Skip to main content
SpringerLink
Log in

SPECT/CT in Sentinel Node Scintigraphy

  • Chapter
  • First Online:
Clinical Applications of SPECT-CT

  • 1630 Accesses

Abstract

With the introduction of the sentinel node (SN) procedure more than 20 years ago, lymphoscintigraphy became an essential component for lymphatic mapping and preoperative SN identification in melanoma and breast cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Morton DL, Wen DR, Wong JH, Economou JS, Cagle LA, Storm FK, et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg. 1992;127:392–9.

    Article  PubMed  CAS  Google Scholar 

  2. Sobin LH. TNM, sixth edition: new developments in general concepts and rules. Semin Surg Oncol. 2003;21:19–22.

    Article  PubMed  Google Scholar 

  3. Delbeke D, Coleman RE, Guiberteau MJ, Brown ML, Royal HD, Siegel BA, et al. Procedure guidelines for SPECT/CT imaging. J Nucl Med. 2006;47:1227–34.

    PubMed  Google Scholar 

  4. Fishman EK, Ney DR, Heath DG, Corl FM, Horton KM, Johnson PT. Volume rendering versus maximum intensity projection in CT angiography: what works best, when, and why. Radiographics. 2006;26:905–22.

    Article  PubMed  Google Scholar 

  5. Vidal-Sicart S, Brouwer OR, Valdés Olmos RA. Evaluation of the sentinel lymph node combining SPECT/CT with the planar images and its importance for the surgical act. Rev Esp Med Nucl. 2011;30:331–7.

    Article  PubMed  CAS  Google Scholar 

  6. Nieweg OE, Estourgie S, Valdés Olmos RA. Lymphatic mapping and sentinel node biopsy. In: Ell PJ, Gambhir SS, editors. Nuclear medicine in clinical diagnosis and treatment. 3rd ed. Edinburgh: Churchill Livingstone; 2004. p. 229–60.

    Google Scholar 

  7. Alazraki N, Glass EC, Castronovo F, Valdés Olmos RA, Podoloff D. Procedure guideline for lymphoscintigraphy and the use of intraoperative gamma probe for sentinel lymph node localization in melanoma of intermediate thickness 1.0. J Nucl Med. 2002;43:1414–8.

    PubMed  Google Scholar 

  8. Van der Ploeg IM, Valdés Olmos RA, Kroon BBR, Wouters MWJM, van den Brekel MWM, Vogel WV, et al. The yield of SPECT/CT for anatomical lymphatic mapping in patients with melanoma. Ann Surg Oncol. 2009;16:1537–42.

    Article  PubMed  Google Scholar 

  9. Mucientes Rasilla J, Cardona Arbonies J, Delgado Bolton R, Izarduy Pereyra L, Salazar Andia G, Prieto Soriano A, et al. SPECT-CT in sentinel node detection in patients with melanoma. Rev Esp Med Nucl. 2009;28:229–34.

    Article  PubMed  CAS  Google Scholar 

  10. Veenstra HJ, Vermeeren L, Valdés Olmos RA, Nieweg OE. The additional value of lymphatic mapping with routine SPECT/CT in unselected patients with clinically localized melanoma. Ann Surg Oncol. 2012;19:1018–23.

    Article  PubMed  Google Scholar 

  11. Stoffels I, Boy C, Pöppel T, Kuhn J, Klötgen K, Dissemond J, et al. Association between lymph node excision with or without preoperative SPECT/CT and metastatic node detection and disease-free survival in melanoma. JAMA. 2012;308:1007–14.

    Article  PubMed  CAS  Google Scholar 

  12. Van der Ploeg IM, Nieweg OE, Kroon BB, Rutgers EJ, Baas-Vrancken Peeters MJ, Vogel WV, et al. The yield of SPOECT/CT for anatomical lymphatic mapping in patients with breast cancer. Eur J Nucl Med Mol Imaging. 2009;36:903–9.

    Article  PubMed  Google Scholar 

  13. Husarik DB, Steinert HC. Single-photon emission computed tomography/computed tomography for sentinel node mapping in breast cancer. Semin Nucl Med. 2007;37:29–33.

    Article  PubMed  Google Scholar 

  14. Leman H, Lievshitz G, Zak O, Metser U, Schneebaum S, Even-Sapir E. Improved sentinel node identification by SPECT/CT in overweight patients with breast cancer. J Nucl Med. 2007;28:201–6.

    Google Scholar 

  15. Leman H, Metser U, Lievshitz G, Sperber F, Shneebaum S, Even-Sapir E. Lymphoscintigraphic sentinel node identification in patients with breast cancer: the role of SPECT/CT. Eur J Nucl Med Mol Imaging. 2006;33:329–37.

    Article  Google Scholar 

  16. Gallowitsch HJ, Kraschi P, Igerc I, Hussein T, Kresnik E, Mikosch P, et al. Sentinel node SPECT-CT in breast cancer. Can we expect any additional and clinically relevant information? Nuklearmedizin. 2007;46:252–6.

    PubMed  Google Scholar 

  17. Haerle SK, Hany TF, Strobel K, Sidler D, Stoeckli SJ. Is there an additional value of SPECT/CT over planar lymphoscintigraphy for sentinel node mapping in oral/oropharyngeal squamous cell carcinoma? Ann Surg Oncol. 2009;16:3118–24.

    Article  PubMed  Google Scholar 

  18. Bilde A, Von Buchwald C, Mortensen J, Marving J, Hamilton Therkildsen M, Kirkegaard J, et al. The role of SPECT-CT in the lymphoscintigraphic identification of sentinel nodes in patients with oral cancer. Acta Otolaryngol. 2006;126:1096–103.

    Article  PubMed  Google Scholar 

  19. Vermeeren L, Valdés Olmos RA, Klop MC, van der Ploeg IMC, Nieweg OE, Balm AJM, et al. SPECT/CT for sentinel lymph node mapping in head and neck melanoma. Head Neck. 2011;33:1–6.

    Article  PubMed  Google Scholar 

  20. Klode J, Poeppel T, Boy C, Mueller S, Schadendorf D, Korber A, et al. Advantages of preoperative hybrid SPECT/CT in detection of sentinel lymph nodes in cutaneous head and neck malignancies. J Eur Acad Dermatol Venereol. 2011;25:1213–21.

    Article  PubMed  CAS  Google Scholar 

  21. Vermeeren L, Valdés Olmos RA, Meinhardt W, Bex A, van der Poel HG, Vogel WW, et al. Value of SPECT/CT for detection and anatomic localization of sentinel lymph nodes before laparoscopic sentinel node lymphadenectomy in prostate cancer. J Nucl Med. 2009;50:865–70.

    Article  PubMed  Google Scholar 

  22. Meinhardt W, van der Poel HG, Valdés Olmos RA, Bex A, Brouwer OR, Horenblas S. Laparoscopic sentinel lymph node biopsy for prostate cancer: the relevance of locations outside the extended dissection area. Prostate Cancer. 2012;2012:751753.

    Article  PubMed  CAS  Google Scholar 

  23. Vermeeren L, Meinhardt W, van der Poel HG, Valdés Olmos RA. Lymphatic drainage from the treated versus untreated prostate: feasibility of sentinel node biopsy in recurrent cancer. Eur J Nucl Med Mol Imaging. 2010;37:2012–26.

    Google Scholar 

  24. Krengli M, Ballare A, Cannillo B, Rudoni M, Kocjancic E, Loi G, et al. Potential advantage of studying the lymphatic drainage by sentinel node technique and SPECT/CT image fusion for pelvic irradiation of prostate cancer. Int J Radiat Oncol Biol Phys. 2006;66:1100–4.

