Skip to main content

Interstitial Lung Disease in Collagen Vascular Disease

  • Chapter
  • First Online:
Radiology Illustrated: Chest Radiology

Part of the book series: Radiology Illustrated ((RADILL))

  • 4914 Accesses

Abstract

Collagen vascular diseases (CVDs) showing features of interstitial lung disease (ILD) pattern include systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), progressive systemic sclerosis (PSS), dermatomyositis (DM) and polymyositis (PM), ankylosing spondylitis (AS), Sjögren’s syndrome, and mixed connective tissue disease (MCTD). Histopathologically, interstitial lung diseases associated with CVD are diverse and include nonspecific interstitial pneumonia (NSIP), usual interstitial pneumonia (UIP), cryptogenic organizing pneumonia (COP), apical fibrosis, diffuse alveolar damage (DAD), and lymphoid interstitial pneumonia (LIP) patterns (Tables 28.1 and 28.2). NSIP accounts for large proportion, especially in PSS, DM and PM, and MCTD. More favorable prognosis in interstitial pneumonia associated with CVDs than in idiopathic interstitial pneumonias (IIPs) may be explained by the larger proportion of NSIP pattern than UIP pattern. Thin-section CT (TSCT) seems to help characterize and determine the extent of ILD in CVDs [1].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Kim EA, Lee KS, Johkoh T, et al. Interstitial lung diseases associated with collagen vascular diseases: radiologic and histopathologic findings. Radiographics. 2002;22(Spec No):S151–65.

    Article  PubMed  Google Scholar 

  2. Cervera R, Khamashta MA, Font J, et al. Systemic lupus erythematosus: clinical and immunologic patterns of disease expression in a cohort of 1,000 patients. The European Working Party on Systemic Lupus Erythematosus. Medicine (Baltimore). 1993;72:113–24.

    CAS  Google Scholar 

  3. Mayberry JP, Primack SL, Muller NL. Thoracic manifestations of systemic autoimmune diseases: radiographic and high-resolution CT findings. Radiographics. 2000;20:1623–35.

    Article  PubMed  CAS  Google Scholar 

  4. Haupt HM, Moore GW, Hutchins GM. The lung in systemic lupus erythematosus. Analysis of the pathologic changes in 120 patients. Am J Med. 1981;71:791–8.

    Article  PubMed  CAS  Google Scholar 

  5. Bankier AA, Kiener HP, Wiesmayr MN, et al. Discrete lung involvement in systemic lupus erythematosus: CT assessment. Radiology. 1995;196:835–40.

    PubMed  CAS  Google Scholar 

  6. Fenlon HM, Doran M, Sant SM, Breatnach E. High-resolution chest CT in systemic lupus erythematosus. AJR Am J Roentgenol. 1996;166:301–7.

    Article  PubMed  CAS  Google Scholar 

  7. Jurik AG, Davidsen D, Graudal H. Prevalence of pulmonary involvement in rheumatoid arthritis and its relationship to some characteristics of the patients. A radiological and clinical study. Scand J Rheumatol. 1982;11:217–24.

    Article  PubMed  CAS  Google Scholar 

  8. Gabbay E, Tarala R, Will R, et al. Interstitial lung disease in recent onset rheumatoid arthritis. Am J Respir Crit Care Med. 1997;156:528–35.

    Article  PubMed  CAS  Google Scholar 

  9. Anaya JM, Diethelm L, Ortiz LA, et al. Pulmonary involvement in rheumatoid arthritis. Semin Arthritis Rheum. 1995;24:242–54.

    Article  PubMed  CAS  Google Scholar 

  10. Yousem SA, Colby TV, Carrington CB. Lung biopsy in rheumatoid arthritis. Am Rev Respir Dis. 1985;131:770–7.

    PubMed  CAS  Google Scholar 

  11. Aratake K, Eguchi K, Migita K, et al. An autopsy case of rheumatoid arthritis accompanied with acute exacerbation of interstitial pneumonia. Nihon Rinsho Meneki Gakkai Kaishi. 1998;21:129–36.

    Article  PubMed  CAS  Google Scholar 

  12. Remy-Jardin M, Remy J, Cortet B, Mauri F, Delcambre B. Lung changes in rheumatoid arthritis: CT findings. Radiology. 1994;193:375–82.

    PubMed  CAS  Google Scholar 

  13. Akira M, Sakatani M, Hara H. Thin-section CT findings in rheumatoid arthritis-associated lung disease: CT patterns and their courses. J Comput Assist Tomogr. 1999;23:941–8.

    Article  PubMed  CAS  Google Scholar 

  14. Muller-Leisse C, Bussmann A, Meyer O, Vorbruggen W, Genth E, Gunther RW. Pulmonary manifestations in rheumatoid arthritis: high-resolution computed tomography in correlation with the skeletal changes and the laboratory chemical changes. Rofo. 1996;165:438–44.

    Article  PubMed  CAS  Google Scholar 

  15. Minai OA, Dweik RA, Arroliga AC. Manifestations of scleroderma pulmonary disease. Clin Chest Med. 1998;19:713–31; viii–ix.

    Article  PubMed  CAS  Google Scholar 

  16. Arroliga AC, Podell DN, Matthay RA. Pulmonary manifestations of scleroderma. J Thorac Imaging. 1992;7:30–45.

    Article  PubMed  CAS  Google Scholar 

  17. Muir TE, Tazelaar HD, Colby TV, Myers JL. Organizing diffuse alveolar damage associated with progressive systemic sclerosis. Mayo Clin Proc. 1997;72:639–42.

