Melanoma Arising in a Pre-Existent Nevus

Abstract

Melanoma develops in a preexisting conventional nevus in two major patterns. By far the most frequent form is melanoma arising in the junctional portion of a nevus. This type of melanoma can most likely emerge in all forms of acquired or congenital nevus, although documentation of a distinct, unequivocal area of melanoma arising at the junction in an indisputable Spitz nevus has never been shown, to our knowledge.