Abstract
Textbook descriptions of physiological regulation systems in the human body are frequently simplified to enable application of these concepts in clinical practice. An example of a complex control system that has been simplified for clinical monitoring purposes is the maintenance of tissue perfusion. Although tissue perfusion depends on local vasomotor tone, metabolic regulation and cardiac output, perioperative monitoring is in most cases restricted to non-invasive arterial blood pressure measurements in combination with heart rate and oxygen saturation in patients undergoing low risk surgery. The use of more specific indices for tissue perfusion and fluid responsiveness, such as stroke volume, cardiac output, oxygen delivery and consumption, stroke volume variation (SVV) and pulse pressure variation (PPV), is generally restricted to the intensive care setting and high-risk surgical procedures, mainly due to the vulnerability of these specific patient populations.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Brassard P, Seifert T, Wissenberg M, Jensen PM, Hansen CK, Secher NH (2010) Phenylephrine decreases frontal lobe oxygenation at rest but not during moderately intense exercise. J Appl Physiol 108:1472–1478
Thiele RH, Nemergut EC, Lynch 3rd C (2011) The physiologic implications of isolated alpha(1) adrenergic stimulation. Anesth Analg 113:284–296
Meng L, Cannesson M, Alexander BS et al (2011) Effect of phenylephrine and ephedrine bolus treatment on cerebral oxygenation in anaesthetized patients. Br J Anaesth 107:209–217
Bellomo R, Giantomasso DD (2001) Noradrenaline and the kidney: friends or foes? Crit Care 5:294–298
Elbers PW, Ozdemir A, van Iterson M, van Dongen EP, Ince C (2009) Microcirculatory imaging in cardiac anesthesia: ketanserin reduces blood pressure but not perfused capillary density. J Cardiothorac Vasc Anesth 23:95–101
Maier S, Hasibeder WR, Hengl C et al (2009) Effects of phenylephrine on the sublingual microcirculation during cardiopulmonary bypass. Br J Anaesth 102:485–491
De Backer D, Ortiz JA, Salgado D (2010) Coupling microcirculation to systemic hemodynamics. Curr Opin Crit Care 16:250–254
Boerma EC, Ince C (2010) The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients. Intensive Care Med 36:2004–2018
Koning NJ, Vonk AB, van Barneveld LJ et al (2012) Pulsatile flow during cardiopulmonary bypass preserves postoperative microcirculatory perfusion irrespective of systemic hemodynamics. J Appl Physiol 112:1727–1734
Atasever B, Boer C, Lust E, van der Kuil M et al (2011) Quantitative imaging of microcirculatory response during nitroglycerin-induced hypotension. J Cardiothorac Vasc Anesth 25:140–144
Thooft A, Favory R, Salgado DR et al (2011) Effects of changes in arterial pressure on organ perfusion during septic shock. Crit Care 15:R222
Pottecher J, Deruddre S, Teboul JL et al (2010) Both passive leg raising and intravascular volume expansion improve sublingual microcirculatory perfusion in severe sepsis and septic shock patients. Intensive Care Med 36:1867–1874
Hamilton MA, Cecconi M, Rhodes A (2011) A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg 112:1392–1402
Gurgel ST, do Nascimento Jr P (2011) Maintaining tissue perfusion in high-risk surgical patients: a systematic review of randomized clinical trials. Anesth Analg 112:1384–1391
Lopes MR, Oliveira MA, Pereira VO, Lemos IP, Auler Jr JO, Michard F (2007) Goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery: a pilot randomized controlled trial. Crit Care 11:R100
Montenij LJ, de Waal EE, Buhre WF (2011) Arterial waveform analysis in anesthesia and critical care. Curr Opin Anaesthesiol 24:651–656
Peñáz J (1954) A portable finger plethysmograph. Scr Med (Brno) 27:213–234
Wesseling KH, De Wit B, Van der Hoeven GMA, Van Goudoever J, Settels JJ (1995) Physiocal, calibrating finger vascular physiology for Finapres. Homeostasis 36:67–82
Eeftinck Schattenkerk DW, van Lieshout JJ, van den Meiracker AH et al (2009) Nexfin noninvasive continuous blood pressure validated against Riva-Rocci/Korotkoff. Am J Hypertens 22:378–383
Martina JR, Westerhof BE, van Goudoever J et al (2012) Noninvasive continuous arterial blood pressure monitoring with Nexfin. Anesthesiology 116:1092–1103
Bogert LW, Wesseling KH, Schraa O et al (2010) Pulse contour cardiac output derived from non-invasive arterial pressure in cardiovascular disease. Anaesthesia 65:1119–1125
Garnier RP, van der Spoel AG, Sibarani-Ponsen R, Markhorst DG, Boer C (2012) Level of agreement between Nexfin non-invasive arterial pressure with invasive arterial pressure measurements in children. Br J Anaesth 109:609–615
Michard F, Biais M (2012) Rational fluid management: dissecting facts from fiction. Br J Anaesth 108:369–371
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Boer, C. (2013). Perioperative Monitoring of Tissue Perfusion: New Developments. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2013. Annual Update in Intensive Care and Emergency Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35109-9_23
Download citation
DOI: https://doi.org/10.1007/978-3-642-35109-9_23
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-35108-2
Online ISBN: 978-3-642-35109-9
eBook Packages: MedicineMedicine (R0)