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Clinical Ophthalmic Oncology pp 149–160Cite as

Conjunctival and Corneal Tumors: Benign Epidermal and Melanocytic Tumors

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Abstract

Benign tumors of the conjunctiva are much more common than malignant tumors of the conjunctiva. In this chapter, benign tumors of epithelial and melanocytic origin, which comprise the majority of the conjunctival tumors, are described. Benign conjunctival tumors of stromal origin are described in Chap. 18.

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References

  1. Spencer WH. Chapter 2, Conjunctiva. In: Spencer WH, editor. Ophthalmic pathology, an atlas and textbook. 4th ed. Philadelphia: Saunders; 1996. p. 106–25.

    Google Scholar 

  2. Campbell RJ, Sobin LH. Tumors of the conjunctiva and caruncle. In: Histological typing of tumours of the eye and its adnexa, World Health Organization histological classification of tumours. 2nd ed. Berlin: Springer; 1998. p. 9–15.

    Chapter  Google Scholar 

  3. Shields CL, Shields JA. Tumors of the conjunctiva and cornea. Surv Ophthalmol. 2004;49:3–24.

    Article  PubMed  Google Scholar 

  4. Sjo N, Heegaard S, Prause JU. Conjunctival papilloma. A histopathologically based retrospective study. Acta Ophthalmol Scand. 2000;78:663–6.

    Article  PubMed  CAS  Google Scholar 

  5. Lass JH, Jenson AB, Papale JJ, et al. Papillomavirus in human conjunctival papillomas. Am J Ophthalmol. 1983;95:364–8.

    PubMed  CAS  Google Scholar 

  6. Sjo NC, von Buchwald D, Cassonnet P, et al. Human papillomavirus in normal conjunctival tissue and in conjunctival papilloma: types and frequencies in a large series. Br J Ophthalmol. 2007;91:1014–5.

    Article  PubMed  Google Scholar 

  7. Schechter BA, Rand WJ, Velazquez GE, et al. Treatment of conjunctival papillomata with topical interferon Alfa-2b. Am J Ophthalmol. 2002;134:268–70.

    Article  PubMed  CAS  Google Scholar 

  8. Lass JH, Foster CS, Grove AS, et al. Interferon-alpha therapy of recurrent conjunctival papillomas. Am J Ophthalmol. 1987;103:294–301.

    PubMed  CAS  Google Scholar 

  9. Hawkins AS, Yu J, Hamming NA, et al. Treatment of recurrent conjunctival papillomatosis with mitomycin C. Am J Ophthalmol. 1999;128:638–40.

    Article  PubMed  CAS  Google Scholar 

  10. Bosniak SL, Novick NL, Sachs ME. Treatment of recurrent squamous papillomata of the conjunctiva by carbon dioxide laser vaporization. Ophthalmology. 1986;93:1078–82.

    PubMed  CAS  Google Scholar 

  11. Shields CL, Lally MR, Singh AD, et al. Oral cimetidine (Tagamet) for recalcitrant, diffuse conjunctival papillomatosis. Am J Ophthalmol. 1999;128:362–4.

    Article  PubMed  CAS  Google Scholar 

  12. Streeten BW, Carrillo R, Jamison R, et al. Inverted papilloma of the conjunctiva. Am J Ophthalmol. 1979;88:1062–6.

    PubMed  CAS  Google Scholar 

  13. Jakobiec FA, Harrison W, Aronian D. Inverted mucoepidermoid papillomas of the epibulbar conjunctiva. Ophthalmology. 1987;94:283–7.

    PubMed  CAS  Google Scholar 

  14. Tseng SH, Chen YT, Huang FC, et al. Seborrheic keratosis of conjunctiva simulating a malignant melanoma: an immunocytochemical study with impression cytology. Ophthalmology. 1999;106:1516–20.

    Article  PubMed  CAS  Google Scholar 

  15. Munro S, Brownstein S, Liddy B. Conjunctival keratoacanthoma. Am J Ophthalmol. 1993;116:654–5.

    PubMed  CAS  Google Scholar 

  16. Allingham RR, Seo B, Rampersaud E, et al. A duplication in chromosome 4q35 is associated with hereditary benign intraepithelial dyskeratosis. Am J Hum Genet. 2001;68:491–4.

