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Nasal Physiology and Pathophysiology of Nasal Disorders pp 15–25Cite as

Cilia, Ciliary Movement, and Mucociliary Transport

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Abstract

Cilia are extensions of the apical membranes. The cilium itself is characterized by a 9 + 2 axonemal structure. An active, coordinated ciliary beating is essential for mucociliary transport. Ciliary beating depends on the ATPase activity in the dynein arms and is characterized by a specific beating pattern. In healthy persons, 95 % of the cilia are ultrastructurally completely normal. Ciliary abnormalities can be the results of external factors (secondary ciliary dyskinesia) or inherited (primary ciliary dyskinesia). Ciliary function and structure are organized at different levels from the individual cilia, over interciliary and intercellular interaction, to the macroscopic level of the ciliated tapestry and mucociliary transport.

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Authors and Affiliations

  1. ENT Department, University Hospitals Leuven, Herestraat 49, Leuven, B-3000, Belgium

    Mark Jorissen MD, PhD & Martine Jaspers MSc

Authors
  1. Mark Jorissen MD, PhD
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  2. Martine Jaspers MSc
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Correspondence to Mark Jorissen MD, PhD .

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Editors and Affiliations

  1. Dept. of Otorhinolaryngology, Hacettepe University Faculty of Medicine, Ankara, Turkey

    T. Metin Önerci

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Jorissen, M., Jaspers, M. (2013). Cilia, Ciliary Movement, and Mucociliary Transport. In: Önerci, T. (eds) Nasal Physiology and Pathophysiology of Nasal Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37250-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-37250-6_2

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  • Online ISBN: 978-3-642-37250-6

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