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Patient Selection and Recommendations: HDR

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Interstitial Prostate Brachytherapy
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Abstract

Patient selection criteria are very similar to that of LDR implants; there are fewer differences in the list of preoperative investigations and more in patient selection for both combined HDR and external beam treatment and HDR monotherapy. Recommendations for necessary equipment, interdisciplinary team, dose prescription, treatment documentation, and quality control are given.

New trends and investigational methods (focal therapy, salvage treatments) are discussed including the role of antiandrogen treatments.

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References

  • Allen GW, Howard AR, Jarrad DF et al (2007) Management of prostate cancer recurrences after radiation therapy – brachytherapy as a salvage option. Cancer 110:1405–1416

    Article  PubMed  Google Scholar 

  • Ash D, Flynn A, Battermann J et al (2000) ESTRO/EAU/EORTC recommendations on permanent seed implantation for localized prostate cancer. Radiother Oncol 57:315–321

    Article  PubMed  CAS  Google Scholar 

  • Bertermann H, Brix F (1990) Ultrasonically guided interstitial high dose rate brachytherapy with Ir-192: technique and preliminary results in locally confined prostate cancer. In: Martinez AA, Orton CF, Mould RF (eds) Brachytherapy HDR and LDR: remote afterloading state of the art. Nucletron International BV, Leersum, pp 281–303

    Google Scholar 

  • Bolla M, Gonsales D, Warde P et al (1997) Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin. N Engl J Med 337:295–300

    Article  PubMed  CAS  Google Scholar 

  • Borghede G, Hedelin H, Holmang S et al (1997) Combined treatment with temporary short-term high dose rate iridium-192 brachytherapy and external beam radiotherapy for irradiation of localized prostatic carcinoma. Radiother Oncol 44:237–244

    Article  PubMed  CAS  Google Scholar 

  • De la Rosette JJMCH, Wink MH, Mamoulakis C et al (2009) Optimization of prostate cancer detection in a clinical population: results from an eight versus 12-core transrectal ultrasound guided biopsy protocol. J Urol 182(4):1329

    Article  PubMed  Google Scholar 

  • De la Rosette JJMCH, Ahmed HJ, Barentsz J, Barentsz T (2010) Focal therapy in prostate cancer—report from a consensus panel. J Endourol 24(5):775–780

    Article  PubMed  Google Scholar 

  • Demanes DJ, Rodrigues RR, Altieri GA (2000) High dose rate prostate brachytherapy: the California endocurietherapy (CET) method. Radiother Oncol 57:289–296

    Article  PubMed  CAS  Google Scholar 

  • Demanes DJ, Gilhezan M, Schour L et al (2007) High dose rate brachytherapy (HDR-BT) as monotherapy for favorable prostate cancer: excellent 5-year control rates and low toxicity. Int J Radiat Oncol Biol Phys 69:S83

    Article  Google Scholar 

  • Dinges S, Deger S, Koswig S et al (1998) High dose rate interstitial brachytherapy combined with external beam irradiation for localized prostate cancer—a prospective study. Radiother Oncol 48:197–203

    Article  PubMed  CAS  Google Scholar 

  • Egevad L, Granfors T, Karlberg L et al (2002) Prognostic value of the Gleason score in prostate cancer. BJU Int 89(6):538–542

    Article  PubMed  CAS  Google Scholar 

  • Heidenreich A, Bellmunt J, Bolla M et al (2011) EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localized disease. Eur Urol 59:61–71

    Article  PubMed  Google Scholar 

  • Hinkelbein W (1998) Adjuvant or therapeutic androgen suppression in locoregional advanced prostatic carcinoma (RTOG 85–31) [Article in German]. Strahlenther Onkol 174:385–386

    Article  PubMed  CAS  Google Scholar 

  • Hoskin P, Rojas A, Lowe G et al (2011) High-dose-rate brachytherapy alone for localized prostate cancer in patients at a moderate or high risk of biochemical recurrence. J Radiat Oncol Biol Phys. doi:10.1016/j.ijrobp.2011.04.031

  • http://cancer.beaumont.edu/beaumont-launches-prostate-cancer-study-single-dose-radiation-treatment. Accessed 25 Aug 2011

  • ICRU Report 58 (1997) Dose and volume specification for reporting interstitial brachytherapy, International Commission on Radiation Units and Measurements, ICRU, Bethesda

    Google Scholar 

  • Kovács G, Galalae R, Wirth B et al (1995) Optimization of interstitial brachytherapy by a new implant technique in the treatment of prostate cancer (ger). Strahlenther Onkol 171:685–688

    PubMed  Google Scholar 

  • Kovács G, Pötter R, Loch T et al (2005) GEC/ESTRO-EAU recommendations on temporary brachytherapy using stepping sources for localized prostate cancer. Radiother Oncol 74:137–148

    Article  PubMed  Google Scholar 

  • Kovács G, Melchert C, Sommerauer M et al (2007) Intensity modulated high-dose-rate brachytherapy boost complementary to external beam radiation for intermediate- and high-risk localized prostate cancer patients – how we do it in Luebeck/Germany. Brachytherapy 6:142–148

    Article  PubMed  Google Scholar 

  • Krauss D, Kestin L, Ye H et al (2011) Lack of benefit for the addition of androgen deprivation therapy to dose-escalated radiotherapy in the treatment of intermediate- and high-risk prostate cancer. Int J Radiat Oncol Biol Phys 80(4):1064–1071

    Article  PubMed  Google Scholar 

  • Kronz JD, Milord R, Wilentz R, Weir EG, Schreiner SR, Epstein JI (2003) Lesions missed on prostate biopsies in cases sent in for consultation. Prostate 54(4):310–314

    Article  PubMed  Google Scholar 

  • Lawton CA, Winter K, Murray K et al (2001) Updated results of the phase III Radiation Therapy Oncology Group (RTOG) trial 85–31 evaluating the potential benefit of androgen suppression following standard radiation therapy for unfavourable prognosis carcinoma of the prostate. Int J Radiat Oncol Biol Phys 49:937–946

    Article  PubMed  CAS  Google Scholar 

  • Lee B, Shinohara K, Weinberg V et al (2007) Feasibility of high-dose-rate brachytherapy salvage for local prostate cancer recurrence after radiotherapy: the University of California-San Francisco experience. Int J Radiat Oncol Biol Phys 67(4):1106–1112

    Article  PubMed  Google Scholar 

  • Mark RJ, Akins RS, Anderson PJ et al (2007) Interstitial high dose rate (HDR) brachytherapy as monotherapy for early stage prostate cancer: a report of 206 cases. Int J Radiat Oncol Biol Phys 69:S329

    Article  Google Scholar 

  • Martinez AA, Gonzalez J, Stromberg J et al (1995) Conformal prostate brachytherapy: initial experience of a phase I/II dose-escalating trial. Int J Radiat Oncol Biol Phys 33:1019–1027

    Article  PubMed  CAS  Google Scholar 

  • Martinez AA, Demanes J, Vargas C et al (2010) High-dose-rate prostate brachytherapy: an excellent accelerated-hypofractionated treatment for favorable prostate cancer. Am J Clin Oncol 33:481–488

    Article  PubMed  Google Scholar 

  • Polascik TJ, Mouraviev V (2008) Focal therapy for prostate cancer. Curr Opin Urol 18:269

    Article  PubMed  Google Scholar 

  • Salambier C, Lavagnini P, Nickers P et al (2007) Tumour and target volumes in permanent prostate brachytherapy: a supplement to the ESTRO/EAU/EORTC recommendations on prostate brachytherapy. Radiother Oncol 83:3–10

    Article  Google Scholar 

  • Vicini FA, Martinez AA, Hanks G et al (2002) An interinstitutional and interspecialty comparison of treatment outcome data for patients with prostate carcinoma based on predefined prognostic categories and minimum follow-up. Cancer 95:2126–2135

    Article  PubMed  Google Scholar 

  • Vicini FA, Shah C, Kestin L et al (2011) Identifying differences between biochemical failure and cure: incidence rates and predictors. Int J Radiat Oncol Biol Phys. doi:10.1016/j.ijrobp.2011.05.017

  • Wallner K (2002) Prostate brachytherapy under local anesthesia: lessons from the first 600 patients. Brachytherapy 1:145–148

    Article  PubMed  Google Scholar 

  • Watanabe H, Igari D, Tanahasi Y et al (1974) Development and application of new equipment for transrectal ultrasonography. J Clin Ultrasound 2:91–98

    Article  PubMed  CAS  Google Scholar 

  • Yoshioka Y, Konishi K, Oh RJ et al (2006) High-dose-rate brachytherapy without external beam irradiation for locally advanced prostate cancer. Radiother Oncol 80:62–68

    Article  PubMed  Google Scholar 

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Correspondence to György Kovács .

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Kovács, G. (2013). Patient Selection and Recommendations: HDR. In: Kovács, G., Hoskin, P. (eds) Interstitial Prostate Brachytherapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36499-0_5

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  • DOI: https://doi.org/10.1007/978-3-642-36499-0_5

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