    PubMed  CAS  Google Scholar 

  18. Warrick JH, Bhalla M, Schabel SI, Silver RM. High resolution computed tomography in early scleroderma lung disease. J Rheumatol. 1991;18:1520–8.

    PubMed  CAS  Google Scholar 

  19. Remy-Jardin M, Remy J, Wallaert B, Bataille D, Hatron PY. Pulmonary involvement in progressive systemic sclerosis: sequential evaluation with CT, pulmonary function tests, and bronchoalveolar lavage. Radiology. 1993;188:499–506.

    PubMed  CAS  Google Scholar 

  20. Kim EA, Johkoh T, Lee KS, et al. Interstitial pneumonia in progressive systemic sclerosis: serial high-resolution CT findings with functional correlation. J Comput Assist Tomogr. 2001;25:757–63.

    Article  PubMed  CAS  Google Scholar 

  21. Akira M, Sakatani M, Ueda E. Idiopathic pulmonary fibrosis: progression of honeycombing at thin-section CT. Radiology. 1993;189:687–91.

    PubMed  CAS  Google Scholar 

  22. Tazelaar HD, Viggiano RW, Pickersgill J, Colby TV. Interstitial lung disease in polymyositis and dermatomyositis. Clinical features and prognosis as correlated with histologic findings. Am Rev Respir Dis. 1990;141:727–33.

    Article  PubMed  CAS  Google Scholar 

  23. Schwarz MI. The lung in polymyositis. Clin Chest Med. 1998;19:701–12; viii.

    Article  PubMed  CAS  Google Scholar 

  24. Ikezoe J, Johkoh T, Kohno N, Takeuchi N, Ichikado K, Nakamura H. High-resolution CT findings of lung disease in patients with polymyositis and dermatomyositis. J Thorac Imaging. 1996;11:250–9.

    Article  PubMed  CAS  Google Scholar 

  25. Mino M, Noma S, Taguchi Y, Tomii K, Kohri Y, Oida K. Pulmonary involvement in polymyositis and dermatomyositis: sequential evaluation with CT. AJR Am J Roentgenol. 1997;169:83–7.

    Article  PubMed  CAS  Google Scholar 

  26. Akira M, Hara H, Sakatani M. Interstitial lung disease in association with polymyositis-dermatomyositis: long-term follow-up CT evaluation in seven patients. Radiology. 1999;210:333–8.

    Article  PubMed  CAS  Google Scholar 

  27. Cain HC, Noble PW, Matthay RA. Pulmonary manifestations of Sjogren’s syndrome. Clin Chest Med. 1998;19:687–99; viii.

    Article  PubMed  CAS  Google Scholar 

  28. Johkoh T, Muller NL, Pickford HA, et al. Lymphocytic interstitial pneumonia: thin-section CT findings in 22 patients. Radiology. 1999;212:567–72.

    Article  PubMed  CAS  Google Scholar 

  29. Franquet T, Gimenez A, Monill JM, Diaz C, Geli C. Primary Sjogren’s syndrome and associated lung disease: CT findings in 50 patients. AJR Am J Roentgenol. 1997;169:655–8.

    Article  PubMed  CAS  Google Scholar 

  30. Koyama M, Johkoh T, Honda O, et al. Pulmonary involvement in primary Sjogren’s syndrome: spectrum of pulmonary abnormalities and computed tomography findings in 60 patients. J Thorac Imaging. 2001;16:290–6.

    Article  PubMed  CAS  Google Scholar 

  31. Meyer CA, Pina JS, Taillon D, Godwin JD. Inspiratory and expiratory high-resolution CT findings in a patient with Sjogren’s syndrome and cystic lung disease. AJR Am J Roentgenol. 1997;168:101–3.

    Article  PubMed  CAS  Google Scholar 

  32. Ichikawa Y, Kinoshita M, Koga T, Oizumi K, Fujimoto K, Hayabuchi N. Lung cyst formation in lymphocytic interstitial pneumonia: CT features. J Comput Assist Tomogr. 1994;18:745–8.

    Article  PubMed  CAS  Google Scholar 

  33. Prakash UB. Lungs in mixed connective tissue disease. J Thorac Imaging. 1992;7:55–61.

    Article  PubMed  CAS  Google Scholar 

  34. Prakash UB. Respiratory complications in mixed connective tissue disease. Clin Chest Med. 1998;19:733–46; ix.

    Article  PubMed  CAS  Google Scholar 

  35. Lee-Chiong Jr TL. Pulmonary manifestations of ankylosing spondylitis and relapsing polychondritis. Clin Chest Med. 1998;19:747–57; ix.

    Article  PubMed  Google Scholar 

  36. Casserly IP, Fenlon HM, Breatnach E, Sant SM. Lung findings on high-resolution computed tomography in idiopathic ankylosing spondylitis–correlation with clinical findings, pulmonary function testing and plain radiography. Br J Rheumatol. 1997;36:677–82.

    Article  PubMed  CAS  Google Scholar 

  37. Fenlon HM, Casserly I, Sant SM, Breatnach E. Plain radiographs and thoracic high-resolution CT in patients with ankylosing spondylitis. AJR Am J Roentgenol. 1997;168:1067–72.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Lee, K.S., Han, J., Chung, M.P., Jeong, Y.J. (2014). Interstitial Lung Disease in Collagen Vascular Disease. In: Radiology Illustrated: Chest Radiology. Radiology Illustrated. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37096-0_28

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-37096-0_28

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-37095-3

  • Online ISBN: 978-3-642-37096-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics