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Uroonkologie pp 261–316Cite as

Komplementäre Therapieverfahren

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Zusammenfassung

Gemäß einer Definition des „National Center for Complementary and Alternative Medicine“ der National Institutes of Health (NIH) in den USA handelt es sich bei alternativmedizinischen Therapieverfahren um Maßnahmen, die an Stelle der konventionellen Therapie durchgeführt werden. Demgegenüber werden komplementärmedizinische Therapien ergänzend zur konventionellen Therapie angewendet (http://nccam.nih.gov).

Bei vielen alternativen und komplementären Therapieverfahren steht ein sicherer Wirkungsnachweis noch aus, der den wissenschaftlichen Grundlagen des etablierten Medizinsystems genügen würde. Ihre Anwendung stützt sich auf Erfahrungen, die für manche Therapiesysteme auf Jahrtausende zurückgehen. In den letzten Jahren sind jedoch einige auch für die Uroonkologie relevante Therapie- oder Präventivansätze evaluiert worden, die insbesondere im Bereich der Bewegungs- und Ernährungstherapie sowie der Mind-Body-Medizin als evidenzbasierte Verfahren zunehmend auch Anerkennung finden.

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Literatur

Literatur zu ▶ Abschn. 16.1

  • Allensbach Umfrage 7016: Naturheilmittel 2002. Insititut für Demoskopie Allensbach, Januar 2002

    Google Scholar 

  • Allensbach Umfrage: „Integrative Medizin und Traditionelle Chinesische Medizin – Ergebnisse einer repräsentativen Bevölkerungsumfrage zur Bekanntheit und Bedeutung“. Institut für Demoskopie Allensbach, August 2005

    Google Scholar 

  • Eisenberg DM, Davis RB, Ettner SL et al. (1998) Trends in alternative medicine use in the United States, 1990–1997: results of a follow-up national survey. JAMA 280: 1569–1575

    CAS  PubMed  Google Scholar 

  • Fair W (1999) Back to the future – the role of complementary medicine in urology. J Urol 162: 411–420

    CAS  PubMed  Google Scholar 

  • Nam RK, Fleshner N, Rukovitch E et al. (1999) Prevalence and patterns of the use of complementary therapies among prostate cancer patients and epidemiological analysis. J Urol 161: 1521–1524

    CAS  PubMed  Google Scholar 

  • Spahn G, Harmaring A, Lüdtke R et al. (2003) Characteristics of german cancer patients using CAM: a survey in 441 cancer patients. FACT (8): 540

    Google Scholar 

Literatur zu ▶ Abschn. 16.2

  • Ahmed S, Johnson CS, Rueger RM, Trump DL (2002) Calcitriol (1,25-dihydroxycholecalciferol) potentiates activitiy of mitoxantrone/dexamethasone in an androgen independent prostate cancer model. J Urol 168: 756–761

    CAS  PubMed  Google Scholar 

  • Ahn J, Peters U, Albanes D et al. (2008) Serum vitamin D concentration and prostate cancer risk: a nested case-control study. J Natl Cancer Inst 100 (11): 796–804

    CAS  PubMed Central  PubMed  Google Scholar 

  • Alexander DD, Mink PJ, Cushing CA, Sceurman B (2010) A review and meta-analysis of prospective studies of red and processed meat intake and prostate cancer. Nutr J 9: 50

    PubMed Central  PubMed  Google Scholar 

  • Alguacil J, Kogevinas M, Silverman DT et al. (2011) Urinary pH, cigarette smoking and bladder cancer risk. Carcinogenesis 32 (6): 843–847

    CAS  PubMed Central  PubMed  Google Scholar 

  • Alkhenizan A, Hafez K (2007) The role of vitamin E in the prevention of cancer: a meta-analysis of randomized controlled trials. Ann Saudi Med 27 (6): 409–1

    PubMed  Google Scholar 

  • Allen NE, Key TJ, González CA, Khaw KT, Riboli E et al. (2008) Animal foods, protein, calcium and prostate cancer risk: the European Prospective Investigation into Cancer and Nutrition. Br J Cancer 98 (9): 1574–1581

    CAS  PubMed Central  PubMed  Google Scholar 

  • Amaral AF, Cantor KP, Silverman DT, Malats N (2010) Selenium and bladder cancer risk: a meta-analysis. Cancer Epidemiol Biomarkers Prev 19 (9): 2407–15

    CAS  PubMed  Google Scholar 

  • Ambrosini GL, de Klerk NH, Fritschi L et al. (2008) Fruit, vegetable, vitamin A intakes, and prostate cancer risk. Prostate Cancer Prostatic Dis 11 (1): 61–6

    CAS  PubMed  Google Scholar 

  • Andersson SO, Wolk A, Bergstrom R et al. (1997) Body size and prostate cancer: a 20-year follow-up study among 135006 Swedish construction workers. J Natl Cancer Inst 89: 385–9

    CAS  PubMed  Google Scholar 

  • Aronson WJ, Barnard RJ, Freedland SJ et al. (2010) Growth inhibitory effect of low fat diet on prostate cancer cells: results of a prospective, randomized dietary intervention trial in men with prostate cancer. J Urol 183 (1): 345–50

    CAS  PubMed Central  PubMed  Google Scholar 

  • Attia S, Eickhoff J, Wilding G et al. (2008) Randomized, double-blinded phase II evaluation of docetaxel with or without doxercalciferol in patients with metastatic, androgen-independent prostate cancer. Clin Cancer Res 14 (8): 2437–43

    CAS  PubMed  Google Scholar 

  • Augustsson K, Michaud DS, Rimm EB et al. (2003) A prospective study of intake of fish and marine fatty acids and prostate cancer. Cancer Epidemiol Biomarkers Prev 12: 64–7

    CAS  PubMed  Google Scholar 

  • Bae et al. (2008) Citrus fruits intake and prostate cancer risk: a quantitative systematic review. J Prev Med Pub Health 41 (3): 159–64

    Google Scholar 

  • Berkow SE, Barnard ND, Saxe GA, Ankerberg-Nobis T (2007) Diet and survival after prostate cancer diagnosis. Nutr Rev 65 (9): 391–403

    PubMed  Google Scholar 

  • Block, G (1991) Vitamin C and cancer prevention: the epidemiologic evidence. Am J Clin Nutr 53 (1 Suppl): 270S–282S

    Google Scholar 

  • Boileau TW, Liao Z, Kim S et al. (2003) Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. J Natl Cancer Inst 95 (21): 1578–86

    CAS  PubMed  Google Scholar 

  • Boon H, Westlake K, Stewart M, Gray R, Fleshner N, Gavin A et al. (2003) Use of complementary/alternative medicine by men diagnosed with prostate cancer: prevalence and characteristics. Urology 62: 849–53

    PubMed  Google Scholar 

  • Borad MJ, Swift R et al. (2005) Efficacy of melphalan, arsenic trioxide, and ascorbic acid combination therapy (MAC) in relapsed and refractory multiple myeloma. Leukemia 19 (1): 154–6

    CAS  PubMed  Google Scholar 

  • Bradbury BD, Wilk JB, Kaye JA (2005) Obesity and the risk of prostate cancer (United States). Cancer Causes Control 16: 637–41

    PubMed  Google Scholar 

  • Brinkman M, Buntinx F, Zeegers MP (2006) Use of selenium in chemoprevention of bladder cancer. Lancet Oncology 7 (9)766–774

    Google Scholar 

  • Brinkman MT, Karagas MR, Zens MS et al. (2011a) Intake of a-linolenic acid and other fatty acids in relation to the risk of bladder cancer. Br J Nutr 10: 1–8

    Google Scholar 

  • Brinkman MT, Buntinx F, Kellen E et al. (2011b) Dietary intake of micronutrients and the risk of developing bladder cancer: results from the Belgian case-control study on bladder cancer risk. Cancer Causes Control 22 (3): 469–78

    Google Scholar 

  • Brinkman MT, Buntinx F, Kellen E et al. (2011c) Consumption of animal products, olive oil and dietary fat and results from the Belgian case-control study on bladder cancer risk. Eur J Cancer 47 (3): 436–42

    CAS  Google Scholar 

  • Brooks JD, Metter, EJ, Chan DW et al. (2001) Plasma Selenium level before diagnosis and the risk of prostate cancer development. J Urol 166: 2034–2038

    CAS  PubMed  Google Scholar 

  • Büchner FL, Bueno-de-Mesquita HB, Ros MM et al. (2011) Variety in vegetable and fruit consumption and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition. Int J Cancer 128 (12): 2971–9

    PubMed  Google Scholar 

  • Caffrey PB, Renkel GD (1992) Selenite cytotoxicity in drug resistant and nonresistant human ovarian tumor cells. Cancer Res 52: 4812–4816

    CAS  PubMed  Google Scholar 

  • Cameron E (1991) Protocol for the use of vitamin C in the treatment of cancer. Med Hypotheses 36 (3): 190–4

    CAS  PubMed  Google Scholar 

  • Cameron E, Pauling l (1978) Experimental studies designed to evaluate the management of patients with incurable cancer. Proc Natl Acad Sci USA 75 (12): 6252

    CAS  PubMed Central  PubMed  Google Scholar 

  • Campbell SE, Rudder B, Phillips RB et al. (2011) γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer. Free Radic Biol Med 50 (10): 1344–54

    CAS  PubMed  Google Scholar 

  • Cathcart RF (1981) Vitamin C, titrating to bowel tolerance, anascorbemia and acute induced scurvy. Medical Hypotheses 7: 1359–76

    CAS  PubMed  Google Scholar 

  • Chan JM, Holick CN, Leitzmann MF et al. (2006) Diet after diagnosis and the risk of prostate cancer progression, recurrence, and death (United States). Cancer Causes Control 17 (2): 199–208

    PubMed  Google Scholar 

  • Chang-Claude J, Frentzel-Beyme R, Eilber U (1992) Mortality pattern of German vegetarians after 11 years follow-up. Epidemiology 3: 395–401

    CAS  PubMed  Google Scholar 

  • Chen TC (2008) 25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate. Anticancer Res 28 (4A): 2015–7

    CAS  PubMed  Google Scholar 

  • Chen TC, Schwartz GG, Holick MF et al. (2000) The in vitro evaluation of 25-hydroxyvitamin D3 and 19-nor-1alpha,25-dihydroxyvitamin D2 as therapeutic agents for prostate cancer. Clin Cancer Res 6 (3): 901–908

    CAS  PubMed  Google Scholar 

  • Chen L, Stacewicz-Sapuntzakis M, Duncan C et al. (2001) Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. J Natl Cancer Inst 93: 1872–1879

    CAS  PubMed  Google Scholar 

  • Chen TC, Wang L, Whitlatch LW et al. (2003) Prostatic 25-hydroxyvitamin D-1alphahydroxylase and its implication in prostate cancer. J Cell Biochem 88: 315–322

    CAS  PubMed  Google Scholar 

  • Chen Q, Espey MG, Levine M et al. (2005) Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissue. Proc Natl Acad Sci USA 102: 13604–9

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chen Q, Espey MG, Levine M et al. (2008) Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Proc Natl Acad Sci USA 105 (32): 11105–9

    CAS  PubMed Central  PubMed  Google Scholar 

  • Choo CS, Mamedov A, Chung M et al. (2011) Vitamin D insufficiency is common in patients with nonmetastatic prostate cancer. Nutr Res 31 (1): 21–26

    CAS  PubMed  Google Scholar 

  • Christen S, Woodall AA, Shigenaga MK et al. (1997) Gamma-tocopherol traps mutagenic electrophiles such as NO (X) and complements alpha-tocopherol: physiological implications. Proc Natl Acad Sci USA 94: 3217–22

    CAS  PubMed Central  PubMed  Google Scholar 

  • Christudoss P, Selvakumar R, Fleming JJ, Gopalakrishnan G (2011) Zinc status of patients with benign prostatic hyperplasia and prostate carcinoma. Indian J Urol 27 (1): 148

    Google Scholar 

  • Clark LC, Combs GF, Turnbull BW et al. (1996) Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group. JAMA 276: 1957

    CAS  PubMed  Google Scholar 

  • Clinton SK, Emenhiser C, Schwartz SJ et al. (1996) Cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers Prev 5 (10): 823–33

    CAS  PubMed  Google Scholar 

  • Colli et al. (2006) International comparisons of prostate cancer mortality rates with dietary practices and sunlight levels. Urol Oncol 24 (3): 184–94

    Google Scholar 

  • Corcoran NM, Najdovska M, Costello AJ (2004) Inorganic selenium retards progression of experimental hormone refractory prostate ancer. J Urol 171: 907–910

    CAS  PubMed  Google Scholar 

  • Costello LC, Franklin RB (1998) Novel role of zinc in the regulation of prostate citrate metabolism and ist implications in prostate cancer. Prostate 35: 285–296

    CAS  PubMed  Google Scholar 

  • Cross AJ, Peters U, Kirsh VA et al. (2005) A prospective study of meat and meat mutagens and prostate cancer risk. Cancer Res 65 (24): 11779–84

    CAS  PubMed  Google Scholar 

  • De Nunzio C, Freedland SJ, Miano R et al. (2011) Metabolic syndrome is associated with high grade gleason score when prostate cancer is diagnosed on biopsy. Prostate (25.02.2011, Epub ahead of print)

    Google Scholar 

  • Dewailly E, Mulvad G, Sloth Pedersen H et al. (2003) Inuit are protected against prostate cancer. Cancer Epidemiol Biomarkers Prev 12: 926–7

    PubMed  Google Scholar 

  • DGE (2000) Referenzwerte für die Nährstoffzufuhr. Umschau/Braus, S. 139

    Google Scholar 

  • Donaldson (2004) Nutrition and cancer: a review of the evidence for an anti-cancer diet. Nutr J 3: 19

    PubMed Central  PubMed  Google Scholar 

  • Dong Y, Lee, SO, Zhang H et al. (2004) Prostate Specific Antigen Expression is Down-Regulated by Selenium through Disruption of Androgen Receptor Signaling. Canc Res 64: 19–22

    CAS  Google Scholar 

  • Druesne-Pecollo N, Latino-Martel P, Norat T et al. (2010) Beta-carotene supplementation and cancer risk: a systematic review and metaanalysis of randomized controlled trials. Int J Cancer 127 (1): 172–84

    CAS  PubMed  Google Scholar 

  • Edinger MS, Koff WJ (2006) Effect of the consumption of tomato paste on plasma prostate-specific antigen levels in patients with benign prostate hyperplasia. Braz J Med Biol Res 39 (8): 1115–9

    CAS  PubMed  Google Scholar 

  • Eichholzer M (2000) Ernährung und Krebs. Ther Umschau 57 (3): 146–151

    CAS  Google Scholar 

  • Epstein MM, Kasperzyk JL, Andrén O, Giovannucci EL et al. (2011) Dietary zinc and prostate cancer survival in a Swedish cohort. Am J Clin Nutr 93 (3): 586–93

    CAS  PubMed Central  PubMed  Google Scholar 

  • Fain O, Mathieu E, Thomas M (1998) Scurvy in patients with cancer. BMJ 316 (7145): 1661–2

    CAS  PubMed Central  PubMed  Google Scholar 

  • Fay MP, Freedman LS, Clifford CK, Midthune DN (1997) Effect of different types and amounts of fat on the development of mammary tumors in rodents: a review. Cancer Res 57: 3979–88

    CAS  PubMed  Google Scholar 

  • Ferrucci LM, Sinha R, Ward MH et al. (2010) Meat and components of meat and the risk of bladder cancer in the NIH-AARP Diet and Health Study. Cancer.116 (18): 4345–53

    PubMed Central  PubMed  Google Scholar 

  • Fleischhauer AT, Arab L (2001) Garlic and cancer: A critical review of the epidemiologic literature. J Nutr 131: 1032–1040

    Google Scholar 

  • Fleshner NE (2002) Vitamin E and prostate cancer. Urol Clin North Am 29: 107–13

    PubMed  Google Scholar 

  • Fleshner NE, Kapusta L, Donnelly B et al. (2011) Progression from high-grade intraepithelial neoplasia to cancer: a randomized trial of combination vitamin-e, soy, and selenium. J Clin Oncol 29 (17): 2386–2390

    CAS  PubMed  Google Scholar 

  • Freedman LS, Clifford C, Messina M (1990) Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review. Cancer Res 50: 5710–9

    CAS  PubMed  Google Scholar 

  • Frömberg A, Gutsch D, Schulze D et al. (2011) Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs. Cancer Chemother Pharmacol 67 (5): 1157–66

    PubMed Central  PubMed  Google Scholar 

  • Fujioka t, Hasegawa M, Ishikura K et al. (1998) Inhibiton of tumor growth and angiogenesis by vitamin D3 agents in murine renal cell carcinoma. J Urol 160: 247–251

    CAS  PubMed  Google Scholar 

  • Galli F, Stabile AM, Betti M et al. (2004) The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation. Arch Biochem Biophys 423 (1): 97–102

    CAS  PubMed  Google Scholar 

  • Gandini S, Boniol M, Haukka J et al. (2011) Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorfectal adenoma. Int J Cancer 128 (6): 1414–1424

    CAS  PubMed  Google Scholar 

  • Gao X, LaValley MP, Tucker KL (2005) Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis. J Natl Cancer Inst 97 (23): 1768–77

    CAS  PubMed  Google Scholar 

  • Garland M, Morris JS, Stampfer MJ et al. (1995) Prospective study of toenail selenium levels and cancer among women. J Natl Cancer Inst 87: 497–505

    CAS  PubMed  Google Scholar 

  • Gaziano JM, Glynn RJ, Christen WG et al. (2009) Vitamins E and C in the prevention of prostate and total cancer in men. JAMA 301: 52–62

    CAS  PubMed Central  PubMed  Google Scholar 

  • Gianduzzo TR, Holmes EG, Tinggi U et al. (2003) Prostatic and peripheral blood selenium levels after oral supplementation. J Urol 170: 870–873

    CAS  PubMed  Google Scholar 

  • Gilbert R, Martin RM, Beynon R et al. (2011) Associations of circulating and dietary vitamin D with prostate cancer risk: a systematic review and dose-response meta-analysis. Cancer Causes Control 223): 319–40

    Google Scholar 

  • Giovannucci E (1999) Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature. J Natl Cancer Inst 91 (4): 317–31

    CAS  PubMed  Google Scholar 

  • Giovannucci E (2005) The epidemiology of vitamin D and cancer incidence and mortality: A review (United States). Cancer Causes Control 16 (2): 83–95

    PubMed  Google Scholar 

  • Giovannucci E, Rimm EB, Liu Y et al. (2003) A prospective study of cruciferous vegetables and prostate cancer. Cancer Epidemiol Biomarkers Prev 12 (12): 1403–1409

    CAS  PubMed  Google Scholar 

  • Gonzalez CA (2006) The European Prospective Investigation into Cancer and Nutrition (EPIC). Public Health Nutr 9 (1A): 124–6

    PubMed  Google Scholar 

  • Goodman GE, Schaffer S, Omenn GS et al. (2003) The association between lung and prostate cancer risk, and serum micronutrients. Results and Lessons Learned from ß-Carotene and Retinol Efficacy Trial. Cancer Epidemio Biomarkers Prev 12 (6): 518–526

    CAS  Google Scholar 

  • Gosh J (2004) Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase. Biochem Biophy Res Com 315: 624–635

    Google Scholar 

  • Grainger EM, Schwartz SJ, Wang S et al. (2008) A combination of tomato and soy products for men with recurring prostate cancer and rising prostate specific antigen. Nutr Cancer 60 (2): 145–54

    CAS  PubMed  Google Scholar 

  • Grant WB (2002) An estimate of premature cancer mortality in the US due to inadequate radiation of solar ultraviolet-B radiation. Cancer 94: 1867–1875

    PubMed  Google Scholar 

  • Hanchette CL, Schwartz GG (1992) Geographic patterns of prostate cancer mortality. Cancer 70: 2861–2869

    CAS  PubMed  Google Scholar 

  • Haseen F, Cantwell MM, O’Sullivan JM, Murray LJ (2009) Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic Dis 12 (4): 325–332

    CAS  PubMed  Google Scholar 

  • Heaney ML, Gardner JR, Karasavvas N et al. (2008) Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs. Cancer Res 68: 8031–8038

    CAS  PubMed Central  PubMed  Google Scholar 

  • Heinonen OP, Albanes D, Virtamo J et al. (1998) Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. J Natl Cancer Inst 90: 440–446

    CAS  PubMed  Google Scholar 

  • Hennekens CH, Buring JE, Manson JE et al. (1996) Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 334 (18): 1145–1149

    CAS  PubMed  Google Scholar 

  • Hercberg S, Galan P, Preziosi P et al. (2004) The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidnt vitamins and minerals. Arch Intern Med 164: 2335–2342

    CAS  PubMed  Google Scholar 

  • Hershberger PA, Yu WD, Medzelewski RA et al. (2001) Calcitriol (1,25-dihydroxycholecalciferol) enhances paclitaxel antitumor activity in vitro and in vivo and accerlaters paclitaxel-induced apoptosis. Clin Cancer Res 7: 1043–1051

    CAS  PubMed  Google Scholar 

  • Hirayama T (1985) A large scale cohort study on cancer risks by diet – with special reference to the risk reducing effects of green-yellow vegetable consumption. Princess Takamatsu Symp 116: 41–53

    Google Scholar 

  • Hoffer LJ, Levine M, Assouline S, Miller WH et al. (2008) Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Ann Oncol 19 (11): 1969–74

    CAS  PubMed  Google Scholar 

  • Holick CN, De Vivo I, Giovannucci E et al. (2005) Intake of fruits and vegetables, carotenoids, folate, and vitamins A, C, E and risk of bladder cancer among women (United States). Cancer Causes Control 16 (10): 1135–45

    PubMed  Google Scholar 

  • Holick CN, Giovannucci EL, Stampfer MJ, Michaud DS (2007) Prospective study of body mass index, height, physical activity and incidence of bladder cancer in US men and women. Int J Cancer 120 (1): 140–6

    CAS  PubMed  Google Scholar 

  • Hotaling JM, Wright JL, Pocobelli G et al. (2011) Long-term use of supplemental vitamins and minerals does not reduce the risk of urothelial cell carcinoma of the bladder in the VITamins And Lifestyle study. J Urol 185 (4): 1210–5

    CAS  PubMed Central  PubMed  Google Scholar 

  • Hu J, Straub J, Xiao D et al. (2007) Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. Cancer Res 67 (8): 3569–3573

    CAS  PubMed  Google Scholar 

  • Hwang YW, Kim SY, Jee SH et al. (2009) Soy food consumption and risk of prostate cancer: a meta-analysis of observational studies. Nutr Cancer 61 (5): 598–606

    CAS  PubMed  Google Scholar 

  • Iso H, Kubota Y (2007) Nutrition and disease in the Japan Collaborative Cohort Study for Evaluation of Cancer (JACC). Asian Pac J Cancer Prev 8 Suppl: 35–80

    Google Scholar 

  • ISRCTN [http://www.controlled-trials.com/ISRCTN13889738] (Stand 19.07.2011)

  • Itsiopoulos C, Hodge A, Kaimakamis M (2008) Can the Mediterranean diet prevent prostate cancer? Mol Nutr Food Res [Epub ahead of print]

    Google Scholar 

  • Jamison JM, Gilloteaux J, Taper HS et al. (2001) Evaluation of the in vitro and in vivo antitumor activities of vitamin C and K-3 combinations against human prostate cancer. J Nutr 131 (1): 158S–160S

    CAS  PubMed  Google Scholar 

  • Jian L, Xie LP, Lee AH, Binns CW (2004) Protective effect of green tea against prostate cancer: a case-control study in southeast China Int J Cancer 108 (1): 130–5

    Google Scholar 

  • Jiang L, Yang KH, Tian JH et al. (2010) Efficacy of antioxidant vitamins and selenium supplement in prostate cancer prevention: a meta-analysis of randomized controlled trials. Nutr Cancer 62 (6): 719–27

    CAS  PubMed  Google Scholar 

  • John EM, Stern MC, Sinha R, Koo J (2011) Meat consumption, cooking practices, meat mutagens, and risk of prostate cancer. Nutr Cancer 63 (4): 525–37

    PubMed Central  PubMed  Google Scholar 

  • Karlsson S, Olausson J, Lundh D et al. (2010) Vitamin D and prostate cancer: the role of membrane initiated signalling pathways in prostate cancer progression. J Steroid Biochem Mol Biol 121 (1–2): 413–416

    CAS  PubMed  Google Scholar 

  • Kassouf W, Highshaw R, Nelkin GM et al. (2006) K3 sensitize human urothelial tumors to gemcitabine. J Urol 176: 1642–1647

    CAS  PubMed  Google Scholar 

  • Kellen E, Zeegers M, Paulussen A et al. (2006) Fruit consumption reduces the effect of smoking on bladder cancer risk. The Belgian case control study on bladder cancer. Int J Cancer 118 (10): 2572–8

    CAS  PubMed  Google Scholar 

  • Kennedy DD, Tucker KL et al. (2004) Low antioxidant vitamin intakes are associated with increases in adverse effects of chemotherapy in children with acute lymphoblastic leukemia. Am J Clin Nutr 79: 1029–36

    CAS  PubMed  Google Scholar 

  • Kesse E, Bertrais S, Hercberg S et al. (2006) Dairy products, calcium and phosphorus intake, and the risk of prostate cancer: results of the French prospective SU.VI.MAX (Supplémentation en Vitamines et Minéraux Antioxydants) study. Br J Nutr 95 (3): 539–45

    CAS  PubMed  Google Scholar 

  • Keszei AP, Schouten LJ, Goldbohm RA, van den Brandt PA (2010) Dairy intake and the risk of bladder cancer in the Netherlands Cohort Study on Diet and Cancer. Am J Epidemiol 171 (4): 436–46

    PubMed  Google Scholar 

  • Key TJ, Appleby PN, Allen NE, Riboli E et al. (2007) Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. Am J Clin Nutr 86 (3): 672–81

    CAS  PubMed  Google Scholar 

  • Key TJ, Appleby PN, Spencer EA et al. (2009) Cancer incidence in British vegetarians. Br J Cancer 101 (1): 192–7

    CAS  PubMed Central  PubMed  Google Scholar 

  • Khaw K, Bingham S, Luben R et al. (2001) Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. Euroean Prospective Investigation into Cancer and Nutrition. Lancet 357 (9257): 657–663

    CAS  PubMed  Google Scholar 

  • Kim DJ, Gallagher RP, Hislop TG et al. (2000) Premorbid diet in relation to survival from prostate cancer (Canada). Cancer Causes Control 11: 65–77

    CAS  PubMed  Google Scholar 

  • Kirsh VA, Hayes RB, Mayne ST et al. (2006) Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk. J Natl Cancer Inst 98 (4): 245–54

    CAS  PubMed  Google Scholar 

  • Klein EA, Thompson IM Jr, Tangen CM et al. (2011) Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 306 (14): 1549–56

    CAS  PubMed  Google Scholar 

  • Klein E, Lippman S, Thompson I et al. (2003) The Selenium an Vitamin E Cancer Prevention Trial. World J Urol 21: 21–27

    CAS  PubMed  Google Scholar 

  • Koerber K, Männle T, Leitzmann C (2004) Vollwert-Ernährung, 10. Aufl. Haug-Verlag, Stuttgart

    Google Scholar 

  • Kokron O, Alth G, Cerni C et al. (1982) Ergebnisse einer vergleichenden Therapiestudie beim inoperablen Bronchuskarzinom. Onkologie 5: 20–22

    CAS  PubMed  Google Scholar 

  • Kolonel LN (2001) Fat, meat and prostate cancer. Epidemiol Rev 23: 72–81

    CAS  PubMed  Google Scholar 

  • Kopp RP, Han M, Partin AW et al. (2011) Obesity and prostate enlargement in men with localized prostate cancer. BJU Int (08.07.2011, Epub ahead of print)

    Google Scholar 

  • Koutros S, Cross AJ, Sandler DP et al. (2008) Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study. Cancer Epidemiol Biomarkers Prev 17 (1): 80–7

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kranse R, Dagnelie PC, Schröder FH et al. (2005) Dietary intervention in prostate cancer patients: PSA response in a randomized double-blind placebo-controlled study. Int J Cancer 113 (5): 835–40

    CAS  PubMed  Google Scholar 

  • Kristal AR, Till C, Platz EA et al. (2011) Serum lycopene concentration and prostate cancer risk: results from the Prostate Cancer Prevention Trial. Cancer Epidem Biomarkers Prev 20 (4): 638–646

    CAS  Google Scholar 

  • Kucuk O, Sarkar F, Sakr W et al. (2001) Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. Cancer Epidemiol Biomarkers Prev 10: 861–868

    CAS  PubMed  Google Scholar 

  • Kumar NB, Besterman-Dahan K, Kang L et al. (2008) Results of a randomized clinical trial of the action of several doses of lycopene in localized prostate cancer: administration prior to radical prostatectomy. Clin Med Urol 1: 1–14

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kurahashi et al. (2008) Green tea consumption and prostate cancer risk in Japanese men: a prospective study. Am J Epidemiol 167 (1): 71–7

    Google Scholar 

  • Kurbacher CM, Wagner U et al. (1996) Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro. Cancer Lett 103 (2): 183–9

    CAS  PubMed  Google Scholar 

  • Lawson KA, Wright ME, Leitzmann MF et al. (2007) Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study. J Natl Cancer Inst 99 (10): 754–64

    CAS  PubMed  Google Scholar 

  • Leitzmann C (1995) Ernährung und Krebs. In: Wrba (Hrsg) Kombinierte Tumortherapie. Hippokrates, Stuttgart

    Google Scholar 

  • Leitzmann C, Müller C, Michel P et al. (2003) Ernährung in Prävention und Therapie, 2. Auflage. Hippokrates, Stuttgart

    Google Scholar 

  • Leitzmann MF, Stampfer MJ, Wu K et al. (2003) Zinc supplement use and risk of prostate cancer. J Natl Cancer Inst 95: 1004–7

    CAS  PubMed  Google Scholar 

  • Levine M, Rumsey SC et al. (1999) Criteria and recommendations for vitamin C intake. JAMA 281 (15): 1415–23

    CAS  PubMed  Google Scholar 

  • Levy J, Bosin D, Feldman B et al. (1995) Lycopene is a more potent inhibitor of human cancer cell proliferation than either alpha-carotene or beta-carotene. Nutr Cancer 24 (3): 257–66

    CAS  PubMed  Google Scholar 

  • Liang D, Lin J, Grossman HB et al. (2008) Plasma vitamins E and A and risk of bladder cancer: a case-control analysis. Cancer Causes Control 19 (9): 981–92

    PubMed  Google Scholar 

  • Lippman SM, Klein EA, Goodman PJ et al. (2009) Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 301 (1): 39–51

    CAS  PubMed Central  PubMed  Google Scholar 

  • Liu G, Wilding G, Staab MJ et al. (2003). Phase II study of 1alpha-hydroxyvitamin D (2) in the treatment of advanced androgen-independent prostate cancer. Clin Cancer Res 9 (11): 4077–83

    CAS  PubMed  Google Scholar 

  • Llaverias G, Danilo C, Wang Y et al. (2010) A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer. Am J Pathol 177 (6): 3180–91

    CAS  PubMed Central  PubMed  Google Scholar 

  • Lokeshwar BL, Schwartz GG, Selzer MG et al. (1999) Inhibition of prostate cancer metastasis in vivo: a comparison of 1,25-dihydroxyvitamin D (calcitriol) and EB 1089. Cancer Epidemiol Biomark Prev 8: 241–248

    CAS  Google Scholar 

  • Ma Y, Yu WD, Trump DL, Johnson CS (2010) 1,25D3 enhances antitumor activity of gemcitabine and cisplatin in human bladder cancer models. Cancer 116 (13): 3294–3303

    CAS  PubMed Central  PubMed  Google Scholar 

  • Mayland CR, Bennett MI, Allan K (2005) Vitamin C deficiency in cancer patients. Palliat Med 19 (1): 17–20

    PubMed  Google Scholar 

  • Mazdak H, Yazdekhasti F, Movahedian A et al. (2010) The comparative study of serum iron, copper, and zinc levels between bladder cancer patients and a control group. Int Urol Nephrol 42 (1): 89–93

    CAS  PubMed  Google Scholar 

  • Meyer F, Galan P, Hercberg S et al. (2005) Antioxidant vitamin and mineral supplementation and prostate cancer prevention in the SU.VI.MAX trial. Int J Cancer 116 (2): 182–6

    CAS  PubMed  Google Scholar 

  • Meyer F. Bairati I, Shadmani R et al. (1999) Dietary fat and prostate cancer survival. Cancer Causes Control 10: 245–251

    PubMed  Google Scholar 

  • Michaud DS, Spiegelman D, Giovannucci E et al. (2000) Prospective study of dietary supplements, macronutrients, micronutrients, and risk of bladder cancer in US men. Am J Epidemiol 152: 1145–53

    CAS  PubMed  Google Scholar 

  • Michaud DS, Spiegelman D, Giovannucci EL et al. (1999) Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst 91 (7): 605–13

    CAS  PubMed  Google Scholar 

  • Michaud DS, Virtamo J, Albanes D et al. (2002) Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study. Br J Cancer 87 (9): 960–5

    CAS  PubMed Central  PubMed  Google Scholar 

  • Miller ER, Pastor-Barriuso R, Dalal D et al. (2005) Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 142: 37–46

    CAS  PubMed  Google Scholar 

  • Moertel C, Fleming T et al. (1985) High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison. N Engl J Med 312 (3): 137–141

    CAS  PubMed  Google Scholar 

  • Mondul AM, Weinstein SJ, Männistö S et al. (2010) Serum vitamin D and risk of bladder cancer. Cancer Res 70 (22): 9218–23

    CAS  PubMed Central  PubMed  Google Scholar 

  • Mondul AM, Watters JL, Männistö S et al. (2011) Serum retinol and risk of prostate cancer. Am J Epidemiol 173 (7): 813–21

    PubMed Central  PubMed  Google Scholar 

  • Moyad, M (2003) The use of complementary/preventive medicine to prevent prostate cancer recurrence/progression following definitive therapy: Part I. Lifestyle changes. Curr Opin Urol 13 (2): 137–145

    PubMed  Google Scholar 

  • Mühlhöfer A, Mrosek S, Biesalski HK et al. (2004) High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers. Eur J Clin Nutr 58 (8): 1151–8

    PubMed  Google Scholar 

  • Nelson PS, Montgomery B (2003) Unconventional therapy for prostate cancer: Good, Bad or questionable? Nature Rev 3: 845–858

    CAS  Google Scholar 

  • Nesby-O`Dell S, Scanlon KS, Cogswell ME et al. (2002) Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988–1994. Am J Clin Nutr 76: 187–192

    CAS  Google Scholar 

  • Newmark HL, Heaney RP (2010) Dairy products and prostate cancer risk. Nutr Cancer 62 (3): 297–9.

    CAS  PubMed  Google Scholar 

  • Nguyen JY, Major JM, Saxe GA et al. (2006) Adoption of a plant-based diet by patients with recurrent prostate cancer. Integr Cancer Ther 5 (3): 214–23

    CAS  PubMed  Google Scholar 

  • Omenn GS, Goodman GE, Thromquist MD et al. (1996) Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst 88 (21): 1550–1559

    CAS  PubMed  Google Scholar 

  • Park SY, Murphy SP, Kolonel, LN et al. (2007) Fat and meat intake and prostate cancer risk: The Multiethnic Cohort Study. Int. J. Cancer 121: 1339–1345

    CAS  PubMed  Google Scholar 

  • Park SY, Murphy SP, Kolonel LN et al. (2008) Legume and isoflavone intake and prostate cancer risk: The Multiethnic Cohort Study. Int. J. Cancer 123: 927–932

    CAS  PubMed Central  PubMed  Google Scholar 

  • Park SY, Cooney RV, Wilkens LR et al. (2010) Plasma 25-hydroxyvitamin D and prostate cancer risk: the multiethnic cohort. Eur J Cancer 46 (5): 932–936

    CAS  PubMed Central  PubMed  Google Scholar 

  • Pascoe (2008) Die Vitamin C Hochdosis-Infusions-Therapie. Wissenschaftliche Broschüre. Firma Pascoe, Giessen, 3. Aufl.

    Google Scholar 

  • Pelucchi C, La Vecchia C (2009) Alcohol, coffee, and bladder cancer risk: a review of epidemiologic studies. Eur J Cancer Prev 18 (1): 62–68

    PubMed  Google Scholar 

  • Peters U, Foster CB, Chatterjee N et al. (2007) Serum selenium and risk of prostate cancer – a nested case-control study. Am J Clin Nutr 85 (1): 209–17

    CAS  PubMed Central  PubMed  Google Scholar 

  • Peters U, Littman AJ, Kristal AR et al. (2008) Vitamin E and selenium supplementation and risk of prostate cancer in the Vitamins and lifestyle (VITAL) study cohort. Cancer Causes Control 19 (1): 75–87

    PubMed  Google Scholar 

  • Prasad KN, Sinha PK et al. (1979) Sodium ascorbate potentiates the growth inhibitory effect of certain agents on neuroblastoma cells in culture. Proc Natl Acad Sci USA 76 (2): 829–32

    CAS  PubMed Central  PubMed  Google Scholar 

  • Prasad AS, Mukhtar H, Beck FW et al. (2010) Dietary zinc and prostate cancer in the TRAMP mouse model. J Med Food 13 (1): 70–6

    CAS  PubMed Central  PubMed  Google Scholar 

  • Raimondi S, Mabrouk JB, Shatenstein B, Maisonneuve P, Ghadirian P (2010) Diet and prostate cancer risk with specific focus on dairy products and dietary calcium: a case-control study. Prostate 70 (10): 1054–65

    CAS  PubMed  Google Scholar 

  • Riordan HD, Casciari JJ, González MJ et al. (2005) A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients. P R Health Sci J 24 (4): 269–76

    PubMed  Google Scholar 

  • Riordan NH, Riordan HD, Meng X et al. (1995) Intravenous ascorbate as a tumor cytotoxic chemotherapeutic agent. Med Hypotheses 44 (3): 207–13

    CAS  PubMed  Google Scholar 

  • Ritch CR, Wan RL, Stephens LB et al. (2007) Dietary fatty acids correlate with prostate cancer biopsy grade and volume in Jamaican men. J Urol 177 (1): 97–101

    CAS  PubMed  Google Scholar 

  • Rodriguez C, McCullough ML, Calle EE et al. (2006) Meat consumption among Black and White men and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort. Cancer Epidemiol Biomarkers Prev 15 (2): 211–6

    PubMed  Google Scholar 

  • Rohrmann S, Platz EA, Helzlsouer KJ et al. (2007) Meat and dairy consumption and subsequent risk of prostate cancer in a US cohort study. Cancer Causes Control 18 (1): 41–50

    PubMed  Google Scholar 

  • Roswall N, Olsen A, Christensen J et al. (2009) Micronutrient intake and risk of urothelial carcinoma in a prospective Danish cohort. Eur Urol 56 (5): 764–70

    CAS  PubMed  Google Scholar 

  • Sabichi AL, Lee JJ, Taylor RJ et al. (2006) Selenium accumulation in prostate tissue during a randomized, controlled short-term trial of l-selenomethionine: a Southwest Oncology Group Study. Clin Cancer Res 12(7 Pt 1): 2178–84

    CAS  PubMed  Google Scholar 

  • Sarafanov AG, Todorov TI, Centeno JA et al. (2011) Prostate cancer outcome and tissue levels of metal ions. Prostate 71 (11): 1231–8

    CAS  PubMed  Google Scholar 

  • Saxe G, Hebert J, Carmody J, Kabat-Zinn J et al. (2001) Can diet, in conjunction with stress reduction, affect the rate of increase in prostate-specific antigen after biochemical recurrence of prostate cancer? J. Urology 66: 2202–2207

    Google Scholar 

  • Scheef W (1995) In: Wrba (Hrsg.) Kombinierte Tumortherapie, Hippokrates Verlag, Stuttgart

    Google Scholar 

  • Schenk JM, Riboli E, Chatterjee N et al. (2009) Serum retinol and prostate cancer risk: a nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 18 (4): 1227–31

    CAS  PubMed Central  PubMed  Google Scholar 

  • Schmid HP, Fischer C, Engeler DS, Bendhack ML, Schmitz-Dräger BJ (2011) Nutritional aspects of primary prostate cancer prevention. Recent Results Cancer Res 188: 101–107

    CAS  PubMed  Google Scholar 

  • Schröder FH, Roobol MJ, Boevé ER et al. (2005) Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement. Eur Urol 48 (6): 922–30

    PubMed  Google Scholar 

  • Schumacher K (2000) Therapie maligner Tumoren. Schattauer, Stuttgart

    Google Scholar 

  • Schwartz GG, Hulka BS (1990) Is vitamin D deficiency a risk factor for prostate cancer? Anticancer Res 10: 1307–1312

    CAS  PubMed  Google Scholar 

  • Schwartz GG, Wang MH, Zhang M et al. (1997) 1α,25-Dihydroxyvitamin D (calcitriol) inhibits the invasiveness of human prostate cancer cells. Cancer Epidemiol. Biomark. Prev 6: 727–732

    CAS  Google Scholar 

  • Schwarz S, Obermüller-Jevic UC, Hellmis E et al. (2008) Lycopene inhibits disease progression in patients with benign prostate hyperplasia. J Nutr 138 (1): 49–53

    CAS  PubMed  Google Scholar 

  • Schwenke C, Ubrig B, Thürmann P et al. (2009) Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J Urol 181 (3) 1098–1103

    CAS  PubMed  Google Scholar 

  • Silberstein JL, Parsons JK (2010) Evidence-based principles of bladder cancer and diet. Urology 75 (2): 340–6

    PubMed  Google Scholar 

  • Spaccarotella KJ, Kris-Etherton PM, Stone WL et al. (2008) The effect of walnut intake on factors related to prostate and vascular health in older men. Nutr J 7: 13

    PubMed Central  PubMed  Google Scholar 

  • Stamatiou K, Delakas D, Sofras F (2007) Mediterranean diet, monounsaturated: saturated fat ratio and low prostate cancer risk. A myth or a reality? Minerva Urologica e Nefrologica 59 (1) 59–66

    CAS  PubMed  Google Scholar 

  • Steinmaus CM, Nunez S, Smith AH (2000) Diet and bladder cancer: a meta-analysis of six dietary variables. Am J Epidemiol 151: 693–702

    CAS  PubMed  Google Scholar 

  • Su LJ, Arab L, Steck SE et al. (2011) Cancer Epidemiol Biomarkers Prev 20 (5): 844–53

    PubMed  Google Scholar 

  • Szymanski KM, Wheeler DC, Mucci LA (2010) Fish consumption and prostate cancer risk: a review and meta-analysis. Am J Clin Nutr 92 (5): 1223–1233

    CAS  PubMed  Google Scholar 

  • Tang Y, Parmakhtiar B, Simoneau AR et al. (2011) Lycopene enhances docetaxel’s effect in castration-resistent prostate cancer associated with insulin-like growth factor I receptor levels. Neoplasia 13 (2): 108–119

    CAS  PubMed Central  PubMed  Google Scholar 

  • Taper HS, Jamison JM, Gilloteaux J et al. (2004) Inhibition of the development of metastases by dietary vitamin C: K3 combination. Life Sci 75: 955–967

    CAS  PubMed  Google Scholar 

  • Tarumoto T, Nagai T et al. (2004) Ascorbic acid restores sensitivity to imatinib via suppression of Nrf2–dependent gene expression in the imatinib-resistant cell line. Exp Hematol 32 (4): 375–81

    CAS  PubMed  Google Scholar 

  • Terry P, Lichtenstein P, Feychting M et al. (2001) Fatty fish consumption and risk of prostate cancer. Lancet 357: 1764–6

    CAS  PubMed  Google Scholar 

  • The α-Tocopheraol β-Carotene Cancer Prevention Study Group (1994) The effect of vitamin E and β-Carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330: 1029–1035

    Google Scholar 

  • Tripathi A, Folsom AR, Anderson KE (2002) Risk factors for urinary bladder carcinoma in postmenopausal women. The Iowa Women’s Health Study. Cancer 95 (11): 2316–23

    PubMed  Google Scholar 

  • Tseng M, Breslow RA, Graubard BI, Ziegler RG (2005) Dairy, calcium, and vitamin D intakes and prostate cancer risk in the National Health and Nutrition Examination Epidemiologic Follow-up Study cohort. Am J Clin Nutr 81 (5): 1147–54

    CAS  PubMed  Google Scholar 

  • Uzzo RG, Leavis P, Hatch W et al. (2002) Zinc inhibits nuclear factor-kappa B activation and sensitizes prostate cancer cells to cytotoxic agents. Clin Cancer Res 8: 3579–83

    CAS  PubMed  Google Scholar 

  • Vaishampayan U, Hussain M, Banerjee M, Kucuk O et al. (2007) Lycopene and soy isoflavones in the treatment of prostate cancer. Nutr Cancer 59 (1): 1–7

    CAS  PubMed  Google Scholar 

  • Venkateswaran V, Fleshner NE, Klotz LH (2002) Modulation of cell proliferation and cell cycle regulators by vitamin E in human prostate carcinoma cell lines. J Urol 168: 1578–82

    CAS  PubMed  Google Scholar 

  • Virtamo J, Pientinen P, Huttunen JK et al. (2003) ATBC Study Group. Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up. JAMA 290: 476–485

    CAS  PubMed  Google Scholar 

  • Wakai K, Takashi M, Okamura K et al. (2002) Foods and nutrients in relation to bladder cancer risk: a case-control study in Aichi Prefecture, Central Japan. Nutr Cancer 38: 13–22

    Google Scholar 

  • Wallström P, Bjartell A, Gullberg B, Olsson H, Wirfält E (2007) A prospective study on dietary fat and incidence of prostate cancer (Malmö, Sweden). Cancer Causes Control 18 (10): 1107–21

    PubMed  Google Scholar 

  • Watters JL, Gail MH, Weinstein SJ et al. (2009) Associations between alpha-tocopherol, beta-carotene, and retinol and prostate cancer survival. Cancer Res 69 (9): 3833–41

    CAS  PubMed Central  PubMed  Google Scholar 

  • WeillP, Schmitt B, Chesneau G, Daniel N, Safraou F, Legrand P (2002) Effects of introducing linseed in livestock diet on blood fatty acid composition of consumers of animal products. Annals of Nutrition and Metabolism 46 (5): 182–191

    Google Scholar 

  • Weinstein SJ, Wright ME, Albanes D et al. (2007) Serum and dietary vitamin E in relation to prostate cancer risk. Cancer Epidemiol Biomarkers Prev 16 (6): 1253–9

    CAS  PubMed  Google Scholar 

  • Welsh JL et al. (2013) Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial. Cancer Chemother Pharmacol 71 (3): 765–775

    CAS  PubMed Central  PubMed  Google Scholar 

  • West DW, Slattery ML, Robison LM et al. (1991) Adult dietary intake and prostate cancer risk in Utah: a case-control study with special emphasis on aggressive tumors. Cancer Causes Control 2 (2): 85–94

    CAS  PubMed  Google Scholar 

  • Willett WC, Polk BF, Morris JS et al. (1983) Prediagnostic serum selenium and risk of cancer. Lancet 2 (8243): 130–134

    CAS  PubMed  Google Scholar 

  • Williams CD, Whitley BM, Hoyo C et al. (2011) A high ratio of dietary n-6/n-3 polyunsaterated fatty acids is associated with increased risk of prostate cancer. Nutr Res 31 (1): 1–8

    CAS  PubMed  Google Scholar 

  • Wirth M, Hakenberg O (2005) Prävention des Prostatakarzinoms. Dtsch Med Wochenschr 130 (36): 2002–2004

    CAS  PubMed  Google Scholar 

  • Woo TC, Choo R, Jamieson M et al. (2005) Pilot Study: Potential Role of Vitamin D (Cholecalciferol) in Patients With PSA Relapse After Definitive Therapy. Nutrition Cancer 51 (1): 32–36

    CAS  PubMed  Google Scholar 

  • Wright JL, Neuhouser ML, Lin DW et al (2011) AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer risk. Prostate 71 (5): 498–506

    CAS  PubMed Central  PubMed  Google Scholar 

  • Wright ME, Chang SC, Leitzmann MF et al. (2007) Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortality. Cancer 109 (4): 675–84

    PubMed  Google Scholar 

  • Wright ME, Weinstein SJ, Leitzmann MF et al. (2007) Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study. Cancer Epidemiol Biomarkers Prev 16 (6): 1128–35

    CAS  PubMed  Google Scholar 

  • Xiao D, Singh SV (2007) Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo. Cancer Res 67 (5): 2239–2246

    CAS  PubMed  Google Scholar 

  • Yoshizawa K, Willett WC, Morris SJ et al. (1998) Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. J Natl Cancer Inst 90: 1219–1224

    CAS  PubMed  Google Scholar 

  • Yu H, Harris RE, Gao YT et al. (1991) Comparative epidemiology of cancers of the colon, rectum, prostate and breast in Shanghai, China versus the United States. Int J Epidemiol 20: 76–81

    CAS  PubMed  Google Scholar 

  • Zeegers MP, Goldbohm RA, Bode P et al. (2002) Prediagnostic toenail selenium and risk of bladder cancer. Cancer Epidemiol Biomarkers Prev 11: 1292–1297

    CAS  PubMed  Google Scholar 

  • Zeegers MPA, Kellen E, Buntinx F, van den Brandt PA (2004) The association between smoking, beverage consumption, diet and bladder cancer: a systematic literature review. World J Urol 21: 392–401

    PubMed  Google Scholar 

  • Zhang Y, Ni J, Messing E et al. (2002) Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells. PNAS 11: 7408–7413

    Google Scholar 

  • Zheng Y, Zhou H, Ooi LL et al. (2011) Vitamin D deficiency promotes prostate cancer growth in bone. Prostate 71 (9): 1012–1021

    CAS  PubMed  Google Scholar 

Literatur zu ▶ Abschn. 16.3

  • Atlantis E, Chow CM, Kirby A, Singh MF (2004) An effective exercise-based intervention for improving mental health and quality of life measures: a randomized controlled trial. Prev Med 39 (2): 424–34

    PubMed  Google Scholar 

  • Baumann FT, Schüle K (2008) Bewegungstherapie und Sport bei Krebs. Deutscher Ärzte-Verlag, Köln

    Google Scholar 

  • Benson H (1976) The relaxation response. Avon Books, New York

    Google Scholar 

  • Campbell LC, Keefe FJ, Scipio C et al. (2007) Facilitating research participation and improving quality of life for African American prostate cancer survivors and their intimate partners. A pilot study of telephone-based coping skills training. Cancer 109 (2 Suppl): 414–24

    PubMed  Google Scholar 

  • Carmody J, Olendzki B, Reed G et al. (2008) A Dietary Intervention for Recurrent Prostate Cancer After Definitive Primary Treatment: Results of a Randomized Pilot Trial. Urology [Epub ahead of print, April 2008]

    Google Scholar 

  • Chambers SK, Pinnock C, Lepore SJ et al. (2011) A systematic review of psychosocial interventions for men with prostate cancer and their partners. Patient Educ Couns 2011 Feb 17 [Epub ahead of print]

    Google Scholar 

  • Chambers SK, Foley E, Galt E, Ferguson M, Clutton S (2011) Mindfulness groups for men with advanced prostate cancer: a pilot study to assess feasibility and effectiveness and the role of peer support. Support Care Cancer 2011 May 28. [Epub ahead of print]

    Google Scholar 

  • Cohen L, Parker PA, Vence L et al. (2011) Presurgical stress management improves postoperative immune function in men with prostate cancer undergoing radical prostatectomy. Psychosom Med 73 (3): 218–25

    PubMed  Google Scholar 

  • Conn VS, Hafdahl AR, Porock DC et al. (2006) A meta-analysis of exercise interventions among people treated for cancer. Support Care Cancer

    Google Scholar 

  • Daubenmier JJ, Weidner G, Ornish D et al. (2006) Lifestyle and health-related quality of life of men with prostate cancer managed with active surveillance. Urology 67 (1): 125–30

    PubMed  Google Scholar 

  • Davidson RJ, Kabat-Zinn J, Schumacher J et al. (2003) Alterations in brain and immune function produced by mindfulness meditation. Psychosom Med 65 (4): 564–70

    PubMed  Google Scholar 

  • Demark-Wahnefried W, Clipp EC, Cohen HJ et al. (2006) Lifestyle intervention development study to improve physical function in older adults with cancer: outcomes from project LEAD. J Clin Oncol 24 (21): 3465–3473

    PubMed Central  PubMed  Google Scholar 

  • Dobos G, Altner N, Lange S, Michalsen A, Musial F, Paul A (2006) Mind/Body Medicine als Bestandteil der Integrativen Medizin. Bundesgesundheitsblatt

    Google Scholar 

  • Dusek JA, Chang BH, Benson H et al. (2005) Association between oxygen consumption and nitric oxide production during the relaxation response. Med Sci Monit 12 (1): CR1–10

    Google Scholar 

  • Foley E, Baillie A, Huxter M, Price M, Sinclair E (2010) Mindfulness-based cognitive therapy for individuals whose lives have been affected by cancer: a randomized controlled trial. J Consult Clin Psychol 78 (1): 72–9

    PubMed  Google Scholar 

  • Frattaroli J, Weidner G, Ornish D et al. (2008) Clinical Events in prostate cancer lifestyle trial: results from two years of follow-up. Urology [Epub ahead of print]

    Google Scholar 

  • Galvão DA, Nosaka K, Taaffe DR et al. (2006) Resistance training and reduction of treatment side effects in prostate cancer patients. Med Sci Sports Exerc 38 (12): 2045–52

    PubMed  Google Scholar 

  • Giovannucci EL, Lin, Y, Leitzmann MF et al. (2005) A prospective study of physical activity and incident and fatal prostate cancer. Arch Intern Med 165 (9): 1005–1010

    PubMed  Google Scholar 

  • Hoffman JW, Benson H, Arns PA et al. (1982) Reduced sympathetic nervous system responsivity associated with the relaxation response. Science 215 (4529): 190–2

    CAS  PubMed  Google Scholar 

  • Holick CN, Giovannucci EL, Stampfer MJ, Michaud DS (2007) Prospective study of body mass index, height, physical activity and incidence of bladder cancer in US men and women. Int J Cancer 120 (1): 140–6

    CAS  PubMed  Google Scholar 

  • Ibfelt E, Rottmann N, Kjaer T et al. (2011) No change in health behavior, BMI or self-rated health after a psychosocial cancer rehabilitation: Results of a randomized trial. Acta Oncol 50 (2): 289–98

    PubMed  Google Scholar 

  • Karvinen KH, Courneya KS, North S, Venner P (2007) Associations between exercise and quality of life in bladder cancer survivors: a population-based study. Cancer Epidemiol Biomarkers Prev 16 (5): 984–90

    PubMed  Google Scholar 

  • Keogh JW, Macleod RD (2011) Body Composition, Physical Fitness, Functional Performance, Quality of Life, and Fatigue Benefits of Exercise for Prostate Cancer Patients: A Systematic Review. J Pain Symptom Manage 2011 Jun 1. [Epub ahead of print]

    Google Scholar 

  • Kronenwetter C, Weidner G, Ornish D et al. (2005) A qualitative analysis of interviews of men with early stage prostate cancer: the Prostate Cancer Lifestyle Trial. Cancer Nurs 28 (2): 99–107

    PubMed  Google Scholar 

  • Krupski TL, Kwan L, Fink A et al. (2006) Spirituality influences health related quality of life in men with prostate cancer. Psychooncology 15 (2): 121–31

    PubMed  Google Scholar 

  • Leitzmann MF (2011) Physical activity and genitourinary cancer prevention. Recent Results Cancer Res 186: 43–71.

    PubMed  Google Scholar 

  • Lin KY, Hu YT, Chang KJ, Lin HF, Tsauo JY (2011) Effects of yoga on psychological health, quality of life, and physical health of patients with cancer: a meta-analysis. Evid Based Complement Alternat Med 2011: 659876

    Google Scholar 

  • Livingston PM, Salmon J, Courneya KS et al. (2011) Efficacy of a Referral and Physical Activity Program for Survivors of Prostate Cancer [ENGAGE]: Rationale and Design for a Cluster Randomised Controlled Trial. BMC Cancer 11 (1): 237

    PubMed Central  PubMed  Google Scholar 

  • Monga U, Garber SL, Thornby J et al. (2007) Exercise prevents fatigue and improves quality of life in prostate cancer patients undergoing radiotherapy. Arch Phys Med Rehabil 88 (11): 1416–22

    PubMed  Google Scholar 

  • Newton RU, Galvão DA (2008) Exercise in prevention and management of cancer. Curr Treat Options Oncol 9 (2–3): 135–46

    PubMed  Google Scholar 

  • NIH, National Center for Complementary and Alternative Medicine, http://nccam.nih.gov/health/backgrounds/mindbody.htm, Zugriff 12.1.06.

  • Ornish D, Scherwitz LW, Billings JH et al. (1998) Intensive lifestyle changes for reversal of coronary heart disease. JAMA 280 (23): 2001–7

    CAS  PubMed  Google Scholar 

  • Ornish D, Weidner G, Fair WR et al. (2005) Intensive lifestyle changes may affect the progression of prostate cancer. J Urol 174 (3): 1065–9; discussion 1069–70

    Google Scholar 

  • Ornish D, Lin J, Daubenmier J, Weidner G et al. (2008) Increased telomerase activity and comprehensive lifestyle changes: a pilot study: Lancet Oncol 9 (11): 1048–57. Erratum in: Lancet Oncol 2008

    CAS  PubMed  Google Scholar 

  • Ornish D, Magbanua MJ, Weidner G et al. (2008) Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle intervention: Proc Natl Acad Sci USA 105 (24): 8369–74. Epub 2008

    CAS  PubMed Central  PubMed  Google Scholar 

  • Overgard M, Angelsen A, Lydersen S et al. (2008) Does physiotherapist-guided pelvic floor muscle training reduce urinary incontinence after radical prostatectomy? A randomised controlled trial. European Urology 54: 438–448

    PubMed  Google Scholar 

  • Saxe G, Hebert J, Carmody J, Kabat-Zinn J et al. (2001) Can diet, in conjunction with stress reduction, affect the rate of increase in prostate-specific antigen after biochemical recurrence of prostate cancer? J Urology 66: 2202–2207

    Google Scholar 

  • Saxe G, Major JM, Nguyen JY et al. (2006) Potential attenuation of disease progression in recurrent prostate cancer with plant-based diet and stress reduction. Integr Cancer Ther 5 (3): 206–13

    PubMed  Google Scholar 

  • Segal RJ, Reid RD, Courneya KS et al. (2003) Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol 21 (9): 1653–9

    PubMed  Google Scholar 

  • Sommer F: Das Beckenbodenprogramm. In: Sommer F, Graf C (Hrsg.) Sports meets medicine – Urologie und Sport. Cuvillier, Göttingen

    Google Scholar 

  • Spahn G, Lehmann N, Dobos GJ et al. (2003) Improvement of fatigue and role function of cancer patients after an outpatient integrative mind/body intervention. FACT 8: 540

    Google Scholar 

  • Spiegel D (2001) Mind matters – group therapy and survival in breast cancer. N Engl J Med 345 (24)1767–8

    Google Scholar 

  • Tripathi A, Folsom AR, Anderson KE (2002) Risk factors for urinary bladder carcinoma in postmenopausal women. The Iowa Women’s Health Study. Cancer 95 (11): 2316–23

    PubMed  Google Scholar 

  • Windsor PM, Nicol KF, Potter J (2004) A randomized, controlled trial of aerobic exercise for treatment-related fatigue in men receiving radical external beam radiotherapy for localized prostate carcinoma. Cancer 101 (3): 550–7

    PubMed  Google Scholar 

  • Woll A, Bös K (2004) Wirkungen von Gesundheitssport. Bewegungstherapie und Gesundheitssport 20: 97–106

    Google Scholar 

Literatur zu ▶ Abschn. 16.4

  • Baier JE, Neumann HA, Gallati H, Ricken D (1991) Improvement of impaired mitogen-induced Interferon-gamma release of peripheral blood mononuclear Cells derived from tumor patients by Factor AF2 Res Exp Med 191: 281–289

    Google Scholar 

  • Bantel E, Engels IH, Voelter W et al. (1999) Misteltoe lectin activates caspace-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis. Cancer Res 59: 2083–90

    CAS  PubMed  Google Scholar 

  • Beuth J, Schierholz JM, Ko HL et al. (2001) Application-dependent immunomodulating and antimetastatic efficacy of thymic peptides in BALB/c-mice. In Vivo 15 (5): 403–406

    CAS  Google Scholar 

  • Beuth J, Schierholz JM, Mayer G (1999) Immunomodulating and antimetastatic activity of thymic peptides in BALB/c mice. Anticancer Res 19 (4B): 2993–2995

    CAS  PubMed  Google Scholar 

  • Beuth J, Schneider B, Schierholz JM (2008) Impact of complementary treatment of breast cancer patients with standardized mistletoe extract during aftercare: a controlled multicenter comparative epidemiological cohort study. Anticancer Res 28 (1B): 523–7

    CAS  PubMed  Google Scholar 

  • Bodey B, Bodey B Jr, Siegel SE et al. (2000) Review of thymic hormones in cancer diagnosis and treatment. Int J Immunopharmacol 22 (4): 261–273

    CAS  PubMed  Google Scholar 

  • Braun JM, Ko HL, Schierholz JM, Beuth J (2002) Standardized mistletoe extract augments immune response and down-regulates local and metastatic tumor growth in murine models. Anticancer Res 22 (6C): 4187–90

    CAS  PubMed  Google Scholar 

  • Burger AM, Mengs U, Schüler JB et al. (1999) Recombinant msitletoe lectin (ML) is a potent inhibitor of tumor cell growth in vitro and in vivo. Proceedings of the American Association for Cancer Research 40: 399

    Google Scholar 

  • Burger AM, Mengs U, Schüler JB et al. (2001) Anticancer activity of an aqueous mistletoe extract (AME) in syngenic murine tumor models. Anticancer Res 21: 1965–1968

    CAS  PubMed  Google Scholar 

  • Büssing A, Schietzel D, Schink M, Stein GM (2005) Keine Stimulation in vitro kultivierter Tumorzellen durch Mistellektin. In: Scheer R, Bauer R, Becker H et al. (Hrsg.) Fortschritte in der Misteltherapie. KVC-Verlag, Essen

    Google Scholar 

  • Büssing A, Tröger W, Stumpf C, Schietzel M (2008) Local reactions to treatments with Viscum album L. extracts and their association with T-lymphocyte subsets and quality of life. Anticancer Res 28 (3B): 1893–7

    PubMed  Google Scholar 

  • Büssing A, Vervecken W, Wagner M et al. (1999) Expression of mitochondrial Apo2.7 molecules and Caspase-3 activation in human lymphocytes treated with the ribosome-inhibiting mistletoe lectins and the cell membrane permeabilizing viscotoxins. Cytometry 37 (2): 133–9

    PubMed  Google Scholar 

  • Cazacu M, Oniu T, Lungoci C et al. (2003) The influence of isorel on the advanced colorectal cancer. Cancer Biother Radiopharm 18 (1): 27–34

    CAS  PubMed  Google Scholar 

  • Cramer R, Dri P, Spessotto P, Mittenzwei H, Patriarca P (1993) Potentiation of human polymorphonuclear leukocytes respiratory burst and phagoxytosis by a standardized liver and spleen fraction of peptides. Drug Res 43: 686–689

    CAS  Google Scholar 

  • Elluru SR, van Huyen JP, Delignat S et al. (2008) Induction of maturation and activation of human dendritic cells: a mechanism underlying the beneficial effect of Viscum album as complimentary therapy in cancer. BMC Cancer 8: 161

    PubMed Central  PubMed  Google Scholar 

  • Elsässer-Beile U, Leiber C, Mengs U et al. (2005) Adjuvant intravesical treatment with a standardized mistletoe extract to prevent recurrence of superficial urinary bladder cancer. J Urol 174 (1): 76–9

    PubMed  Google Scholar 

  • Elsässer-Beile U, Ruhnau T, Freudenberg N et al. (2001) Antitumoral effect of recombinant mistletoe lectin on chemically induced urinary bladder carcinogenesis in a rat model. Cancer 91 (5): 998–1004

    PubMed  Google Scholar 

  • Fidan I, Ozkan S, Gurbuz I et al. (2008) The efficiency of Viscum album ssp. album and Hypericum perforatum on human immune cells in vitro. Immunopharmacol Immunotoxicol 30 (3): 519–28

    CAS  PubMed  Google Scholar 

  • Gabius HJ, Darro F, Remmelink M et al. (2001) Evidence for stimulation of tumor proliferation in cell lines and histiotypic cultures by clinically relevant low doses of galactoside-binding mistletoe lectin, a component of proprietary extracts. Cancer Invest 19: 114–126

    CAS  PubMed  Google Scholar 

  • Goebell PJ, Otto T, Suhr J, Rübben H (2002) Evaluation of an unconventional treatment modality with mistletoe lectin to prevent recurrence of superficial bladder cancer: a randomized phase II trial. J Urol 168 (1): 72–5

    PubMed  Google Scholar 

  • Grossarth-Maticek R, Ziegler R (2007) Prospective controlled cohort studies on long-term therapy of cervical cancer patients with a mistletoe preparation (Iscador). Forsch Komplementmed 14 (3): 140–7

    PubMed  Google Scholar 

  • Grossarth-Maticek R, Ziegler R (2008) Randomized and non-randomized prospective controlled cohort studies in matched pair design for the long-term therapy of corpus uteri cancer patients with a mistletoe preparation (Iscador). Eur J Med Res 13 (3): 107–20

    CAS  PubMed  Google Scholar 

  • Horneber MA, Bueschel G, Huber R et al. (2008) Mistletoe therapy in oncology. Cochrane Database Syst Rev 2: CD003297

    PubMed  Google Scholar 

  • Hunziker-Basler N, Zuzak TJ, Eggenschwiler J et al. (2007) Prolonged cytotoxic effect of aqueous extracts from dried viscum album on bladder cancer cells. Pharmazie 62 (3): 237–8

    CAS  PubMed  Google Scholar 

  • Ivanov VI, Turdyev AA, Aleksandrova IA et al. (1987) Liver microso- mal lipids of mice irradiated and administered an extract turtle spleen. Radiobiologiia 27: 257–264

    CAS  PubMed  Google Scholar 

  • Kelter G, Schierholz JM, Fischer IU, Fiebig HH (2007) Cytotoxic activity and absence of tumor growth stimulation of standardized mistletoe extracts in human tumor models in vitro. Anticancer Res 27 (1A): 223–33

    PubMed  Google Scholar 

  • Kienle GS, Kiene H (2007) Complementary cancer therapy: a systematic rfeview of prospective clinical trials on anthroposophic mistletoe extracts. Eur J Med Res 12: 103–119

    CAS  PubMed  Google Scholar 

  • Kindler M (1997) Factor AF2 als Begleitmaßnahme zur Chemotherapie – myeloprotektive und antiemetische Wirkung. J Oncol 29: 7–10

    Google Scholar 

  • Kleeberg UR, Suciu S, Bröcker EB et al. (2004) Final results of the EORTC 18871/DKG 80-1 randomised phase III trial. rIFN-alpha2b versus rIFN-gamma versus ISCADOR M versus observation after surgery in melanoma patients with either high-risk primary (thickness >3 mm) or regional lymph node metastasis. Eur J Cancer 40 (3): 390–402

    CAS  PubMed  Google Scholar 

  • Klein AS, Shoham J (1981) Effect of the thymic facot, thymostimulin (TP-1), on the survival rate of tumor-bearing mice. Cancer Res 41 (8): 3217–3221

    CAS  PubMed  Google Scholar 

  • Klopp R, Schmidt W, Beuth J et al. (2005) Influence of complementary Viscum album (Iscador) administration on microcirculation and immune system of ear, nose and throat carcinoma patients treated with radiation and chemotherapy. Anticancer Res 25 (1B): 601–10

    CAS  PubMed  Google Scholar 

  • Kouttab NM, Prada M, Cazzola P (1989) Thymomodulin: biological properties and clinical applications. Med Oncol Tumor Pharmacother 6 (1): 5–9

    CAS  PubMed  Google Scholar 

  • Krege S, Hinke A, Otto T, Rübben H (2002) Bewertung des Komplementärtherapeutikums Factor AF2 als Supportivum in der Behandlung des Fortgeschrittenen Urothelkarzinoms Urologe A 41: 164–168

    Google Scholar 

  • Lange OF (1987) Supportive Therapie mit xenogenen Peptiden bei Patienten mit metastasiertem Mammakarzinom unter aggressiver Chemotherapie (modifiziertes AC-Schema), eine prospektive rando- misierte Doppelblindstudie. Onkologie 10 (Suppl): 40–43

    CAS  PubMed  Google Scholar 

  • Leder GH, Leder O (1990) Morpholigical studies on the subchronic toxicity of a standardized liver- and spleen-extract. Drug Res 40: 187–189

    CAS  Google Scholar 

  • Leroi R (1977) Postoperative Viscum album therapy after surgery of breast neoplasms. Helv Chir Acta 44 (3): 403–14

    CAS  PubMed  Google Scholar 

  • Maier G, Fiebig HH (2002) Absence of tumor growth stimulation in a panel of 16 human tumor cell lines by mistletoe extract in vitro. Anticancer Drugs 13: 373–9

    CAS  PubMed  Google Scholar 

  • Mengs U, Schwarz T, Bulitta M et al. (2000) Antitumoral effects of an intravesically applied aqueous mistletoe extract on urinary bladder carcinoma MB49 in mice. Anticancer Res 20: 3565–68

    CAS  PubMed  Google Scholar 

  • Naito S, Koga H, Yamaguchi A et al. (2008) Prevention of recurrence with epirubicin and lactobacillus casei after transurethral resection of bladder cancer. J Urol 179 (2): 485–90

    CAS  PubMed  Google Scholar 

  • Pae HO, Oh GS, Seo WG et al. (2001) Mistletoe lectin synergizes with paclitaxel in human SK-hep1 hepatocarcinoma cells. Immunopharmacol Immunotoxicol 23 (4): 531–40

    CAS  PubMed  Google Scholar 

  • Papadopulos I, Wand H (1989) Prüfung der Wirksamkeit von Factor AF2 auf die verbesserte Verträglichkeit des PE-Schemas (Epirubicin/Cisplatin) beim metastasierten Prostatakarzinom. Onkologie 12: 26–31

    Google Scholar 

  • Piao BK, Wang YX, Beuth J et al. (2004) Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients. A prospective randomized controlled clinical trial. Anticancer Res 24 (1): 303–9

    CAS  PubMed  Google Scholar 

  • Ribereau-Gayon G, Dumont S, Muller C et al. (1996) Mistletoe lectins I, II and III induce the production of cytokines by cultured human monocytes. Cancer Lett 109: 33–39

    CAS  PubMed  Google Scholar 

  • Salzer G et al. (1978) Prevention of recurrence of brandical carcinomas after surgery. Onkologie 1 (6): 264–7

    CAS  PubMed  Google Scholar 

  • Schierholz JM et al. (2003) Komplementäre Tumortherapie mit standardisiertem Mistelgesamtextrakt. Wissenschaft & Forschung 35: 186–94

    Google Scholar 

  • Schink M, Tröger W, Dabidian A et al. (2007) Mistletoe extract reduces the surgical suppression of natural killer cell activity in cancer patients. a randomized phase III trial. Forsch Komplementmed 14 (1): 9–17

    PubMed  Google Scholar 

  • Semiglasov VF, Stepula VV, Mengs U et al. (2004) The standardised mistletoe extract PS76A2 improves QoL in patients with breast cancer receiving adjuvant CMF chemotherapy: a randomised, placebo-controlled, double-blind, multicentre clinical trial. Anticancer Res 24 (2C): 1293–302

    CAS  PubMed  Google Scholar 

  • Simões-Wüst AP, Hunziker-Basler N, Zuzak J et al. (2007) Prolonged cytotoxic effect of aqueous extracts from dried Viscum album on bladder cancer cells. Forsch Komplementärmed 14 (supp 1): 28 (abstract)

    Google Scholar 

  • Steuer-Vogt MK, Bonkowsky V, Ambrosch P et al. (2001) The effect of an adjuvant mistletoe treatment programme in resected head and neck cancer patients: a randomised controlled clinical trial. Eur J Cancer 37 (1): 23–31

    CAS  PubMed  Google Scholar 

  • Stirpe F, Legg RF, Onyon LJ et al. (1980) Inhibition of protein synthesis by a toxic lectin from Viscum album L. (mistletoe). Biochem J 190: 843–5

    CAS  PubMed Central  PubMed  Google Scholar 

  • Urech K, Buessing A, Thalmann G et al. (2006) Antiproliferative effects of mistletoe extract in urinary bladder carcinoma cell lines. Anticancer Res 26: 3049–56

    PubMed  Google Scholar 

  • Wagner H, Röllinghoff M (1973) Cell-mediated immunity in vitro against syngeneic mouse plasma tumor cells. Nature 291: 53–54

    Google Scholar 

  • Visich KL, Yeo TP (2010) The prophylactic use of probiotics in the prevention of radiation therapy-induced diarrhea. Clin J Oncol Nurs 14 (4): 467–73

    PubMed  Google Scholar 

  • Wolf E, Milazzo S, Boehm K, Zwahlen M, Horneber M (2011) Thymic peptides for treatment of cancer patients. Cochrane Database Syst Rev 2:CD003993

    PubMed  Google Scholar 

  • Yagi, M, Yamashita T, Tsubura E (1985) Effect of a thymic factor, thymostimulin, on growth and pulmonary metastases of Lewis lung carcinoma. Cancer Immunol Immunother 19 (3): 198–204

    CAS  PubMed  Google Scholar 

Literatur zu ▶ Abschn. 16.5

  • Beuth J, Ost B, Pakdaman A et al. (2001) Impact of complementary oral enzyme application on the postoperative treatment results of breast cancer patients–results of an epidemiological multicentre retrolective cohort study. Cancer Chemother Pharmacol 47 (Suppl): S45–S54

    CAS  PubMed  Google Scholar 

  • Dörr W, Herrmann T et al. (2007) Efficacy of Wobe-Mugos E for reduction of oral mucositis after radiotherapy : results of a prospective, randomized, placebo-controlled, triple-blind phase III multicenter study. Strahlenther Onkol 183 (3): 121–7

    PubMed  Google Scholar 

  • Gujral M, Patnaik P, Kaul R et al. (2001) Efficacy of hydrolytic enzymes in preventing radiation therapy-induced side effects in patients with head and neck cancers. Cancer Chemother Pharmacol 47 (Suppl): S23–S28

    CAS  PubMed  Google Scholar 

  • Harrach T, Gebauer F, Eckert K et al. (1994) Bromelain proteases modulate the CD44 expression on human MOLT 4/8 leukaemia and SK-Mel 28 melanoma cells in vitro. Int J Oncol 5: 485

    CAS  PubMed  Google Scholar 

  • Lehmann P (1997) Immunomodulation by proteolytic enzymes. Nephrol Dial Transplant 11: 953

    Google Scholar 

  • Martin T, Uhder K, Kurek R et al. (2002) Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial. Radiother Oncol 65 (1): 17–22

    CAS  PubMed  Google Scholar 

  • Petru E, Stranz B, Petru C (2010) Effects of proteolytic enzyme therapy with Wobe Mugos against chemotherapy-induced toxicity in breast cancer patients - results of a pilot study. Wien Med Wochenschr 160 (19–20): 513–6

    PubMed  Google Scholar 

  • Popiela T, Kulig J, Hanisch J, Bock PR (2001) Influence of a complementary treatment with oral enzymes on patients with colorectal cancers–an epidemiological retrolective cohort study. Cancer Chemother Pharmacol 47 Suppl: S55–6

    Google Scholar 

  • Sakalova A, Bock P, Dedik L et al. (2001) Retrolective cohort study of an additive therapy with an oral enzyme preparation in patients with multiple myeloma. Cancer Chemother Pharmacol 47 (Suppl): S38–S44

    CAS  PubMed  Google Scholar 

  • Schedler M, Lind A, Schatzle W et al. (1990) Adjuvant therapy with hydrolytic enzymes in oncology: a hopeful effort to avoid bleomycin induced pneumotoxicity? J Cancer Res Clin Oncol 116: 697

    Google Scholar 

  • Wald M, Olejar T, Sebkova V et al. (2001) Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16. Cancer Chemother Pharmacol 47 (Suppl): S16–S22

    CAS  PubMed  Google Scholar 

  • Wolf M, Ransberger K (1968) Wirkung proteolytischer Enzyme auf die gegenseitige Wachstumsbeeinflussung von normalen und Tumorgeweben. Arch Geschwulstforsch 31: 317–331

    CAS  PubMed  Google Scholar 

  • Wrba H (1995) Krebstherapie mit proteolytischen Enymen. In: Kombinierte Tumortherapie, Hippokrates Verlag, Stuttgart, 2. Auflage 1995

    Google Scholar 

Literatur zu ▶ Abschn. 16.6

  • Adams KF, Chen C, Newton KM (2004) Soy isoflavones do not modulate prostate-specific antigen concentrations in older men in a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 13 (4): 644–8

    CAS  PubMed  Google Scholar 

  • Adhami VM, Ahmad N, Mukthar H (2003) Molecular targets for green tea in prostate cancer prevention. J Nutr 133 (Suppl 7): 2417S–2424S

    CAS  PubMed  Google Scholar 

  • Adlercreutz H, Honjo H, Higashi A et al. (1993) Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 342: 1209–1210

    CAS  PubMed  Google Scholar 

  • Bektic J, Berger AP, Pfeil K et al. (2004) Androgen receptor regulation by physicological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta. Eur Urol 45: 245–251

    CAS  PubMed  Google Scholar 

  • Bettuzzi S, Brausi M, Rizzi F et al. (2006) Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Research 66 (2): 1234–40

    CAS  PubMed  Google Scholar 

  • Bonham M, Posakony J, Coleman I et al. (2005) Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. Clin Cancer Res 11 (10): 3905–3914

    CAS  PubMed  Google Scholar 

  • Bonnar-Pizzorno RM, Littman AJ, Kestin M, White E (2006) Saw palmetto supplement use and prostate cancer risk. Nutr Cancer 55 (1): 21–7

    PubMed  Google Scholar 

  • Campbell G, Pickles T, D’yachkova Y (2003) A randomised trial of cranberry versus apple juice in the management of urinary symptoms during external beam radiation therapy for prostate cancer. Clin Oncol (R Coll Radiol) 15 (6): 322–8

    CAS  Google Scholar 

  • Carducci MA, Paller CJ, Wozniak P et al. (2011) A phase II study of pomegranate extract for men with rising prostate-specific antigen following primary therapy. J Clin Oncol 29 (suppl 7; abstr 11)

    Google Scholar 

  • Cassileth BR, Lucarelli CD (2003) Herb-drug interactions in oncology. Decker I, Hamilton London

    Google Scholar 

  • Castle EP, Thrasher JB (2002) The role of soy phytoestrogens in prostate cancer. Urol Clin North Am 29: 71–81

    PubMed  Google Scholar 

  • Chan JM, Elkin EP, Silva SJ et al. (2005) Total and specific complementary and alternative medicine use in a large cohort of men with prostate cancer. Urology 66 (6): 1223–1228

    CAS  PubMed  Google Scholar 

  • Choan E, Segal R, Jonker D et al. (2005) A prospective clinical trial of green tea for hormone refractory prostate cancer: an evaluation of the complementary/alternative therapy approach. Urologic Oncology 23 (2): 108–13

    CAS  PubMed  Google Scholar 

  • Cohen LA, Zhao Z, Pittman B et al. (2003) Effect of soy protein isolate and conjugated linoleic acid on the growth of Dunning R-3327-AT-1 rat prostate tumors. Prostate 54: 169–178

    CAS  PubMed  Google Scholar 

  • Dalais FS, Meliala A, Wattanapenpaiboon N (2004) Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer. Urology 64 (3): 510–5

    PubMed  Google Scholar 

  • De la Taille A, Buttyan R, Hayek O et al. (2000) Herbal therapy PC-SPES: In vitro effects and evaluation of its efficacy in 69 patients with prostate cancer. J Urol 164: 1229–1234

    CAS  PubMed  Google Scholar 

  • deVere White RW, Hackman RM et al. (2004) Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer. Urology 63 (2): 259–63

    PubMed  Google Scholar 

  • deVere White RW, Tsodikov A, Stapp EC et al. (2010) Effects of a high dose, aglycone-rich soy extract on prostate-specific antigen and serum isoflavone concentrations in men with localized prostate cancer. Nutr Cancer 62 (8): 1036–43

    CAS  PubMed Central  PubMed  Google Scholar 

  • Eng J, Ramsum D, Verhoef M et al. (2003) A population-based survey of complementary and alternative medicine use in men recently diagnosed with porstate cancer. Integr Cancer Ther 2 (3): 212–216

    PubMed  Google Scholar 

  • Evans BA, Griffiths K, Morton MS (1995) Inhibition of 5-alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J Endocrinol 147: 295–302

    CAS  PubMed  Google Scholar 

  • Fair WR, Fleshner NE, Heston W (1997) Cancer of the prostate: a nutritional disease. Urology 50: 840–848

    CAS  PubMed  Google Scholar 

  • Ferguson PJ, Kurowska E, Freeman DJ et al. (2004) A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines. J Nutr 134 (6): 1592–1535

    Google Scholar 

  • Fleshner NE, Kapusta L, Donnelly B et al. (2011) Progression from high-grade intraepithelial neoplasia to cancer: a randomized trial of combination vitamin-E, soy, and selenium. J Clin Oncol 29 (17): 2386–2390

    CAS  PubMed  Google Scholar 

  • Goldmann WH, Sharma AL, Currier SJ et al. (2001) Saw palmetto berry extract inhibits cell growth and Cox-2 expression in postatic cancer cells. Cell Biol Int 25 (11): 1117–1124

    CAS  PubMed  Google Scholar 

  • Grainger EM, Schwartz SJ, Wang S et al. (2008) A combination of tomato and soy products for men with recurring prostate cancer and rising prostate specific antigen. Nutr Cancer 60 (2): 145–54

    CAS  PubMed  Google Scholar 

  • Greenblatt DJ, von Moltke LL, Perloff ES et al. (2006) Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 79 (1): 125–33

    CAS  PubMed  Google Scholar 

  • Habib FK, Ross M, Ho CK et al. (2005) Serenoa repens (Permixon) inhibits the 5alpha-reductase activity of human prostate cancer cell lines without interfering with PSA expression. Int J Cancer 114 (2): 190–194

    CAS  PubMed  Google Scholar 

  • Hedelin M, Klint A, Chang ET et al. (2006) Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the cancer prostate Sweden study (Sweden). Cancer Causes Control 17 (2): 169–80

    PubMed  Google Scholar 

  • Hedlund TE, Johannes WU, Miller GJ (2003) Soy isoflavonoid equol modulates the growth of benign and malignant prostatic epithelial cells in vitro. Prostate 54: 68–78

    PubMed  Google Scholar 

  • Hill B, Kyprianou N (2004) Effect of permixon on human prostate cell growth: lack of apoptotic action. Prostate 61 (1): 73–80

    CAS  PubMed  Google Scholar 

  • Iglesias-Gato D, Carsten T, Vesterlund M et al. (2011) Androgen-independent Effects of Serenoa repens Extract (Prostasan®) on Prostatic Epithelial Cell Proliferation and Inflammation. Phytother Res 2011 Jun 8 [Epub ahead of print]

    Google Scholar 

  • Iguchi K, Okumura N, Usui S et al. (2001) Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human postatic LNCaP cells. Prostate 47 (1): 59–65

    CAS  PubMed  Google Scholar 

  • Jacobsen BK, Knutsen SF, Fraser GE (1998) Does high soy milk intake reduce prostate cancer incidence? The Adventist Health Study (United States). Cancer Causes Control 9: 553–557

    CAS  PubMed  Google Scholar 

  • Jain MG, Hislop GT, Howe GR et al. (1998) Alcohol and other beverage use and prostate cancer risk among Canadian men. Int J Cancer 78 (6): 707–11

    CAS  PubMed  Google Scholar 

  • Jatoi A, Ellison N, Burch PA et al. (2003) A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma. Cancer 97 (6): 1442–6

    CAS  PubMed  Google Scholar 

  • Jepson RG, Mihaljevic L, Craig J (2004) Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2004 (2): CD 001321

    Google Scholar 

  • Jian L, Xie LP, Lee AH, Binns CW (2004) Protective effect of green tea against prostate cancer: a case-control study in southeast China. Int J Cancer 108 (1): 130–5

    CAS  PubMed  Google Scholar 

  • Kikuchi et al. (2006) No association between green tea and prostate cancer risk in Japanese men: the Ohsaki Cohort Study. Br J Cancer 95 (3): 371–3

    Google Scholar 

  • Kranse R, Dagnelie PC, Schröder FH et al. (2005) Dietary intervention in prostate cancer patients: PSA response in a randomized double-blind placebo-controlled study. Int J Cancer 113 (5): 835–40

    CAS  PubMed  Google Scholar 

  • Kubota T, Hisatake J, Hisatake Y et al. (2000) PC-SPES: A unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo. Prostate 42: 163–171

    CAS  PubMed  Google Scholar 

  • Kumar NB, Cantor A, Allen K et al. (2004) The specific role of isoflavones in reducing prostate cancer risk. Prostate 59 (2): 141–7

    CAS  PubMed  Google Scholar 

  • Kumar NB, Krischer JP, Allen K et al. (2007) A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer. Nutrition & Cancer 59 (2): 163–8 und 169–75

    Google Scholar 

  • Kurahashi et al. (2008) Green tea consumption and prostate cancer risk in Japanese men: a prospective study. Am J Epidemiol 167 (1): 71–7

    Google Scholar 

  • Kurahashi N, Iwasaki M, Inoue M et al. (2007) Soy product and isoflavone consumption in relation to prostate cancer in Japanese men. Cancer Epidemiol Biomarkers Prev 16 (3): 538–45

    CAS  PubMed  Google Scholar 

  • Kwan W, Duncan G, Van Patten C et al. (2010) A phase II trial of a soy beverage for subjects without clinical disease with rising prostate-specific antigen after radical radiation for prostate cancer. Nutr Cancer 62 (2): 198–207

    CAS  PubMed  Google Scholar 

  • Kyle E, Neckers L, Takimoto C et al. (1997) Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity. Mol Pharmacol 51: 193–200

    CAS  PubMed  Google Scholar 

  • Landström M, Zhang JX, Hallmans G et al. (1998) Inhibitory effects of soy and rye diets on the development of Dunning R3327 prostate adenocarcinoma in rats. Prostate 36: 151–161

    PubMed  Google Scholar 

  • Lansky EP, Harrison G, Froom P et al. (2005) Pomgranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel. Invest New Drugs 23: 121–2

    CAS  PubMed  Google Scholar 

  • Lazarevic B, Boezelijn G, Diep LM et al. (2011) Efficacy and Safety of Short-Term Genistein Intervention in Patients with Localized Prostate Cancer Prior to Radical Prostatectomy: A Randomized, Placebo-Controlled, Double-Blind Phase 2 Clinical Trial. Nutr Cancer 2011 Jun 29. [Epub ahead of print]

    Google Scholar 

  • Lee MM, Gomez SL, Chang JS et al. (2003) Soy and isoflavone consumption in relation to prostate cancer risk in China. Cancer Epidemiol Biomarker Prev 12: 665–8

    CAS  Google Scholar 

  • Lee SC, Chan WK, Lee TW et al. (2008) Effect of a prodrug of the green tea polyphenol (-)-epigallocatechin-3–gallate on the growth of androgen-independent prostate cancer in vivo. Nutr Cancer 60 (4): 483–91

    CAS  PubMed  Google Scholar 

  • Li XM, Li J, Tsuji I, Nakaya N et al. (2008) Mass screening-based case-control study of diet and prostate cancer in Changchun, China. Asian J Androl 10 (4): 551–60

    CAS  PubMed  Google Scholar 

  • Linde K, Barrett B, Wölkart K et al. (2006) Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev. (1):CD000530

    Google Scholar 

  • Linde K, Berner MM, Kriston L (2008) St John’s wort for major depression. Cochrane Database Syst Rev (4): CD000448

    Google Scholar 

  • Mantovani F (2010) Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol Nefrol 62 (4): 335–40

    CAS  PubMed  Google Scholar 

  • McLarty J, Bigelow RL, Smith M et al. (2009) Tea polyphenols decrease serum levels of prostate-specific antigen, hepatocyte growth factor, and vascular endothelial growth factor in prostate cancer patients and inhibit production of hepatocyte growth factor and vascular endothelial growth factor in vitro. Cancer Prev Res (Phila). 2 (7): 673–82

    Google Scholar 

  • Mörike K, Gleiter DH (2003) Pflanzliche Arzneimittel. Internist 44: 748–752

    PubMed  Google Scholar 

  • Mousavi Y, Adlercreutz H (1993) Genistein is an effective stimulator of sex hormone-binding globulin production in hepatocarcinoma human liver cancer cells and suppresses proliferation of these cells in culture. Steroids 58: 301–304

    CAS  PubMed  Google Scholar 

  • Murphy BT, MacKinnon SL, Yan X et al. (2003) Identification of triterpene hydroxycinnamates with in vitro antitumor activity from whole cranberry fruit (Vaccinium macrocarpon). J Agric Food Chem 51 (12): 3541–5

    CAS  PubMed  Google Scholar 

  • Nakamura H, Wang Y, Kurita T et al. (2011) Genistein increases epidermal growth factor receptor signaling and promotes tumor progression in advanced human prostate cancer. PLoS One 6 (5):e20034. Epub 2011 May 16

    Google Scholar 

  • Pantuck AJ, Leppert JT, Zomorodian N (2006) Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Clin Cancer Res 12 (13): 4018–26

    CAS  PubMed  Google Scholar 

  • Paschka AG, Butler R, Young CY (1998) Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate. Cancer Letters 130 (1–2): 1–7

    CAS  PubMed  Google Scholar 

  • Pendleton (2008) Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy. BMC Cancer 8: 132

    PubMed Central  PubMed  Google Scholar 

  • Santibanez JF, Navarro A, Martinez J (1997) Genistein inhibits proliferation and in vitro invasive potential of human prostatic cancer cell lines. Anticancer Res 17: 1199–1204

    CAS  PubMed  Google Scholar 

  • Schröder FH, Roobol MJ, Boevé ER et al. (2005) Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement. Eur Urol 48 (6): 922–30

    PubMed  Google Scholar 

  • Seeram NP, Adams LS, Hardy ML et al. (2004) Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines. J Agric Food Chem 52 (9): 2512–7

    CAS  PubMed  Google Scholar 

  • Shabbir M, Love J, Montgomery B (2008) Phase I trial of PC-Spes2 in advanced hormone refractory prostate cancer. Oncol Rep 19 (3): 831–5

    PubMed  Google Scholar 

  • Sinescu I, Geavlete P, Multescu R et al. (2011) Long-term efficacy of Serenoa repens treatment in patients with mild and moderate symptomatic benign prostatic hyperplasia. Urol Int 86 (3): 284–9

    PubMed  Google Scholar 

  • Sovak M, Seligson AL, Konas M et al. (2002) Herbal composition PC-SPES for management of prostate cancer: Identification of active principles. J Natl Cancer Inst 94: 1275–1281

    CAS  PubMed  Google Scholar 

  • Sparreboom A, Cox MC, Acharya MR et al. (2004) Herbal remedies in the United States: potential adverse interactions with anticancer agents. J Clin Oncol 22 (12): 2489–2503

    CAS  PubMed  Google Scholar 

  • Stearns ME, Wang M (2011) Synergistic Effects of the Green Tea Extract Epigallocatechin-3-gallate and Taxane in Eradication of Malignant Human Prostate Tumors. Transl Oncol 4 (3): 147–56

    PubMed Central  PubMed  Google Scholar 

  • Sun CL, Yuan JM, Wang XL et al. (2004) Dietary soy and increased risk of bladder cancer: a prospective cohort study of men in Shanghai, China. Int J Cancer 112 (2): 319–23

    CAS  PubMed  Google Scholar 

  • Sverson KJ, Noura AMY, Grove JS et al. (1989) A prospective study of demographics, diet and prostate cancer among men of Japanese ancestry in Hawaii. Cancer Res 49: 1857–1860

    Google Scholar 

  • Tacklind J, MacDonald R, Rutks I, Wilt TJ (2009) Serenoa repens for benign prostatic hyperplasia. Cochrane Database Syst Rev. (2):CD001423

    Google Scholar 

  • Thomas F, Patel S, Holly JM et al. (2008) Dihydrotestosterone sensitises LNCaP cells to death induced by epigallocatechin-3-gallate (EGCG) or an IGF-i receptor inhibitor. Prostate [Epub ahead of print]

    Google Scholar 

  • Thomas F, Holly JM, Persad R, Bahl A, Perks CM (2011) Green Tea Extract (Epigallocatechin-3-Gallate) Reduces Efficacy of Radiotherapy on Prostate Cancer Cells. Urology 2011 Jun 13. [Epub ahead of print]

    Google Scholar 

  • Von Löw EC, Perabo FG, Siener R, Müller SC (2007) Review. Facts and fiction of phytotherapy for prostate cancer: a critical assessment of preclinical and clinical data. In Vivo 21 (2): 189–204

    Google Scholar 

  • Wilt T, Ishani A, Mac Donald R (2002) Serenoa repens for benign postatic hyperplasia. Cochrane Database Syst Rev 2002 (3)

    Google Scholar 

  • Zheng J, Yang B, Huang T et al. (2011) Green tea and black tea consumption and prostate cancer risk: an exploratory meta-analysis of observational studies. Nutr Cancer 63 (5): 663–72

    CAS  PubMed  Google Scholar 

Literatur zu ▶ Abschn. 16.7

  • Balzarini A, Felisi E, Martini A et al. (2000) Efficacy of homeopathic treatment of skin reactions during radiotherapy for breast cancer, A randomised, double-blind clinical trial. Brit Hom J 89 (1): 8–12

    CAS  Google Scholar 

  • Jonas WB, Gaddipati JP, Rajeshkumar NV et al. (2006) Can homeopathic treatment slow prostate cancer growth? Integr Cancer Ther 5 (4): 343–9

    PubMed  Google Scholar 

  • Linde K, Clausius N, Ramirez G et al. (1997) Are the clinical effects of homeopathy placebo effects ? A meta-analysis of placebo-controlled trials. Lancet 350: 834–843

    CAS  PubMed  Google Scholar 

  • MacLaughlin BW, Gutsmuths B, Pretner E, Jonas WB et al. (2006) Effects of homeopathic preparations on human prostate cancer growth in cellular and animal models. Integr Cancer Ther 5 (4): 362–72

    PubMed  Google Scholar 

  • Oberbaum M, YanivI, Ben-Gal Y et al. (2001) A randomized, controlled clinical trial of the homeopathic medication Traumeel S in the treatment of chemotherapy-induced stomatitis in children undergoing stem cell transplantation. Cancer 92 (3): 684–690

    CAS  PubMed  Google Scholar 

  • Rostock M, Naumann J, Guethlin C et al. (2011) Classical homeopathy in the treatment of cancer patients–a prospective observational study of two independent cohorts. BMC Cancer 11: 19

    PubMed Central  PubMed  Google Scholar 

  • Thompson EA, Reilly D (2002) The homeopathic approach to symptom control in the cancer patient: a prospective observational study. Palliative Med 16: 227–233

    CAS  Google Scholar 

Literatur zu ▶ Abschn. 16.8

  • Badtke G, Mudra I (1998) Neuraltherapie, Lehrbuch und Atlas, Ullstein Medical, Wiesbaden

    Google Scholar 

  • Barop H (1996) Lehrbuch und Atlas Neuraltherapie nach Huneke, Hippokrates, Stuttgart

    Google Scholar 

  • Dosch P (1995) Lehrbuch der Neuraltherapie nach Huneke, Haug, Heidelberg

    Google Scholar 

  • Fischer L (1998) Neuraltherapie nach Huneke, Hippokrates, Stuttgart

    Google Scholar 

  • Villar-Garea A, Fraga MF, Espada J et al. (2003) Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res 63 (16): 4984–4989

    CAS  PubMed  Google Scholar 

  • Weinschenk S (2010), Handbuch der Neuraltherapie, Elsevier, München

    Google Scholar 

Literatur zu ▶ Abschn. 16.9

  • Haker E, Egekvist H, Bjerring P (2000) Effect of sensory stimulation (acupuncture) on sympathetic and parasympathetic activities in healthy subjects. J Auton Nerv Syst 79: 52–9

    CAS  PubMed  Google Scholar 

  • Han JS, Terenius L (1982) Neurochemical basis of acupuncture analgesia. Annu Rev Pharmacol Toxicol 22: 193–220

    CAS  PubMed  Google Scholar 

  • Heine H (1988) Funktionelle Morphologie der Akupunkturpunkte. Akupunktur-Theorie und Praxis 1: 4

    Google Scholar 

  • Johnston MF, Ortiz Sanchez E et al. (2011) Acupuncture may stimulate anticancer immunity via activation of natural killer cells. Evidence-Based Complementary and Alternative Medicine, Article ID 481625.

    Google Scholar 

  • Johnstone PA, Polston GR, Niemtzow RC, Martin PJ (2002) Integration of acupuncture into the oncology clinic. Palliat Med 16 (3): 235–9

    PubMed  Google Scholar 

  • Kou W, Bell JD, Gareus I et al. (2005) Repeated acupuncture treatment affects leucocyte circulation in healthy young male subjects: a randomized single-blind two-period crossover study. Brain Behav Immune 19 (4): 318–324

    Google Scholar 

  • Lehmann HJ (1999) Akupunkturpraxis – Chinesische Standardtherapie mit Relevanzkarten. Urban & Fischer, München

    Google Scholar 

  • Melchart D, Streng A, Hoppe A et al. (2006) Akupunktur bei chronischen Schmerzen: Ergebnisse aus dem Modellvorhaben der Ersatzkassen. Dtsch Arztebl 2006 103 (4): A 187–95

    Google Scholar 

  • NIH Consensus Statement Online (1997) Acupuncture 15 (5): 1–34

    Google Scholar 

  • Weingarden H, Ring H (2006) Functional electrical stimulation-induced neural changes and recovery after stroke. Eura Medicophys 42: 87–90

    CAS  PubMed  Google Scholar 

  • Witt C, Brinkhaus B, Jena S et al. (2006) Wirksamkeit, Sicherheit und Wirtschaftlichkeit der Akupunktur – Ein Modellvorhaben mit der Techniker Krankenkasse. Dtsch Arztebl 103 (4): A 196–202

    Google Scholar 

  • Zhang X, Yuan Y, Kuang P et al. (1999) Effects of electro-acupuncture on somatostatin and pancreatic polypeptide in ischemic cerebrovascular diseases. J Tradit Chin Med 19: 54–8

    CAS  PubMed  Google Scholar 

Literatur zu ▶ Abschn. 16.10

  • Arzneimittelkommission der deutschen Ärzteschaft (2001) Zur Anwendung des Präparates „Galavit“ in der Krebstherapie. Dtsch Ärztebl 98 (15): A1016

    Google Scholar 

  • Dandekar DS, Lokeshwar VB, Cevallos-Arellano E, Soloway MS, Lokeshwar BL (2003) An orally active Amazonian plant extract (BIRM) inhibits prostate cancer growth and metastasis. Cancer Chemother Pharmacol 52: 59–66

    CAS  PubMed  Google Scholar 

  • Blackadar C (1993) Skeptics of oral administration of shark cartilage. J Natl Cancer Inst 85: 1961–1962

    CAS  PubMed  Google Scholar 

  • Loprinzi C, Levitt R, Barton D et al. (2005) Evalutation of shark cartilage in patients with advanced cancer: a North Central Cancer Treatment Group trial. Cancer 104 (1): 176–182

    PubMed  Google Scholar 

  • O`Brian B, Quigg C, Leong T (2005) Severe cyanice toxicity from „vitamin supplements“. Eur J Emerg Med 12 (5): 257–258

    Google Scholar 

  • Park HJ, Yoon SH, Han LS et al. (2005) Amygdalin inhibits genes related to cell-cycle in SNU-C4 human colon cancer cells. World J Gastroenterol 1 (33): 5156–5161

    Google Scholar 

  • Sheu J, Fu C, Tsai M et al. (1998) Effect of U-995, a potent shark cartilage-derived angiogenesis inhibitor, on anti-angiogenesis and anti-tumor activities. Anticancer Res 18: 4435–4441

    CAS  PubMed  Google Scholar 

Literatur zu Kap. ▶ Abschn. 16.11

  • Abbasi Nazari et al. (2007) Allopurinol mouthwash for prevention or alleviation radiotherapy induced oral mucositis: a randomized, placebo-controlled trial. DARU 15 (4): 227–230

