Nomenclature
EC number
2.1.1.171
Systematic name
S-adenosyl-l-methionine:16S rRNA (guanine966-N2)-methyltransferase
Recommended name
16S rRNA (guanine966-N2)-methyltransferase
Synonyms
16S rRNA-specific methyltransferases m2GMT <1> [4]
RNA:(guanine-N2) methyltransferase RsmD <1> [3]
RsmD <1> (<1> gene name [1,2]) [1,2]
m2G966 methyltransferase <1> [1,4]
yhhF <1> (<1> gene name [1,2]) [1,2]
CAS registry number
50812-26-5
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References
Lesnyak, D.V.; Osipiuk, J.; Skarina, T.; Sergiev, P.V.; Bogdanov, A.A.; Edwards, A.; Savchenko, A.; Joachimiak, A.; Dontsova, O.A.: Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure. J. Biol. Chem., 282, 5880-5887 (2007)
Sergiev, P.V.; Bogdanov, A.A.; Dontsova, O.A.: Ribosomal RNA guanine-(N2)- methyltransferases and their targets. Nucleic Acids Res., 35, 2295-2301 (2007)
Bujnicki, J.M.: Rychlewski. L.: RNA:(guanine-(N2)) methyltransferases RsmC/ RsmD and their homologs revisited–bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure. BMC Bioinformatics, 3, 0000 (2002)
Weitzmann, C.; Tumminia, S.J.; Boublik, M.; Ofengand, J.: A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of 57 is required for methylation of m2G966 and blocks methylation of m C967 by their respective methyltransferases. Nucleic Acids Res., 19, 7089-7095 (1991)
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Schomburg, D., Schomburg, I. (2013). 16S rRNA (guanine966-N2)-methyltransferase 2.1.1.171. In: Schomburg, D., Schomburg, I. (eds) Class 2–3.2 Transferases, Hydrolases. Springer Handbook of Enzymes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36240-8_9
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