

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Editors and Affiliations

  1. Department of Ophthalmology, Hadassah-Hebrew University, Jerusalem, Israel

    Jacob Pe'er

  2. Dept. of Ophthalmic Oncology, Cole Eye Institute Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Arun D. Singh

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Pe’er, J., Folberg, R. (2014). Conjunctival and Corneal Tumors: Melanoma. In: Pe'er, J., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38336-6_18

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  • DOI: https://doi.org/10.1007/978-3-642-38336-6_18

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