Abstract
Following the introduction of therapeutic hypothermia and the implementation of standardized post-resuscitation care, the number of patients who survive from coma after cardiac arrest has significantly increased [1]. Previous to use of therapeutic hypothermia, clinical neurological examination at 72 hours was considered the gold standard for outcome prognostication of coma after cardiac arrest [2]. However, therapeutic hypothermia and the drugs used to induce therapeutic cooling alter drug elimination and may significantly modify neurological (mainly motor) response [3, 4], thereby rendering clinical examination less reliable and potentially insufficient, when used alone, to adequately predict the prognosis of coma after cardiac arrest.
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Oddo, M. (2013). Prognostication of Coma After Cardiac Arrest and Therapeutic Hypothermia. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2013. Annual Update in Intensive Care and Emergency Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35109-9_29
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DOI: https://doi.org/10.1007/978-3-642-35109-9_29
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