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Osteonecrosis: Historical Perspective

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Osteonecrosis

Abstract

Osteonecrosis, also known as avascular necrosis, ischemic necrosis, and aseptic necrosis, is not a specific disease entity. It is rather a condition in which a circumscribed area of bone becomes necrotic as a result of the loss of its blood supply. The most common cause is trauma, a displaced fracture or dislocation which results in a mechanical injury to the local vessels. However, many etiologic factors unrelated to trauma have also been identified. The femoral head is the region most often affected, but the proximal humerus, femoral condyles, and small bones of the hands and feet may also be involved. Despite considerable progress in the study of this condition, there is still much to be learned about its etiology, pathogenesis, and treatment.

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Steinberg, M.E., Steinberg, D.R. (2014). Osteonecrosis: Historical Perspective. In: Koo, KH., Mont, M., Jones, L. (eds) Osteonecrosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35767-1_1

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