    Google Scholar 

  • Alimi D, Rubino C, Pichard-Leandri E et al. (2003) Analgesic effect of auricular acupuncture for cancer pain: a randomized, blinded, controlled trial. Clin Oncol 21: 4120–26

    Google Scholar 

  • Altschuler A, Rosenbaum E, Gordon P, Canales S, Avins AL (2011) Audio recordings of mindfulness-based stress reduction training to improve cancer patients’ mood and quality of life-a pilot feasibility study. Support Care Cancer 2011 Jun 19. [Epub ahead of print]

    Google Scholar 

  • Andersen C, Adamsen L, Moeller T et al. (2006) The effect of a multidimensional exercise programme on symptoms and side-effects in cancer patients undergoing chemotherapy. Eur J Oncol Nurs 10 (4): 247–62

    PubMed  Google Scholar 

  • Argyriou AA, Chroni E, Koutras A et al. (2006a) Preventing paclitaxel-induced peripheral neuropathy: a phase II trial of vitamin E supplementation. J Pain Symptom Manage 32 (3): 237–44

    CAS  Google Scholar 

  • Argyriou AA, Chroni E, Koutras A et al. (2006b) A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results. Support Care Cancer 14: 1134–1140

    Google Scholar 

  • Armes J, Chalder T, Addington-Hall J et al. (2007) A randomized controlled trial to evaluate the effectiveness of a brief, behaviorally oriented intervention for cancer-related fatigue. Cancer 110 (6): 1385–95

    PubMed  Google Scholar 

  • Arnim von U, Peitz U, Malfertheiner P et al. (2007) STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. Am J Gastroenterol 102 (6): 1268–75

    Google Scholar 

  • Ashamalla H, Jiang ML, Guirguis A et al. (2011) Acupuncture for the alleviation of hot flashes in men treated with androgen ablation therapy. Int J Radiat Oncol Biol Phys 79 (5): 1358–63

    PubMed  Google Scholar 

  • Barsevick AM, Dudley W, Beck S et al. (2004) A randomized clinical trial of energy conservation for patients with cancer-related fatigue. Cancer 100: 1302–1310

    PubMed  Google Scholar 

  • Beer TM, Benavides M, Emmons SL et al. (2010) Acupuncture for hot flashes in patients with prostate cancer. Urology 76 (5): 1182–8

    PubMed Central  PubMed  Google Scholar 

  • Biesbroeck R, Bril V, Hollander P et al. (1995) A double-blind comparison of topical capsaicin and oral amitriptyline in painful diabetic neuropathy. Advances in Therapy 12 (2): 111–120

    CAS  PubMed  Google Scholar 

  • Bill-Axelson A, Garmo H et al. (2011) Psychiatric treatment in men with prostate cancer - Results from a Nation-wide, population-based cohort study from PCBaSe Sweden. Eur J Cancer 2011 May 23. [Epub ahead of print]

    Google Scholar 

  • Bishop SR, Warr D (2003) Coping, catastrophizing and chronic pain in breast cancer. J Behav Med 26: 265–81

    PubMed  Google Scholar 

  • Biswal BM, Zakaria A, Ahmad NM (2003) Topical application of honey in the management of radiation mucositis. A preliminary study. Supportive Care in Cancer 11 (4): 242–8

    PubMed  Google Scholar 

  • Blom M, Lundeberg T (2000) Long-term follow-up of patients treated with acupuncture for xerostomia and the influence of additional treatment. Oral Dis 6: 15–24

    CAS  PubMed  Google Scholar 

  • Borowski B, Benhamou E, Pico JL et al. (1994) Prevention of oral mucositis in patients treated with high-dose chemotherapy and bone marrow transplantation: a RCT comparing two protocols of dental care. Eur J Cancer B Oral Oncol 30B: 93–97

    CAS  PubMed  Google Scholar 

  • Bove L, Picardo M, Pace A et al. (2001) A pilot study on the relation between cisplatin neuropathy and vitamin E. J Experim & Clin Cancer Res 20: 277–280

    CAS  Google Scholar 

  • Brietbart W, Payne D, Passik SD (2004) Psychological and psychiatric interventions in pain control. In: Doyle D, Hanks NC, Calman K: Oxford Textbook of Palliative Medicine. 3rd ed. New York. Oxford University Press: 424–38

    Google Scholar 

  • Burish TG, Jenkins RA (1992) Effectiveness of biofeedback and relaxation training in reducing the side effects of cancer chemotherapy. Health Psychol 11: 17–23

    CAS  PubMed  Google Scholar 

  • Burish TG, Snyder SL, Jenkins RA (1991) Preparing patients for cancer chemotherapy: Effect of coping, preparation and relaxation interventions. J Consult Clin Psychol 59: 518–525

    CAS  PubMed  Google Scholar 

  • Campbell G, Pickles T, D’yachkova Y (2003) A randomised trial of cranberry versus apple juice in the management of urinary symptoms during external beam radiation therapy for prostate cancer. Clin Oncol (R Coll Radiol) 15 (6): 322–8

    CAS  Google Scholar 

  • Capodice JL et al. (2008) Results of a prospective pilot clinical trial administering acupuncture for hot flashes in patients undergoing hormonal therapy for prostate cancer. J Urol 179 (Suppl 4): 184–5

    Google Scholar 

  • Carlson LE, Garland SN (2005) Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients. Int J Behav Med 12 (4): 278–85

    PubMed  Google Scholar 

  • Carlson LE, Speca M et al. (2003) Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med 65 (4): 571–81

    PubMed  Google Scholar 

  • Carlson LE, Speca M, Faris P, Patel KD (2007) One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain Behav Immun 21 (8): 1038–49

    CAS  PubMed  Google Scholar 

  • Carlson LE, Ursuliak Z, Speca M et al. (2001) The effects of mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer patients: 6-month follow-up. Support Care Cancer 9: 112–123

    CAS  PubMed  Google Scholar 

  • Carson JW, Porter LS, Keefe FJ et al. (2007) Yoga for women with metastatic breast cancer: results from a pilot study. J Pain Symptom Manage 33 (3): 331–341

    PubMed  Google Scholar 

  • Cascinu S, Fedeli A, Fedeli SL, Catalano G (1994) Oral cooling (cryotherapy), an effective treatment for the prevention of 5-fluorouracil-induced stomatitis. European Journal of Cancer Part B, Oral Oncology 30B: 234–6

    CAS  Google Scholar 

  • Cella D, Davis K, Breitbart W et al. (2001) Cancer-Related Fatigue: Prevalence of Proposed Diagnostic Criteria in a United States Sample of Cancer Survivors. J Clin Oncol 19: 3385–3391

    CAS  PubMed  Google Scholar 

  • Centemero A, Rigatti L, Giraudo D et al. (2010) Preoperative pelvic floor muscle exercise for early continence after radical prostatectomy: a randomised controlled study. Eur Urol 57 (6): 1039–43

    PubMed  Google Scholar 

  • Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S et al. (2006) The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol 194 (1): 95–9

    PubMed  Google Scholar 

  • Clark PI, Slevin ML (1985) Allopurinol mouthwash and 5-FU induced oral toxicity. Eur J Surg Oncol 11: 267–268

    CAS  PubMed  Google Scholar 

  • Cotanch PH, Strum S (1987) Progressive muscle relaxation as antiemetic therapy for cancer patients. Oncol Nurs Forum 14: 33–37

    CAS  PubMed  Google Scholar 

  • Cramp F, Daniel J. (2008) Exercise for the management of cancer-related fatigue in adults. Cochrane Database Syst Rev. (2):CD006145

    Google Scholar 

  • Dang W, Yang J (1998) Clinical study on acupuncture treatment of stomach carcinoma pain. J Tradit Chin Med 18: 31–38

    CAS  PubMed  Google Scholar 

  • Deng G, Vickers A, Cassileth B et al. (2007) Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients. J Clin Oncol 25 (35): 5584–90

    PubMed  Google Scholar 

  • Dibble SL, Luce J, Cooper BA et al. (2007) Acupressure for chemotherapy-induced nausea and vomiting: a randomized clinical trial. Oncol Nurs Forum 34 (4): 813–20

    PubMed  Google Scholar 

  • Dillon M, Lucas C (1999) Auricular stud acupuncture in palliative care patients. Palliat Med 13: 253–254

    CAS  PubMed  Google Scholar 

  • Dimeo FC, Schwartz S, Wesel N et al. (2008) Effects of an endurance and resistance exercise program on persistent cancer-related fatigue after treatment. Ann Oncol 19 (8): 1495–9

    CAS  PubMed  Google Scholar 

  • Dimeo FC, Thomas F, Raabe-Menssen C et al. (2004) Effect of aerobic exercise and relaxation training on fatigue and physical performance of cancer patients after surgery. Support Care Cancer 12 (11): 774–9

    PubMed  Google Scholar 

  • Dodd MJ, Dibble SL, Miaskowski C et al. (2000) Randomized clinical trial of the effectiveness of 3 commonly used mouthwashes to treat chemotherapy-induced mucositis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90: 39–47

    CAS  PubMed  Google Scholar 

  • Donofrio et al. (1991) Treatment of painful diabetic neuropathy with topical capsaicin – a multicenter, double-blind, vehicle-controlled study. Archives of Internal Medicine 151 (11): 2225–2229

    Google Scholar 

  • Ezzo J, Streitberger K, Schneider A (2006) Acupuncture-point stimulation for chemotherapy-induced nausea or vomiting. Cochrane Database of Systematic Reviews 2: CD002285

    PubMed  Google Scholar 

  • Faithfull S, Cockle-Hearne J, Khoo V (2011) Self-management after prostate cancer treatment: evaluating the feasibility of providing a cognitive and behavioural programme for lower urinary tract symptoms. BJU Int 107 (5): 783–90

    PubMed  Google Scholar 

  • Fawzy FI, Cousins N, Fawzy NW et al. (1990) A structured psychiatric intervention for cancer patients. Arch Gen Psych 47: 720–5

    CAS  Google Scholar 

  • Fenlon DR, Corner JL, Haviland JS (2008) A randomized controlled trial of relaxation training to reduce hot flashes in women with primary breast cancer. J Pain Symptom Manage 35 (4): 397–405

    PubMed  Google Scholar 

  • Ferrer M, Suárez JF, Guedea F et al. (2008) Health-related quality of life 2 years after treatment with radical prostatectomy, prostate brachytherapy, or external beam radiotherapy in patients with clinically localized prostate cancer. Int J Radiat Oncol Biol Phys 72 (2): 421–32

    PubMed  Google Scholar 

  • Filshie J (1990) Acupucnture for malignant pain. Acupunct Med 8 (2): 38–39

    Google Scholar 

  • Filshie J, Bolton T, Browne D, Ashley S (2006) Acupuncture and self acupuncture for long-term treatment of vasomotor symptoms in cancer patients–audit and treatment algorithm. Acupunct Med 24 (2): 92–4

    Google Scholar 

  • Filshie J, Redman D (1985) Acupuncture and malignant pain problems. Eur J Surg oncol 11: 389–394

    Google Scholar 

  • Filshie J, Thompson JW (2004) Acupuncture. In: Doyle D, Hanks NC, Calman K: Oxford Textbook of Palliative Medicine. 3rd ed. New York. Oxford University Press: 410–24

    Google Scholar 

  • Frank SJ, Pisters LL, Davis J et al. (2007) An assessment of quality of life following radical prostatectomy, high dose external beam radiation therapy and brachytherapy iodine implantation as monotherapies for localized prostate cancer. J Urol 177 (6): 2151–6

    PubMed  Google Scholar 

  • Frisk J, Carlhäll S, Hammar M et al. (2008) Long-term follow-up of acupuncture and hormone therapy on hot flushes in women with breast cancer: a prospective, randomized, controlled multicenter trial. Climacteric 11 (2): 166–74

    CAS  PubMed  Google Scholar 

  • Frisk J, Spetz AC, Hjertberg H et al. (2009) Two modes of acupuncture as a treatment for hot flushes in men with prostate cancer–a prospective multicenter study with long-term follow-up. Eur Urol 55 (1): 156–63

    PubMed  Google Scholar 

  • Galvão DA, Taaffe DR, Spry N, Newton RU (2011) Physical activity and genitourinary cancer survivorship. Recent Results Cancer Res 186: 217–36

    PubMed  Google Scholar 

  • Gardani G, Cerrone R, Biella C (2007) A progress study of 100 cancer patients treated by acupressure for chemotherapy-induced vomiting after failure with the pharmacological approach. Minerva Med 98 (6): 665–8

    CAS  PubMed  Google Scholar 

  • Genuis ML (1995) The use of hypnosis in helping cancer patients control anxiety, pain, and emesis: a review of recent empirical studies. Am J Clin Hypn 37: 316–325

    CAS  PubMed  Google Scholar 

  • Gielissen MF, Verhagen CA, Bleijenberg G (2007) Cognitive behaviour therapy for fatigued cancer survivors: long-term follow-up. Br J Cancer 97 (5): 612–8

    CAS  PubMed Central  PubMed  Google Scholar 

  • Given B, Given CW, McCorkle R et al. (2002) Pain and fatigue management: Results of a nursing RCT. Oncol Nurs Forum 29

    Google Scholar 

  • Gottschling S, Reindl TK et al. (2008) Acupuncture to alleviate chemotherapy-induced nausea and vomiting in pediatric oncology – a randomized multicenter crossover pilot trial. Klin Padiatr 220 (6): 365–70

    CAS  PubMed  Google Scholar 

  • Guo R, Zhang L, Gong Y, Zhang B (1995) The treatment of pain in bone metastasis of cancer with the analgesic decoction of cancer and the acupoint therapeutic apparatus. J Tradit Chin Med 15: 262–264

    CAS  PubMed  Google Scholar 

  • Harding C, Harris A, Chadwick D (2009) Auricular acupuncture: a novel treatment for vasomotor symptoms associated with luteinizing-hormone releasing hormone agonist treatment for prostate cancer. BJU Int 103 (2): 186–90

    PubMed  Google Scholar 

  • Hayes RB et al. (2005) Acupuncture for hot flashes in prostate cancer patients. JCO 23 (Suppl 16): 8160

    Google Scholar 

  • Hickok JT, Roscoe JA, Morrow GR, Ryan JL (2007) A phase II/III randomized, placebo-controlled, double-blind clinical trial of ginger (Zingiber officinale) for nausea caused by chemotherapy for cancer: a currently accruing URCC CCOP Cancer Control Study. Support Cancer Ther 4 (4): 247–50

    PubMed  Google Scholar 

  • Hofmann SG, Sawyer AT, Witt AA, Oh D (2010) The effect of mindfulness-based therapy on anxiety and depression: A meta-analytic review. J Consult Clin Psychol 78 (2): 169–83.

