Abstract
This work addresses the generation of a personalized treatment plan from multiple clinical guidelines, for a patient with multiple diseases (comorbid patient), as a multi-agent cooperative planning process that provides support to collaborative medical decision-making. The proposal is based on a multi-agent planning architecture in which each agent is capable of (1) planning a personalized treatment from a temporal Hierarchical Task Network (HTN) representation of a single-disease guideline, and (2) coordinating with other planning agents by both sharing disease specific knowledge, and resolving the eventual conflicts that may arise when conciliating different guidelines by merging single-disease treatment plans. The architecture follows a life cycle that starting from a common specification of the main high-level steps of a treatment for a given comorbid patient, results in a detailed treatment plan without harmful interactions among the single-disease personalized treatments.
Work partially supported by projects P08-TIC-3572 and TIN2011-27652-C03-03/01.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
GLINDA: GuideLine INteraction Detection Architecture, http://glinda-project.stanford.edu/
Abidi, S.R.: A conceptual framework for ontology based automating and merging of clinical pathways of comorbidities. In: Riaño, D. (ed.) K4HelP 2008. LNCS, vol. 5626, pp. 55–66. Springer, Heidelberg (2009)
Boyd, C.M., Darer, J., Boult, C., Fried, L.P., Boult, L., Wu, A.W.: Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: Implications for pay for performance. JAMA 294(10), 716–724 (2005)
Fdez-Olivares, J., Castillo, L., Cózar, J., García Pérez, O.: Supporting clinical processes and decisions by hierarchical planning and scheduling. Comput. Intell. 27(1), 103–122 (2011)
González-Ferrer, A., ten Teije, A., Fdez-Olivares, J., Milian, K.: Automated generation of patient-tailored electronic care pathways by translating computer-interpretable guidelines into hierarchical task networks. Artif. Intell. Med. (2012) (in Press)
Hing, M.M., Michalowski, M., Wilk, S., Michalowski, W., Farion, K.: Identifying inconsistencies in multiple clinical practice guidelines for a patient with co-morbidity. In: IEEE International Conference on BIBM Wkshp., pp. 447–452 (2010)
Lozano, E., Marcos, M., Martínez-Salvador, B., Alonso, A., Alonso, J.R.: Experiences in the development of electronic care plans for the management of comorbidities. In: Riaño, D., ten Teije, A., Miksch, S., Peleg, M. (eds.) KR4HC 2009. LNCS, vol. 5943, pp. 113–123. Springer, Heidelberg (2010)
Lugtenberg, M., Burgers, J.S., Clancy, C., Westert, G.P., Schneider, E.C.: Current guidelines have limited applicability to patients with comorbid conditions: A systematic analysis of evidence-based guidelines. PLoS ONE 6(10), e25987 (2011)
de Weerdt, M., Clement, B.: Introduction to planning in multiagent systems. Multiagent and Grid Systems 5(4), 345–355 (2009)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Sánchez-Garzón, I., Fdez-Olivares, J., Onaindía, E., Milla, G., Jordán, J., Castejón, P. (2013). A Multi-agent Planning Approach for the Generation of Personalized Treatment Plans of Comorbid Patients. In: Peek, N., Marín Morales, R., Peleg, M. (eds) Artificial Intelligence in Medicine. AIME 2013. Lecture Notes in Computer Science(), vol 7885. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38326-7_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-38326-7_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-38325-0
Online ISBN: 978-3-642-38326-7
eBook Packages: Computer ScienceComputer Science (R0)