    Article  PubMed  CAS  Google Scholar 

  17. Jakobiec FA, Perry HD, Harrison W, et al. Dacryoadenoma. A unique tumor of the conjunctival epithelium. Ophthalmology. 1989;96:1014–20.

    PubMed  CAS  Google Scholar 

  18. Say EA, Shields CL, Bianciotto C, et al. Oncocytic lesions (oncocytoma) of the ocular adnexa: report of 15 cases and review of literature. Ophthal Plast Reconstr Surg. 2012;28:14–21.

    Article  PubMed  Google Scholar 

  19. Mauriello Jr JA, Napolitano J, McLean I. Actinic keratosis and dysplasia of the conjunctiva: a clinicopathological study of 45 cases. Can J Ophthalmol. 1995;30:312–6.

    PubMed  Google Scholar 

  20. Folberg R. Chapter 2, Melanocytic lesions of the conjunctiva. In: Spencer WH, editor. Ophthalmic pathology, an atlas and textbook. 4th ed. Philadelphia: Saunders; 1996. p. 125–55.

    Google Scholar 

  21. Shields CL, Fasiudden AF, Mashayekhi A, et al. Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol. 2004;122:167–75.

    Article  PubMed  Google Scholar 

  22. Kantelip B, Boccard R, Nores JM, et al. A case of conjunctival Spitz nevus: review of literature and comparison with cutaneous locations. Ann Ophthalmol. 1989;21:176–9.

    PubMed  CAS  Google Scholar 

  23. Blicker JA, Rootman J, White VA. Cellular blue nevus of the conjunctiva. Ophthalmology. 1992;99:1714–7.

    PubMed  CAS  Google Scholar 

  24. Demirci H, Shields CL, Shields JA, et al. Malignant melanoma arising from unusual conjunctival blue nevus. Arch Ophthalmol. 2000;118:1581–4.

    Article  PubMed  CAS  Google Scholar 

  25. Zamir E, Mechoulam H, Micera A, et al. Inflamed juvenile conjunctival naevus: clinicopathological characterisation. Br J Ophthalmol. 2002;86:28–30.

    Article  PubMed  Google Scholar 

  26. Levi-Schaffer F, Micera A, Zamir E, et al. Nerve growth factor and eosinophils in inflamed juvenile conjunctival nevus. Invest Ophthalmol Vis Sci. 2002;43:1850–6.

    PubMed  Google Scholar 

  27. Singh AD, De Potter P, Fijal BA, et al. Lifetime prevalence of uveal melanoma in white patients with ocula (dermal) melanocytosis. Ophthalmology. 1998;105:195–8.

    Article  PubMed  CAS  Google Scholar 

  28. Santos A, Gomez-Leal A. Lesions of the lacrimal caruncle. Clinicopathologic features. Ophthalmology. 1994;101:943–9.

    PubMed  CAS  Google Scholar 

  29. Ostergaard J, Prause JU, Heegaard S. Caruncular lesions in Denmark 1978–2002: a histopathological study with correlation to clinical referral diagnosis. Acta Ophthalmol Scand. 2006;84:130–6.

    Article  PubMed  Google Scholar 

  30. Kaeser PF, Uffer S, Zografos L, et al. Tumors of the caruncle: a clinicopathologic correlation. Am J Ophthalmol. 2006;142:448–55.

    Article  PubMed  Google Scholar 

  31. Aponte EP, Schoenfield L, Stern RM, Singh AD. A ductal cyst of lacrimal origin. Adv Ocul Care. 2010:29–30.

    Google Scholar 

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Authors and Affiliations

  1. Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    Jacob Pe’er MD

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  1. Jacob Pe’er MD
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Correspondence to Jacob Pe’er MD .

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Editors and Affiliations

  1. Department of Ophthalmology, Hadassah-Hebrew University, Jerusalem, Israel

    Jacob Pe'er

  2. Dept. of Ophthalmic Oncology, Cole Eye Institute Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Arun D. Singh

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© 2014 Springer-Verlag Berlin Heidelberg

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Pe’er, J. (2014). Conjunctival and Corneal Tumors: Benign Epidermal and Melanocytic Tumors. In: Pe'er, J., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38336-6_15

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  • DOI: https://doi.org/10.1007/978-3-642-38336-6_15

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-38335-9

  • Online ISBN: 978-3-642-38336-6

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