    PubMed Central  PubMed  Google Scholar 

  • Huang GX, Zhao C, Han F et al. (2003) Clinical study in prophylactic use of chinesemedicine to prevent chemoradiotherapy induced mucositis in nasopharyngeal carcinoma. Ai Zheng 22 (10): 1084–7

    PubMed  Google Scholar 

  • Jadad AR, Browman GP (1995) The WHO analgesic ladder for cancer pain management: stepping up the quality of ist evaluation. JAMA 274: 1870–1873

    CAS  PubMed  Google Scholar 

  • Johnstone PA, Bloom TL, Niemtzow RC et al. (2003) A prospective, randomized pilot trial of acupuncture of the kidney-bladder distinct meridian for lower urinary tract symptoms. J Urol 169 (3): 1037–9

    PubMed  Google Scholar 

  • Johnstone PA, Niemtzow RC, Riffenburgh RH (2002) Acupuncture for xerostomia: clinical update. Cancer 94 (4): 1151–6

    PubMed  Google Scholar 

  • Johnstone PA, Peng YP, May BC et al. (2001) Acupuncture for pilocarpine-resistant xerostomia following radiotherapy for head and neck malignancies. Int J Radiat Oncol Biol Phys 50 (2): 353–7

    CAS  PubMed  Google Scholar 

  • Jung S, Lee E-N, Lee, S-R et al. (2012) Tai Chi for lower urinary tract symptoms and quality of life in elderly patients with benign prostate hypertrophy: a randomized controlled trial. Evidence-Based Compl and Altern Med, Vol 2012, Art ID 624692

    Google Scholar 

  • Kabat-Zinn J, Lipworth L, Burney R (1985) The clinical use of mindfulness meditation for the self-regulation of chronic pain. J Behav Med 8: 163–190

    CAS  PubMed  Google Scholar 

  • Keefe FJ, Abernethy AP, Campbell LC (2005) Psychological approaches to understanding and treating disease-related pain. Annu Rev Psychol 56: 601–630

    PubMed  Google Scholar 

  • Keogh JW, Macleod RD (2011) Body Composition, Physical Fitness, Functional Performance, Quality of Life, and Fatigue Benefits of Exercise for Prostate Cancer Patients: A Systematic Review. J Pain Symptom Manage 2011 Jun 1. [Epub ahead of print]

    Google Scholar 

  • Kim S, Kim H (2005) Effects of a relaxation breathing exercise on fatigue in haemopoietic stem cell transplantation patients. J Clin Nurs 14: 51–55

    PubMed  Google Scholar 

  • Kutner JS, Smith MC, Corbin L et al. (2008) Massage therapy versus simple touch to improve pain and mood in patients with advanced cancer: a randomized trial. Ann Intern Med 149 (6): 369–79

    PubMed Central  PubMed  Google Scholar 

  • Lee J, Dodd MJ, Dibble SL, Abrams DI (2008) Nausea at the end of adjuvant cancer treatment in relation to exercise during treatment in patients with breast cancer. Oncol Nurs Forum 35 (5): 830–5

    PubMed  Google Scholar 

  • Levine ME, Gillis MG, Koch SY et al. (2008) Protein and ginger for the treatment of chemotherapy-induced delayed nausea. J Altern Complement Med 14 (5): 545–51

    PubMed  Google Scholar 

  • Lilleby K, Garcia P, Gooley T et al. (2006) A prospective, randomized study of cryotherapy during administration of high-dose melphalan to decrease the severity and duration of oral mucositis in patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation. Bone Marrow Transplantation 37 (11): 1031–5

    CAS  PubMed  Google Scholar 

  • Lin KY, Hu YT, Chang KJ, Lin HF, Tsauo JY (2011) Effects of yoga on psychological health, quality of life, and physical health of patients with cancer: a meta-analysis. Evid Based Complement Alternat Med 2011: 659876

    Google Scholar 

  • Loprinzi CL, Cianflone SG, Dose AM et al. (1990) A controlled evaluation of an allopurinol mouthwash as prophylaxis against 5-FU-induced stomatitis. Cancer 65: 1879–1882

    CAS  PubMed  Google Scholar 

  • Lyles JN, Burish TG, Krozely MG et al. (1982) Efficiacy of relaxation training and guided imagery in reducing the adversiveness of cancer chemotherapy. J Consult Clin Psychol 50: 509–524

    CAS  PubMed  Google Scholar 

  • Mahood DJ, Dose AM, Loprinzi CL et al. (1991) Inhibition of fluorouracil-induced stomatitis by oral cryotherapy. Journal of Clinical Oncology 9 (3): 449–52

    CAS  PubMed  Google Scholar 

  • Manusirivithaya S, Sripramote M, Tangjitgamol S et al. (2004) Antiemetic effect of ginger in gynecologic oncology patients receiving cisplatin. Int J Gynecol Cancer 14 (6): 1063–9

    CAS  PubMed  Google Scholar 

  • Martinsen EW (2008) Physical activity in the prevention and treatment of anxiety and depression. Nord J Psychiatry 62 Suppl 47: 25–9

    PubMed  Google Scholar 

  • Mead GE, Morley W, Campbell P et al. (2008) Exercise for depression. Cochrane Database Syst Rev 4: CD004366

    PubMed  Google Scholar 

  • Mock V, Barton Burke M, Sheeran P et al. (1994) A nursing rehabilitation program for women with breast cancer receiving adjuvant chemotherapy. Oncol Nurs Forum 21: 899–907

    CAS  PubMed  Google Scholar 

  • Mock V, Dow KH, Meares CJ et al. (1997) Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum 24 (6): 991–1000

    CAS  PubMed  Google Scholar 

  • Mock V, Frangakis C, Davidson NE et al. (2005) Exercise manages fatigue during breast cancer treatment: a randomized controlled trial. Psychooncology 14 (6): 464–77

    PubMed  Google Scholar 

  • Molassiotis A (2000) A pilot study of the use of progressive muscle relaxation training in the management of post-chemotherapy nausea and vomiting. Eur J Cancer Care (Engl) 9: 230–234

    CAS  Google Scholar 

  • Molassiotis A, Yung Hilary P, Yam Bernard MC et al. (2002) The effectiveness of progressive muscle relaxation training in managing chemotherapy-induced nausea and vomiting in Chinese breast cancer patients: A randomised control trial. Support Care Cance 10: 237–246

    Google Scholar 

  • Molassiotis A, Helin AM, Dabbour R, Hummerston S (2007) The effects of P6 acupressure in the prophylaxis of chemotherapy-related nausea and vomiting in breast cancer patients. Complement Ther Med 15 (1): 3–12

    CAS  PubMed  Google Scholar 

  • Molassiotis A, Sylt P, Diggins H (2007) The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial. Complement Ther Med 15 (4): 228–37

    PubMed  Google Scholar 

  • Monga U, Garber SL, Thornby J et al. (2007) Exercise prevents fatigue and improves quality of life in prostate cancer patients undergoing radiotherapy. Arch Phys Med Rehabil 88 (11): 1416–22

    PubMed  Google Scholar 

  • Montgomery GH, Weltz CR, Seltz M et al. (2002) Brief presurgery hypnosis reduces distress and pain in excisional breast biopsy patients. Int J Clin Exp Hypn 50: 17–32

    PubMed  Google Scholar 

  • Mori T, Hasegawa K, Okabe A et al. (2008) Efficacy of mouth rinse in preventing oral mucositis in patients receiving high-dose cytarabine for allogeneic hematopoietic stem cell transplantation. Int J Hematol [Epub ahead of print]

    Google Scholar 

  • National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology: Cancer-related fatigue. Version 4.2007. www.nccn.org

  • Nedstrand E, Wijma K, Wyon Y, Hammar M (2005) Applied relaxation and oral estradiol treatment of vasomotor symptoms in postmenopausal women. Maturitas 51 (2): 154–62

    CAS  PubMed  Google Scholar 

  • Nedstrand E, Wyon Y, Hammar M, Wijma K (2006) Psychological well-being improves in women with breast cancer after treatment with applied relaxation or electro-acupuncture for vasomotor symptom. J Psychosom Obstet Gynaecol 27 (4): 193–9

    PubMed  Google Scholar 

  • Newton RU, Galvão DA (2008) Exercise in prevention and management of cancer. Curr Treat Options Oncol 9 (2–3): 135–46

    PubMed  Google Scholar 

  • Oberbaum M, Yaniv I, Ben-Gal Y et al. (2001) A randomized, controlled clinical trial of the homeopathic medication TRAUMEEL S in the treatment of chemotherapy-induced stomatitis in children undergoing stem cell transplantation. Cancer 92 (3): 684–90

    CAS  PubMed  Google Scholar 

  • Pace A, Savarese A, Picardo M et al. (2003) Neuroprotective effect of vitamin E supplementation in patients with cisplatin chemotherapy. J Clin Oncol 21: 927–931

    CAS  PubMed  Google Scholar 

  • Paley CA, Johnson MI, Tashani OA, Bagnall AM (2011) Acupuncture for cancer pain in adults. Cochrane Database Syst Rev. (1):CD007753

    Google Scholar 

  • Phillips KD, Skelton WD, Hand GA (2004) Effect of acupuncture administered in a group setting on pain and subjective peripheral neuropathy in persons with human immunodeficiency virus disease. Journal of Alternative and Complementary Medicine 10 (3): 449–455

    Google Scholar 

  • Pirl WF, Greer JA, Goode M, Smith MR (2008) Prospective study of depression and fatigue in men with advanced prostate cancer receiving hormone therapy. Psychooncology 17 (2): 148–53

    PubMed Central  PubMed  Google Scholar 

  • Preuss HG, Marcusen C, Regan J et al. (2001) Randomized trial of a combination of natural products (cernitin, saw palmetto, B-sitosterol, vitamin E) on symptoms of benign prostatic hyperplasia (BPH). Int Urol Nephrol 33 (2): 217–25

    CAS  PubMed  Google Scholar 

  • Raedsch R, Hanisch J, Bock P et al. (2007) Assessment of the efficacy and safety of the phytopharmacon STW 5 versus metoclopramide in functional dyspepsia–a retrolective cohort study. Z Gastroenterol 45 (10): 1041–8

    CAS  PubMed  Google Scholar 

  • Richardson J, Smith JE, McCall G et al. (2007) Hypnosis for nausea and vomiting in cancer chemotherapy: a systematic review of the research evidence. Eur J Cancer Care (Engl) 16 (5): 402–12

    CAS  Google Scholar 

  • Rico RC, Trudnowski RJ (1992) Studies with electro-acupuncture. J Med 13: 247–251

    Google Scholar 

  • Ryan JL et al. (2007) Mechanisms of cancer-related fatigue. Review. Oncologist 12 (Suppl 1): 22–34

    CAS  PubMed  Google Scholar 

  • Rydholm M, Strang P (1999) Acupuncture for patients in hospital-based home care suffering from xerostomia. J Palliat Care 15 (4): 20–3

    CAS  PubMed  Google Scholar 

  • Schwartz AL, Mori M, Gao R et al. (2001) Exercise reduces daily fatigue in women with breast cancer receiving chemotherapy. Med Sci Sports Exerc 33 (5): 718–23

    CAS  PubMed  Google Scholar 

  • Sharplin GR, Jones SB, Hancock B et al. (2010) Mindfulness-based cognitive therapy: an efficacious community-based group intervention for depression and anxiety in a sample of cancer patients. Med J Aust 193 (5 Suppl):S79–82

    Google Scholar 

  • Shlay JC, Chaloner K, Max MB et al. (1998) Acupuncture and Amitriptyline for Pain Due to HIV-Related Peripheral Neuropathy. A Randomized Controlled Trial. JAMA 280 (18): 1590–1595

    CAS  PubMed  Google Scholar 

  • Silberstein JL, Parsons JK (2010) Evidence-based principles of bladder cancer and diet. Urology 75 (2): 340–6

    PubMed  Google Scholar 

  • Siswanto et al. (2006) Patients with cisplatin-induced peripheral neuropathy are characterized by a low plasma level of vitamin E Annals of Oncology 17 (Suppl 9): 298–298

    Google Scholar 

  • Sonis S, kunz A (1988) Impact of improved dental services on the frequency of oral complications of cancer therapy for patients with non-head-and-neck malignancies. Oral Surg Oral Med Oral Pathol 65: 19–22

    CAS  PubMed  Google Scholar 

  • Sontakke et al. (2003) Ginger was an antiemetic in nausea and vomiting induced by chemotherapy – A randomized cross-over, double blind study. Indian Journal of Pharmacology 35 (1): 32–36

    Google Scholar 

  • Sorensen JB, Skovsgaard T, Bork E et al. (2006) Prophylaxis of chemotherapy-induced oral mucositis: Double blind placebo-controlled randomized study of chlorhexidine versus placebo and with nonblinded randomized comparison to oral cooling (cryotherapy). Annals of Oncology 17 (Suppl 9): 286

    Google Scholar 

  • Spahn G, Paul A, Dobos G et al. (2003) Improvement of fatigue and role function of cancer patients after an outpatient integrative mind/body intervention. FACT 8: 540

    Google Scholar 

  • Stone P, Richardson A, Ream E et al. (2000) Cancer-related fatigue: inevitable, unimportant and untreatable? AnnOncol 11: 971–975

    CAS  Google Scholar 

  • Ströhle A (2008) Physical activity, exercise, depression and anxiety disorders. J Neural Transm [Epub ahead of print]

    Google Scholar 

  • Sutton LM, Porter LS, Keefe FJ (2002) Cancer pain at the end of life: a biopsychosocial perspective. Pain 99: 5–10

    PubMed  Google Scholar 

  • Svanberg A, Birgegård G, Ohrn K (2007) Oral cryotherapy reduces mucositis and opioid use after myeloablative therapy – a randomized-controlled trial. Supportive Care Cancer 15: 1155–1161

    Google Scholar 

  • Syrjala KL, Donaldson GW, Davis MW et al. (1995) Relaxation and imagery and cognitive-behavioral training reduce pain during cancer treatment: a controlled clinical trial. Pain 63 (2): 189–98

    CAS  PubMed  Google Scholar 

  • Tang L, Zirpoli GR, Guru K et al. (2010) Intake of cruciferous vegetables modifies bladder cancer survival. Cancer Epidemiol Biomarkers Prev 19 (7): 1806–11

    CAS  PubMed Central  PubMed  Google Scholar 

  • Tsavaris N, Caragiauris P, Kosmidis P (1988) Reduction of oral toxicity of 5-FU by allopurinol mouthwashes. Eur J Surg Oncol 14: 405–406

    CAS  PubMed  Google Scholar 

  • Van der Lee ML, Garssen B (2010) Mindfulness-based cognitive therapy reduces chronic cancer-related fatigue: a treatment study. Psychooncology 2010 Dec 19. [Epub ahead of print]

    Google Scholar 

  • Vasterling J, Jenkins RA, Tope DM et al. (1993) Cognitive distraction and relaxation training for the control of side effects due to cancer chemotherapy. J Behav Med 16: 65–80

    CAS  PubMed  Google Scholar 

  • Vickers AJ, Straus DJ, Fearon B, Cassileth BR (2004) Acupuncture for postchemotherapy fatigue: a phase II study. J Clin Oncol 22 (9): 1731–5

    PubMed  Google Scholar 

  • Visovsky C, Collins M, Abbott L et al. (2007) Evidence-based interventions for chemotherapy-induced peripheral neuropathy. Clinical Journal of Oncology Nursing 11 (6): 901–913

    PubMed  Google Scholar 

  • Vogelzang NJ, Breitbart W, Cella D et al. (1997) Patient, caregiver, and oncologist perceptions of cancer-related fatigue. Semin Hematol 34 (suppl 2): 4–12

    CAS  PubMed  Google Scholar 

  • Wadleigh RG, Redman RS, Graham ML et al. (1992) Vitamin E in the treatment of chemotherapy-induced mucositis. Am J Med 92: 481–484

    CAS  PubMed  Google Scholar 

  • Wang J (2002) Effect on Chinese herbs decoction gargling to treat and to prevent chemotherapy caused stomatitis. Chinese Nursing Research 16 (10): 578–9

    Google Scholar 

  • Wilke DJ, Kampbell J, Cutshall S et al. (2000) Effects of massage on pain intensity, analgesics and quality of life in patients with cancer pain: a pilot study of a randomized clinical trial conducted within hospice care delivery. Hosp J 15 (3): 31–53

    Google Scholar 

  • Wilt T, Ishani A, Mac Donald R (2002) Serenoa repens for benign prostatic hyperplasia. Cochrane Database Syst Rev 3: CD001423

    PubMed  Google Scholar 

  • Wilt T, Ishani A, Mac Donald R et al. (2002) Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 1: CD001044

    PubMed  Google Scholar 

  • Wilt T, Mac Donald R, Ishani A, Rutks I, Stark G (2000) Cernilton for benign prostatic hyperplasia. Cochrane Database Syst Rev 2: CD001042

    PubMed  Google Scholar 

  • Windsor PM, Nicol KF, Potter J (2004) A randomized, controlled trial of aerobic exercise for treatment-related fatigue in men receiving radical external beam radiotherapy for localized prostate carcinoma. Cancer 101 (3): 550–7

    PubMed  Google Scholar 

  • Winningham ML, MacVicar MG (1988) The effect of aerobic exercise on patient reports of nausea. Oncol Nurs Forum 15: 447–450

    CAS  PubMed  Google Scholar 

  • Wong R, Sagar S (2006) Acupuncture treatment for chemotherapy-induced peripheral neuropathy–a case series. Acupunct Med 24 (2): 87–91

    PubMed  Google Scholar 

  • Worthington HV, Clarkson JE, Eden TOB (2007) Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev 4: CD000978

    PubMed  Google Scholar 

  • Wyon Y, Wijma K, Nedstrand E, Hammar M (2004) A comparison of acupuncture and oral estradiol treatment of vasomotor symptoms in postmenopausal women. Climacteric 7 (2): 153–64

    CAS  PubMed  Google Scholar 

  • Xia Y, Zhang D, Yang C et al. (1986) An approach to the effect on tumors of acupuncture in combination with radiotherapy or chemotherapy. J Tradit Chin Med 6: 23–26

    CAS  PubMed  Google Scholar 

  • Zaza C, Baine N (2002) Cancer pain and psychosocial factors: a critical review of the literature. J Pain Symtpom Manage 24: 526–542

    Google Scholar 

  • Zhang et al. (2007) Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients. Cochrane Database Syst Rev 2: CD004921

    Google Scholar 

  • Zick SM, Ruffin MT, Lee J et al. (2008) Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting. Support Care Cancer [Epub ahead of print]

    Google Scholar 

Literatur zu ▶ Abschn. 16.12

  • AHCPR Publication (1992) 92–0032: 100–107

    Google Scholar 

  • Blanchard CM, Courneya KS, Stein K; American Cancer Society’s SCS-II (2008) Cancer survivors’ adherence to lifestyle behavior recommendations and associations with health-related quality of life: results from the American Cancer Society’s SCS-II. J Clin Oncol 26 (13): 2198–204

    PubMed  Google Scholar 

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Sütfels, G., Saha, F., Altner, N., Dobos, G. (2014). Komplementäre Therapieverfahren. In: Rübben, H. (eds) Uroonkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35032-0_16

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