Abstract
A new water-soluble heme iron (WSHI) was prepared and characterized. Crystalline hemin and L-arginate in molar proportions of 1:3 were mixed in a acetone solution (acetone: water = 100:10, V: V), stirred at 25 °C, for 12 h, and then centrifuged, washed with acetone, freeze-dried, referred to as WSHI. No clear differences in UV spectrum, IR spectrum between hemin-arginate and hemin was founded, while a notable distinct of thermal sensitivity occurred by differential thermal analysis (DTA), which partly explained dissolution elevation of hemin-arginate. Hemin-arginate is stable and no coagulate occurred in Carbonate solution, phosphate solution, or tea water, respectively. So, Hemin-arginate can be used as a new heme iron supplement in food additives, functional foods, and pharmaceuticals.
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Acknowledgments
The present work was supported by grants from the Special Fund for Agroscientific Research in the Public Interest (No. 201303082-3), National Natural Science Foundation of China (No. 31000755), and Key Project of Chinese Ministry of Education (No. 211008).
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Wang, W., Liu, T., Zhang, Y., Chen, R., Liu, A. (2014). In situ Preparation and Characteristics of a New Water-Soluble Heme Iron Via Hemin-Arginate Coacervation. In: Zhang, TC., Ouyang, P., Kaplan, S., Skarnes, B. (eds) Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012). Lecture Notes in Electrical Engineering, vol 251. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37925-3_152
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