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Funktionelle Bildgebung bei Schmerz

  • Chapter
Praktische Schmerzmedizin

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Zusammenfassung

Der Einsatz funktioneller Bildgebungsverfahren zur Untersuchung experimenteller und klinischer Schmerzzustände hat in der Vergangenheit maßgeblich zum Verständnis neuronaler Prozesse und deren Lokalisation im Gehirn beigetragen. Vor der Entwicklung dieser Verfahren basierte unser Wissen über die Schmerzverarbeitung bzw. die funktionelle Anatomie v. a. auf molekularbiologischen und elektrophysiologischen Befunden (Penfield et al. 1937, Stowell et al. 1984), Tierversuchen und Läsionsstudien (Head et al. 1911, Folz et al. 1962, Berthier et al. 1988). Im Gegensatz dazu stehen heute mit den modernen bildgebenden Verfahren Instrumente zur Verfügung, die nichtinvasive Untersuchungen in vivo und bei vollem Bewusstsein erlauben. Diese Techniken ermöglichen völlig neue Einblicke in die Schmerzverarbeitung, die zeitliche Dynamik sowie die Modulation.

Mit Hilfe funktioneller Bildgebungsmethoden konnten zudem bedeutende Einblicke in die Pathogenese von chronischen Schmerzerkrankungen gewonnen werden, die unser Verständnis über die zugrundeliegenden Mechanismen stark erweitert haben.

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Authors and Affiliations

  1. Neurologische Klinik und Poliklinik der Technischen, Universität München Klinikum rechts der Isar, München, Ismaninger Straße 22, 81675

    Dr. rer. nat. A. Stankewitz & Prof. Dr. med. Dr. rer. nat. T. R. Tölle

  2. Neurologisch-Neurochirurgische Poliklinik und Abteilung für Neuroradiologie, Universitätsspital Basel, Basel, Petersgraben 4, 4031, Schweiz

    Prof. Dr. med. T. Sprenger

  3. Benedictus Krankenhaus Feldafing, Feldafing, Dr.-Appelhans-Weg 6, 82340

    PD Dr. med. M. Valet

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  1. Dr. rer. nat. A. Stankewitz
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  3. PD Dr. med. M. Valet
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  4. Prof. Dr. med. Dr. rer. nat. T. R. Tölle
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Editors and Affiliations

  1. Sektion Neurologische Schmerzforschung und -therapie Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel, Arnold-Heller-Straße 3, Haus 41, 24105

    Ralf Baron

  2. Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Hannover, Carl-Neuberg-Straße 1, 30625

    Wolfgang Koppert

  3. Schmerz-Tagesklinik und -Ambulanz, Universitätsmedizin Göttingen, Göttingen, Robert-Koch-Straße 40, 37075

    Anne Willweber-Strumpf

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Stankewitz, A., Sprenger, T., Valet, M., Tölle, T. (2013). Funktionelle Bildgebung bei Schmerz. In: Baron, R., Koppert, W., Strumpf, M., Willweber-Strumpf, A. (eds) Praktische Schmerzmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37605-4_11

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  • DOI: https://doi.org/10.1007/978-3-642-37605-4_11

  • Publisher Name: Springer, Berlin, Heidelberg

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