    Article  PubMed  Google Scholar 

  25. Brouwer OR, Valdés Olmos RA, Vermeeren L, Hoefnagel CA, Nieweg OE, Horenblas S. SPECT/CT and a portable γ-camera for image-guided laparoscopic sentinel node biopsy in testicular cancer. J Nucl Med. 2011;52:5551–4.

    Google Scholar 

  26. Bex A, Vermeeren L, Meinhardt W, Prevoo W, Horenblas S, Valdés Olmos RA. Intraoperative sentinel node identification and sampling in clinically node-negative renal cell carcinoma: initial experience in 20 patients. World J Urol. 2011;29:793–9.

    Article  PubMed  CAS  Google Scholar 

  27. Martinez A, Zerdoud S, Mery E, Bouissou E, Ferron G, Querleu D. Hybrid imaging by SPECT/CT for sentinel lymph node detection in patients with cancer of the uterine cervix. Gynecol Oncol. 2010;119:431–5.

    Article  PubMed  CAS  Google Scholar 

  28. Perissinotti A, Paredes P, Vidal-Sicart S, Torné A, Albela S, Navales I, et al. Use of SPECT/CT for improved sentinel lymph node localization in endometrial cancer. Gynecol Oncol. 2013;129:42–8.

    Article  PubMed  CAS  Google Scholar 

  29. Nomori H, Ikeda K, Mori T, Shiraishi S, Kobayashi H, Kawanaka K, et al. Sentinel node identification in clinical stage Ia non-small lung cancer by a combined single photon emission computed tomography/computed tomography system. J Thorac Cardiovasc Surg. 2007;134:182–7.

    Article  PubMed  Google Scholar 

  30. Van der Ploeg IM, Valdés Olmos RA, Nieweg OE, Rutgers EJ, Kroon BB, Hoefnagel CA. The additional value of SPECT/CT in lymphatic mapping in breast cancer and melanoma. J Nucl Med. 2007;48:1756–60.

    Article  PubMed  Google Scholar 

  31. Vermeeren L, van der Ploeg IM, Valdés Olmos RA, Meinhardt W, Klop WM, Kroon BB, et al. SPECT/CT for preoperative sentinel node localization. J Surg Oncol. 2010;101:184–90.

    PubMed  Google Scholar 

  32. Vermeeren L, Valdés Olmos RA, Klop WM, Balm AJ, van den Brekel MW. A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region. J Nucl Med. 2010;51:700–3.

    Article  PubMed  Google Scholar 

  33. Valdés Olmos RA, Vidal-Sicart S, Nieweg OE. Technological innovation in the sentinel node procedure: towards 3-D intraoperative imaging. Eur J Nucl Med Mol Imaging. 2010;37:1449–51.

    Article  PubMed  Google Scholar 

  34. Brouwer OR, Buckle T, Bunschoten A, Kuil J, Vahrmeijer AL, Wendler T, et al. Image navigation as a means to expand the boundaries of fluorescence-guided surgery. Phys Med Biol. 2012;57:2123–3136.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nuclear Medicine Department, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands

    Renato A. Valdés Olmos & Oscar R. Brouwer

  2. Interventional Molecular Imaging Laboratory, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands

    Renato A. Valdés Olmos

  3. Nuclear Medicine Department, University Hospital Clinic, Villaroel 170, 08036, Barcelona, Spain

    Sergi Vidal-Sicart

Authors
  1. Renato A. Valdés Olmos
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Oscar R. Brouwer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sergi Vidal-Sicart
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Renato A. Valdés Olmos .

Editor information

Editors and Affiliations

  1. Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany

    Hojjat Ahmadzadehfar

  2. Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany

    Hans-Jürgen Biersack

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Olmos, R.A.V., Brouwer, O.R., Vidal-Sicart, S. (2014). SPECT/CT in Sentinel Node Scintigraphy. In: Ahmadzadehfar, H., Biersack, HJ. (eds) Clinical Applications of SPECT-CT. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35283-6_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-35283-6_10

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-35282-9

  • Online ISBN: 978-3-642-35283-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation