Variety of Cortical Pathways Formed by Topographic Neural Projection: A Computational Study
Different areas in the brain are specialized for different functions, and complex cognitive tasks are implemented by their cooperation. Recently, cortico-cortical network structures have been analyzed based on graph theory, but further details of structures of neuron-level networks that are essential for implementing cognitive functions are still unclear. In this study, under a hypothesis of heritable topographical projections between cortical areas, the ability to form neuron-level pathways with topographical projection was evaluated by computer simulations. In the results, a segmented and compressed projection was found to produce a wider variety of neuronal pathways through cortical areas in comparison to other projection structures. This suggests that topographic neuronal projection is a basis for anatomically neuron-level pathways that relay signals to a set of specific cortical areas.
Keywordsbrain cerebral cortex computational model anatomical projection self-organization
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