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Polysaccharide-Based Graft Copolymers for Biomedical Applications

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Polysaccharide Based Graft Copolymers

Abstract

Polysaccharides play an important role in the field of science and technology because of their unique properties. The polysaccharides are available from natural and microbial resources. They are biodegradable as well as nontoxic. Water soluble polymers based on grafted polysaccharides have drawn much attention in recent decades because of their controlled biodegradability, shear stability, and high efficiency in various applications. One of the important applications of polysaccharide-based graft copolymers is in biomedical science—as matrix for controlled/targeted drug delivery. It is observed in authors’ laboratory that rate of release of enclosed drug can be precisely controlled by controlling the grafting/cross-linking efficiency. Thus tailor-made grafted polysaccharides have potential application in drug delivery research. This chapter deals with the techniques employed for the synthesis of grafted polysaccharides, and recent developments took place in author’s laboratory based on application of grafted polysaccharides in controlled/targeted drug delivery.

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Acknowledgment

The authors are grateful to Indian School of Mines, Dhanbad, India, for providing necessary facilities to carry out the reported drug delivery study. The authors also earnestly acknowledge the financial support from University Grants Commissions, New Delhi, India, in form of a research grant [No. 36-59/2008 (SR)].

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  1. Polymer Chemistry Laboratory, Department of Applied Chemistry, Indian School of Mines, Dhanbad, Jharkhand, 826004, India

    Sagar Pal & Raghunath Das

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  1. Sagar Pal
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  2. Raghunath Das
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Correspondence to Sagar Pal .

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  1. Dept. of Chemistry, Bahra University, Waknaghat, Himachal Pradesh, 173 229, India

    Susheel Kalia

  2. , Chemistry Dept. Faculty of Science, Cairo University, Gamaa Street, Giza, 12613, Egypt

    M.W. Sabaa

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© 2013 Springer-Verlag Berlin Heidelberg

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Pal, S., Das, R. (2013). Polysaccharide-Based Graft Copolymers for Biomedical Applications. In: Kalia, S., Sabaa, M. (eds) Polysaccharide Based Graft Copolymers. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36566-9_9

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